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Optimal Test Points Selection Based on Multi-Objective Genetic Algorithm

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Journal of Electronic Science and Technology of China 2009年第4期7卷 317-321页

作者： yong zhang xi-xiang chen guan-jun liu jing qiu Shu-Ming Yang College of Mechatronical Engineering and Automation National University of Defense Technology Changsha 410073 China

A new approach to select anoptimal set of test points is proposed. The described method uses fault-wise table and multi-objective genetic algorithm to find the optimal set of test points. First, the fault-wise table is constructed whose entries are measurements associated with faults and test points. The selection of optimal test points is transformed to the selection of the columns that isolate the rows of the table. Then, four objectives are described according to practical test requirements. The multi-objective genetic algorithm is explained. Finally, the presented approach is illustrated by a practical example. The results indicate that the proposed method can efficiently and accurately find the optimal set of test points and is practical for large scale systems.

关键词： Design for testability multi-objective genetic algorithm system testing test points selection.

Implications on the origin of cosmic rays in light of 10 TV spectral softenings

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Frontiers of physics 2020年第2期15卷 101-109,F0004页

作者： Cliuan Yue Peng-xiong Ma Qiang Yuan Yi-Zhong Fan Zhan-Fang chen Ming-Yang Cui Hao-Ting Dai Tie-Kuang Dong xiaoyuan Huang Wei Jiang Shi-jun Lei xiang Li cheng-Ming liu Hao liu Yang liu Chuan-Ning Luo Xu Pan Wen-xi Peng Rui Qiao Yi-Feng Wei Li-Bo Wu Zhi-Hui Xu Zun-Lei Xu guan-Wen Yuan jing-jing Zang Ya-Peng zhang yong-Jie zhang Yun-Long zhang Key Laboratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210033China School of Astronomy and Space Science University of Science and Technology of ChinaHefei 230026China Center for High Energy Physics Peking UniversityBeijing 100871China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China Institute of Modem Physics Chinese Academy of SciencesLanzhou 730000China

Precise measurements of the energy spectra of cosmic rays(CRs)show various kinds of features deviating from single power-laws,which give very interesting and important implications on their origin and *** measurements from a few balloon and space experiments indicate the existence of spectral softenings around 10 TV for protons(and probably also for Helium nuclei).Very recently,the DArk Matter Particle Explorer(DAMPE)measurement about the proton spectrum clearly reveals such a softening with a high *** we study the implications of these new measurements,as well as the groundbased indirect measurements,on the origin of *** find that a single component of CRs fails to fit the spectral softening and the air shower experiment data *** the framework of multiple components,we discuss two possible scenarios,the multiple source population scenario and the background plus nearby source *** scenarios give reasonable fits to the wide-band data from TeV to 100 PeV *** the anisotropy observations,the nearby source model is favored.

关键词： cosmic rays

The Large Sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST)

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Research in Astronomy and Astrophysics 2012年第9期12卷 1197-1242页

作者： xiang-Qun Cui yong-Heng Zhao Yao-Quan Chu Guo-Ping Li Qi Li Li-Ping zhang Hong-jun Su Zheng-qiu Yao Ya-Nan Wang xiao-Zheng xing xin-Nan Li yong-Tian Zhu Gang Wang Bo-Zhong Gu A-Li Luo xin-Qi Xu Zhen-Chao zhang Gen-Rong liu Hao-Tong zhang De-Hua Yang Shu-Yun Cao Hai-Yuan chen Jian-jun chen Kun-xin chen Ying chen Jia-Ru Chu Lei Feng Xue-Fei Gong yong-Hui Hou Hong-Zhuan Hu Ning-Sheng Hu Zhong-Wen Hu Lei Jia Fang-Hua Jiang xiang Jiang Zi-Bo Jiang Ge Jin Ai-Hua Li Yan Li Ye-Ping Li guan-Qunliu Zhi-Gang liu Huo-Ming Shi Zheng-Hong Tang Qing-Sheng Tao xiang-Yan Yuan Chao Zhai jing zhang Yan-xia zhang yong zhang Ming Zhao Fang Zhou Guo-Hua Zhou Jie Zhu Si-cheng Zou National Astronomical Observatories Chinese Academy of Sciences Beijing 100012 China yzhao @ *** Nanjing Institute of Astronomical Optics and Technology National Astronomical ObservatoriesChinese Academy of Sciences Nanjing 210042 China University of Science and Tecfinologyof China Hefei 230026 China Shanghai Astronomical Observatory Chinese Academy of Sciences Shanghai 200030 China Institute of Architecture Design and Research Chinese Academy of Sciences Beijing 100190China

