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甜樱桃‘红灯’果实发育过程中AsA积累与相关酶活性变化

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分子植物育种 2018年第8期16卷 2664-2670页

作者：倪知游梁东林玲吕秀兰高帆夏惠四川农业大学园艺学院成都611130 四川农业大学果蔬研究所成都611130

为了解甜樱桃果实抗坏血酸积累的特点及其生理机理,本研究以‘红灯’果实为试验材料,测定其发育过程中抗坏血酸(AsA)含量、谷胱甘肽(GSH)含量及AsA代谢相关酶活性的变化。结果表明:在‘红灯’果实发育过程中,AsA含量在花后0 d最高,之后... 详细信息

为了解甜樱桃果实抗坏血酸积累的特点及其生理机理,本研究以‘红灯’果实为试验材料,测定其发育过程中抗坏血酸(AsA)含量、谷胱甘肽(GSH)含量及AsA代谢相关酶活性的变化。结果表明:在‘红灯’果实发育过程中,AsA含量在花后0 d最高,之后快速下降再缓慢下降。GSH含量在花后10 d下降,随后迅速上升,在花后2. d达到最大值,后期又下降。AsA、GSH单果积累量发生于其整个发育期,在果实快速生长期积累量最大。果实发育过程中AsA代谢相关酶活性变化有所不同,L-半乳糖脱氢酶(GalDH)活性在整个果实发育期变化不大,抗坏血酸过氧化物酶(APX)活性呈现"降-升-降"的变化趋势;然而,L-半乳糖醛酸内酯酶(GalLDH)、单脱氢抗坏血酸还原酶(MDHAR)、脱氢抗坏血酸还原酶(DHAR)和谷胱甘肽还原酶(GR)的活性与AsA的含量变化趋势基本一致,均在花后0 d活性最高,随后是快速下降期和缓慢下降期。相关性分析表明,GalLDH、MDHAR活性与AsA含量呈极显著相关。本研究对提高甜樱桃抗坏血酸含量具有指导意义。

关键词：甜樱桃 '红灯’ AsA 酶活性

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温针灸配合药物治疗类风湿性关节炎疗效观察

上海针灸杂志 2017年第9期36卷 1082-1087页

作者：宋明霞裴建上海市金山区中西医结合医院上海201501 上海中医药大学附属龙华医院上海200032

目的观察温针灸配合药物治疗类风湿关节炎的疗效。方法将100例类风湿关节炎患者采用随机数字表法分为治疗组和对照组,每组50例。治疗组采用温针灸配合口服药物的综合疗法,对照组单纯给予口服药物。两组均治疗10次为1个疗程,共治疗2.疗... 详细信息

目的观察温针灸配合药物治疗类风湿关节炎的疗效。方法将100例类风湿关节炎患者采用随机数字表法分为治疗组和对照组,每组50例。治疗组采用温针灸配合口服药物的综合疗法,对照组单纯给予口服药物。两组均治疗10次为1个疗程,共治疗2.疗程。观察两组治疗前后DAS2.评分和类风湿因子(RF)变化,并比较两组的临床疗效。结果治疗组总有效率为100.0%,对照组为86.0%,两组比较差异有统计学意义(P2.评分和RF比较,差异无统计学意义(P>0.05),两组治疗前后DAS2.评分和RF的差值比较,差异有统计学意义(P<0.05)。结论温针灸配合药物治疗类风湿关节炎,临床疗效优于单纯口服药物。

关键词：温针疗法针药并用关节炎,类风湿 DAS2.评分类风湿因子

Analytical Solutions for an Isotropic Elastic Half-Plane with Complete Surface Effects Subjected to a Concentrated/Uniform Surface Load

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Acta Mechanica Solida Sinica 2024年第3期37卷 371-384页

作者： xia-Hui Pan School of Civil Engineering Henan Polytechnic UniversityJiaozuo454003China

Within the context of Gurtin-Murdoch surface elasticity theory,closed-form analytical solutions are derived for an isotropic elastic half-plane subjected to a concentrated/uniform surface *** the effects of residual surface stress and surface elasticity are *** stress function method and Fourier integral transform technique are *** solutions are provided in a compact manner that can easily reduce to special situations that take into account either one surface effect or none at *** results indicate that surface effects generally lower the stress levels and smooth the deformation profiles in the *** elasticity plays a dominant role in the in-plane elastic fields for a tangentially loaded half-plane,while the effect of residual surface stress is fundamentally crucial for the out-of-plane stress and displacement when the half-plane is normally *** the remaining situations,combined effects of surface elasticity and residual surface stress should be *** results for a concentrated surface force serve essentially as fundamental solutions of the Flamant and the half-plane Cerruti problems with surface *** solutions presented in this work may be helpful for understanding the contact behaviors between solids at the nanoscale.

