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World Journal of Cardiology 2024年第10期16卷 611-615页

作者： yan-xi zhang Hai-Sheng Hu Bao-Qing Sun Department of Clinical Laboratory The First Affiliated Hospital of Guangzhou Medical UniversityState Key Laboratory of Respiratory DiseaseNational Center for Respiratory MedicineNational Clinical Research Center for Respiratory DiseaseGuangzhou Institute of Respiratory HealthGuangzhou 510120Guangdong ProvinceChina

We comment on an article by GrubićRotkvićet al published in the recent issue of the World Journal of *** specifically focused on possible factors affecting the therapeutic effectiveness of sodium-dependent glucose transporter inhibitors(SGLT2i)in patients with type 2 diabetes mellitus(T2DM)and their impact on ***2i inhibits SGLT2 in the proximal tubules of the kidneys,lowering blood glucose levels by inhibiting glucose reabsorption by the kidneys and causing excess glucose to be excreted in the *** studies have demonstrated a role of SGLT2i in cardiovascular function in patients with diabetes who take metformin but still have poor glycemic *** addition,SGLT2i has been shown to be effective in anti-apoptosis,weight loss,and cardiovascular ***,it is feasible to treat patients with T2DM with cardiovascular or renal diseases using SGLT2i.

关键词： Sodium-dependent glucose transporter inhibitors Type 2 diabetes mellitus Heart failure Treatment Cardiovascular disease

Fracture morphology and crack mechanism in pure polycrystalline magnesium under tension-compression fatigue testing

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Rare Metals 2020年第2期39卷 162-168页

作者： Li Tan xi-yan zhang Ting xia Guang-Jie Huang Qing Liu College of Materials Science and Engineering Chongqing UniversityChongqing400045China National Engineering Research Centre for Magnesium Alloy Chongqing UniversityChongqing400045China

The fatigue fracture was characterized and the fracture behavior was analyzed,using scanning electron microscope(SEM)and electron back-scattered diffraction(EBSD),the fatigue tests of two strain amplitude at room temperature were 0.5%and 1.0%respectively,and the results showed that the fatigue deformation of different strain amplitude produced two typical fatigue fracture morphology,and when the strain amplitude was 1.0%,fatigue fracture mechanism of AZ31 magnesium alloy induced by{1012}twins,when the strain amplitude is 0.5%,it was induced by{1012}-{1012}double *** the present study,the average thickness of primary twin is^20μm at amplitude of 0.5%and^80μm at amplitude of 1.%.The thickness of{1012}primary twins was large enough to activate{1012}-{1012}secondary twins at a high strain amplitude,while the thickness of{1012}primary twins was too narrow to activate{1012}-{1012}secondary twins at a low strain amplitude.

关键词： Deformation twinning Magnesium Fracture Fatigue

Tartaric acid-assisted co-precipitation synthesis of Er^(3+)-doped Lu_2O_3 nanopowders

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Chinese Chemical Letters 2012年第11期23卷 1299-1302页

作者： Neng Li Wang xi yan zhang Peng He Wang School of Materials Science and Engineering Changchun University of Science and TechnologyChangchun 130022China

Erbium-doped lutetia nanopowders were synthesized by a novel co-precipitation method using tartaric acid as precipitant. The properties of the samples were investigated by Fourier transform infrared spectroscopy （FTIR）, X-ray diffraction （XRD）, TG-DSC, field emission scanning electron microscopy （FE-SEM）, and upconversion luminescence analysis. Pure cubic Lu2Oa nanopowders were directly obtained when the precursor was calcined at 800 ℃ for 2 h, the samples showed strong upconversion luminescence under excitation of 980 nm laser diode.

关键词： Co-precipitation Tartaric acid Erbium-doped lutetia Upconversion

High-precision parallel computing model of solute transport based on GPU acceleration

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Journal of Hydrodynamics 2024年第1期36卷 202-212页

作者： Shang-hong zhang Rong-qi zhang Wen-da Li xi-yan yang yang Zhou School of Water Resources and Hydropower Engineering North China Electric Power UniversityBeijing102206China Hubei Key Laboratory of Intelligent yangtze and Hydroelectric Science China Yangtze Power Co.Ltd.Yichang443133China

The scenario simulation analysis of water environmental emergencies is very important for risk prevention and control,and emergency *** quickly and accurately simulate the transport and diffusion process of high-intensity pollutants during sudden environmental water pollution events,in this study,a high-precision pollution transport and diffusion model for unstructured grids based on Compute Unified Device Architecture(CUDA)is *** finite volume method of a total variation diminishing limiter with the Kong proposed r-factor is used to reduce numerical diffusion and oscillation errors in the simulation of pollutants under sharp concentration conditions,and graphics processing unit acceleration technology is used to improve computational *** advection diffusion process of the model is verified numerically using two benchmark cases,and the efficiency of the model is evaluated using an engineering *** results demonstrate that the model perform well in the simulation of material transport in the presence of sharp ***,it has high computational *** acceleration ratio is 46 times the single-thread acceleration effect of the original *** efficiency of the accelerated model meet the requirements of an engineering application,and the rapid early warning and assessment of water pollution accidents is achieved.

