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Deterministic assembly of single optical cavity formed by gold dimensional DNA origami

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Nano Research 2022年第2期15卷 1327-1337页

作者： Zhi Zhao xiahui chen Jiawei Zuo Ali Basiri Shinhyuk Choi Yu Yao Yan Liu Chao Wang Center for Molecular Design and Biomimetics at the Biodesign Institute Arizona State UniversityTempeArizona 85287USA School of Molecular Sciences Arizona State UniversityTempeAZ 85287USA School of Electrical Computer and Energy EngineeringArizona State UniversityTempeAZ 85287USA Faculty of Materials and Manufacturing Key Laboratory of Advanced Functional MaterialsEducation Ministry of ChinaBeijing University of TechnologyBeijing 100124China

Controllable strong interactions between a nanocavity and a single emitter is important to manipulating optical emission in a nanophotonic system but challenging to *** a three-dimensional DNA origami,named as DNA rack(DR)is proposed and demonstrated to deterministically and precisely assemble single emitters within ultra-small plasmonic nanocavities formed by closely coupled gold nanorods(AuNRs).Uniquely,the DR is in a saddle shape,with two tubular grooves that geometrically allow a snug fit and linearly align two AuNRs with a bending angle <10°.It also includes a spacer at the saddle point to maintain the gap between AuNRs as small as 2-3 nm,forming a nanocavity estimated to be 20 nm^(3) and an experimentally measured O factor of 7.3.A DNA docking strand is designed at the spacer to position a single fluorescent emitter at nanometer accuracy within the *** Cy5 as a model emitter,a -30-fold fluorescence enhancement and a significantly reduced emission lifetime(from 1.6 ns to 670 ps)were experimentally verified,confirming significant emitter-cavity *** DR-templated assembly method is capable of fitting AuNRs of variable length-to-width aspect ratios to form anisotropic nanocavities and deterministically incorporate different single emitters,thus enabling flexible design of both cavity resonance and emission wavelengths to tailor light-matter interactions at nanometer scale.

关键词： DNA origami self-assembly deterministic single emitter plasmonic nanocavity nanorod dimer optical coupling

Nature-inspired chiral metasurfaces for circular polarization detection and full-Stokes polarimetric measurements

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Light(Science & Applications) 2019年第1期8卷 494-504页

作者： Ali Basiri xiahui chen Jing Bai Pouya Amrollahi Joe Carpenter Zachary Holman Chao Wang Yu Yao School of Electrical Computer and Energy EngineeringArizona State UniversityTempeAZ 85281USA Centre for Photonic Innovation Arizona State UniversityTempeAZ 85281USA Biodesign Centre for Molecular Design&Biomimetics Arizona State UniversityTempeAZ 85281USA

The manipulation and characterization of light polarization states are essential for many applications in quantum communication and computing,spectroscopy,bioinspired navigation,and *** metamaterials and metasurfaces facilitate ultracompact devices for circularly polarized light generation,manipulation,and ***,we report bioinspired chiral metasurfaces with both strong chiral optical effects and low insertion *** experimentally demonstrated submicron-thick circularly polarized light filters with peak extinction ratios up to 35 and maximum transmission efficiencies close to 80% at near-infrared wavelengths(the best operational wavelengths can be engineered in the range of 1.3-1.6μm).We also monolithically integrated the microscale circular polarization filters with linear polarization filters to perform full-Stokes polarimetric measurements of light with arbitrary polarization *** the advantages of easy on-chip integration,ultracompact footprints,scalability,and broad wavelength coverage,our designs hold great promise for facilitating chip-integrated polarimeters and polarimetric imaging systems for quantum-based optical computing and information processing,circular dichroism spectroscopy,biomedical diagnosis,and remote sensing applications.

关键词： polarization circular polar

Chip-integrated plasmonic flat optics for mid-infrared full-Stokes polarization detection

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Photonics Research 2019年第9期7卷 1051-1060页

作者： JING BAI CHU WANG xiahui chen ALI BASIRI CHAO WANG YU YAO School of Electrical Computer and Energy EngineeringArizona State UniversityTempeArizona85281USA Center for Photonic Innovation Arizona State UniversityTempeArizona85281USA Biodesign Center for Molecular Design&Biomimetics Arizona State UniversityTempeArizona85281USA

Flat optics presents a new path to control the phase, amplitude, and polarization state of light with ultracompact devices. Here we demonstrate chip-integrated metasurface devices for polarization detection of mid-infrared light with arbitrary polarization states. Six high-performance microscale linear and circular polarization filters based on vertically stacked plasmonic metasurfaces(with total thickness <600 nm) are integrated on the same chip to obtain all four Stokes parameters of light with high accuracy. The device designs can be tailored to operate at any wavelength in the mid-infrared spectral region and are feasible for on-chip integration with mid-infrared(mid-IR) photodetectors and imager arrays. Our work will enable on-chip mid-IR polarimeters and polarimetric imaging systems, which are highly desirable for many applications, such as clinical diagnosis, target detection, and space exploration.