关键词： Surface effects Residual surface stress Surface elasticity Half-plane Analytical solutions

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环状RNA的研究新进展

生命科学 2017年第11期29卷 1141-1148页

作者：王坚黄嘉楠宋元林夏世金复旦大学附属中山医院呼吸科上海200032 复旦大学附属华东医院上海市老年医学研究所上海200040

环状RNA(circular RNA,circ RNA)作为非编码RNA家族成员,具有特征性的共价闭合环结构。circ RNA在各种生物中广泛表达,具有种属、组织、疾病及发育阶段相关的特异性,与各种疾病,尤其是恶性肿瘤的发生发展密切相关。circ RNA的主要功能... 详细信息

环状RNA(circular RNA,circ RNA)作为非编码RNA家族成员,具有特征性的共价闭合环结构。circ RNA在各种生物中广泛表达,具有种属、组织、疾病及发育阶段相关的特异性,与各种疾病,尤其是恶性肿瘤的发生发展密切相关。circ RNA的主要功能是作为海绵吸附mi RNA发挥生物学功能,同时还具有调控转录和转录后过程、可变剪接、编码蛋白以及充当蛋白诱饵等作用。目前已有多种预测方法用于circ RNA的鉴定。现就circ RNA的特征、分类、形成、功能、计算方法学以及在疾病发生中的最新研究成果进行全面阐述。

关键词：环状RNA 非编码RNA miRNA海绵可变剪接疾病

Computational modelling of gas–liquid–solid multiphase free surface flow with and without evaporation

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Particuology 2024年第7期90卷 218-235页

作者： Huihuang xia Marc Kamlah Institute for Applied Materials(IAM) Karlsruhe Institute of Technology(KIT)Hermann-von Helmholtz-Platz 176344 Eggenstein-LeopoldshafenGermany

Gas–liquid–solid multiphase systems are ubiquitous in engineering applications,*** printing,spray drying and *** a numerical framework for modelling these multiphase systems is of great *** improved,resolved computational fluid dynamics-discrete element method(CFD-DEM)framework is developed to model the multiphase free surface flow with and without *** improved capillary force model is developed to compute the capillary interactions for partially floating particles at a free *** well-known benchmark cases,namely drag coefficient calculation,the single sphere settling,and drafting-kissing-tumbling of two particles are conducted to validate the resolved CFD-DEM *** turns out that the resolved CFD-DEM model developed in this paper can accurately calculate the fluid–solid interactions and predict the trajectory of solid particles interacting with the liquid *** demonstrations,namely two particles moving along a free surface when the liquid phase evaporates,and particle transport and accumulations inside an evaporating sessile droplet show the performance of the resolved model.

关键词： Capillary force Discrete element method Liquid bridge Particle transport Resolved CFD-DEM Volume of fluid

Seasonal thermal energy storage using natural structures:GIS-based potential assessment for northern China

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Building Simulation 2024年第4期17卷 561-574页

作者： Yichi Zhang Jianjun xia Midea HVAC Heating&Ventilation Equipment Co. LtdFoshan528311China Building Energy Research Center Tsinghua UniversityBeijing100084China

Seasonal thermal energy storage(STES)allows storing heat for long-term and thus promotes the shifting of waste heat resources from summer to winter to decarbonize the district heating(DH)*** being a promising solution for sustainable energy system,large-scale STES for urban regions is lacking due to the relatively high initial investment and extensive land *** close the gap,this study assesses the potentials of using two naturally available structures for STES,namely valley and ground pit *** on geographical information system(GIS)methods,the available locations are searched from digital elevation model and selected considering several criteria from land uses and construction *** costs of dams to impound the reservoir and the yielded storage capacities are then quantified to guide the choice of suitable *** assessment is conducted for the northern China where DH systems and significant seasonal differences of energy demand *** total,2.2.3 valley sites and 75 ground pit sites are finally identified with the energy storage capacity of 15.2.billion GJ,which is much larger than the existing DH demand in northern *** results also prove that 682.valley sites can be achieved with a dam cost lower than 2. CNY/m^(3).By conducting sensitivity analysis on the design dam wall height and elevations,the choices of available natural structures are expanded but practical issues about water pressures and constructions are also ***,the identified sites are geographically mapped with nearest urban regions to reveal their roles in the DH *** general,560 urban regions are found with potential STES units and most of them have STES storage capacities larger than their own DH *** novel planning methodology of this study and publicly available datasets create possibilities for the implementations of large-scale STES in urban DH systems.

关键词： seasonal thermal energy storage geographical information system district heating water reservoir

Light People:*** D C Bradley(FRS)

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Light(Science & Applications) 2024年第9期13卷 1704-1719页

作者： Ruidong xia Ying Hu Key Laboratory for Organic Electronics&Information Displays(KLOEID) Jiangsu-Singapore Joint Research Center for Organic/Bio Electronics&Information DisplaysInstitute of Advanced Materials(IAM)Nanjing University of Posts and Telecommunications9 Wenyuan RoadNanjing 210023China Executive Management College of CHN ENERGY North District of Future Science CityChangping DistrictNo.7 Binhe AvenueBeijing 102211China