The Large Sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST, also called the Guo Shou jing Telescope) is a special reflecting Schmidt telescope. LAMOST’s special design allows both a large aperture (effective aperture of 3.6 m–4.9 m) and a wide field of view (FOV) (5°). It has an innovative active reflecting Schmidt configuration which continuously changes the mirror’s surface that adjusts during the observation process and combines thin deformable mirror active optics with segmented active optics. Its primary mirror (6.67m×6.05 m) and active Schmidt mirror (5.74m×4.40 m) are both segmented, and composed of 37 and 24 hexagonal sub-mirrors respectively. By using a parallel controllable fiber positioning technique, the focal surface of 1.75 m in diameter can accommodate 4000 optical fibers. Also, LAMOST has 16 spectrographs with 32 CCD cameras. LAMOST will be the telescope with the highest rate of spectral acquisition. As a national large scientific project, the LAMOST project was formally proposed in 1996, and approved by the Chinese government in 1997. The construction started in 2001, was completed in 2008 and passed the official acceptance in june 2009. The LAMOST pilot survey was started in October 2011 and the spectroscopic survey will launch in September 2012. Up to now, LAMOST has released more than 480 000 spectra of objects. LAMOST will make an important contribution to the study of the large-scale structure of the Universe, structure and evolution of the Galaxy, and cross-identification of multiwaveband properties in celestial objects.

关键词： techniques: wide field telescope - active optics - multi fiber - spectroscopy survey - data reduction

10B-doped MCP detector developed for neutron resonance imaging at Back-n white neutron source

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Nuclear Science and Techniques 2024年第8期35卷 58-68页

作者： Qiang Li Li‑Jiao Wang jing‑Yu Tang xiang‑Biao qiu Zhen chen Mao‑Yuan Zhao Chang‑jun Ning Kai Pan Wei Xu Tao Li Su‑Peng Lu Han Yi Rui‑Rui Fan Chang‑Qing Feng Rong zhang xiao‑Yang Sun Qi An Hao‑Fan Bai Jiang‑Bo Bai Jie Bao Ping Cao Qi‑Ping chen yong‑Hao chen Zeng‑Qi Cui An‑Chuan Fan Fan‑Zhen Feng Min‑Hao Gu Chang‑Cai Han Zi‑Jie Han Guo‑Zhu He yong‑cheng He Yang Hong Yi‑Wei Hu Han‑xiong Huang Wei Jiang Zhi‑Jie Jiang Zheng‑Yao Jin Ling Kang Bo Li Gong Li xiao Li Yang Li Jie liu Rong liu Shu‑Bin liu Yi‑Na liu guang‑Yuan Luan Jie Ren Zhi‑Zhou Ren xi‑Chao Ruan Zhao‑Hui Song Kang Sun Zhi‑xin Tan Sheng‑Da Tang Jin‑cheng Wang Peng‑cheng Wang Zhao‑Hui Wang Zhong‑Wei Wen xiao‑guang Wu Xuan Wu Cong xia yong‑Ji Yu Guo‑Hui zhang Hang‑Chang zhang Lin‑Hao zhang Qi‑Wei zhang xian‑Peng zhang Yu‑Liang zhang Yue zhang Zhi‑yong zhang Zhi‑Hao Zhou Ke‑jun Zhu Chong Zou Institute of High Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China State Key Laboratory of Particle Detection and Electronics Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Dongguan Songshan Lake Future School Dongguan 523808China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230027China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China North Night Vision Science and Technology(Nanjing)Research Institute Co.Ltd Nanjing 211106China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Institute of Modern Physics Fudan UniversityShanghai 200433China Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China China Academy of Engineering Physics Institute of Nuclear Physics and ChemistryMianyang 621900China USTC archaeometry lab University of Science and Technology of ChinaHefei 230026China Northwest Institute of Nuclear Technology Xi’an 710024China University of Chinese Academy of Sciences Beijing 100049China China Shipbuilding Trading Co. LtdBeijing 100044China