关键词： Pollution transport and diffusion model parallel computing Compute Unified Device Architecture(CUDA) pollution event

Epidemiological characteristics of childhood obesity in eastern China, 2017-2019

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World Journal of Pediatrics 2019年第4期15卷 412-414页

作者： xi-yan zhang Wen-Yi yang Jie yang yan Wang Yao xiang Liu-Wei Gao Feng-Yun zhang Yong-Lin Zhou Department of Child and Adolescent Health Promotion Jiangsu Provincial Center for Disease Control and PreventionNo.172 Jiangsu RoadNanjing 210009China Public Health Research Institute of Jiangsu Province NanjingChina School of Public Health Southeast UniversityNanjingChina

Childhood obesity has becoming an increasing concern in many countries including China [1-3].Located in the eastern China,Jiangsu Province is one of the developed regions in China and is also facing this problem.

关键词： Childhood obesity Epidemiology Jiangsu province Risk factors

Preparation and Characterization of Three-dimensionally Ordered Crystalline Macroporous CeO_2

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Chinese Chemical Letters 2005年第8期16卷 1109-1112页

作者： xi yan zhang Tong Wen WANG Wen Qing JIANG Di WU Ling LIU Ai Hong DUAN Department of Chemistry Yunnan Normal University Kunming 650092

A stable 3DOM CeO2 with well-defined inverse opal microstructure and crystalline walls structure has been successfully synthesized by application of three-dimensional order PMMA beads as templates. Structural feature ... 详细信息

关键词： 3DOM CeO2 PMMA colloidal crystal template crystalline wall.

THE EFFECT OF OIL CAVITY DEPTH ON TEMPERATURE FIELD IN HEAVY HYDROSTATIC THRUST BEARING

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Journal of Hydrodynamics 2011年第5期23卷 676-680页

作者： SHAO Jun-peng DAI Chun-xi zhang yan-qin YU xiao-dong XU xiao-qiu WANG Yun-fei College of Mechanical and Power Engineering Harbin UniverSity of Science and Technology Harbin150080 China

For a heavy hydrostatic bearing with a high linear velocity, the results of numerical calculations often differ from practical conditions if the viscosity is considered as constant. In this article, the influence of the oil cavity depth on the temperature field in the heavy hydrostatic bearing is discussed in the context of variable viscosity. The viscosity-temperature relations for the gap oil film are first established by fitting B-Spline curves, then, numerical calculations for the temperature field in the heavy hydrostatic bearing of different oil cavity depths are carried out based on Finite Volume Method （FVM） under the same rotating speed, and the influence of the oil cavity depth on the temperature distribution in the gap oil film of the hydrostatic bearing is discussed. The results of numerical calculations provide the temperature distribution state inside the hydrostatic bearing, which would help the selection and the design of hydrostatic bearings in engineering practice.

关键词： hydrostatic thrust bearing viscosity-temperature characteristic Finite Volume Method (FVM) temperature field

Efficacy of cognitive-behavioral therapy combined with habit reversal training on anxiety disorders in children with Tourette’s syndrome

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World Journal of Psychiatry 2024年第7期14卷 999-1008页

作者： yan-Zhen Wang xi zhang xin-Min Han Department of Rehabilitation Children’s Hospital of ShanxiTaiyuan 030012Shanxi ProvinceChina Department of Pediatrics The Affiliated Hospital of Nanjing University of Chinese MedicineNanjing 210029Jiangsu ProvinceChina

