检索结果-南通市图书馆

Perilipin-2 mediates ferroptosis in oligodendrocyte progenitor cells and myelin injury after ischemic stroke

Neural Regeneration Research 2025年第7期20卷 2015-2028页

作者： Jian Yang Jiang Wu Xueshun Xie Pengfei xia.Jinxin lu Jiale Liu Lei Bai xia.g Li Zhengquan Yu Haiying Li Department of Neurosurgery&Brain and Nerve Research Laboratory The First Affiliated Hospital of Soochow UniversitySuzhouJiangsu ProvinceChina Institute of Stroke Research Soochow UniversitySuzhouJiangsu ProvinceChina

Differentiation of oligodendrocyte progenitor cells into mature myelin-forming oligodendrocytes contributes to *** of remyelination due to oligodendrocyte progenitor cell death can result in severe nerve *** is an iron-dependent form of regulated cell death caused by membrane rupture induced by lipid peroxidation,and plays an important role in the pathological process of ischemic ***,there are few studies on oligodendrocyte progenitor cell *** analyzed transcriptome sequencing data from GEO databases and identified a role of ferroptosis in oligodendrocyte progenitor cell death and myelin injury after cerebral *** analysis suggested that perilipin-2(PLIN2)was involved in oligodendrocyte progenitor cell ***2 is a lipid storage protein and a marker of hypoxia.sensitive lipid droplet *** further investigation,we established a mouse model of cerebral ischemia/*** found significant myelin damage after cerebral ischemia,as well as oligodendrocyte progenitor cell death and increased lipid peroxidation levels around the infarct *** ferroptosis inhibitor,ferrostatin-1,rescued oligodendrocyte progenitor cell death and subsequent myelin *** also found increased PLIN2 levels in the peri-infarct area that co-localized with oligodendrocyte progenitor ***2 knockdown rescued demyelination and improved neurological *** findings suggest that targeting PLIN2 to regulate oligodendrocyte progenitor cell ferroptosis may be a potential therapeutic strategy for rescuing myelin damage after cerebral ischemia.

关键词： bioinformatics bulk RNA sequencing ferroptosis ischemic stroke myelin injury oligodendrocyte progenitor cell perilipin-2 single-cell RNA sequencing

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Based on non-targeted metabolomics for differential components screening of Rosae Chinensis Flos and Rosae Rugosae Flos and their quality evaluation

引用

Traditional Medicine Research 2025年第2期10卷 1-15页

作者： Xu Liang Ni-Hui Zhang Zhi-Lai Zhan Guang-lu Chang Yan Gao xia.Li Wen-Yuan Gao School of Pharmaceutical Science and Technology Faculty of MedicineTianjin UniversityTianjin 300193China State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs China Academy of Chinese Medical SciencesBeijing 100700China Key Laboratory of Modern Chinese Medicine Resources Research Enterprises Tianjin 300402China

Background:Rosa chinensis *** Rosa rugosa *** not only of ornamental value,but also edible flowers and the flower buds have been listed in the Chinese Pharmacopoeia as traditional *** two plants have some differences in efficacy,but the flower buds are easily confused for similar *** addition,large-scale cultivation of ornamental rose flowers may lead to a decrease in the effective components of medicinal ***,it is necessary to study the chemical composition and make quality evaluation of Rosae Chinensis Flos(Yueji)and Rosae Rugosae Flos(Meigui).Methods:In this study,40 batches of samples including Meigui and Yueji from different regions in China were collected to establish high-performance liquid chromatography ***,the fingerprints data was analyzed using principal component analysis,hierarchical cluster analysis,and partial least squares discriminant analysis analysis chemometrics to obtain information on intergroup differences,and non-targeted metabolomic techniques were applied to identify and compare chemical compositions of samples which were chosen from groups with large *** compounds were screened by orthogonal partial least-squares discriminant analysis and S-plot,and finally multi-component quantification was performed to comprehensively evaluate the quality of Yueji and ***:The similarity between the fingerprints of 40 batches roses and the reference print R was 0.73 to 0.93,indicating that there were similarities and differences between the *** principal component analysis and hierarchical cluster analysis of fingerprints data,the samples from different origins and varieties were intuitively divided into four *** least-squares discriminant analysis analysis showed that Meigui and Yueji cluster into two categories and the model was reliable.A total of 89 compounds were identified by high resolution mass spectrometry,mainly were flavonoids and flavon

关键词： Rosa chinensis Jacq. Rosa rugosa Thunb. metabolomics chemometrics multiple component quantification quality evaluation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Geometric Phases for Mixed States in Trapped Ions