Neutron resonance imaging(NRI)has recently emerged as an appealing technique for neutron *** complexity surpasses that of conventional transmission imaging,as it requires a high demand for both a neutron source and ***,the progression of NRI technology has been sluggish since its inception in the 1980s,particularly considering the limited studies analyzing the neutron energy range above *** white neutron source(Back-n)at the China Spallation Neutron Source(CSNS)provides favorable beam conditions for the development of the NRI technique over a wide neutron energy range from eV to ***-sensitive microchannel plates(MCP)have emerged as a cutting-edge tool in the field of neutron detection owing to their high temporal and spatial resolutions,high detection efficiency,and low *** this study,we report the development of a 10B-doped MCP detector,along with its associated electronics,data processing system,and NRI experiments at the *** heavy elements such as gold,silver,tungsten,and indium can be easily identified in the transmission images by their characteristic resonance peaks in the 1–100 eV energy range;the more difficult medium-weight elements such as iron,copper,and aluminum with resonance peaks in the 1–100 keV energy range can also be *** particular,results in the neutron energy range of dozens of keV(Aluminum)are reported here for the first time.

关键词： Neutron resonance imaging 10B doped MCP detector White neutron source Sample nuclide identification

Study of the response of 10B-doped MCP to wide-energy range neutrons from eV to MeV

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Nuclear Science and Techniques 2024年第8期35卷 132-141页

作者： Qiang Li Li‑Jiao Wang xiang‑Biao qiu jing‑Wen Li Wei Xu Tao Li Ze‑Bin Lin Chang‑jun Ning yong‑Hao chen Rui‑Rui Fan Kang Sun jing‑Yu Tang Rong zhang Han‑Tao jing Bo Mei Qi An Hao‑Fan Bai Jiang‑Bo Bai Jie Bao Ping Cao Qi‑Ping chen Zhen chen Zeng‑Qi Cui An‑Chuan Fan Chang‑Qing Feng Fan‑Zhen Feng Ke‑Qing Gao Min‑Hao Gu Chang‑Cai Han Zi‑Jie Han Guo‑Zhu He yong‑cheng He Yang Hong Yi‑Wei Hu Han‑xiong Huang Wei‑Hua Jia Hao‑Yu Jiang Wei Jiang Zhi‑Jie Jiang Zheng‑Yao Jin Ling Kang Bo Li Chao Li Gong Li Jia‑Wen Li xiao Li Yang Li Jie liu Rong liu Shu‑Bin liu guang‑Yuan Luan Bin‑Bin Qi Jie Ren Zhi‑Zhou Ren xi‑Chao Ruan Zhao‑Hui Song Zhi‑xin Tan Sheng‑Da Tang Peng‑cheng Wang Zhao‑Hui Wang Zhong‑Wei Wen xiao‑guang Wu Xuan Wu Li‑Kun xie Yi‑Wei Yang Han Yi yong‑Ji Yu Guo‑Hui zhang Lin‑Hao zhang Mo‑Han zhang Qi‑Wei zhang xian‑Peng zhang Yu‑Liang zhang Yue zhang Zhi‑yong zhang Mao‑Yuan Zhao Lu‑Ping Zhou Zhi‑Hao Zhou Ke‑jun Zhu Institute of High Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China State Key Laboratory of Particle Detection and Electronics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China Dongguan Songshan Lake Future School Dongguan 523808China North Night Vision Science&Technology(Nanjing)Research Institute Co.Ltd. Nanjing 211106China Sino‑French Institute of Nuclear Engineering and Technology Sun Yat-sen UniversityZhuhai 519082China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230027China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Institute of Nuclear Physics and Chemistry China Academy of Engineering PhysicsMianyang 621900China Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China USTC Archaeometry Lab University of Science and Technology of ChinaHefei 230026China Northwest Institute of Nuclear Technology Xi’an 710024China University of Chinese Academy of Sciences Beijing 100049China

