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Frontiers of Architectural Research 2019年第3期8卷 348-358页

作者： Jian Jiao qiuling xia Fei Shi School of Architecture Southeast UniversityNanjingChina Jiangsu Southeast University Testing and Inspection Technology Company NanjingChina

Detailed survey and inspection of the structure of the lecture hall of the Anyuan Miners’Club were conducted during a restoration *** inspection measures were used to assess the physical and mechanical conditions of the *** brick and wood structures of the building were tested,the overall bearing capacity was calculated,and a safety appraisal was conducted in accordance with the codes and standards of the existing *** results provide architects and construction engineers with reliable data to develop a preservation plan and ensure the safety of the heritage building.

关键词： Modern architectural heritage Brick-timber structure In situ assessment Nondestructive inspection Safety appraisal

Overview of flowline bundle technology from concept selection to offshore installation

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Engineering Sciences 2013年第4期11卷 10-16页

作者： Song Ruxin xia qiuling DMAR Engineering Inc.

Flowline bundle system consisting of carrier pipe,sleeve pipe and internal flowlines offers innovative solution for the infield transportation of oil and gas. Due to its features,flowline bundle offers a couple of advantages over conventional flowline in particular for cases where multi-flowlines and high thermal performance is of great interest. The main benefits and advantages of such system include excellent thermal performance to prevent wax formation and hydrates,multiple bundled flowlines,mechanical and corrosion protection,potential reuse, etc. With the developments of offshore oil and gas industries,more and more hydrocarbon resources are being explored and discovered from shallow to deep water. Pipeline bundle system can be a smart solution for certain applications,which can be safe and cost effective solution. The objective of this paper is to overview pipeline bundle technology,outline detailed engineering design issue and procedure. Focus is given to its potential application in offshore for infield transportation. Engineering design principles and procedures for pipeline bundle system are highlighted. Construction methods of flowline bundle onshore are reviewed. Offshore towing and installation of pipeline bundle procedure is outlined.

关键词： offshore pipelines flowlines bundles deepwater design installation

结晶造粒流化床技术在浓盐水软化除硬处理中的设计应用

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广东化工 2023年第2期50卷 30-32,6页

作者：胡舒雯谢长血夏秋玲金梅北京中电加美环保科技有限公司北京100083

石油化工企业脱盐水用水量大,出于节水的考虑,需要将浓水进行回收处理,为了防止回收处理的浓缩过程结垢,保证浓水反渗透正常运行,在一项石化企业的脱盐水处理项目上,采用结晶造粒流化床技术对反渗透浓盐水进行化学除硬预处理,处理后的... 详细信息

石油化工企业脱盐水用水量大,出于节水的考虑,需要将浓水进行回收处理,为了防止回收处理的浓缩过程结垢,保证浓水反渗透正常运行,在一项石化企业的脱盐水处理项目上,采用结晶造粒流化床技术对反渗透浓盐水进行化学除硬预处理,处理后的浓盐水硬度约为200 mg/L,收到了良好的应用效果。

关键词：结晶造粒流化床脱盐水反渗透浓盐水除硬

国内外油田本质安全设计(ISD)差异性研究及启示

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石油化工安全环保技术 2022年第1期38卷 28-31,I0002页

作者：夏秋玲郭振东孙锐卢亚萍中国石油工程建设有限公司北京设计分公司北京100084

目前国内本质安全设计(ISD)的项目应用案例较少,因此对本质安全设计(ISD)的内容、开展时机、与其他风险识别方法的关系和基本原则进行了梳理,明确了本站安全分析开展的流程和各阶段相应的内容。海上平台具有工艺设备集成度高、作业空间... 详细信息

目前国内本质安全设计(ISD)的项目应用案例较少,因此对本质安全设计(ISD)的内容、开展时机、与其他风险识别方法的关系和基本原则进行了梳理,明确了本站安全分析开展的流程和各阶段相应的内容。海上平台具有工艺设备集成度高、作业空间有限、环境条件苛刻、事故危害大等特点。一旦发生重大事故,除财产、环境和公司声誉的巨大损失外,现场控制难,人员逃生难度大。使用本质安全设计的原理结合中东地区某海工项目实例,列举了本质安全设计在项目开展过程中的重要结论,并与国内海工项目(未实行本质安全设计)进行了差异性对比研究,提出了目前国内外海洋工程项目HSE方面一些不同的做法,对后续中东地区海工项目的风险评价和项目费用控制有指导意义。