引用

Communications in Theoretical Physics 2006年第3X期46卷 423-428页

作者： lu Hong-xia Department of Physics and Electronics Huaiyin Teachers College Huaian 213001 China

The generalization of geometric phase from the pure states to the mixed states may have potential applications in constructing geometric quantum gates. We here investigate the mixed state geometric phases and visibilities of the trapped ion system in both non-degenerate and degenerate cases. In the proposed quantum system, the geometric phases are determined by the evolution time, the initial states of trapped ions, and the initial states of photons. Moreover, special periods are gained under which the geometric phases do not change with the initial states changing of photon parts in both non-degenerate and degenerate cases. The high detection efficiency in the ion trap system implies that the mixed state geometric phases proposed here can be easily tested.

关键词： geometric phase mixed state trapped ions

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

First-principles insight into the entanglements between superionic diffusion and Li/Al antisite in Al-doped Li1+xAlxGe2–x(PO4)3(LAGP)

引用

Science China(Technological Sciences) 2020年第9期63卷 1787-1794页

作者： JIANG ChangKun lu xia.CAO DaPeng State Key Laboratory of Organic-Inorganic Composites Beijing University of Chemical TechnologyBeijing100029China School of Materials Sun Yat-sen UniversityGuangzhou510006China

As an ion conductor, the Al-doped Li1+xAlxGe2-x(PO4)3(LAGP) demonstrates the superionic Li diffusion behavior, however,without the convinced verifications. In this context, the density functional theory(DFT) calculations are employed to clarify the structural origin of the fast Li ion migration kinetics in LAGP solid electrolytes. The calculated results show that doping of Al leads to an emerging high-energy 36 f Li site, which plays an important role in promoting the Li diffusion and can largely lower the Li ion diffusion energy barrier. Moreover, the Li/Al antisite defect is investigated firstly, with which the Li ions are excited to occupy a relatively high energy site in LAGP. The obvious local structural distortion by Li/Al antisite results in the coordination change upon Li diffusion(lattice field distortion), which facilitates the Li diffusion significantly and is probably the main reason to account for the superionic diffusion phenomenon. Therefore, the occupation of Li at high-energy sites should be an effective method to establish the fast Li diffusion, which implies a rewarding avenue to build better Li-ion batteries.

关键词： Li1+xAlxGe2–x(PO4)3(LAGP) Li/Al antisite superionic conductor first-principles calculations Li ion batteries

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Stahel-Donoho kernel estimation for fixed design nonparametric regression models

引用

Science China Mathematics 2006年第12期49卷 1879-1896页

作者： LIN lu CUI xia School of Mathematics and System Sciences Shandong UniversityJi'nan 250100China School of Mathematics and System SciencesShandong UniversityJi'nan 250100China

This paper reports a robust kernel estimation for fixed design nonparametric regression models.A Stahel-Donoho kernel estimation is introduced,in which the weight functions depend on both the depths of data and the distances between the design points and the estimation *** on a local approximation,a computational technique is given to approximate to the incomputable depths of the *** a result the new estimator is computationally *** proposed estimator attains a high breakdown point and has perfect asymptotic behaviors such as the asymptotic normality and convergence in the mean squared *** the depth-weighted estimator for parametric regression models,this depth-weighted nonparametric estimator has a simple variance structure and then we can compare its efficiency with the original *** simulations show that the new method can smooth the regression estimation and achieve some desirable balances between robustness and efficiency.

关键词： nonparametric regression,kernel estimation,statistical depth,robustness.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Boundedness for commutators of Bochner-Riesz operators below a critical index

引用

Science China Mathematics 2007年第6期50卷 801-813页

作者： Shan-zhen lu xia.xia School of Mathentical Sciences Beijing Normal UniversityBeijing 100875China

In this paper, the authors obtain a necessary and sufficient condition for the LP bound-edness of commutators generated by Bochner-Riesz operators below a critical index and Lipschitz functions in two dimensional case... 详细信息

关键词： commutator Bochner-Riesz operators Lipschitz functions 42B15

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

New insights into mercury removal mechanism on CeO2- based catalysts： A first-principles study

引用

Frontiers of Environmental Science & Engineering 2018年第2期12卷 107-115页

作者： Ling Li Yu He xia.lu Forestry College Guizhou University Guiyang 550025 China Key Laboratory of High-Temperature and High-Pressure Study of the Earth's Interior Institute of Geochemistry Chinese Academy of Sciences Guiyang 550081 China State Key Laboratory of Organic-Inorganic Composites Beijing Advanced Innovation Center for Soft MatterScience and Engineering College of Energy Beijing University of Chemical Engineering Beijing 100029 China