Neutron-sensitive microchannel plates(nMCPs)have applications in neutron detection,including energy spectrum measurements,neutron-induced cross sections,and neutron imaging.10B-doped MCPs(B-MCPs)have attracted significant attention owing to their potential for exhibiting a high neutron detection efficiency over a large neutron energy *** spatial and temporal resolutions are useful for neutron energy-resolved ***,their practical applications still face many technical *** this study,a B-MCP with 10 mol%10B was tested for its response to wide-energy neutrons from eV to MeV at the Back-n white neutron source at the China Spallation Neutron *** neutron detection efficiency was calibrated at 1 eV,which is approximately 300 times that of an ordinary MCP and indicates the success of 10 B *** factors that caused the reduction in the detection efficiency were simulated and *** neutron energy spectrum obtained using B-MCP was compared with that obtained by other measurement methods,and showed very good consistency for neutron energies below tens of *** response is more complicated at higher neutron energy,at which point the elastic and nonelastic reactions of all nuclides of B-MCP gradually become *** is beneficial for the detection of neutrons,as it compensates for the detection efficiency of B-MCP for high-energy neutrons.

关键词： Neutron radiation image 10B-doped MCP Neutron response Wide-energy range neutrons

The first data release(DR1) of the LAMOST regular survey

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Research in Astronomy and Astrophysics 2015年第8期15卷 1095-1124页

作者： A-Li Luo yong-Heng Zhao Gang Zhao Li-Cai Deng xiao-Wei liu Yi-Peng jing Gang Wang Hao-Tong zhang Jian-Rong Shi xiang-Qun Cui Yao-Quan Chu Guo-Ping Li Zhong-Rui Bai Yue Wu Yan Cai Shu-Yun Cao Zi-Huang Cao Jeffrey L.Carlin Hai-Yuan chen Jian-jun chen Kun-xin chen Li chen Xue-Lei chen xiao-Yan chen Ying chen Norbert Christlieb Jia-Ru Chu chen-Zhou Cui Yi-Qiao Dong Bing Du Dong-Wei Fan Lei Feng Jian-Ning Fu Peng Gao Xue-Fei Gong Bo-Zhong Gu Yan-xin Guo Zhan-Wen Han Bo-Liang He Jin-Liang Hou yong-Hui Hou Wen Hou Hong-Zhuan Hu Ning-Sheng Hu Zhong-Wen Hu Zhi-Ying Huo Lei Jia Fang-Hua Jiang xiang Jiang Zhi-Bo Jiang Ge Jin xiao Kong Xu Kong Ya-Juan Lei Ai-Hua Li Chang-Hua Li guang-Wei Li Hai-Ning Li Jian Li Qi Li Shuang Li Sha-Sha Li xin-Nan Li Yan Li Yin-Bi Li Ye-Ping Li Yuan Liang Chien-cheng Lin Chao liu Gen-Rong liu guan-Qun liu Zhi-Gang liu Wen-Zhi Lu Yu Luo Yin-Dun Mao Heidi Newberg Ji-jun Ni Zhao-xiang Qi yong-jun Qi Shi-Yin Shen Huo-Ming Shi jing Song Yi-Han Song Ding-Qiang Su Hong-jun Su Zheng-Hong Tang Qing-Sheng Tao Yuan Tian Dan Wang Da-Qi Wang Feng-Fei Wang Guo-Min Wang Hai Wang Hong-Chi Wang Jian Wang Jia-Ning Wang Jian-Ling Wang Jian-Ping Wang jun-xian Wang Lei Wang Meng-xin Wang Shou-guan Wang Shu-Qing Wang xia Wang Ya-Nan Wang You Wang Yue-Fei Wang You-Fen Wang Peng Wei Ming-Zhi Wei Hong Wu Ke-Fei Wu Xue-Bing Wu Yu-Zhong Wu xiao-Zheng xing Ling-Zhe Xu xin-Qi Xu Yan Xu Tai-Sheng Yan De-Hua Yang Hai-Feng Yang Hui-Qin Yang Ming Yang Zheng-qiu Yao yong Yu Hui Yuan Hai-Bo Yuan Hai-Long Yuan Wei-Min Yuan Chao Zhai En-Peng zhang Hua-Wei zhang Jian-Nan zhang Li-Pin zhang Wei zhang yong zhang Yan-xia zhang Zheng-Chao zhang Ming Zhao Fang Zhou Xu Zhou Jie Zhu yong-Tian Zhu Si-cheng Zou Fang Zuo National Astronomical Observatories Chinese Academy of Sciences Department of Astronomy Peking University Shanghai Astronomical Observatory Chinese Academy of Sciences Nanjing Institute of Astronomical Optics & Technology National Astronomical ObservatoriesChinese Academy of Sciences University of Science and Technology of China Department of Physics Applied Physics and AstronomyRensselaer Polytechnic InstituteTroyNY 12180USA Department of Physics and Astronomy Earlham CollegeRichmondIN 47374USA Universitt Heidelberg Zentrum für AstronomieLandessternwarteKnigstuhl 1269117 HeidelbergGermany Department of Astronomy Beijing Normal University Yunnan Observatories Chinese Academy of Sciences Purple Mountain Observatory Chinese Academy of Sciences