关键词：本质安全设计风险识别风险评估重大事故危害头脑风暴

Drug target discovery by magnetic nanoparticles coupled mass spectrometry

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Journal of Pharmaceutical Analysis 2021年第1期11卷 122-127页

作者： Dandan xia Baoling Liu xiaowei Xu Ya Ding qiuling Zheng Department of Pharmaceutical Analysis School of PharmacyChina Pharmaceutical UniversityNanjing210009China State Key Laboratory of Natural Medicines China Pharmaceutical UniversityNanjing210009China Key Laboratory of Drug Metabolism and Pharmacokinetics China Pharmaceutical UniversityNanjing210009China

Drug target discovery is the basis of drug *** elucidates the cause of disease and the mechanism of drug action,which is the essential of drug *** discovery performed in biological systems is complicated as proteins are in low abundance and endogenous compounds may interfere with drug ***,methods to track drug-target interactions in biological matrices are urgently *** this work,a Fe_(3)O_(4) nanoparticle-based approach was developed for drug-target screening in biofluids.A known ligand-protein complex was selected as a principle-to-proof example to validate the *** incubation in cell lysates,ligand-modified Fe_(3)O_(4) nanoparticles bound to the target protein and formed complexes that were separated from the lysates by a magnet for further *** large surface-to-volume ratio of the nanoparticles provides more active sites for the modification of chemical *** enhances the opportunity for ligand-protein interactions,which is beneficial for capturing target proteins,especially for those with low ***,a one-step magnetic separation simplifies the pre-processing of ligand-protein complexes,so it effectively reduces the endogenous ***,the present nanoparticle-based approach has the potential to be used for drug target screening in biological systems.

关键词： Drug-target discovery Nanoparticle Mass spectrometry

基层医疗卫生机构新型冠状病毒肺炎疫情防控常态化工作存在的问题和对策建议

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中国全科医学 2020年第35期23卷 4407-4411页

作者：张冬莹姚弥杨信林恺夏秋玲刘明圆郭发刚郑劲平钟南山广州医科大学附属第一医院广州呼吸健康研究院国家呼吸系统疾病临床医学研究中心广东省广州市510120 北京大学医学部全科医学系北京100191 汕头大学医学院第一附属医院广东省汕头市515041 广东省广州市番禺区东环街社区卫生服务中心 511400 广东省广州市番禺区南村镇社区卫生服务中心 511442 留坝县玉皇庙镇中心卫生院陕西省汉中市724103

在新型冠状病毒肺炎疫情防控中,基层医疗卫生机构对社区疫情防控和防疫关口前移发挥重要作用,是外防输入、内防扩散的最有效防线。在面对当下乃至未来较长一段时间内存在的新型冠状病毒感染局部暴发或区域性流行的情况下,基层医疗卫生... 详细信息

在新型冠状病毒肺炎疫情防控中,基层医疗卫生机构对社区疫情防控和防疫关口前移发挥重要作用,是外防输入、内防扩散的最有效防线。在面对当下乃至未来较长一段时间内存在的新型冠状病毒感染局部暴发或区域性流行的情况下,基层医疗卫生机构需要把防疫工作常态化,及时补足重大疫情防控中的短板,包括环境建设欠规范、应急物资储备不足、制度建设流于形式、基层医疗卫生应急能力不足等。建议改善基层医疗卫生机构场地环境、完善制度、提升基层应急能力,重视基层医疗卫生工作者的劳动价值并建立有效激励措施,以利于基层医疗卫生机构持久战疫。

关键词：基层医疗卫生机构新型冠状病毒新型冠状病毒肺炎疫情防控常态化专家建议

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河池某污染场地重金属污染特征与生态风险评价

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广东化工 2022年第13期49卷 143-147,151页