First-principles calculanons were performed to investigate the mechamsm of Hg0 adsorpnon and oxidation on CeO2（111）. Surface oxygen acnvated by the reducnon of Ce to Ce a vlta to Hg~ adsorption and oxidation processes. Hg0 was fully oxidized by the surface lattice oxygen on CeO2（111）, without using any other oxidizing agents. HCI could dissociate and react with the Hg adatom on CeO2（111） to form adsorbed Hg CI or CI-Hg-Cl groups, which promoted the desorption of oxidized Hg and prevented CeO2 catalyst deactivation. In contrast, O-H and H-O-H groups formed during HC1 adsorption consumed the active surface oxygen and prohibited Hg oxidation. The consumed surface oxygen was replenished by adding O2 into the flue gas. We proposed that oxidized Hg desorption and maintenance of sufficient active surface oxygen were the rate-determining steps of Hg0 removal on CeO2-based catalysts. We believe that our thorough understanding and new insights into the mechanism of the Hg0 removal process will help provide guidelines for developing novel CeO2-based catalysts and enhance the Hg removal efficiency.

关键词： Elemental mercury removal Surface adsorption Ceria First-principles calculations

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Investigation of system structure and information processing mechanism for cognitive skywave over-the-horizon radar

引用

Journal of Systems Engineering and Electronics 2016年第4期27卷 797-806页

作者： xia.Wu Jianwen Chen Kun lu Key Laboratory for Radar Application Engineering Wuhan Institute of RadarWuhan 430019China Nanjing Research Institute of Electronics Technology Nanjing 210039China

Based on the cognitive radar concept and the basic connotation of cognitive skywave over-the-horizon radar（SWOTHR）, the system structure and information processingmechanism about cognitive SWOTHR are researched. Amongthem, the hybrid network system architecture which is thedistributed configuration combining with the centralized cognition and its soft/hardware framework with the sense-detectionintegration are proposed, and the information processing framebased on the lens principle and its information processing flowwith receive-transmit joint adaption are designed, which buildand parse the work law for cognition and its self feedback adjustment with the lens focus model and five stages informationprocessing sequence. After that, the system simulation andthe performance analysis and comparison are provided, whichinitially proves the rationality and advantages of the proposedideas. Finally, four important development ideas of futureSWOTHR toward ＂high frequency intelligence information processing system＂ are discussed, which are scene information fusion, dynamic reconfigurable system, hierarchical and modulardesign, and sustainable development. Then the conclusion thatthe cognitive SWOTHR can cause the performance improvement is gotten.

关键词： cognitive radar skywave over-the-horizon radar system structure intelligence information processing information fusion target detection

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Nuclei-rich galvanizing strategy for suppressing zinc dendrite growth

引用

Rare Metals 2024年第8期43卷 4016-4018页

作者： Hai-xia.Wu Kai-lu Guo College of Chemistry and Chemical Engineering Henan Key Laboratory of Function-Oriented Porous MaterialsLuoyang Normal UniversityLuoyang 471934China

The uncontrolled growth of zinc dendrites on zinc anode hinders the application of zinc ion *** solve this problem,lu's group proposed a nuclei-rich galvanizing strategy for suppressing the zinc dendrite *** allows the nuclei-rich zinc electrode to cycle steadily for1200 h and have a high Coulombic efficiency of 99.7%at15 mA·cm^(-2)with a deposited amount of 10 mAh·cm^(-2).Moreover,the Zn-MnO_(2) battery with a low N/P ratio of 1.9exhibited sustained cycling life.

关键词： cycling sustained battery

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Zeolite polymer membrane as protective interface for Mg battery

引用

Rare Metals 2024年第9期43卷 4636-4638页

作者： Hai-xia.Wu Kai-lu Guo College of Chemistry and Chemical Engineering Henan Key Laboratory of Function-Oriented Porous MaterialsLuoyang Normal UniversityLuoyang 471934China

Excessive electrolyte decomposition seriously determines the performance of high-voltage Mg batteries. In Nazar's work, the strategy using a zeolite polymer membrane as a protective interface was proposed to restrain the electrolyte decomposition. This strategy could boost Mg plating/stripping performance up to 6000 h in zeolite/Mg|zeolite/Mg symmetric cells and 91%capacity retention in zeolite/Mg||Mo_(3)S_(4)battery after 200 *** storage devices have been intensively explored because of their important roles in our daily lives [1D3].

关键词： zeolite interface electrolyte

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：