The Large sky Area Multi-Object Fiber Spectroscopic Telescope（LAMOST） general survey is a spectroscopic survey that will eventually cover approximately half of the celestial sphere and collect 10 million spectra of stars, galaxies and QSOs. Objects in both the pilot survey and the first year regular survey are included in the LAMOST DR1. The pilot survey started in October 2011 and ended in june 2012, and the data have been released to the public as the LAMOST Pilot Data Release in August 2012. The regular survey started in September 2012, and completed its first year of operation in june 2013. The LAMOST DR1 includes a total of 1202 plates containing 2 955 336 spectra, of which 1 790 879 spectra have observed signalto-noise ratio（SNR） ≥ 10. All data with SNR ≥ 2 are formally released as LAMOST DR1 under the LAMOST data policy. This data release contains a total of 2 204 696 spectra, of which 1 944 329 are stellar spectra, 12 082 are galaxy spectra and 5017 are quasars. The DR1 not only includes spectra, but also three stellar catalogs with measured parameters： late A,FGK-type stars with high quality spectra（1 061 918 entries）, A-type stars（100 073 entries）, and M-type stars（121 522 entries）. This paper introduces the survey design, the observational and instrumental limitations, data reduction and analysis, and some caveats. A description of the FITS structure of spectral files and parameter catalogs is also provided.

关键词： techniques: spectroscopic survey—data release—catalog

Management of granulomatous lobular mastitis: an international multidisciplinary consensus(2021 edition)

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Military Medical Research 2022年第4期9卷 389-403页