作者：夏秋玲黎承波莫莉萍林清赵银军南宁师范大学地理科学与规划学院广西南宁530001 广西研易达科技有限公司广西南宁530022 南宁师范大学环境与生命科学学院广西南宁530001

以河池某公司疑似污染场地为调查对象,依据场地环境调查技术导则(HJ 25.1-2014)等有关国家环境保护标准,分析该场地不同区域土壤和地下水典型污染物的污染特征。结果表明,场地内土壤均未受到重金属元素砷、镉、铜、铅、镍的污染,其潜在... 详细信息

以河池某公司疑似污染场地为调查对象,依据场地环境调查技术导则(HJ 25.1-2014)等有关国家环境保护标准,分析该场地不同区域土壤和地下水典型污染物的污染特征。结果表明,场地内土壤均未受到重金属元素砷、镉、铜、铅、镍的污染,其潜在生态风险级别为轻微。场地内地下水存在镉、铜、锌、镍、锰和硫酸根超标现象。场地内地下水重金属污染可能是场地内黑色炭质泥岩中的黄铁矿氧化导致土壤和水体酸化,黑色炭质泥岩中的重金属在酸性条件下经雨水冲刷、淋滤作用下渗水迁移导致,具体情况还须对场地内岩石进行重金属污染调查。

关键词：土壤重金属地下水污染风险评价黑色炭质泥岩

Hydrogen selenide,a vital metabolite of sodium selenite,uncouples the sulfilimine bond and promotes the reversal of liver fibrosis

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Science China(Life Sciences) 2021年第3期64卷 443-451页

作者： Dongrui Luan Zengteng Zhao Dandan xia qiuling Zheng xiaonan Gao Kehua Xu Bo Tang College of Chemistry Chemical Engineering and Materials ScienceCollaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of ShandongKey Laboratory of Molecular and Nano ProbesMinistry of EducationInstitute of Molecular and Nano ScienceShandong Normal UniversityJinan 250014China Department of Pharmaceutical Analysis School of PharmacyState Key Laboratory of Natural MedicinesChina Pharmaceutical UniversityNanjing 210009China

Sodium selenite has alleviating effects on liver fibrosis;however,its therapeutic molecular mechanism remains ***,hydrogen selenide,a major metabolite of Na_(2)SeO_(3),was tested to uncouple the sulfilimine bond in collagen IV,the biomarker of liver fibrosis.A mouse model of liver fibrosis was constructed via a CCl_(4)-induced method,followed by the administration of 0.2 mg kg−1 Na_(2)SeO_(3)via gavage three times per week for 4 *** in H2Se,NADPH,and H_(2)O_(2)levels were monitored in real time by using NIR-H2Se,DCI-MQ-NADPH,and H_(2)O_(2)probes in vivo,respectively.H_(2)Se continuously accumulated in the liver throughout the Na_(2)SeO_(3)treatment period,but the levels of NADPH and H_(2)O_(2)*** expression of collagen IV was analyzed through Western blot and liquid chromatography-mass *** confirmed that the sulfilimine bond of collagen IV in the fibrotic mouse livers could be broken by H2Se with the Na_(2)SeO_(3)***,the therapeutic effect of Na_(2)SeO_(3)on liver fibrosis could be mainly attributed to H_(2)Se that uncoupled the sulfilimine bond to induce collagen IV *** study provided a reasonable explanation for the molecular mechanism of the in vivo function of Na_(2)SeO_(3)and the prevention of liver fibrosis by administering inorganic selenium.

关键词： hydrogen selenide sodium selenite sulfilimine bond liver fibrosis reversal collagen IV

Effect of thickness on infrared optical property of VO2 film deposited by magnetron sputtering

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Science China(Technological Sciences) 2020年第8期63卷 1591-1598页

作者： YANG ZhenHuai YANG qiuling YANG Lei DAI Bing xia Fei WANG Peng GUO Shuai GAO Gang XU LiangGe ZHANG YuMin ZHU JiaQi National Key Laboratory of Science and Technology on Advanced Composites in Special Environments Harbin Institute of TechnologyHarbin 150080China Key Laboratory of Micro-systems and Micro-structures Manufacturing Ministry of EducationHarbin 150080China Center of Analysis Measurement Harbin Institute of TechnologyHarbin 150080China

