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妇宝当归胶对IVF反复种植失败患者冻融胚胎移植结局影响的初步研究

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中医临床研究 2020年第6期12卷 98-102页

作者：宋景艳孙振高杨文秀赵秀先崔文娜夏庆昌刘红根牟珍妮乔岩山东中医药大学第一临床医学院山东济南250014 山东中医药大学附属医院中西医结合生殖与遗传中心山东济南250011 山东中医药大学中医学院山东济南250011

目的:评价妇宝当归胶在改善反复种植失败患者妊娠结局中的应用价值。方法:本研究为前瞻性、开放性随机对照试验(Randomized Controlled Trial,RCT),59名反复种植失败(Recurrent Implantation Failure,RIF)患者皆行人工周期冻融胚胎移植(... 详细信息

目的:评价妇宝当归胶在改善反复种植失败患者妊娠结局中的应用价值。方法:本研究为前瞻性、开放性随机对照试验(Randomized Controlled Trial,RCT),59名反复种植失败(Recurrent Implantation Failure,RIF)患者皆行人工周期冻融胚胎移植(Frozen Embryo Transfer,FET),共分为两组,干预组采用人工周期配合妇宝当归胶进行内膜准备,对照组仅采用人工周期方案。统计学上采用独立样本T检验、Mann–Whitney U检验和Chi-square分析,P<0.05为差异有统计学意义。结果:中医证候积分比较,治疗组显著低于对照组(P<0.05);与对照组相比,干预组内膜转化日子宫内膜血管化指数(Vascularization Index,VI)(P=0.001)、血管血流指数(Vascularization Flow Index,VFI)(P=0.003)更高,差异具有统计学意义;两组白细胞介素17(Interleukin 17,IL-17)水平比较有显著性差异(P<0.01),治疗组低于对照组。同时,FET后干预,差异具有统计学意义41.4%(12/29)vs 16.7%(5/30);31%(9/29)vs 10%(3/30);31%(9/29)vs 6.7%(2/30)。结论:妇宝当归胶可通过改善子宫内膜容受性(Endometrial Receptivity,ER),增加RIF患者持续妊娠率、临床妊娠率及阳性妊娠率,改善其IVF/ICSI妊娠结局,其机制可能与改善子宫内膜血流,调整子宫内膜局部免疫等功能有关。由于本次研究为开放性预试验,受样本量和盲法的限制,结果可能存在一定程度偏倚,因此其疗效仍需要更多的多中心、大样本、双盲RCT验证。

关键词：妇宝当归胶反复种植失败子宫内膜容受性妊娠结局

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川西南井研地区灯影组断溶体形成机制与识别

断块油气田 2020年第2期27卷 193-197页

作者：李一超杨飞徐天鑫夏文豪王晴长江大学油气资源与勘探技术教育部重点实验室湖北武汉430100 长江大学地球物理与石油资源学院湖北武汉430100 长江大学地球科学学院湖北武汉430100

川西南井研地区震旦系灯影组地层经桐湾多幕升降运动,发生多期构造变形和岩溶作用,岩溶储层发育。经早寒武世兴凯地裂运动,灯影组内形成一系列层间断层,该系列断层沟通灯影组顶面不整合面,并以断层面发生溶蚀扩大。依据高精度三维地震... 详细信息

川西南井研地区震旦系灯影组地层经桐湾多幕升降运动,发生多期构造变形和岩溶作用,岩溶储层发育。经早寒武世兴凯地裂运动,灯影组内形成一系列层间断层,该系列断层沟通灯影组顶面不整合面,并以断层面发生溶蚀扩大。依据高精度三维地震资料解释,通过构造演化分析,明确了区内灯影组层间断层形成机制;经JS1井钻遇,结合正演模拟分析,借鉴塔河地区断溶体圈闭理论,提出了井研地区灯影组碳酸盐岩断溶体发育模式,明确了断溶体地震响应特征;利用地震多属性分析,结合剖面上的追踪与刻画,明确了断溶体展布特征,为有利区优选提供有力依据。

关键词：碳酸盐岩桐湾运动兴凯地裂运动断溶体正演模拟地震属性

机器人辅助腹腔镜与开腹肝切除术治疗肝脏疾病效果比较的Meta分析

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临床肝胆病杂志 2020年第8期36卷 1778-1782页