作者： Qian-Qian Yuan Shu-Yuan xiao Omar Farouk Yu-Tang Du Fereshte Sheybani Qing Ting Tan Sami Akbulut Kenan Cetin Afsaneh Alikhassi Rami Jalal Yaghan Irmak Durur-Subasi Fatih Altintoprak Tae Ik Eom Fatih Alper Mustafa Hasbahceci David Martínez-Ramos Pelin Seher Oztekin Ava Kwong Cedric W.Pluguez-Turul Kirstyn EBrownson Shirish Chandanwale Mehran Habib liu-Yi Lan Rui Zhou xian-Tao Zeng Jiao Bai jun-Wen Bai Qiong-Rong chen xing chen xiao-Ming Zha Wen-Jie Dai Zhi-jun Dai Qin-Yu Feng Qing-jun Gao Run-Fang Gao Bao-San Han Jin-Xuan Hou Wei Hou Hai-Ying Liao Hong Luo Zheng-Ren liu jing-Hua Lu Bin Luo xiao-Peng Ma jun Qian Jian-yong Qin Wei Wei Gang Wei Li-Ying Xu Hui-Chao Xue Hua-Wei Yang Wei-Ge Yang Chao-Jie zhang Fan zhang guan-xin zhang Shao-Kun zhang Shu-Qun zhang Ye-Qiang zhang Yue-Peng zhang Sheng-Chu zhang Dai-Wei Zhao xiang-Min Zheng Le-Wei Zheng Gao-Ran Xu Wen-Bo Zhou Gao-Song Wu Department of Thyroid and Breast Surgery Zhongnan Hospital of Wuhan UniversityWuhan430071China Department of Pathology University of Chicago Pritzker School of MedicineChicagoIL60637USA Department of Surgical Oncology and Breast Surgery Oncology CenterFaculty of MedicineMansoura UniversityMansoura35516Egypt Department of Breast Surgery Beijing University of Chinese MedicineBeijing100700China Department of Infectious Diseases and Tropical Medicine Faculty of MedicineMashhad University of Medical SciencesMashhad***Iran Breast Department KK Women’s and Children’s Hospital100 Bukit Timah RoadSingapore229899Singapore Department of Surgery Department of Public HealthDepartment of BiostatisticsBioinformatics and Medical InformaticsInonu University Faculty of Medicine44280MalatyaTurkey Department of General Surgery Faculty of MedicineÇanakkale Onsekiz Mart University17020ÇanakkaleTurkey Department of Radiology Cancer InstituteImam Khomeini HospitalTehran University of Medical SciencesTehran***Iran Department of Surgery College of Medicine and Medical SciencesArabian Gulf University-BahrainManama26671Bahrain Department of Radiology International Faculty of MedicineIstanbul Medipol University34810IstanbulTurkey Department of General Surgery Faculty of MedicineSakarya University54050SakaryaTurkey Department of Surgery HiU Clinic170Gwongwang-roPaldal-guSuwon16488Korea Department of Radiology Faculty of MedicineAtaturk University25240ErzurumTurkey Academic Support and Education Center Hırkai Serif DistrictKececi Cesmesi StrDoktorlar BuildingB/734091IstanbulTurkey Department of General and Digestive Surgery Hospital General CastellonAvda Benicassim S/N12812004CastellónSpain Radiology Department Ankara Training and Research Hospital305018AnkaraTurkey Department of Surgery The University of Hong KongChina The University of Hong Kong-Shenzhen Hospital Shenzhen518053China University of Miami Health System and Miller School of Medicine 1475 NW 12th AvenueM

Granulomatous lobular mastitis(GLM) is a rare and chronic benign inflammatory disease of the breast. Difficulties exist in the management of GLM for many front-line surgeons and medical specialists who care for patients with inflammatory disorders of the breast. This consensus is summarized to establish evidence-based recommendations for the management of GLM. Literature was reviewed using PubMed from January 1, 1971 to July 31, 2020. Sixty-six international experienced multidisciplinary experts from 11 countries or regions were invited to review the *** of evidence were determined using the American College of Physicians grading system, and recommendations were discussed until consensus. Experts discussed and concluded 30 recommendations on historical definitions,etiology and predisposing factors, diagnosis criteria, treatment, clinical stages, relapse and recurrence of GLM. GLM was recommended as a widely accepted definition. In addition, this consensus introduced a new clinical stages and management algorithm for GLM to provide individual treatment strategies. In conclusion, diagnosis of GLM depends on a combination of history, clinical manifestations, imaging examinations, laboratory examinations and *** approach to treatment of GLM should be applied according to the different clinical stage of GLM. This evidencebased consensus would be valuable to assist front-line surgeons and medical specialists in the optimal management of GLM.

