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Chinese Physics B 2024年第8期33卷 137-152页

作者：赵会超马雷诺解西阳 Department of Mathematics and Physics and Hebei Key Laboratory of Physics and Energy TechnologyNorth China Electric Power UniversityBaoding 071003China

This paper aims to investigate the multi-soliton solutions of the coupled Lakshmanan–Porsezian–Daniel equations with variable coefficients under nonzero boundary *** equations are utilized to model the phenomenon of nonlinear waves propagating simultaneously in non-uniform optical *** analyzing the Lax pair and the Riemann–Hilbert problem,we aim to provide a comprehensive understanding of the dynamics and interactions of solitons of this ***,we study the impacts of group velocity dispersion or the fourth-order dispersion on soliton *** appropriate parameter selections,we observe various nonlinear phenomena,including the disappearance of solitons after interaction and their transformation into breather-like solitons,as well as the propagation of breathers with variable periodicity and interactions between solitons with variable periodicities.

关键词： soliton Riemann-Hilbert problem non-zero boundary conditions coupled Lakshmanan-Porsezian-Daniel equation

TL1A Promotes Fibrogenesis in Colonic Fibroblasts via the TGF-β1/Smad3 Signaling Pathway

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Current Medical Science 2024年第3期44卷 519-528页

作者： Jia SONG Dong-lei SUN Chen-yang LI Yu-xin LUO Qian LIU Yue YAO Hong ZHANG ting-ting YANG Mei SONG xin-li BAI xiao-lan ZHANG Department of Gastroenterology The Second Hospital of Hebei Medical UniversityHebei Key Laboratory of GastroenterologyHebei Institute of GastroenterologyHebei Clinical Research Center for Digestive DiseasesShijiazhuang050000China Department of Pediatrics The Second Hospital of Hebei Medical UniversityShijiazhuang050000China

Objective Intestinal fibrosis is a refractory complication of inflammatory bowel disease(IBD).Tumor necrosis factor ligand-related molecule-1A(TL1A)is important for IBD-related intestinal fibrosis in a dextran sodium sulfate(DSS)-induced experimental colitis *** study aimed to explore the effects of TL1A on human colonic *** A trinitrobenzene sulfonic acid(TNBS)-induced experimental colitis model of LCK-CD2-TL1A-GFP transgenic(Tg)or wild-type(WT)mice was established to determine the effect and mechanism of TL1A on intestinal *** human colonic fibroblast CCD-18Co cell line was treated concurrently with TL1A and human peripheral blood mononuclear cell(PBMC)*** proliferation and activation of CCD-18Co cells were detected by BrdU assays,flow cytometry,immunocytochemistry and Western *** metabolism was tested by Western blotting and real-time quantitative polymerase chain reaction(RT-qPCR).Results The level of collagen metabolism in the TNBS+ethyl alcohol(EtOH)/Tg group was greater than that in the TNBS+EtOH/WT *** growth factor-β1(TGF-β1)and p-Smad3 in the TNBS+EtOH/Tg group were upregulated as compared with those in the TNBS+EtOH/WT *** proliferation of CCD-18Co cells was promoted by the addition of human PBMC supernatant supplemented with 20 ng/mL TL1A,and the addition of human PBMC supernatant and TL1A increased CCD-18Co proliferation by 24.4%at 24 ***1A promoted cell activation and increased the levels of COL1A2,COL3A1,and TIMP-1 in CCD-18Co *** of CCD-18Co cells with TL1A increased the expression of TGF-β1 and *** TL1A promotes TGF-β1-mediated intestinal fibroblast activation,proliferation,and collagen deposition and is likely related to an increase in the TGF-β1/Smad3 signaling pathway.

关键词： tumor necrosis factor ligand-related molecule-1A fibrosis inflammatory bowel disease myofibroblasts transforming growth factor-β1

Single-crystalline hole-transporting layers for efficient and stable organic light-emitting devices

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Light(Science & Applications) 2024年第7期13卷 1341-1353页

作者： Gao-Da Ye Ran Ding Su-Heng Li lei Ni Shu-ting Dai Nian-Ke Chen Yue-Feng Liu Runda Guo lei Wang xian-Bin Li Bin Xu Jing Feng State Key Laboratory of Integrated Optoelectronics College of Electronic Science and EngineeringJilin University2699 Qianjin Street130012 ChangchunChina. State Key Laboratory of Supermolecular Structures and Materials The Institute of Theoretical ChemistryJilin University2699 Qianjin Street130012 ChangchunChina. Wuhan National Laboratory for Optoelectronics Huazhong University of Science and Technology430074 WuhanChina