作者：张斌罗德彭方毅方程淦宇贺凯李波夏先明苏松西南医科大学附属医院肝胆外科四川泸州646000 井研县人民医院普通外科四川乐山613100

目的本研究旨在比较机器人辅助腹腔镜肝切除术(RALH)与开腹肝切除术(OH)对肝脏疾病的治疗效果与安全性。方法通过计算机全面检索Web of Science、PubMed、Cochrane Library、Embase、中国知网、中国生物医学文献、维普和万方数据库,筛... 详细信息

目的本研究旨在比较机器人辅助腹腔镜肝切除术(RALH)与开腹肝切除术(OH)对肝脏疾病的治疗效果与安全性。方法通过计算机全面检索Web of Science、PubMed、Cochrane Library、Embase、中国知网、中国生物医学文献、维普和万方数据库,筛选出比较RALH与OH治疗肝脏疾病的所有中英文文献,检索时间截至2020年2月。对纳入文献进行质量学评价后,采用Revman 5.1软件进行Meta分析。结果经筛选后共纳入7篇研究,包括754例患者,其中RALH组328例,OH组426例。Meta分析结果显示,与OH组相比,RALH的手术时间较长[均值(MD)=59.41,95%可信区间(95%CI):9.74~109.08,P=0.02];且输血率[相对危险度(RR)=2.24,95%CI:1.04~4.82,P=0.04]和肝门阻断率(RR=2.27,95%CI:1.37~3.75,P=0.001)较高;但住院时间(MD=-3.87,95%CI:-5.63^-2.12,P0.05)。结论在肝切除术中,RALH可以缩短住院时间并降低术后并发症,为肝脏微创切除及快速康复的实现创造了条件。

关键词：肝切除术腹腔镜检查机器人手术 Meta分析(主题)

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川南下古生界高演化页岩成熟度指标

断块油气田 2018年第1期25卷 43-47页

作者：史洪亮王同陈霞欧阳嘉穗熊歆睿王禹成都理工大学能源学院四川成都610059 中国石化西南油气分公司勘探开发研究院四川成都610041 中国石化西南油气分公司博士后工作站四川成都610016 中国石化西南石油工程公司地质录井分公司四川绵阳621000 页岩气评价与开采四川省重点实验室四川成都610073

川南下古生界下寒武统筇竹寺组及下志留统龙马溪组2套页岩,具有时代老、热演化程度高、缺乏镜质体等特点,因此,如何准确定量化评价有机质成熟度,一直是学术界争论的焦点。为此,文中总结了过成熟页岩各项成熟度实验过程及数据应用时的注... 详细信息

川南下古生界下寒武统筇竹寺组及下志留统龙马溪组2套页岩,具有时代老、热演化程度高、缺乏镜质体等特点,因此,如何准确定量化评价有机质成熟度,一直是学术界争论的焦点。为此,文中总结了过成熟页岩各项成熟度实验过程及数据应用时的注意事项:1)热解实验需要人工识别真实的热解烃峰值温度,排除钻井液污染产生"假峰"的影响,获取真实的热解峰温;2)分析每个样品所有测点沥青质反射率及笔石反射率的分布特征,剔除不可靠测值的影响;3)伊利石结晶度可应用于伊蒙混层比小于15%的过成熟页岩,当无测点或测点少时,作为过成熟度的可靠指标。最终采用了岩石热解峰温-沥青质反射率-笔石反射率-伊利石结晶度综合评价方法,明确了永川、威远地区龙马溪组镜质体反射率(Ro)为2.05%~2.35%;井研地区筇竹寺组Ro为2.57%~2.74%。

关键词：页岩过成熟沥青反射率笔石反射率伊利石结晶度(川南

泮托拉唑和硫糖铝片治疗反流性食管炎患者的临床效果比较

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临床合理用药杂志 2019年第5期12卷 19-20页

作者：崔红英吴平英但丽霞四川省井研县人民医院 613100

目的观察比较泮托拉唑和硫糖铝片治疗反流性食管炎患者的临床效果。方法选取医院收治的反流性食管炎患者86例为研究对象,随机分为观察组和对照组,每组43例。对照组接受硫糖铝片治疗,观察组接受泮托拉唑治疗,比较2组临床疗效和临床症状... 详细信息