BACKGROUND Cognitive-behavioral therapy(CBT)and habit reversal training(HRT)have shown application potential in addressing tic symptoms and comorbid psychiatric *** their theoretical potential,empirical evidence on their combined efficacy remains *** To evaluate the efficacy of CBT combined with HRT on anxiety disorders in children with Tourette’s syndrome(TS).METHODS Clinical data of children with TS admitted to our hospital from January 2022 to June 2023 were collected,and the patients were grouped into the conventional therapy(control)group and the CBT combined with HRT *** charac-teristics,anxiety scores,tic severity scores,treatment adherence,and parental satisfaction were *** analysis was performed using t-tests,chi-square tests,and correlation *** A total of 136 patients,including 65 patients in the control group and 71 patients in the CBT combined with HRT group,were *** CBT combined with HRT group showed remarkable improvements compared with the control ***-intervention assessment revealed a decrease in anxiety scores from 63.52±1.81 to 40.53±1.64(t=2.022,P=0.045),and the Yale Global Tic Severity Scale total score decreased from 22.14±5.67 to 16.28±4.91(t=2.288,P=0.024).Treatment adherence was significantly higher in the CBT combined with HRT group(85.47±7.62%)compared with the control group(82.32±6.54%;t=2.596,P=0.010).Parental satisfaction scores were also higher in the CBT combined with HRT group(8.69±1.77)compared with the control group(7.87±1.92;t=2.592,P=0.011).CONCLUSION This study demonstrates that CBT combined with HRT significantly reduces anxiety symptoms and tic severity in children with TS,with higher treatment adherence and parental *** findings support the potential application of this comprehensive therapeutic approach for TS treatment.

关键词： Tourette's syndrome Cognitive-behavioral therapy Habit reversal training Efficacy evaluation Anxiety disorders

A review of the neurotransmitter system associated with cognitive function of the cerebellum in Parkinson's disease

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Neural Regeneration Research 2024年第2期19卷 324-330页

作者： xi Chen Yuhu zhang Department of Neurology Guangdong Neuroscience InstituteGuangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences)Southern Medical UniversityGuangzhouGuangdong ProvinceChina Shantou University Medical College ShantouGuangdong ProvinceChina

The dichotomized brain system is a concept that was generalized from the‘dual syndrome hypothesis’to explain the heterogeneity of cognitive impairment,in which anterior and posterior brain systems are independent but partially *** dopaminergic system acts on the anterior brain and is responsible for executive function,working memory,and *** contrast,the cholinergic system acts on the posterior brain and is responsible for semantic fluency and visuospatial *** from dopaminergic/cholinergic imaging or functional neuroimaging has shed significant insight relating to the involvement of the cerebellum in the cognitive process of patients with Parkinson’s *** research has reported evidence that the cerebellum receives both dopaminergic and cholinergic ***,whether these two neurotransmitter systems are associated with cognitive function has yet to be fully ***,the precise role of the cerebellum in patients with Parkinson’s disease and cognitive impairment remains ***,in this review,we summarize the cerebellar dopaminergic and cholinergic projections and their relationships with cognition,as reported by previous studies,and investigated the role of the cerebellum in patients with Parkinson’s disease and cognitive impairment,as determined by functional *** findings will help us to understand the role of the cerebellum in the mechanisms underlying cognitive impairment in Parkinson’s disease.

关键词： anterior brain system cerebellum cholinergic cognitive impairment dopaminergic dual syndrome hypothesis neuroimage neurotransmitter Parkinson’s disease posterior brain system therapeutic targets

High-Order DG Schemes with Subcell Limiting Strategies for Simulations of Shocks,Vortices and Sound Waves in Materials Science Problems

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Fluid Dynamics & Materials Processing 2024年第10期20卷 2183-2204页

作者： Zhenhua Jiang xi Deng xin zhang Chao yan Feng xiao Jian Yu College of Aeronautics Science and Engineering Beijing University of Aeronautics and AstronauticsBeijing100191China Department of Chemical Engineering Imperial College LondonLondonSW72AZUK Department of Engineering University of CambridgeCambridgeCB21PZUK Department of Mechanical Engineering Tokyo Institute of TechnologyTokyo152-8550Japan

Shock waves,characterized by abrupt changes in pressure,temperature,and density,play a significant role in various materials science processes involving *** high-energy phenomena are utilized across multiple fields and applications to achieve unique material properties and facilitate advanced manufacturing *** simulations of these phenomena require numerical schemes that can represent shock waves without spurious oscillations and simultaneously capture acoustic waves for a wide range of wavelength *** work suggests a high-order discontinuous Galerkin(DG)method with a finite volume(FV)subcell limiting strategies to achieve better subcell resolution and lower numerical diffusion *** switching to the FV discretization on an embedded sub-cell grid,the method displays advantages with respect to both DG accuracy and FV shock-capturing *** FV scheme utilizes a class of high-fidelity schemes that are built upon the boundary variation diminishing(BVD)reconstruction *** method is therefore able to resolve discontinuities and multi-scale structures on the subcell level,while preserving the favorable properties of the high-order DG *** have tested the present DG method up to the 6th-order accuracy for both smooth and discontinuous noise problems.

关键词： Discontinuous Galerkin finite volume subcell limiting shock associated noise computational aeroacoustics