Efficient charge-carrier injection and transport in organic light-emitting devices(OLEDs)are essential to simultaneously achieving their high efficiency and long-term ***,the charge-transporting layers(CTLs)deposited by various vapor or solution processes are usually in amorphous forms,and their low charge-carrier mobilities,defectinduced high trap densities and inhomogeneous thickness with rough surface morphologies have been obstacles towards high-performance ***,organic single-crystalline(SC)films were employed as the hole-transporting layers(HTLs)instead of the conventional amorphous films to fabricate highly efficient and stable *** highmobility and ultrasmooth morphology of the SC-HTLs facilitate superior interfacial characteristics of both HTL/electrode and HTL/emissive layer interfaces,resulting in a high Haacke’s figure of merit(FoM)of the ultrathin top electrode and low series-resistance joule-heat loss ratio of the ***,the thick and compact SC-HTL can function as a barrier layer against moisture and oxygen *** a result,the SC-OLEDs show much improved efficiency and stability compared to the OLEDs based on amorphous or polycrystalline HTLs,suggesting a new strategy to developing advanced OLEDs with high efficiency and high stability.

关键词： crystalline amorphous charge

Genome-wide identification of the pectate lyase(PEL)gene family members in Malvaceae,and their contribution to cotton fiber quality

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Journal of Integrative Agriculture 2024年第10期23卷 3264-3282页

作者： Qian Deng Zeyu Dong Zequan Chen Zhuolin Shi ting Zhao Xueying Guan Yan Hu lei Fang Zhejiang Provincial Key Laboratory of Crop Genetic Resources the Advanced Seed InstituteCollege of Agriculture andBiotechnologyZhejiang UniversityHangzhou 300058China Hainan Institute Zhejiang UniversitySanya 572025China

Pectin is a major constituent of the plant cell *** lyase(PEL,EC 4.***.2.2)uses anti-β-elimination chemistry to cleave theα-1,4 glycosidic linkage in the homogalacturonan region of ***,limited information is available on the comprehensive and evolutionary analysis of PELs in the *** this study,we identified 597PEL genes from 10 Malvaceae *** and motif analyses revealed that these PELs are classified into six subfamilies:Clades I,II,III,IV,Va,and *** two largest subfamilies,Clades I and II,contained 237 and222 PEL members,*** members of Clades Va and Vb only contained four or five motifs,far fewer than the other *** duplication analysis showed that segmental duplication played a crucial role in the expansion of the PEL gene family in Gossypium *** PELs from Clades I,IV,Va,and Vb were expressed during the fiber elongation stage,but nearly all PEL genes from Clades II and III showed no expression in any of the investigated fiber developmental *** further performed single-gene haplotype association analysis in 2,*** accessions and 229 *** ***,14 PELs were significantly associated with fiber length and strength traits in *** with superior fiber quality,while only eight GhPEL genes were found to be significantly associated with fiber quality traits in *** findings provide important information for further evolutionary and functional research on the PEL gene family members and their potential use for fiber quality improvement in cotton.

关键词： Malvaceae pectate lyase(PEL) Gossypium species fiber quality

Ultra-high-rate Bi anode encapsulated in 3D lignin-derived carbon framework for sodium-ion hybrid capacitors

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Rare Metals 2024年第3期43卷 1037-1047页

作者： Ze-Hua Lin Xue-Qing Qiu xi-Hong Zu xiao-Shan Zhang lei Zhong Shi-Rong Sun Shu-Hua Hao Ying-Juan Sun Wen-Li Zhang School of Chemical Engineering and Light Industry Guangdong University of Technology(GDUT)Guangzhou510006China Jieyang Branch of Chemistry and Chemical Engineering Guangdong Laboratory(Rongjiang Laboratory) Jieyang515200China School of Advanced Manufacturing Institute of Green Chemistry and Advanced MaterialsGuangdong University of TechnologyJieyang515200China