目的观察比较泮托拉唑和硫糖铝片治疗反流性食管炎患者的临床效果。方法选取医院收治的反流性食管炎患者86例为研究对象,随机分为观察组和对照组,每组43例。对照组接受硫糖铝片治疗,观察组接受泮托拉唑治疗,比较2组临床疗效和临床症状改善情况。结果观察组总有效率为95. 35%,高于对照组的79. 07%(P 0. 05),治疗后,2组各临床症状评分较治疗前均下降,且观察组胸骨后灼烧感、泛酸、胸痛症状评分低于对照组(P均<0. 01)。结论泮托拉唑治疗反流性食管炎患者临床效果显著,可有效缓解患者临床症状,具有重要推广意义。

关键词：反流性食管炎泮托拉唑硫糖铝片临床疗效

Sub-percent precision measurement of neutrino oscillation parameters with JUNO

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Chinese Physics C 2022年第12期46卷 28-49页

作者： Angel Abusleme Thomas Adam Shakeel Ahmad Rizwan Ahmed Sebastiano Aiello Muhammad Akram Abid Aleem Fengpeng An Qi An Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde Marcondes de André Didier Auguste Weidong Bai Nikita Balashov Wander Baldini Andrea Barresi Davide Basilico Eric Baussan Marco Bellato Antonio Bergnoli Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Jose Busto Ilya Butorov Anatael Cabrera Barbara Caccianiga Hao Cai xiao Cai Yanke Cai Zhiyan Cai Riccardo Callegari Antonio Cammi Agustin Campeny Chuanya Cao Guofu Cao Jun Cao Rossella Caruso Cédric Cerna Chi Chan Jinfan Chang Yun Chang Guoming Chen Pingping Chen Po-An Chen Shaomin Chen Xurong Chen Yixue Chen Yu Chen Zhiyuan Chen Zikang Chen Jie Cheng Yaping Cheng Yu Chin Cheng Alexey Chetverikov Davide Chiesa Pietro Chimenti Artem Chukanov Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Flavio Dal Corso Olivia Dalager Christophe De La Taille Zhi Deng Ziyan Deng Wilfried Depnering Marco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Dmitry Dolzhikov Georgy Donchenko Jianmeng Dong Evgeny Doroshkevich Marcos Dracos Frédéric Druillole Ran Du Shuxian Du Stefano Dusini Martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri Donghua Fan Lei Fan Jian Fang Wenxing Fang Marco Fargetta Dmitry Fedoseev Zhengyong Fei Li-Cheng Feng Qichun Feng Richard Ford Amélie Fournier Haonan Gan Feng Gao Alberto Garfagnini Arsenii Gavrikov Marco Giammarchi Nunzio Giudice Maxim Gonchar Guanghua Gong Hui Gong Yuri Gornushkin Alexandre Göttel Marco Grassi Vasily Gromov Minghao Gu xiaofei Gu Yu Gu Mengyun Guan Yuduo Guan Nunzio Guardone Cong Guo Jingyuan Guo Wanlei Guo Xinheng Guo Yuhang Guo Paul Hackspacher Caren Hagner Ran Han Yang Han Miao He Wei He Tobias Heinz Patrick Hellmuth Yuekun Heng Rafael Herrera YuenKeung Ho Yerevan Physics Institute YerevanArmenia UniversiéLibre de Bruxelles BrusselsBelgium Universidade Estadual de Londrina LondrinaBrazil Pontificia Universidade Catolica do Rio de Janeiro Rio de JaneiroBrazil Pontificia Universidad Católica de Chile SantiagoChile Universidad Tecnica Federico Santa Maria ValparaisoChile Beijing Institute of Spacecraft Environment Engineering BeijingChina Beijing Normal University BeijingChina China Institute of Atomic Energy BeijingChina Institute of High Energy Physics BeijingChina North China Electric Power University BeijingChina School of Physics Peking UniversityBeijingChina Tsinghua University BeijingChina University of Chinese Academy of Sciences BeijingChina Jilin University ChangchunChina College of Electronic Science and Engineering National University of Defense TechnologyChangshaChina Chongqing University ChongqingChina Dongguan University of Technology DongguanChina Jinan University GuangzhouChina Sun Yat-Sen University GuangzhouChina Harbin Institute of Technology HarbinChina University of Science and Technology of China HefeiChina The Radiochemistry and Nuclear Chemistry Group in University of South China HengyangChina Wuyi University JiangmenChina Shandong University JinanChinaand Key Laboratory of Particle Physics and Particle Irradiation of Ministry of EducationShandong UniversityQingdaoChina Institute of Modern Physics Chinese Academy of SciencesLanzhouChina Nanjing University NanjingChina Guangxi University NanningChina East China University of Science and Technology ShanghaiChina School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghaiChina Tsung-Dao Lee Institute Shanghai Jiao Tong UniversityShanghaiChina Institute of Hydrogeology and Environmental Geology Chinese Academy of Geological SciencesShijiazhuangChina Nankai University TianjinChina Wuhan University WuhanChina Xi'an Jiaotong University Xi'anChina xiamen University XiamenChina School of Physics and Microelectronics Zhengzhou UniversityZhengzhou