关键词： Granulomatous mastitis Granulomatous lobular mastitis Idiopathic granulomatous mastitis Diagnosis Treatment

基于个体化机器学习的原发性免疫性血小板减少症危重出血预测模型:一项全国前瞻性队列研究

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Science Bulletin 2023年第18期68卷 2106-2114,M0004页

作者： Zhuo-Yu An Ye-jun Wu Yu Hou Heng Mei Wei-xia Nong Wen-Qian Li Hu Zhou Ru Feng Jian-Ping Shen jun Peng Hai Zhou Yi liu yong-Ping Song Lin-Hua Yang Mei-Yun Fang Jian-yong Li Yun-Feng cheng Peng liu Ya-jing Xu Zhao Wang Yi Luo Zhen Cai Hui liu jing-Wen Wang Juan Li xi zhang Zi-Min Sun xiao-Yu Zhu xin Wang Rong Fu Liang Huang Shao-Yuan Wang Tong-Hua Yang Li-Ping Su Liang-Ming Ma xie-Qun chen Dai-Hong liu Hong-xia Yao Jia Feng Hong-Yu zhang Ming Jiang Ze-Ping Zhou Wen-Sheng Wang Xu-Liang Shen Yangjin Baima Yue-Ying Li Qian-Fei Wang qiu-Sha Huang Hai-xia Fu xiao-Lu Zhu Yun He Qian Jiang Hao Jiang Jin Lu xiang-Yu Zhao Ying-jun Chang Tao Wu Yao-Zhu Pan Lin qiu Da Gao A-Rong Jin Wei Li Su-jun Gao Lei zhang Ming Hou xiao-jun Huang xiao-Hui zhang on behalf of the National Cooperative ITP Working Group Peking University People’s Hospital Peking University Institute of HematologyBeijing 100044China Collaborative Innovation Center of Hematology Peking UniversityBeijing 100044China Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation Beijing 100044China National Clinical Research Center for Hematologic Disease Beijing 100044China Department of Hematology Qilu HospitalCheeloo College of MedicineShandong UniversityJinan 250014China Institute of Hematology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430074China Department of Hematology First Affiliated HospitalSchool of MedicineShihezi UniversityShihezi 832002China Department of Hematology Qinghai Provincial People’s HospitalXining 810007China Henan Cancer Hospital Affiliated Cancer Hospital of Zhengzhou UniversityHenan Institute of HematologyZhengzhou 450008China Department of Hematology Beijing HospitalBeijing 100044China Department of Hematology Zhejiang Provincial Hospital of Traditional Chinese MedicineHangzhou 310006China Department of Hematology Senior Department of Hematologythe Fifth Medical Center of PLA General HospitalBeijing 100044China Department of Hematology the Second Hospital of Shanxi Medical UniversityTaiyuan 030001China Department of Hematology Affiliated Zhongshan Hospital of Dalian UniversityDalian 116001China Department of Hematology The First Affiliated Hospital with Nanjing Medical University(Jiangsu Province Hospital)Nanjing 210029China Department of Hematology Zhongshan HospitalFudan UniversityShanghai 200032China Department of Hematology Xiangya HospitalCentral South UniversityChangsha 410008China Department of Hematology Beijing Friendship HospitalCapital Medical UniversityBeijing 100044China Institute of Hematology the First Affiliated HospitalZhejiang UniversityHangzhou 310058China Department of Hematology Beijing Tongren HospitalBeijing 100005China Department of Hematology The First Affiliated HospitalSun Yat-sen UniversityGuang

原发性免疫性血小板减少症(ITP)中少见但至关重要的危重出血事件,给患者的预后、生活质量和治疗决策带来严重影响。尽管有一些研究探讨了ITP中与危重出血相关的风险因素,但目前尚缺乏大样本数据、大规模多中心研究结果以及针对ITP患者... 详细信息

原发性免疫性血小板减少症(ITP)中少见但至关重要的危重出血事件,给患者的预后、生活质量和治疗决策带来严重影响。尽管有一些研究探讨了ITP中与危重出血相关的风险因素,但目前尚缺乏大样本数据、大规模多中心研究结果以及针对ITP患者致命出血事件的预测模型。本研究首次采用国际血栓与止血学会新提出的ITP致命出血标准,利用大样本数据开发了首个基于机器学习的在线应用,用于预测ITP患者的致命出血.研究中,我们使用中国各地大型多中心数据进行开发,并对全国39家医疗中心进行为期一年的外部测试,得到了较好的训练、验证和测试数据集预测能力该基于新算法的便捷网络工具能够快速识别ITP患者的出血风险,辅助临床决策,有望未来降低不良事件的发生。