关键词： red LCP RCP Stokes Chip-integrated plasmonic flat optics for mid-infrared full-Stokes polarization detection

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无黏结预应力装配式框架结构地震易损性分析

哈尔滨工业大学学报 2018年第6期50卷 71-77页

作者：潘毅陈侠辉王涵平赵崇锦西南交通大学土木工程学院成都610031 抗震工程技术四川省重点实验室(西南交通大学) 成都610031 中铁第六勘察设计院集团有限公司天津300308

为研究无黏结预应力装配式框架结构的抗震性能,首先采用有限元软件Open SEES中的梁柱节点单元模拟无黏结预应力梁柱节点,并与试验结果进行验证.然后,按照场地条件选取18条地震动记录,以预应力筋屈服和最大层间位移角作为结构的损伤指标... 详细信息

为研究无黏结预应力装配式框架结构的抗震性能,首先采用有限元软件Open SEES中的梁柱节点单元模拟无黏结预应力梁柱节点,并与试验结果进行验证.然后,按照场地条件选取18条地震动记录,以预应力筋屈服和最大层间位移角作为结构的损伤指标,建立地震需求模型.最后,采用IDA方法对一栋6层无黏结预应力装配式框架结构和现浇框架结构进行易损性分析,得到两种结构的IDA曲线和易损性曲线.研究结果表明:在水平地震作用下,柱截面尺寸和配筋相同、梁截面尺寸和受弯承载力相同时,在防止倒塌性态点处,装配式结构的最大层间位移角和地震动强度指标均小于现浇结构;当地震动强度较小时,装配式框架结构和现浇框架结构的抗倒塌能力接近,但随着地震动强度的增大,在防止倒塌性态点处,装配式框架结构的抗倒塌能力比现浇框架结构弱.

关键词：预应力装配式框架梁柱节点增量动力分析(IDA) 地震易损性

Bone Marrow-Derived Mesenchymal Stem Cells Attenuates Lung Inflammation and up-regulate protective cytokine IL-10 and IL-12 in asthmtic Mice model

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Bone Marrow-Derived Mesenchymal Stem Cells Attenuates Lung I...

中华医学会呼吸病学年会——2011（第十二次全国呼吸病学学术会议）

作者： xiahui Ge,Ruohua chen,Jianmin Yang,Chong Bai,Guoliang Lou,Zhenli Hu,Qiang Li Changhai Hospital,the Second Military Medical University

Recent study prove that Mesenchymal Stem Cells(MSCs)attenuate the severity of lung injury due to its immunomodulatory *** this study,we test the immunoregulatory features of administrating BMSCs on ovalbumin-induced asthma mice by intrapulmonary *** female BALB /c mice were equally randomized into normal control group,BMSCs treatment group,BMSCs

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阿湖水库溢洪道扩建工程设计研究

水利科学与寒区工程 2018年第3期1卷 9-12页

作者：夏辉徐波陈伟江苏省水利勘测设计研究院有限公司江苏扬州225217 扬州大学水利与能源动力工程学院江苏扬州225009

为解决阿湖水库蓄水与防洪矛盾,保证水库防洪安全,本文通过比较两种方案在投资、施工、管理等方面的优缺点,优选出溢洪道扩建方案。优选方案具有较好的适应能力并可以适当降低工程造价。

关键词：溢洪道隧洞方案比选设计方案

P16^(INK4a)与人乳头瘤病毒感染及宫颈上皮内瘤变进展的相关性

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中国医科大学学报 2024年第9期53卷 777-781页

作者：陈霞慧马向薇郝冬梅于月新中国人民解放军北部战区总医院生殖医学科沈阳110003

目的探讨P16^(INK4a)与人乳头瘤病毒(HPV)感染及宫颈上皮内瘤变(CIN)的相关性。方法选取2020年2月至2023年5月在我院就诊的CIN患者197例(CIN组),其中CIN1患者62例,CIN2患者89例,CIN3患者46例;同时选取接受子宫全切除术且术后病理证实宫... 详细信息