JUNO is a multi-purpose neutrino observatory under construction in the south of *** publication presents new sensitivity estimates for the measurement of the △m_(31)^(2),△m_(21)^(2),sin^(2)θ_(12),and sin^(2)θ_(13) oscillation parameters using reactor antineutrinos,which is one of the primary physics goals of the *** sensitivities are obtained using the best knowledge available to date on the location and overburden of the experimental site,the nuclear reactors in the surrounding area and beyond,the detector response uncertainties,and the reactor antineutrino spectral shape constraints expected from the TAO satellite *** is found that the △m_(21)^(2) and sin^(2)θ_(12) oscillation parameters will be determined to 0.5%precision or better in six years of data *** the same period,the △m_(31)^(2) parameter will be determined to about 0.2%precision for each mass ordering *** new precision represents approximately an order of magnitude improvement over existing constraints for these three parameters.

关键词： neutrino oscillation reactor antineutrino precision measurement JUNO

Feasibility and physics potential of detecting ^(8)B solar neutrinos at JUNO

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Chinese Physics C 2021年第2期45卷 93-110页

作者： Angel Abusleme Thomas Adam Shakeel Ahmad Sebastiano Aiello Muhammad Akram Nawab Ali Fengpeng An Guangpeng An Qi An Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde Marcondes de André Didier Auguste Andrej Babic Wander Baldini Andrea Barresi Eric Baussan Marco Bellato Antonio Bergnoli Enrico Bernieri David Biare Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Max Buesken Mario Buscemi Jose Busto Ilya Butorov Anatael Cabrera Hao Cai xiao Cai Yanke Cai Zhiyan Cai Antonio Cammi Agustin Campeny Chuanya Cao Guofu Cao Jun Cao Rossella Caruso Cédric Cerna Jinfan Chang Yun Chang Pingping Chen Po-An Chen Shaomin Chen Shenjian Chen Xurong Chen Yi-Wen Chen Yixue Chen Yu Chen Zhang Chen Jie Cheng Yaping Cheng Alexander Chepurnov Davide Chiesa Pietro Chimenti Artem Chukanov Anna Chuvashova Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Salvatore Costa Flavio Dal Corso Christophe De La Taille Jiawei Deng Zhi Deng Ziyan Deng Wilfried Depnering Marco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Georgy Donchenko Jianmeng Dong Damien Dornic Evgeny Doroshkevich Marcos Dracos Frédéric Druillole Shuxian Du Stefano Dusini Martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri Lukas Fajt Donghua Fan Lei Fan Can Fang Jian Fang Marco Fargetta Anna Fatkina Dmitry Fedoseev Vladko Fekete Li-Cheng Feng Qichun Feng Richard Ford Andrey Formozov Amélie Fournier Haonan Gan Feng Gao Alberto Garfagnini Alexandre Göttel Christoph Genster Marco Giammarchi Agnese Giaz Nunzio Giudice Franco Giuliani Maxim Gonchar Guanghua Gong Hui Gong Oleg Gorchakov Yuri Gornushkin Marco Grassi Christian Grewing Maxim Gromov Vasily Gromov Minghao Gu xiaofei Gu Yu Gu Mengyun Guan Nunzio Guardone Maria Gul Cong Guo Jingyuan Guo Wanlei Guo Xinheng Guo Yuhang Guo Paul Hackspacher Caren Hagner Ran Han Yan Yerevan Physics Institute YerevanArmenia UniversitéLibre de Bruxelles BrusselsBelgium Universidade Estadual de Londrina LondrinaBrazil Pontificia Universidade Catolica do Rio de Janeiro RioBrazil Pontificia Universidad Católica de Chile SantiagoChile Universidad Tecnica Federico Santa Maria ValparaisoChile Beijing Institute of Spacecraft Environment Engineering BeijingChina Beijing Normal University BeijingChina China Institute of Atomic Energy BeijingChina Institute of High Energy Physics BeijingChina North China Electric Power University BeijingChina School of Physics Peking UniversityBeijingChina Tsinghua University BeijingChina University of Chinese Academy of Sciences BeijingChina Jilin University ChangchunChina College of Electronic Science and Engineering National University of Defense TechnologyChangshaChina Chongqing University ChongqingChina Dongguan University of Technology DongguanChina Jinan University GuangzhouChina Sun Yat-Sen University GuangzhouChina Harbin Institute of Technology HarbinChina University of Science and Technology of China HefeiChina The Radiochemistry and Nuclear Chemistry Group in University of South China HengyangChina Wuyi University JiangmenChina Shandong University JinanChina Institute of Modern Physics Chinese Academy of SciencesLanzhouChina Nanjing University NanjingChina Guangxi University NanningChina East China University of Science and Technology ShanghaiChina School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghaiChina Tsung-Dao Lee Institute Shanghai Jiao Tong UniversityShanghaiChina Institute of Hydrogeology and Environmental Geology Chinese Academy of Geological SciencesShijiazhuangChina Nankai University TianjinChina Wuhan University WuhanChina Xi’an Jiaotong University Xi’anChina xiamen University XiamenChina School of Physics and Microelectronics Zhengzhou UniversityZhengzhouChina Institute of Physics National Chiao-Tung University Hsinchu National United University Miao-Li Department of Physics National T