Editorial,The invention of organic light emitting diodes(LEDs)led to enormous excitement in both academe and industry in the late 1980’***,large area solution processability,roll-to-roll printing,low cost,and environmentally friendly are some of the advantages of organic semiconductor materials,which brought a new horizon for *** with the achievement of organic solar cells,transistors,lasers,and amplifiers,this has demonstrated potential applications of organic semiconductors in displays,lighting,solar energy generation,electronics,sensing and imaging,and many aspects of *** an enlightened conversation with Light:Science&Applications,*** Bradley(FRS),a pioneer in the field,shared his deep insights on past,current,and future exciting developments of organic optoelectronic materials and *** particular,he expressed his opinion on the hot topics related to organic optoelectronics research and application,such as the relationship between organic and inorganic semiconductors and the challenge of electrically pumped organic *** a successful scientist,Donal has also been co-founder of several organic optoelectronics innovation companies and research centers and a long-term academic administrator serving as a Head of Department,Centre Director,and Vice-Rector for Research at Imperial College,Head of the Mathematical,Physical,and Life Sciences Division at the University of Oxford,Vice-President for Research at King Abdullah University of Science and Technology and now Vice-President for Research and Innovation at NEOM U and Executive Director of the NEOM Education,Research and Innovation *** this interview,we also explore the major roles and events in Donal’s career experience from the invention of the first conjugated polymer LED in the world to the set-up of entrepreneurial companies,from Cambridge to Sheffield,Imperial College,and Oxford,from the UK to overseas,and from the establishment of the Cent

关键词： companies Director Bradley

小动物实验用镁锰合金颈椎植入物制备及其可行性研究

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生物骨科材料与临床研究 2016年第5期13卷 5-8,12,I0003页

作者：耿芳姜明威夏天上海微创骨科医疗科技有限公司上海201203 上海市第一人民医院上海201620

目的应用镁锰合金材料制备用于小动物实验的颈椎植入物,验证表面处理对合金抗腐蚀能力的改进,并分析其用于小动物实验的可行性。方法根据新西兰兔颈椎解剖设计镁锰合金(Mg-1.3Mn)颈椎植入物,应用微弧氧化方法在镁合金表面制备含硅生物... 详细信息

目的应用镁锰合金材料制备用于小动物实验的颈椎植入物,验证表面处理对合金抗腐蚀能力的改进,并分析其用于小动物实验的可行性。方法根据新西兰兔颈椎解剖设计镁锰合金(Mg-1.3Mn)颈椎植入物,应用微弧氧化方法在镁合金表面制备含硅生物活性涂层。体外使用人工组织液浸泡,观察降解情况。体内实验将经表面处理的镁锰合金植入物及同尺寸未经表面处理的镁锰合金植入物、钛合金植入物植入兔颈椎椎体,观察不同时间植入物的体内降解情况。结果镁锰合金颈椎植入物制备成功,表面改性后其抗腐蚀性能明显提高,经手术成功固定于兔颈椎椎体上,与未经表面改性的镁锰合金植入物相比,体内、体外的降解速度均显著降低,扫描电镜及能谱分析等结果表明表面改性的镁锰合金抗腐蚀性有较大改善。结论镁锰合金颈椎植入物可用于小动物颈椎部位实验,适当的表面处理能够有效改进合金的抗腐蚀性能。

关键词：镁锰合金微弧氧化颈椎动物实验

Minimum mass-entransy dissipation profile for one-way isothermal diffusive mass-transfer process with mass-resistance and massleakage

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Science China(Technological Sciences) 2024年第8期67卷 2427-2435页

作者： CHEN LinGen xia ShaoJun Institute of Thermal Science and Power Engineering Wuhan Institute of TechnologyWuhan 430205China School of Mechanical Electrical EngineeringWuhan Institute of TechnologyWuhan 430205China School of Power Engineering Naval University of EngineeringWuhan 430033China

As a new concept,mass-entransy is one of the twins in the core of entransy *** can describe mass-transfer ability for masstransfer processes(MTPes),just as thermal-entransy for describing heat-transfer ***,mass-entransy dissipation can be utilized to evaluate the loss of mass-transfer *** mass-entransy dissipation(MMED) is utilized to optimize one-way isothermal diffusive MTPes with mass-leakage and mass-transfer law(g ∝ Δ(c),where c means concentration).For a given net amount of mass-transferred key components at the low-concentration side,optimality-condition for the MMED of isothermal diffusive MTPes is obtained by using the *** of the amount of mass-transferred and mass-leakage on optimal results are analyzed,and the obtained optimization profiles are compared with those for MTP profiles of constant-concentration-difference(c_1-c_2.const) and constant-concentration-ratio(c_1/c_2.const).The product of square of key-component-concentration(KCC) difference between high-and low-concentration sides and inert component concentration at high-concentration side for the MMED of the MTP with no mass-leakage is a constant,and the optimal relationship of the KCCs between high-and low-concentration sides with mass-leakage is significantly different from the *** mass-leakage is relatively small,the MTP with c_1-c_2.const strategy is superior to that with c_1/c_2.const strategy,and the latter is superior to the former with an increase in mass-leakage.A combination of mass-entransy concept,finite-time thermodynamics,and averaged-optimization-method is a meaningful tool for optimizing MTPes.

关键词： diffusive mass-transfer-law mass-leakage one-way isothermal mass-transfer minimum mass-entransy dissipation finite-time thermodynamics averaged-optimization-method