关键词： Critical bleeding Severe bleeding Immune thrombocytopenia Machine learning Prediction model

Searching for ^(76)Ge neutrinoless double beta decay with the CDEX-1B experiment

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Chinese Physics C 2024年第10期48卷 11-22页

作者： Bing-Tao zhang jun-Zheng Wang Li-Tao Yang Qian Yue Ke-jun Kang Yuan-jing Li Hai-Peng An C.Greeshma Jian-Ping Chang Yun-Huan chen Jian-Ping cheng Wen-Han Dai Zhi Deng Chang-Hao Fang xin-Ping Geng Hui Gong qiu-Ju Guo Xu-Yuan Guo Li He Sheng-Ming He Jin-Wei Hu Han-xiong Huang Tu-chen Huang Hai-Tao Jia xi Jiang S.Karmakar Hao-Bin Li Jian-Min Li Jin Li Qian-Yun Li Ren-Ming-Jie Li Xue-Qian Li Yu-Lan Li Yi-Fan Liang Bin Liao Fong-Kay Lin Shin-Ted Lin Jia-Xuan liu Shu-Kui liu Yan-Dong liu Yu liu Yuan-Yuan liu Zhong-Zhi liu Hao Ma Yu-Cai Mao Qi-Yuan Nie Jin-Hua Ning Hui Pan Ning-Chun Qi Jie Ren xi-Chao Ruan Ze She Manoj Kumar Singh Tian-xi Sun Chang-Jian Tang Wei-You Tang Yang Tian guang-Fu Wang Li Wang Qing Wang Yu-Feng Wang Yun-xiang Wang Henry-Tsz-King Wong Shi-yong Wu Yu-cheng Wu Hao-Yang xing Rui Xu Yin Xu Tao Xue Yu-Lu Yan Nan Yi Chun-Xu Yu Hai-jun Yu Jian-Feng Yue Ming Zeng Zhi Zeng Feng-Shou zhang Lei zhang Zhen-Hua zhang Zhen-Yu zhang Kang-Kang Zhao Ming-Gang Zhao Ji-Fang Zhou Zu-Ying Zhou jing-jun Zhou Key Laboratory of Particle and Radiation Imaging(Ministry of Education)and Department of Engineering Physics Tsinghua UniversityBeijing 100084 Department of Physics Tsinghua UniversityBeijing 100084 Institute of Physics Academia SinicaTaipei 11529 NUCTECH Company Beijing 100084 YaLong River Hydropower Development Company Chengdu 610051 College of Nuclear Science and Technology Beijing Normal UniversityBeijing 100875 College of Physics Sichuan UniversityChengdu 610065 School of Physics Peking UniversityBeijing 100871 Department of Nuclear Physics China Institute of Atomic EnergyBeijing 102413 Sino-French Institute of Nuclear and Technology Sun Yat-sen UniversityZhuhai 519082 School of Physics Nankai UniversityTianjin 300071 Department of Physics Banaras Hindu UniversityVaranasi 221005 Department of Physics Beijing Normal UniversityBeijing 100875

We operated a p-type point contact high purity germanium(PPCGe)detector(CDEX-1B,1.008 kg)in the China Jinping Underground Laboratory(CJPL)for 500.3 days to search for neutrinoless double beta(0νββ)decay of ^(76)Ge.A total of 504.3 kg⋅day effective exposure data was *** anti-coincidence and the multi/single-site event(MSE/SSE)discrimination methods were used to suppress the background in the energy region of interest(ROI,1989–2089 keV for this work)with a factor of 23.A background level of 0.33 counts/(keV⋅kg⋅yr)was *** lower limit on the half life of^(76)Ge 0νββdecay was constrained as T_(1/2)^(0ν)>1.0×10^(23)yr(90%C.L.),corresponding to the upper limits on the effective Majorana neutrino mass:<3.2–7.5 eV.

关键词： neutrinoless double beta decay CDEX point-contact germanium detector ^(76)Ge