The Jiangmen Underground Neutrino Observatory(JUNO)features a 20 kt multi-purpose underground liquid scintillator sphere as its main *** of JUNO's features make it an excellent location for^8B solar neutrino measurements,such as its low-energy threshold,high energy resolution compared with water Cherenkov detectors,and much larger target mass compared with previous liquid scintillator *** this paper,we present a comprehensive assessment of JUNO's potential for detecting^8B solar neutrinos via the neutrino-electron elastic scattering process.A reduced 2 MeV threshold for the recoil electron energy is found to be achievable,assuming that the intrinsic radioactive background^(238)U and^(232)Th in the liquid scintillator can be controlled to 10^(-17)g/*** ten years of data acquisition,approximately 60,000 signal and 30,000 background events are *** large sample will enable an examination of the distortion of the recoil electron spectrum that is dominated by the neutrino flavor transformation in the dense solar matter,which will shed new light on the inconsistency between the measured electron spectra and the predictions of the standard three-flavor neutrino oscillation *** m^(2)_(21)=4.8times10^(-5);(7.5times10^(-5))eV^(2),JUNO can provide evidence of neutrino oscillation in the Earth at approximately the 3sigma(2sigma)level by measuring the non-zero signal rate variation with respect to the solar zenith ***,JUNO can simultaneously measureDelta m^2_(21)using^8B solar neutrinos to a precision of 20% or better,depending on the central value,and to sub-percent precision using reactor antineutrinos.A comparison of these two measurements from the same detector will help understand the current mild inconsistency between the value of Delta m^2_(21)reported by solar neutrino experiments and the KamLAND experiment.

关键词： neutrino oscillation solar neutrino JUNO

JUNO sensitivity on proton decay p→νK^(+)searches

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Chinese Physics C 2023年第11期47卷 7-22页