Bismuth(Bi),as an alloy-based anode material,has attracted much atte ntion in the developme nt of sodiumion hybrid capacitors(SIHCs)due to its high theoretical ***,the volume expansion of the Bi-based anode during the sodiation/desodiation process results in limited rate *** the present work,a porous Bi-based composite was constructed by a one-step hydrothermal method,and Bi was encapsulated in ligninderived nitrogen-doped porous carbon(Bi@LNPC)after *** obtained Bi nanoparticles could effectively adapt to the strain and shorten the diffusion distance of Na^(+).In addition,porous carbon skeleton provides a rigid conductive network for electronic ***,the assembled sodium-ion half-cell with Bi@LNPC anode shows ultra-high-rate *** the current density was enhanced from 0.1 to 50 A·g^(-1),the specific capacity decreased slightly from 351.5 to 342.8 mAh·g^(-1).Even at an extremely high current density of 200 A·g^(-1),it retains 81.3%capacity retention when compared to a current density of 1 A·g^(-1).The SIHCs assembled by Bi@LNPC show a high energy density of 63 Wh·kg^(-1).This work provides an effective method for developing high-rate Bi anode materials for sodium-ion hybrid capacitors(SIHCs)and sodium-ion batteries(SIBs).

关键词： Bismuth Lignin Sodium-ion batteries Sodium-ion hybrid capacitors Rate Porous carbon

Influenza and pneumococcal vaccination coverage and associated factors in patients hospitalized with acute exacerbations of COPD in China:Findings from real-world data

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Chinese Medical Journal 2024年第10期137卷 1179-1189页

作者： Ruoxi He xiaoxia Ren Ke Huang Jieping lei Hongtao Niu Wei Li Fen Dong Baicun Li Ye Wang ting Yang Chen Wang School of Population Medicine and Public Health Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China Department of Respiratory Medicine National Key Clinical SpecialtyBranch of National Clinical Research Center for Respiratory DiseaseXiangya HospitalCentral South UniversityChangshaHunan 410008China Department of Pulmonary and Critical Care Medicine Center of Respiratory MedicineChina-Japan Friendship HospitalBeijing 100029China Institute of Respiratory Medicine Chinese Academy of Medical SciencesBeijing 100029China National Center for Respiratory Medicine Beijing 100029China National Clinical Research Center for Respiratory Diseases Beijing 100029China Department of Clinical Research and Data Management Center of Respiratory MedicineChina-Japan Friendship HospitalBeijing 100029China

Background:Influenza and pneumococcal vaccination are a priority in patients with chronic obstructive pulmonary disease(COPD).However,limited information is available on vaccination coverage among patients with acute exacerbations of COPD(AECOPD)in *** study aimed to determine the rates and associated factors of influenza and pneumococcal vaccination in patients hospitalized with ***:Baseline data from a national,multicenter,hospital-based study that included adult inpatients with AECOPD between 2017 and 2021 were *** outcomes of interest were the influenza vaccination in the past year and the pneumococcal vaccination in the past 5 *** ensure national representativeness,rates were weighted according to the distribution of hospital levels and types enrolled in this *** Poisson regression based on mixed-effects models were used to determine the associated *** independent variables included the region and hospital features where the participants were located,sociodemographic characteristics(age,sex,rural/urban residence,education,etc.),and clinical indicators(COPD disease history,lung function parameters,comorbidities,etc.).The treatment profiles of the vaccinated and unvaccinated participants were ***:Of 6949 eligible participants,the weighted rates of influenza/pneumococcal,influenza,and pneumococcal vaccination were 2.72%(95%confidence interval[CI]:2.34%-3.10%),2.09%(95%CI:1.76%-2.43%),and 1.25%(95%CI:0.99%-1.51%),*** multivariable models,age≥60 years(60-69 years,odds ratio[OR]:1.90,95%CI:1.11-3.25;≥80 years,OR:2.00,95%CI:1.06-3.78),geographical regions(Northern China relative to Eastern China,OR:5.09,95%CI:1.96-13.21),urban residence(OR:1.69,95%CI:1.07-2.66),a higher education level(junior high school,OR:1.77,95%CI:1.21-2.58;senior high school or above,OR:2.61,95%CI:1.69-4.03),former smoking(OR:1.79,95%CI:1.15-2.79),and regular inhaled medication treatment(OR:3.28,95%CI:2.29-4.70)were

关键词： Chronic obstructive pulmonary disease Influenza Pneumococcal Vaccine AECOPD

Clinical and molecular characterization of 10 Chinese children with congenital adrenal hyperplasia due to 11beta‑hydroxylase deficiency

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World Journal of Pediatrics 2024年第4期20卷 422-433页

