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Exploring the mechanism of neural-function reconstruction by reinnervated nerves in targeted muscles

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Journal of Zhejiang University-Science C(Computers and Electronics) 2014年第10期15卷 813-820页

作者： Hui ZHOU Lin YANG Feng-xia WU Jian-ping HUANG Liang-qing ZHANG ying-jian YANG Guang-lin LI Institute of Biomedical and Health Engineering Shenzhen Institutes of Advanced TechnologyChinese Academy of Sciences Department of Rehabilitation Medicine Nanshan Hospital Affiliated to Guangdong Medical College Sino-Dutch Biomedical and Information Engineering School of Northeastern University

A lack of myoelectric sources after limb amputation is a critical challenge in the control of multifunctional motorized prostheses. To reconstruct myoelectric sources physiologically related to lost limbs, a newly proposed neural-function construc- tion method, targeted muscle reinnervation （TMR）, appears promising. Recent advances in the TMR technique suggest that TMR could provide additional motor command information for the control of multifimctional myoelectric prostheses. However, little is known about the nature of the physiological functional recovery of the reinnervated muscles. More understanding of the under- lying mechanism of TMR could help us fine tune the technique to maximize its capability to achieve a much higher performance in the control of multifunctional prostheses. In this study, rats were used as an animal model for TMR surgery involving transferring a median nerve into the pectoralis major, which served as the target muscle. Intramuscular myoelectric signals reconstructed following TMR were recorded by implanted wire electrodes and analyzed to explore the nature of the neural-fimction recon- struction achieved by reinnervation of targeted muscles. Our results showed that the active myoelectric signal reconstructed in the targeted muscle was acquired one week after TMR surgery, and its amplitude gradually became stronger over time. These pre- liminary results from rats may serve as a basis for exploring the mechanism of neural-function reconstruction by the TMR tech- nique in human subjects.

关键词： Neural function reconstruction Targeted muscle reinnervation Intramuscular myoelectric signal Myoelectri^prostheses /

The Principle of Production and a Critique of Metaphysics： From the Perspective of Theory of Baudrillard

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Frontiers of Philosophy in China 2014年第2期9卷 181-193页

作者： xia ying Department of Philosophy Tsinghua University Beijing 100084 China

In this article, I discuss Baudrillard＇s critique of metaphysics based on his work The Mirror of Production, in which he stresses the principle of production--i.e., dichotomy and derivation. In the development of classical German philosophy, the principle of production was speculatively established, first as Descartes＇ cogito, then as Fichte＇s Tathandlung, and finally as Hegel＇s labor, and grew to be a major principle of modem metaphysics. At the article＇s conclusion, the meaning of Symbolic Exchange--Baudrillard＇s utopian condition lying beyond the principle of production--will be discussed.

关键词： Baudrillard metaphysics production symbolic exchange,reciprocal

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InSe单层中点缺陷的第一性原理研究

原子与分子物理学报 2025年第6期42卷 167-173页

作者：何诗颖谢瑞恬刘娟邹代峰赵宇清许英廖雨洁湖南科技大学物理与电子科学学院湘潭411201 智能传感器与新型传感器材料湖南省重点实验室湘潭411201 山西大学化学化工学院太原030006 武汉大学动力与机械学院武汉430072

InSe是Ⅲ-Ⅵ族化合物中的主要成员,由于其具有优异的电学性能,在太阳能电池、固体电池组等领域受到广泛的关注.光电材料及器件的优良特性由电子结构决定,而Ⅲ-Ⅵ族化合物中的点缺陷对电子结构具有重要的调控,且单层InSe中点缺陷的Perdew... 详细信息

InSe是Ⅲ-Ⅵ族化合物中的主要成员,由于其具有优异的电学性能,在太阳能电池、固体电池组等领域受到广泛的关注.光电材料及器件的优良特性由电子结构决定,而Ⅲ-Ⅵ族化合物中的点缺陷对电子结构具有重要的调控,且单层InSe中点缺陷的Perdew-Burke-Ernzerhof(PBE)和Heyd-Scuseria-Ernzerhof(HSE)对比研究尚且缺乏.本文基于密度泛函理论的第一性原理计算,对单层InSe的硒空位、铟空位、溴替代硒、硫替代硒、碲替代硒、镓替代铟、锡替代铟和铊替代铟的缺陷形成能和稳定性进行了研究.结果表明:在缺铟和富铟条件下,硫替代硒和镓替代铟的缺陷形成能低且可以有效的降低体系总能,提高体系的稳定性.溴替代硒具有较小的缺陷形成能,但较大的体系总能表明溴替代硒的缺陷体系不稳定.在缺铟条件下易形成铊替代铟缺陷;在富铟条件下易形成碲替代硒缺陷.上述研究结果有助于理解点缺陷对Ⅲ-Ⅵ族化合物稳定性的影响,同时也为未来实验上设计基于InSe的高效的光电子器件提供理论依据.

