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Sequential treatment for diabetic foot ulcers in dialysis patients:A case report

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World Journal of Diabetes 2023年第8期14卷 1323-1329页

作者： Jin-Jun Wang Yuan-Yuan Yu Pin-Yi Wang xian-ming huang Xiao Chen Xi-Guang Chen College of Marine Life Science Ocean University of ChinaQingdao 266003Shandong ProvinceChina Department of Vascular Surgery Qingdao Haici Hospital Affiliated to Qingdao UniversityQingdao 266033Shandong ProvinceChina

BACKGROUND Diabetic foot ulcers(DFUs)are common in patients with diabetes,especially those undergoing *** severe cases,these ulcers can cause damage to the lower extremities and lead to *** treatments such as flap transposition and transfemoral amputation are not always applicable in all ***,there is a need for alternative treatment *** SUMMARY This report describes a 62-year-old female patient who was admitted to the hospital with plantar and heel ulcers on her left *** patient had a history of renal failure and was undergoing regular *** subtraction angiography showed extensive stenosis and occlusion in the left superficial femoral artery,left peroneal artery and left posterior tibial *** evaluation by a multidisciplinary team,the patient was diagnosed with type 2 DFUs(TEXAS 4D).Traditional treatments were deemed unsuitable,and the patient was treated with endovascular surgery in the affected area,in addition to supportive medical treatment,local debridement,and sequential repair using split-thickness skin and tissue-engineered skin grafts combined with negative pressure *** four months,the wound had completely healed,and the patient was able to walk with a walking *** This study demonstrates a new treatment method for DFUs was successful,using angioplasty,skin grafts,and negative pressure.

关键词： Diabetic foot Dialysis Plantar and heel ulcers Percutaneous transluminal angioplasty Tissue-engineered skin Wound repair Case report

Insights into spinal muscular atrophy from molecular biomarkers

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Neural Regeneration Research 2025年第7期20卷 1849-1863页

作者： Xiaodong Xing Xinzhu Liu xiandeng Li Mi Li xian Wu Xiaohui huang Ajing Xu Yan Liu Jian Zhang Department of Clinical Pharmacy Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghaiChina College of Pharmacy Chongqing Medical UniversityChongqingChina

Spinal muscular atrophy is a devastating motor neuron disease characterized by severe cases of fatal muscle *** is one of the most common genetic causes of mortality among infants aged less than 2 *** research is currently receiving more attention,and new candidate biomarkers are constantly being *** review initially discusses the evaluation methods commonly used in clinical practice while briefly outlining their respective pros and *** also describe recent advancements in research and the clinical significance of molecular biomarkers for spinal muscular atrophy,which are classified as either specific or non-specific *** review provides new insights into the pathogenesis of spinal muscular atrophy,the mechanism of biomarkers in response to drug-modified therapies,the selection of biomarker candidates,and would promote the development of future ***,the successful utilization of biomarkers may facilitate the implementation of gene-targeting treatments for patients with spinal muscular atrophy.

关键词： biomarkers disease progression gene-targeting therapy neurofilaments Nusinersen spinal muscular atrophy(SMA) survival motor neuron therapeutic evaluation treatment outcomes

大尺度流域不同地貌类型区水土保持减水效益分析

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水土保持学报 2001年第1期15卷 90-94页

作者：刘贤赵黄明斌中国科学院水利部水土保持研究所陕西杨陵712100

趋势分析结果显示 ,河源涧区、风沙区、丘陵区各代表流域年径流量均在 1970年前后发生一致性改变 ,即从 1970年以来开始有明显的减少趋势 ,平均减流幅度 (与 195 9～ 196 9年径流相比 )以河源涧区 (大理河 )和丘陵区 (小理河 )最大 ,分... 详细信息

