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Production induced fracture closure of deep shale gas well under thermo-hydro-mechanical conditions

Petroleum Science 2024年第3期21卷 1796-1813页

作者： Shi-Ming Wei yang xia Yan Jin Xu-yang Guo Jing-Yu Zi Kai-Xuan Qiu Si-Yuan Chen College of Science China University of Petroleum(Beijing)Beijing102249China CNOOC Research Institute Ltd Beijing100028China The University of Hong Kong Hong Kong999077China

Deep shale gas reservoirs have geological characteristics of high temperature,high pressure,high stress,and inferior ability to pass through *** multi-stage fractured horizontal well is the key to exploiting the deep shale gas ***,during the production process,the effectiveness of the hydraulic fracture network decreases with the closure of fractures,which accelerates the decline of shale gas *** this paper,we addressed the problems of unclear fracture closure mechanisms and low accuracy of shale gas production prediction during deep shale gas *** we established the fluid—solid—heat coupled model coupling the deformation and fluid flow among the fracture surface,proppant and the shale *** the fluid—solid—heat coupled model was applied to the fracture network,it was well solved by our numerical method named discontinuous discrete fracture *** with the conventional discrete fracture method,the discontinuous discrete fracture method can describe the three-dimensional morphology of the fracture while considering the effect of the change of fracture surface permeation coefficient on the coupled fracture—matrix flow and describing the displacement discontinuity across the *** simulations revealed that the degree of fracture closure increases as the production time proceeds,and the degree of closure of the secondary fractures is higher than that of the primary *** creep and proppant embedment both increase the degree of fracture *** reduction in fracture surface permeability due to proppant embedment reduces the rate of fluid transfer between matrix and fracture,which has often been overlooked in the ***,it significantly impacts shale gas production,with calculations showing a 24.7%cumulative three-year yield *** study is helpful to understand the mechanism of hydraulic fracture ***,it provides the theoretical guidance for maintaining the long

关键词： Shalegas Fracture closure Fluid-solid-heat coupling Discontinuous discrete fracture

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A facile strategy for large-scale production of 2D nanosheets exfoliated by three-roll milling

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Journal of Advanced Ceramics 2024年第1期13卷 11-18页

作者： Xin Wang yang xia Juntong Huang Yao Su Zhi Chen Linlin Chen Zhaohui Wu Zhijun Feng Huiyong yang Xibao Li School of Materials Science and Engineering Nanchang Hangkong UniversityNanchang 330063China

Two-dimensional(2D)nanomaterials,such as graphene,MoS_(2),and MAX,have attracted increasing research attention in recent years due to their unique structural and performance ***,their complex production processes and equipment requirements are significant issues affecting their widespread ***,with an exfoliation strategy using three-roll milling,we present a simple,cost-effective,and extensible method to produce multilayer graphene,BN,MoS_(2),and Ti_(3)AlC_(2) *** roller and phenolic resin created three kinds of forces on the layered 2D materials,i.e.,shear forces,compressive forces,and adhesive forces,which exfoliated layered materials from their edges and surfaces into ***,the exfoliated materials were ultrasonically washed with alcohol,treated with ultrasonic vibration,and centrifuged to obtain 2D *** easy operation and high yield are attractive for research based on the construction of high-performance 2D nanosheet-based devices at low ***,the obtained multilayer graphene and MoS_(2) nanosheets were used as anode materials of sodium/potassium-ion batteries,respectively,to test their electrochemical *** performances are obtained compared with their primary bulk materials.

关键词： two-dimensional(2D)nanosheets exfoliation three-roll milling(TRM) sodium/potassium-ion batteries

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Ultra-homogeneous dense Ag nano layer enables long lifespan solid-state lithium metal batteries

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Journal of Energy Chemistry 2024年第9期96卷 110-119页

作者： Yaning Liu Tianqi yang Ruyi Fang Chengwei Lu Ruojian Ma Ke Yue Zhen xiao xiaozheng Zhou Wenkui Zhang Xinping He Yongping Gan Jun Zhang Xinhui xia Hui Huang Xinyong Tao yang xia College of Materials Sciencend Engineering Zhejiang University of TechnologyHangzhou 310014ZhejiangChina Key Laboratory of Rare Earth Optoelectronic Materialsnd Devices of Zhejiang Province Institute of Optoelectronic Materialsnd DevicesChina Jiliang UniversityHangzhou 310018ZhejiangChina