关键词：单层InSe 稳定性形成能点缺陷

A delayed reaction–diffusion viral infection model with nonlinear incidences and cell-to-cell transmission

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International Journal of Biomathematics 2021年第8期14卷 305-342页

作者： qing Ge xia Wang Libin Rong School of Mathematics and Statistics XinyangNormal UniversityXinyang 464000P.R.China Department of Mathematics University of FloridaGainesvilleFL 32611USA

In this paper,we propose a reaction–diffusion viral infection model with nonlinear incidences,cell-to-cell transmission,and a time *** impose the homogeneous Neumann boundary *** the case where the domain is bounded,we first study the *** we analyze the local stability of homogeneous steady *** establish a threshold dynamics which is completely characterized by the basic reproduction *** the case where the domain is the whole Euclidean space,we consider the existence of traveling wave solutions by using the cross-iteration method and Schauder’s fixed point ***,we study how the speed of spread in space affects the spread of cells and *** obtain the existence of the wave speed,which is dependent on the diffusion coefficient.

关键词： Reaction-diffusion equation cell-to-cell transmission absorption effect time delay traveling wave solutions

Expression of midkine and its clinical significance in esophageal squamous cell carcinoma

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World Journal of Gastroenterology 2006年第13期12卷 2006-2010页

作者： ying-Jia Ren qing-Yun Zhang Department of Immunology The School of Ontology Peking University Beijing Institute for Cancer Research Beijing 100036 China Department of Medical Laboratory Beijing Cancer Hospital Beijing 100036 China

AIM： To investigate the expression of midkine in eso- phageal squamous cell carcinoma （ESCC） and analyze its relationship with clinicopathological features. METHODS： RT-PCR and immunocytochemical staining were used to detect the expression of midkine mRNA and protein in EC109 cells, respectively. Then the expression of midkine in 66 cases of ESCC samples were detected by immunohistochemistry using monoclonal antibodies against human midkine. RESULTS： Midkine was expressed in EC109 cell by RT- PCR and imrnunocytochemistry. The immunoreactivity was detected in 56.1% （37/66） of the ESCC samples. The expression of midkine was found in cytoplasm of tumor cells. Notably, the intensity of midkine was stronger at the area abundant in vessels and the invading border of the tumors. Midkine was more intensely expressed in well differentiated tumors （76.9 %） than in moderately and poorly differentiated tumors （43.1% and 41.2%, respectively）（P〈0.05）. There was no statistically significant correlation between midkine expression and gender, age, clinical stage, lymph node metastasis or survival in ESCC. CONCLUSION： IVlidkine is overexpressed in ESCC. It may play a role in tumor angiogenesis and invasion. The expression of midkine is correlated with tumor cell differentiation in ESCC. The more poorly tumor cells differentiate, the weaker midkine expresses.

关键词： Midkine Esophageal squamous cell carcinoma Expression

Dynamic ModeⅡfracture behavior of rocks under hydrostatic pressure using the short core in compression(SCC)method

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International Journal of Mining Science and Technology 2021年第5期31卷 927-937页

作者： Wei Yao ying XuChonglang Wang Kaiwen xia Mikko Hokka State Key Laboratory of Hydraulic Engineering Simulation and Safety School of Civil EngineeringTianjin UniversityTianjin 300072China State Key Laboratory of Explosion Science and Technology Beijing Institute of TechnologyBeijing 100081China Engineering Materials Science Faculty of Engineering and Natural SciencesTampere University(TAU)POB 589FI-33014 TampereFinland Department of Civil&Mineral Engineering University of TorontoTorontoON M5S 1A4Canada