趋势分析结果显示 ,河源涧区、风沙区、丘陵区各代表流域年径流量均在 1970年前后发生一致性改变 ,即从 1970年以来开始有明显的减少趋势 ,平均减流幅度 (与 195 9～ 196 9年径流相比 )以河源涧区 (大理河 )和丘陵区 (小理河 )最大 ,分别为 36 .33%和 36 .2 1% ,风沙区 (海流兔河 )最小 (2 0 .6 1% )。减流幅度的大小是各类型区下垫面状况、水土保持措施和治理程度、降雨量变化等多种因素综合作用的结果。借助适合于黄土高原降雨 -产流特性的月水量平衡改进模型 ,计算天然状态下降雨应有的产流量与同期实测径流量求得减水效果。结果表明 ,3个地貌类型区 70年代的减水效益没有明显差异 ,而在 80年代减水效果差异显著 ,丘陵区 (小理河 ,2 4.99% ) >风沙区 (海流兔河 ,17.2 8% ) >河源涧区 (大理河 ,13.13% )。上述结论为定量评价黄土高原生态环境建设对黄河水资源及水环境演变的影响提供了数据基础。

关键词：大尺度流域地貌类型区水土保持减水效益

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绉纹整理对真丝织物结构与风格的影响

丝绸 2001年第11期38卷 16-17页

作者：李维贤师严明黄志君蒋小葵华南农业大学艺术设计学院广东广州510642 南充市出入境检验检疫局四川南充637000

对绉纹整理的真丝电力纺的结构、外观风格进行研究。结果表明 ,所用的后整理方法起绉效果明显 ,整理后织物的结构变得紧密、厚实 ,织物风格发生了显著的变化 ,即纹理由细腻变得粗犷 ,手感由平滑变得丰满而挺爽 ,富有弹性。

关键词：丝织物绉纹整理结构风格

GPIO-Based Continuous Sliding Mode Control for Networked Control Systems Under Communication Delays With Experiments on Servo Motors

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IEEE/CAA Journal of Automatica Sinica 2025年第1期 99-113页

作者： Kamal Rsetam Zhenwei Cao Zhihong Man xian-ming Zhang the School of Software and Electrical Engineering Swinburne University of Technology the Department of Automated Manufacturing Al Khwarizmi College of Engineering University of Baghdad IEEE

To handle input and output time delays that commonly exist in many networked control systems(NCSs), a new robust continuous sliding mode control(CSMC) scheme is proposed for the output tracking in uncertain single input-single-output(SISO) networked control systems. This scheme consists of three consecutive steps. First, although the network-induced delay in those systems can be effectively handled by using Pade approximation(PA), the unmatched disturbance cames out as another difficulty in the control design. Second, to actively estimate this unmatched disturbance, a generalized proportional integral observer(GPIO) technique is utilized based on only one measured state. Third, by constructing a new sliding manifold with the aid of the estimated unmatched disturbance and states, a GPIO-based CSMC is synthesized, which is employed to cope with not only matched and unmatched disturbances, but also networkinduced delays. The stability of the entire closed-loop system under the proposed GPIO-based CSMC is detailedly *** promising tracking efficiency and feasibility of the proposed control methodology are verified through simulations and experiments on Quanser's servo module for motion control under various test conditions.

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Polystyrene-supported Benzyl Selenide: An Efficient Reagent for Highly Stereocontrolled Synthesis of Substituted Olefins

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Chinese Chemical Letters 2003年第4期14卷 335-337页

作者： Wei ming XU Li ming YU xian huang Department of Chemistry Zhejiang University(Xixi Campus)Hangzhou 310028

Polystyrene-supported benzyl selenide has been prepared. This novel reagent was treated with LDA to produce a selenium stabilized carbanion, which reacted with alkyl halide, followed by selenoxide syn-elimination, to... 详细信息

关键词： Solid phase synthesis polystyrene-supported benzyl selenide substituted olefins.