The unstable electrolyte/lithium(Li)anode interface has been one of the key challenges in realizing high energy density solid-state lithium metal batteries(LMBs)***,a dense and uniform silver(Ag)nano interlayer with a thickness of∼35 nm is designed accurately by magnetron sputtering technology to optimize the electrolyte/Li anode *** Ag nano layer reacts with Li metal anode to in-situ form Li-Ag alloy,thus enhancing the physical interfacial contact,and further improving the interfacial wettability and *** particular,the Li-Ag alloy is inclined to form AgLi phase proved by cryo-TEM and DFT,effectively preventing SN from continuously“attacking”the Li metal anode due to the lower adsorption of succinonitrile(SN)molecules on AgLi than that of pure Li metal,thereby significantly reinforcing the interfacial ***,the enhanced physical and chemical stability of electrolyte/Li anode interface promotes the homogeneous deposition of Li^(+)and inhibits the dendrite *** Li-symmetric cell maintains stable operation for up to 1700 h and the cycling stability of LiFePO_(4)|SPE|Li full cell is remarkably improved at room temperature(capacity retention rate of 91.9%for 200 cycles).This work opens an effective way for accurate and controllable interface design of long lifespan solid-state LMBs.

关键词： Silvernano layer Poly(ethylene oxide) Solid polymer electrolyte Succinonitrile Lithium metal battery

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An improved deep dilated convolutional neural network for seismic facies interpretation

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Petroleum Science 2024年第3期21卷 1569-1583页

作者： Na-xia yang Guo-Fa Li Ting-Hui Li Dong-Feng Zhao Wei-Wei Gu State Key Laboratory of Petroleum Resources and Engineering CNPC Key Lab of Geophysical ExplorationChina University of Petroleum(Beijing)Beijing 102249China Dagang Branch Research InstituteBGPTianjin300280China

With the successful application and breakthrough of deep learning technology in image segmentation,there has been continuous development in the field of seismic facies interpretation using convolutional neural *** intelligent and automated methods significantly reduce manual labor,particularly in the laborious task of manually labeling seismic ***,the extensive demand for training data imposes limitations on their wider *** overcome this challenge,we adopt the UNet architecture as the foundational network structure for seismic facies classification,which has demonstrated effective segmentation results even with small-sample training ***,we integrate spatial pyramid pooling and dilated convolution modules into the network architecture to enhance the perception of spatial information across a broader *** seismic facies classification test on the public data from the F3 block verifies the superior performance of our proposed improved network structure in delineating seismic facies *** analysis against the traditional UNet model reveals that our method achieves more accurate predictive classification results,as evidenced by various evaluation metrics for image ***,the classification accuracy reaches an impressive 96%.Furthermore,the results of seismic facies classification in the seismic slice dimension provide further confirmation of the superior performance of our proposed method,which accurately defines the range of different seismic *** approach holds significant potential for analyzing geological patterns and extracting valuable depositional information.

关键词： Seismic facies interpretation Dilated convolution Spatial pyramid pooling Internal feature maps Compound loss function

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High performance photodegradation resistant PVA@TiO_(2)/carboxyl-PES self-healing reactive ultrafiltration membrane

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Chinese Journal of Chemical Engineering 2024年第2期66卷 31-39页

作者： Yu Liang Yuanfang Fan Zhongmin Su Mingxin Huo xia yang Hongliang Huo Chi Wang Zhi Geng College of Environment Engineering Research Center of Low-Carbon Treatment and Green Development of Polluted Water in Northeast ChinaMinistry of EducationNortheast Normal UniversityChangchun 130117China School of Science Hainan UniversityHaikou 570225China

The occurrence of ultrafiltration(UF)membrane fouling frequently hampers the sustainable advancement of UF *** self-cleaning UF membranes can effectively alleviate the problem of membrane ***,the self-cleaning process may accelerate membrane *** these concerns,we present an innovative design concept for composite self-healing materials based on self-cleaning UF *** begin,TiO_(2)nanoparticles were incorporated into the polymer molecular structure via molecular design,resulting in the synthesis of TiO_(2)/carboxyl-polyether sulfone(PES)hybrid ***,the nonsolvent-induced phase inversion technique was employed to prepare a novel of UF ***,a polyvinyl alcohol(PVA)hydrogel coating was applied to the hybrid UF membrane surface to create PVA@TiO_(2)/carboxyl-PES self-healing reactive UF *** establishing a covalent bond,the TiO_(2)nanoparticles were effectively and uniformly dispersed within the UF membrane,leading to exceptional self-cleaning ***,the water-absorbing and swelling properties of PVA hydrogel,along with its capacity to form hydrogen bonds with water molecules,resulted in UF membranes with improved hydrophilicity and active self-healing *** results demonstrated that the water contact angle of PVA@5%TiO_(2)/carboxyl-PES UF membrane was 43.1°.Following a 1-h exposure to simulated solar exposure,the water flux recovery ratio increased from 48.16%to 81.03%.Moreover,even after undergoing five cycles of 12-h simulated sunlight exposure,the UF membranes exhibited a consistent retention rate of over 97%,thus fully demonstrating their exceptional self-cleaning,antifouling,and selfhealing *** anticipate that the self-healing reactive UF membrane system will serve as a pioneering and comprehensive solution for the self-cleaning antifouling challenges encountered in UF membranes while also effectively mitigating the aging effects of reactive