The shear failure of rocks under both a static triaxial stress and a dynamic disturbance is common in deep underground engineering and it is therefore essential for the design of underground engineering to quantitively estimate the dynamic ModeⅡfracture toughness KⅡCof rocks under a triaxial stress ***,the method for determining the dynamic KⅡCof rocks under a triaxial stress has not been developed *** an optimal sample preparation,the short core in compression(SCC)method was designed and verified in this study to measure the dynamic KⅡCof Fangshan marble(FM)subjected to different hydrostatic pressures through a triaxial dynamic testing *** formula for calculating the dynamic KⅡCof the rock SCC specimen under hydrostatic pressures was obtained by using the finite element method in combination with secondary *** experimental results indicate that the failure mode of the rock SCC specimen under a hydrostatic pressure is the shear fracture and the KⅡCof FM increases as the loading *** addition,at a given loading rate the dynamic rock KⅡCis barely affected by hydrostatic *** important observation is that the dynamic fracture energy of FM enhances with loading rates and hydrostatic pressures.

关键词： Loading rate Finite element method ModeⅡfracture toughness Fangshan marble Hydrostatic pressure Short core in compression

Gauge Covariance and Momentum Space Asymptotically Non-logarithmic Total Derivatives

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Communications in Theoretical Physics 2008年第2期49卷 431-434页

作者： LU Qin ZHANG ying WANG qing Department of Physics Tsinghua University Beijing 100084 China

We focus on a new gauge symmetry keeping regularization scheme for momentum integration and point out that dropping out momentum space asymptotic non-logarithmic total derivative divergent integrations in quantum fiel... 详细信息

关键词： gauge covariance momentum integration total derivative

Syntheses, Structures, and Blue Luminescent Properties of 2,6-Bis-(benzimidazolyl) Pyridine and Its Mercury Complex

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Chemical Research in Chinese Universities 2007年第2期23卷 159-162页

作者： LIU xiao-ming MU xiao-yue xia Hong SU qing YE Ling CHEN Chao GAO Wei MU ying Key Laboratory for Supramolecular Structure and Materials of Ministry of Education College of Chemistry Jilin University Changchun 130012 P. R. China State Key Laboratory of Inorganic Synthesis and Preparative Chemistry College of Chemistry Jilin University Changchun 130012 P. R. China

A novel blue luminescent mercury （ Ⅱ ） complex of 2,6-bis （benzimidazolyl） pyridine （L） was synthesized. In solid state, this complex has the formula [Hg（L）Cl2] · 2DMF（1）. The molecular structures of both the ligand and the complex were determined by using tingle-crystal X-ray diffraction. Crystallographic studies of the mercury （ Ⅱ） complex reveal that the complex possesses a five-coordinated geometry that can be best described as a distorted trigonal-bipyramidal. The luminescent properties of ligand L and complex 1 both in solution and in solid state were also studied.

关键词： 2,6-Bis (benzimidazolyl) pyridine Mercury Crystal structure Blue luminescence

Improved Teaching-Learning-Based Optimization Algorithm for Modeling NOX Emissions of a Boiler

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Computer Modeling in Engineering & Sciences 2018年第10期117卷 29-57页

作者： xia Li Peifeng Niu Jianping Liu qing Liu School of Electrical Engineering Yanshan UniversityQinhuangdao066004China School of Mathematics and Information Science&Technology Hebei Normal University of Science and TechnologyQinhuangdao066004China

An improved teaching-learning-based optimization(I-TLBO)algorithm is proposed to adjust the parameters of extreme learning machine with parallel layer perception(PELM),and a well-generalized I-TLBO-PELM model is obtained to build the model of NOX emissions of a *** the I-TLBO algorithm,there are four major ***,a quantum initialized population by using the qubits on Bloch sphere replaces a randomly initialized ***,two kinds of angles in Bloch sphere are generated by using cube chaos ***,an adaptive control parameter is added into the teacher phase to speed up the convergent *** then,according to actual teaching-learning phenomenon of a classroom,students learn some knowledge not only by their teacher and classmates,but also by ***,a self-study strategy by using Gauss mutation is introduced after the learning phase to improve the exploration ***,we test the performance of the I-TLBO-PELM *** experiment results show that the proposed model has better regression precision and generalization ability than eight other models.

关键词： Bloch sphere qubits self-learning improved teaching-learning-based optimization(I-TLBO)algorithm