作者： Angel Abusleme Thomas Adam Shakeel Ahmad Rizwan Ahmed Sebastiano Aiello Muhammad Akram 安丰鹏安琪 Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde Marcondes de André Didier Auguste Nikita Balashov Wander Baldini Andrea Barresi Davide Basilico Eric Baussan Marco Bellato Antonio Bergnoli Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Mario Buscemi Jose Busto Ilya Butorov Anatael Cabrera Barbara Caccianiga 蔡浩蔡啸蔡严克蔡志岩 Riccardo Callegari Antonio Cammi Agustin Campeny 曹传亚曹国富曹俊 Rossella Caruso Cédric Cerna 常劲帆 Yun Chang 陈平平 Po-An Chen 陈少敏陈旭荣 Yi-Wen Chen 陈义学陈羽陈长程捷程雅苹 Alexey Chetverikov Davide Chiesa Pietro Chimenti Artem Chukanov Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Flavio Dal Corso Olivia Dalager Christophe De La Taille 邓智邓子艳 Wilfried Depnering Marco Diaz Xuefeng Ding 丁雅韵 Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Dmitry Dolzhikov Georgy Donchenko 董建蒙 Evgeny Doroshkevich Marcos Dracos Frédéric Druillole 杜然杜书先 Stefano Dusini Martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri Ulrike Fahrendholz 范东华樊磊方建方文兴 Marco Fargetta Dmitry Fedoseev Li-Cheng Feng 冯启春 Richard Ford Amélie Fournier 甘浩男 Feng Gao Alberto Garfagnini Arsenii Gavrikov Marco Giammarchi Agnese Giaz Nunzio Giudice Maxim Gonchar 龚光华宫辉 Yuri Gornushkin Alexandre Göttel Marco Grassi Christian Grewing Vasily Gromov 顾旻皓谷肖飞古宇关梦云 Nunzio Guardone Maria Gul 郭聪郭竞渊郭万磊郭新恒郭宇航 Paul Hackspacher Caren Hagner 韩然 Yang Han Muhammad Sohaib Hassan 何苗何伟 Tobias Heinz Patrick Hellmuth 衡月昆 Rafael Herrera 贺远强侯少静 Yee Hsiung Bei-Zhen Hu 胡航胡健润胡俊胡守扬胡涛胡宇翔胡焯钧黄春豪黄桂鸿黄翰雄黄文昊黄鑫黄性涛黄永波惠加琪霍雷霍文驹 Cédric Huss Safeer Hussain Ara Ioannisian Roberto Isocrate Beatrice Jelmini Kuo-Lun Jen Ignacio Jeria 季筱璐吉星曌贾慧慧贾俊基蹇司玉蒋荻蒋炜江晓山金如意荆小平 Cécile Jollet Jari Joutsenvaara Sirichok Jungthawan Leonidas Kalousis Philipp Ka Pontificia Universidad Católica de Chile SantiagoChile IPHC Universitéde StrasbourgCNRS/IN2P3F-67037 StrasbourgFrance Pakistan Institute of Nuclear Science and Technology IslamabadPakistan INFN Catania and Dipartimento di Fisica e Astronomia dell Universitàdi Catania CataniaItaly East China University of Science and Technology ShanghaiChina University of Science and Technology of China HefeiChina Joint Institute for Nuclear Research DubnaRussia INFN Sezione di Milano and Dipartimento di Fisica dell Universitàdi Milano MilanoItaly Department of Physics Faculty of ScienceChulalongkorn UniversityBangkokThailand IJCLab UniversitéParis-SaclayCNRS/IN2P391405 OrsayFrance Department of Physics and Earth Science University of Ferrara and INFN Sezione di FerraraFerraraItaly INFN Milano Bicocca and University of Milano Bicocca MilanoItaly INFN Sezione di Padova PadovaItaly III.Physikalisches Institut B RWTH Aachen UniversityAachenGermany Eberhard Karls Universität Tübingen Physikalisches InstitutTübingenGermany Institute of High Energy Physics BeijingChina SUBATECH Universitéde NantesIMT AtlantiqueCNRS-IN2P3NantesFrance Univ.Bordeaux CNRSLP2IUMR 5797F-33170 GradignanFrance Department of Physics National Taiwan UniversityTaipei Dipartimento di Fisica e Astronomia dell’Universitàdi Padova and INFN Sezione di Padova PadovaItaly University of Roma Tre and INFN Sezione Roma Tre RomaItaly Aix Marseille Univ CNRS/IN2P3CPPMMarseilleFrance Wuhan University WuhanChina INFN Milano Bicocca and Politecnico of Milano MilanoItaly National United University Miao-Li Dongguan University of Technology DongguanChina Tsinghua University BeijingChina Institute of Modern Physics Chinese Academy of SciencesLanzhouChina Institute of Physics National Yang Ming Chiao Tung UniversityHsinchu North China Electric Power University BeijingChina Sun Yat-Sen University GuangzhouChina Beijing Institute of Spacecraft Environment Engineering BeijingChina Universidade Estadual de Londrina LondrinaBrazil INFN Sez

The Jiangmen Underground Neutrino Observatory(JUNO)is a large liquid scintillator detector designed to explore many topics in fundamental *** this study,the potential of searching for proton decay in the p→νK^(+)mode with JUNO is *** kaon and its decay particles feature a clear three-fold coincidence signature that results in a high efficiency for ***,the excellent energy resolution of JUNO permits suppression of the sizable background caused by other delayed *** on these advantages,the detection efficiency for the proton decay via p→νK^(+)is 36.9%±4.9%with a background level of 0.2±0.05(syst)±0.2(stat)events after 10 years of data *** estimated sensitivity based on 200 kton-years of exposure is 9.6×1033 years,which is competitive with the current best limits on the proton lifetime in this channel and complements the use of different detection technologies.

关键词： proton decay grand unified theories JUNO liquid scintillator detector