关键词： Ultrafiltration membrane Self-cleaning Self-healing Poly(aryl ether sulfone)

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Surface demineralized freeze-dried bone allograft followed by reimplantation in a failed mandibular dental implant

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Regenerative Biomaterials 2024年第1期3卷 82-93页

作者： Jing Zhang Jie Wang Jiayi You Xuan Qin Huimin Chen xiantong Hu Yantao Zhao yang xia Jiangsu Key Laboratory of Oral Diseases Nanjing Medical UniversityNanjingJiangsu 210029PR China Jiangsu Province Engineering Research Center of Stomatological Translational Medicine Nanjing Medical UniversityNanjingJiangsu 210029PR China Department of Restorative Dental Sciences Faculty of DentistryThe University of Hong KongHong Kong SARPR China Senior Department of Orthopedics The Fourth Medical Center of PLA General HospitalBeijing100048PR China Beijing Engineering Research Center of Orthopedics Implants Beijing 100048PR China State Key Laboratory of Military Stomatology Xi'an 710032PR China

The removal of a failed implant with high torque causes significant damage to the surrounding tissue,compromising bone regeneration and subsequent osseointegration in the defect ***,we report a case of carrier screw fracture followed by immediate implant removal,bone grafting and delayed reimplantation.A dental implant with a fractured central carrier screw was removed using the bur-forceps *** resulting three-wall bone defect was filled with granular surface demineralized freeze-dried bone allograft(SD-FDBA).Cone-beam computerized tomography was performed at 1week,6months and 15months postoperatively and standardized for quantitative *** alveolar bone width and height at 15months post-surgery were about 91%of the original values,with a slightly lower bone density,calculated using the gray value *** graft site was reopened and was found to be completely healed with dense and vascularized bone along with some residual bone *** followed by restoration was performed 8months *** quality of regenerated bone following SD-FDBA grafting was adequate for osseointegration and longterm implant *** excellent osteogenic properties of SD-FDBA are attributed to its human origin,cortical bone-like structure,partly demineralized surfaces and bone morphogenetic protein-2-containing *** investigation with more cases and longer follow-up was required to confirm the final clinical effect.

关键词： dental implant implant failure allogeneic bone bone regeneration reimplantation

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Hyphae-mediated bioassembly of carbon fibers derivatives for advanced battery energy storage

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Carbon Energy 2024年第6期6卷 140-150页

作者： Lei Huang Zhong Qiu Ping Liu Xinhui xia Feng Cao Xinping He Chen Wang Wangjun Wan Yongqi Zhang yang xia Wenkui Zhang Minghua Chen Jiancang Zhou Department of Critical Care Medicine Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhouChina State Key Laboratory of Silicon Materials Key Laboratory of Advanced Materials and Applications for Batteries of Zhejiang ProvinceSchool of Materials Science&EngineeringZhejiang UniversityHangzhouChina College of Materials Science&Engineering Zhejiang University of TechnologyHangzhouChina State Key Laboratory of Photocatalysis on Energy and Environment Fuzhou UniversityFuzhouChina Department of Engineering Technology Huzhou CollegeHuzhouChina Zhejiang Academy of Science and Technology for Inspection&Quarantine HangzhouZhejiangChina Institute of Fundamental and Frontier Science University of Electronic Science and Technology of ChinaChengduChina Key Laboratory of Engineering Dielectric and Applications(Ministry of Education) School of Electrical and Electronic EngineeringHarbin University of Science and TechnologyHarbinChina