A series of VO2 films with different thicknesses(from about 25 nm to 250 nm)were prepared on sapphire substrates by radio frequency magnetron *** deposition times varied from 15 min to 150 *** metal to insulator transitions(MIT)of the films were *** optical transmittance of the films to infrared light(with a wavelength of 4.0μm)at room temperature(30℃)varied significantly with film thickness,ranging from 86.53%to 41.01%.The modulation property also changes with thickness,decreasing from 22.89%to 14.74%.The phase transition temperature remained approximately 70℃during heating,and approximately 53℃during cooling,despite a tenfold increase in the deposition time,and the resulting thickness of the *** spectroscopy of the films indicated that the intensities of the characteristic peaks corresponding to V2O5 increase with the increasing of film ***-dependent Raman spectroscopy indicated that the peaks corresponding to VO2 undergo reversible changes during heating and cooling of the films,while the peaks corresponding to V2O5 remain unchanged *** control of the V2O5 content of the films(by varying the duration of the deposition process)allows control over their transmittance and optical modulation properties without changes in the phase transition *** provides a new method of controlling the optical properties of these materials and shows promise for their potential applications in thermochromic windows.

关键词： Vanadium dioxide mid-infrared transmittance phase transition temperature magnetron sputtering

Ages, Trace Elements and Hf-Isotopic Compositions of Zircons from Claystones around the Permian-Triassic Boundary in the Zunyi Section, South China: Implications for Nature and Tectonic Setting of the Volcanism

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Journal of Earth Science 2015年第6期26卷 872-882页

作者： qiuling Gao Zhong-Qiang Chen Ning Zhang William L.Griffin Wenchen xia Guoqing Wang Tengfei Jiang Xuefei xia Suzanne Y.O'Reilly Exploration & Development Research Institute Zhongyuan Oilfield Company School of Earth Sciences China University of Geosciences Australian Research Council Centre of Excellence for Core to Crust Fluid Systems and GEMOC National Key Centre Department of Earth and Planetary Science Macquarie University State Key Laboratory of Biogeology and Environmental Geology China University of Geosciences Shandong Lunan Institute of Geo-Engineering Exploration Jianghan Oilfield Company

A growing body of evidence shows that volcanism near the Permian-Triassic boundary（PTB） may be crucial in triggering the Permian–Triassic（P–Tr） mass extinction. Thus, the ash beds near the PTB in South China may carry information on this event. Three volcanic ash layers, altered to clay, outcropped in the PTB beds in Zunyi Section, Guizhou Province, Southwest China. The U-Pb ages, trace elements, and Hf-isotope compositions of zircon grains from these three ash beds were analyzed using LA-ICPMS and LA-MC-ICPMS. The zircons are mainly magmatic in origin（241-279 Ma） except for two inherited/xenocrystic zircons（939 and 2 325 Ma）. The ages of these magmatic zircons indicate three episodes of magmatism which occurred around the MiddleLate Permian boundary（-261.5 Ma, MLPB）, the Wuchiapingian-Changhsingian boundary（-254.5 Ma, WCB）, and the PTB（-250.5 Ma）, respectively. The first two episodes of magmatism near the MLPB and WCB may be attributed to magmatic inheritance or re-deposition. All magmatic zircons share similar trace-element and Hf-isotope compositions. They have Y, Hf, Th and U contents and Nb/Ta ratios are typical of zircons from silicic calc-alkaline magmas. These zircons also exhibit enriched Hf-isotope compositions with _（εHf）（t） values of-11.4 to ＋0.2, which suggests that the three magmatic episodes involved melting of the continental crust. The more enriched Hf-isotope composition （_（εHf）（t）=-11.4--4.8） of Bed ZY13（-250.5 Ma） implies more input of ancient crustal material in the magma. Integration of the Hf-isotope and trace-element compositions of magmatic zircons suggest that these three episodes of magmatism may take place along the convergent continent margin in or near southwestern South China as a result of the closure of the Palaeo-Tethys Ocean.

关键词： Permian-Triassic boundary zircon trace elements Hf isotope silicic volcanism,convergent continental margin South China.