目的探讨P16^(INK4a)与人乳头瘤病毒(HPV)感染及宫颈上皮内瘤变(CIN)的相关性。方法选取2020年2月至2023年5月在我院就诊的CIN患者197例(CIN组),其中CIN1患者62例,CIN2患者89例,CIN3患者46例;同时选取接受子宫全切除术且术后病理证实宫颈组织正常患者50例作为对照组;检测2组P16^(INK4a)表达及HPV感染情况。结果对照组P16^(INK4a)阳性表达率和HPV感染率(10.00%和0.00%)显著低于CIN组(72.08%和45.69%,P0.05)。结论CIN患者P16^(INK4a)表达率明显升高,且与病变程度相关,P16^(INK4a)表达与HPV感染有关。

关键词： P16^(INK4a) 人乳头瘤病毒宫颈上皮内瘤变相关性

深度氧化技术系统在高难废水处理中的应用研究

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水处理技术 2013年第11期39卷 114-116页

作者：吴开元陈霞辉顾秋月张黠宋洋周印化工部长沙设计研究院湖南长沙410116

采用深度氧化技术（HPOD）系统对己内酰胺废水、苯酚废水和印染废水等高难废水进行了深度化学处理系统工程试验研究。结果表明，当进水COD为100～150mg／L、色度为150~380倍时，经HPOD系统处理后出水水质COD~60mg／L，色度≤50倍，完全... 详细信息

采用深度氧化技术（HPOD）系统对己内酰胺废水、苯酚废水和印染废水等高难废水进行了深度化学处理系统工程试验研究。结果表明，当进水COD为100～150mg／L、色度为150~380倍时，经HPOD系统处理后出水水质COD~60mg／L，色度≤50倍，完全达到GB8978—1996城镇二级污水处理厂一级排放标准：且HPOD系统运行良好，具备良好的稳定性和高效性，同时设备占地面积小、投资省、操作简便、成本低廉，在难生物降解、含油、有毒有害废水的深度净化处理中具有广阔的推广应用前景。

关键词：深度氧化高难废水水处理应用

O、A、Asia 1型口蹄疫病毒胶体金定量检测免疫层析方法的建立

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畜牧兽医学报 2021年第4期52卷 1042-1052页

作者：李昕孙燕燕林密陈夏辉李峰松包艳芳杨光蒋韬中国农业科学院兰州兽医研究所兰州730046

旨在建立口蹄疫病毒(foot-and-mouth disease virus, FMDV)抗原血清型的快速分型和定量的检测方法,利用双抗体夹心法,将口蹄疫病毒的兔抗及豚鼠抗体作为标记胶体金与NC膜检测带的原料,分别制备出检测O、A、Asia 1血清型的3种层析试纸卡... 详细信息

旨在建立口蹄疫病毒(foot-and-mouth disease virus, FMDV)抗原血清型的快速分型和定量的检测方法,利用双抗体夹心法,将口蹄疫病毒的兔抗及豚鼠抗体作为标记胶体金与NC膜检测带的原料,分别制备出检测O、A、Asia 1血清型的3种层析试纸卡。通过对标定的抗原标准品146S检测,拟合出定量标准曲线。免疫层析方法的质量验证通过特异性、敏感性、重复性及与蔗糖密度梯度法(sucrose density gradient, SDG)的相关性进行评价。结果显示:建立的快速定量检测方法,3种血清型口蹄疫病毒间无交叉反应,同时与其他非口蹄疫病毒,如塞内卡病毒A型(SVA)、猪水疱病病毒(SVDV)、猪水疱性口炎病毒(VSV)无非特异反应;敏感性研究,对O、A、Asia 1型病毒的最低检出量分别为0.567、0.693、0.219μg·mL^(-1),拟合的3条标准曲线的线性相关系数R~2>0.97,新建立方法与蔗糖密度梯度法检测结果的相关系数均>0.9, 3种层析试纸卡的变异系数均小于10%。综上表明,建立的口蹄疫O、A、Asia1型病毒胶体金免疫层析定量检测试纸卡方法,可以用于口蹄疫病毒抗原快速鉴别、血清分型与146S定量检测。

关键词：口蹄疫病毒胶体金免疫层析定量检测 146S