Ingenious design and fabrication of advanced carbon-based sulfur cathodes are extremely important to the development of high-energy lithium-sulfur batteries,which hold promise as the next-generation power ***,for the first time,we report a novel versatile hyphae-mediated biological assembly technology to achieve scale production of hyphae carbon fibers(HCFs)derivatives,in which different components including carbon,metal compounds,and semiconductors can be homogeneously assembled with HCFs to form composite *** mechanism of biological adsorption assembly is also *** a representative,reduced graphene oxides(rGOs)decorated with hollow carbon spheres(HCSs)successfully co-assemble with HCFs to form HCSs@rGOs/HCFs hosts for sulfur *** this unique architecture,not only large accommodation space for sulfur but also restrained volume expansion and fast charge transport paths are ***,multiscale physical barriers plus chemisorption sites are simultaneously established to anchor soluble lithium ***,the designed HCSs@rGOs/HCFs-S cathodes deliver a high capacity(1189 mA h g^(-1)at 0.1 C)and good high-rate capability(686 mA h g^(-1)at 5 C).Our work provides a new approach for the preparation of high-performance carbon-based electrodes for energy storage devices.

关键词： bioassembly carbon fibers energy storage graphene lithium-sulfur batteries

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Semaphorin 7A impairs barrier function in cultured human corneal epithelial cells in a manner dependent on nuclear factor-kappa B

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International Journal of Ophthalmology(English edition) 2024年第3期17卷 444-453页

作者： Cheng-Cheng yang Xiu-xia yang xiao-Jing Zhao Heng Wang Zi-Han Guo Kai Jin yang Liu Bin-Hui Li Department of Ophthalmology the Fifth Affiliated HospitalSun Yat-sen UniversityZhuhai 519000Guangdong ProvinceChina Department of Ophthalmology Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical UniversityHangzhou 310006Zhejiang ProvinceChina Eye Institute of xiamen University Fujian Provincial Key Laboratory of Ophthalmology and Visual ScienceSchool of MedicineXiamen UniversityXiamen 361005Fujian ProvinceChina

●AIM:To evaluate the role of semaphorin 7A(Sema7A)and its associated regulatory mechanisms in modulating the barrier function of cultured human corneal epithelial cells(HCEs).●METHODS:Barrier models of HCEs were treated with recombinant human Sema7A at concentrations of 0,125,250,or 500 ng/mL for 24,48,or 72h in *** electrical resistance(TEER)as well as Dextran-fluorescein isothiocyanate(FITC)permeability assays were conducted to assess barrier *** quantify tight junctions(TJs)such as occludin and zonula occludens-1(ZO-1)at the mRNA level,reverse transcriptionpolymerase chain reaction(RT-PCR)analysis was *** was used to examine the activity of the nuclear factor-kappa B(NF-κB)signaling pathway and the production of TJs *** analyses were employed to localize the ***-linked immunosorbent assay(ELISA)and RT-PCR were utilized to observe changes in interleukin(IL)-1β*** investigate the role of NF-κB signaling activation and IL^(-1)βin Sema7A’s anti-barrier mechanism,we employed 0.1μmol/L IκB kinase 2(IKK2)inhibitor IV or 500 ng/mL IL^(-1)receptor(IL-1R)antagonist.●RESULTS:Treatment with Sema7A resulted in decreased TEER and increased permeability of Dextran-FITC in HCEs through down-regulating mRNA and protein levels of TJs in a time-and dose-dependent manner,as well as altering the localization of ***,Sema7A stimulated the activation of inhibitor of kappa B alpha(IκBα)and expression of IL-1β.The anti-barrier function of Sema7A was significantly suppressed by treatment with IKK2 inhibitor IV or IL-1R antagonists.●CONCLUSION:Sema7A disrupts barrier function through its influence on NF-κB-mediated expression of TJ proteins,as well as the expression of IL-1β.These findings suggest that Sema7A could be a potential therapeutic target for the diseases in corneal epithelium.

关键词： human corneal epithelial barrier function transepithelial electrical resistance zonula occludens-1 occludin nuclear factor-kappa B

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A Neural-network-based Alternative Scheme to Include Nonhydrostatic Processes in an Atmospheric Dynamical Core

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Advances in Atmospheric Sciences 2024年第6期41卷 1083-1099,I0002,I0003页

作者： yang xia Bin WANG Lijuan LI Li LIU Jianghao LI Li DONG Shiming XU Yiyuan LI Wenwen xia Wenyu HUANG Juanjuan LIU Yong WANG Hongbo LIU Ye PU Yujun HE Kun xia Ministry of Education Key Laboratory for Earth System Modeling and Department of Earth System ScienceTsinghua UniversityBeijing 100084China State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Innovation Group 311020008 Southern Marine Science and Engineering Guangdong LaboratoryZhuhai 519000China Shanghai Ecological Forecasting and Remote Sensing Center Shanghai 200030China Key Laboratory of Earth System Modeling and Prediction China Meteorological AdministrationBeijing 100081China College of Ocean Sciences University of Chinese Academy of SciencesBeijing 100049China