Role of nutrition in diabetes mellitus and infections

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World Journal of Clinical Cases 2025年第3期13卷 1-8页

作者： Xue-Lu Yu Li-Yun Zhou Xiao huang Xin-Yue Li ming-Ke Wang Ji-Shun Yang Naval Medical Center of PLA Naval Medical UniversityShanghai 200052China

In this editorial,we have commented on the article that has been published in the recent issue of World Journal of Clinical *** authors have described a case of unilateral thyroid cyst and have opined that the acute onset of infection may be linked to diabetes mellitus(DM).We have focused on the role of nutrition in the association between DM and *** with DM are at a high risk of infection,which could also be attributed to nutrition-related *** interventions for patients with diabetes are mainly based on a low-calorie diet,which can be achieved by adhering to a low-carbohydrate ***,dietary fiber supplementation is recommended to maintain the diversity of the gut ***,high-quality protein can prevent the increased risk of infection due to *** of vitamins C,vitamins A,vitamins D,and folic acid improves blood sugar control and facilitates immune *** deficiencies augment the risk of infection,but the relationship with diabetes is mostly U-shaped and a good intake should be maintained.

关键词： Diabetes mellitus Infection Macronutrients Vitamins Minerals

超渗超蓄产流模型在评价水保措施减水效益中的应用

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山地学报 2002年第2期20卷 218-222页

作者：刘贤赵黄明斌李玉山中国科学院水利部水土保持研究所中国科学院水利部水土保持研究所陕西杨陵712100

根据治理与尺度对黄土区产流模式的影响 ,建立用地评价水土保持的措施减水效益的超蓄产流模型 ,并将径流成份直接区分为地表径流和地下径流。同时着重介绍所建模型参数的率定及其在减水效益中的应用。在3个典型流域 (青阳岔、岔巴沟和... 详细信息

根据治理与尺度对黄土区产流模式的影响 ,建立用地评价水土保持的措施减水效益的超蓄产流模型 ,并将径流成份直接区分为地表径流和地下径流。同时着重介绍所建模型参数的率定及其在减水效益中的应用。在3个典型流域 (青阳岔、岔巴沟和小理河 )的应用结果表明 ,该模型效果良好 ,具有较好的应用前景

关键词：超渗-超蓄产流模型水保效益评价减水

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海上救援无人方舱水动力性能分析

大连理工大学学报 2025年第1期65卷 56-66页

作者：李铁骊黄珍秋周燹大连理工大学船舶工程学院辽宁大连116024

空投方舱的方形系数过大,使得方舱在航行时艏摇、横摇、纵摇严重,水动力性能较差,需针对方舱的入水航行问题进行水动力性能分析,并为其设计优选附体,改善方舱的稳定性.根据确定的方舱主尺度、船型参数以及重心位置可行域,利用CFD方法研... 详细信息

空投方舱的方形系数过大,使得方舱在航行时艏摇、横摇、纵摇严重,水动力性能较差,需针对方舱的入水航行问题进行水动力性能分析,并为其设计优选附体,改善方舱的稳定性.根据确定的方舱主尺度、船型参数以及重心位置可行域,利用CFD方法研究方舱的水动力性能,包括快速性、耐波性、航向稳定性等,为方舱设计并优化附体.其中快速性方面,计算固定吃水、纵倾时的阻力以及空载、设计载况下放开纵摇和垂荡的静水阻力;耐波性主要计算空载、设计载况下的波浪增阻和自由横摇衰减时间,增加舭龙骨以改善横摇稳定性;航向稳定性主要计算方舱艏摇衰减时间,并加装艏艉鳍改善其航向稳定性;最后对加装优选附体的方舱进行分析对比,并完成实船阻力、功率预估.通过加装附体的方式对方舱进行优化,水动力性能分析证明了其动力和推进系统可行性,初步确定加装优选附体的方舱模型,为后续总体设计及其设备选取提供技术参考.

关键词：无人艇救援方舱水动力性能快速性耐波性航向稳定性附体优化设计