Here,a nonhydrostatic alternative scheme(NAS)is proposed for the grey zone where the nonhydrostatic impact on the atmosphere is evident but not large enough to justify the necessity to include an implicit nonhydrostatic solver in an atmospheric dynamical *** NAS is designed to replace this solver,which can be incorporated into any hydrostatic models so that existing well-developed hydrostatic models can effectively serve for a longer *** advances in machine learning(ML)provide a potential tool for capturing the main complicated nonlinear-nonhydrostatic *** this study,an ML approach called a neural network(NN)was adopted to select leading input features and develop the *** NNs were trained and evaluated with 12-day simulation results of dry baroclinic-wave tests by the Weather Research and Forecasting(WRF)*** forward time difference of the nonhydrostatic tendency was used as the target variable,and the five selected features were the nonhydrostatic tendency at the last time step,and four hydrostatic variables at the current step including geopotential height,pressure in two different forms,and potential temperature,***,a practical NAS was developed with these features and trained layer by layer at a 20-km horizontal resolution,which can accurately reproduce the temporal variation and vertical distribution of the nonhydrostatic *** by the NN-based NAS,the improved hydrostatic solver at different horizontal resolutions can run stably for at least one month and effectively reduce most of the nonhydrostatic errors in terms of system bias,anomaly root-mean-square error,and the error of the wave spatial pattern,which proves the feasibility and superiority of this scheme.

关键词： neural network nonhydrostatic alternative scheme atmospheric model dynamical core

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Morphological disruption and visual tuning alterations in the primary visual cortex in glaucoma(DBA/2J)mice

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Neural Regeneration Research 2024年第1期19卷 220-225页

作者： Yin yang Zhaoxi yang Maoxia Lv Ang Jia Junjun Li Baitao Liao Jing’an Chen Zhengzheng Wu Yi Shi yang xia Dezhong Yao Ke Chen Department of Ophthalmology Sichuan Provincial People’s HospitalMedical SchoolUniversity of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina The Clinical Hospital of Chengdu Brain Science Institute MOE Key Lab for NeuroInformationSchool of Life Science and TechnologyUniversity of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina Research Unit of NeuroInformation Chinese Academy of Medical SciencesChengduSichuan ProvinceChina Institute of Basic Medical Sciences Chinese Academy of Medical Sciences School of Basic Medicine Peking Union Medical CollegeBeijingChina Health Management Center Sichuan Provincial Key Laboratory for Human Disease Gene StudySichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina Research Unit for Blindness Prevention of Chinese Academy of Medical Sciences(2019RU026) Sichuan Academy of Medical SciencesChengduSichuan ProvinceChina School of Electrical Engineering Zhengzhou UniversityZhengzhouHenan ProvinceChina

Glaucoma is a leading cause of irreve rsible blindness wo rldwide,and previous studies have shown that,in addition to affecting the eyes,it also causes abnormalities in the ***,it is not yet clear how the primary visual cortex(V1)is altered in *** study used DBA/2J mice as a model for spontaneous secondary *** aim of the study was to compare the electrophysiological and histomorphological chara cteristics of neurons in the V1between 9-month-old DBA/2J mice and age-matched C57BL/6J *** conducted single-unit recordings in the V1 of light-anesthetized mice to measure the visually induced responses,including single-unit spiking and gamma band *** morphology of layerⅡ/Ⅲneurons was determined by neuronal nuclear antigen staining and Nissl staining of brain tissue ***-seven neurons from eight DBA/2J mice and eighty-one neurons from eight C57BL/6J mice were *** with the C57BL/6J group,V1 neurons in the DBA/2J group exhibited weaker visual tuning and impaired spatial *** r,fewer neuro ns were observed in the V1 of DBA/2J mice compared with C57BL/6J *** findings suggest that DBA/2J mice have fewer neurons in the VI compared with C57BL/6J mice,and that these neurons have impaired visual *** findings provide a better understanding of the pathological changes that occur in V1 neuron function and morphology in the DBA/2J mouse *** study might offer some innovative perspectives regarding the treatment of glaucoma.

关键词： DBA/2J degeneration gamma band oscillations glaucoma primary visual cortex(V1) retina single-unit recording tuning curve

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