作者： Wen‑Li Lu xiao‑Yu Ma Jiao Zhang Jun‑Qi Wang ting‑ting Zhang lei Ye Yuan xiao Zhi‑Ya Dong Wei Wang Shou‑Yue Sun Chuan‑Yin Li Rong‑Gui Hu Guang Ning Li‑Dan Zhang Department of Pediatrics Ruijin HospitalShanghai Jiao Tong University School of MedicineNo.197Ruijin 2nd RdHuangpu DistrictShanghai 200025China Department of Pediatric Genetic and Metabolic Endocrinology West China Second University HospitalSichuan UniversityNo.20Section 3Renmin South RoadSichuan 610041China Department of Endocrine and Metabolic Diseases Shanghai Clinical Center for Endocrine and Metabolic DiseasesRuijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China Cancer Center School of MedicineShanghai Tenth People’s HospitalTongji UniversityYanchang Zhong Lu 301St RdJing’an DistrictShanghai 200031China

Background The clinical manifestations of nonclassical 11beta-hydroxylase deficiency are very similar to those of nonclassical 21-hydroxylase *** this study,we investigated the relationship between the clinical and molecular features of congenital adrenal hyperplasia caused by 11beta-hydroxylase deficiency and reviewed the related literature,which are expected to provide assistance for the clinical diagnosis and analysis of congenital adrenal *** Clinical data for 10 Chinese patients diagnosed with congenital adrenal hyperplasia in our hospital from 2018 to 2022 were retrospectively *** examined the effects of gene mutations on protease activity and constructed threedimensional structure prediction models of *** We describe 10 patients with 11beta-hydroxylase gene mutations(n=5,46,XY;n=5,46,XX),with 10 novel mutations were *** patients received treatment at an early stage,with an average age of 2.08±1.66 years,whereas male patients received treatment significantly later,at an average age of 9.77±3.62 *** most common CYP11B1 pathogenic variant in the Chinese population was found to be c.1360C>*** mutations lead to spatial conformational changes that affect protein *** Our study found that there was no significant correlation between each specific mutation and the severity of clinical *** patients with the same gene pathogenic variant may have mild or severe clinical *** correlation between genotype and phenotype needs further ***-dimensional protein simulations may provide additional support for the physiopathological mechanism of genetic mutations.

关键词： 11β-hydroxylase deficiency CYP11B1 Enzymatic activity Phenotype-genotype correlation Threedimensional protein simulations

Metarelation2vec:A Metapath-Free Scalable Representation Learning Model for Heterogeneous Networks

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Tsinghua Science and Technology 2024年第2期29卷 553-575页

作者： lei Chen Yuan Li Yong lei xingye Deng School of Information and Electrical Engineering Hunan University of Science and TechnologyXiangtan 411201China School of Computer Science and Engineering Hunan University of Science and TechnologyXiangtan 411201China

Metapaths with specific complex semantics are critical to learning diverse semantic and structural information of heterogeneous networks(HNs)for most of the existing representation learning ***,any metapaths consisting of multiple,simple metarelations must be driven by domain *** sensitive,expensive,and limited metapaths severely reduce the flexibility and scalability of the existing models.A metapath-free,scalable representation learning model,called Metarelation2vec,is proposed for HNs with biased joint learning of all metarelations in a bid to address this ***,a metarelation-aware,biased walk strategy is first designed to obtain better training samples by using autogenerating cooperation probabilities for all metarelations rather than using expert-given ***,grouped nodes by the type,a common and shallow skip-gram model is used to separately learn structural proximity for each node ***,grouped links by the type,a novel and shallow model is used to separately learn the semantic proximity for each link ***,supervised by the cooperation probabilities of all meta-words,the biased training samples are thrown into the shallow models to jointly learn the structural and semantic information in the HNs,ensuring the accuracy and scalability of the *** experimental results on three tasks and four open datasets demonstrate the advantages of our proposed model.

关键词： metarelation random walk heterogeneous network metapath representation learning

Surface plasmon decorated InGaO deep-UV photodetector array for image sensing and water quality monitoring via highly effective hot electron excitation and interfacial injection

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Science China(Technological Sciences) 2024年第8期67卷 2449-2460页

作者： SHU LinCong SHA ShuLin xi ZhaoYing LI lei YAO SuHao ZHANG JiaHan JI XueQiang ZHANG ShaoHui BIAN Ang JIANG MingMing GUO YuFeng TANG WeiHua LIU Zeng Innovation Center of Gallium Oxide Semiconductor(IC-GAO) College of Integrated Circuit Science and EngineeringNanjing University of Posts and TelecommunicationsNanjing 210023China School of Electronic Information Engineering Inner Mongolia UniversityHohhot 010021China College of Science MIIT Key Laboratory of Aerospace Information Materials and PhysicsNanjing University of Aeronautics and AstronauticsNanjing 211106China Collaborative Innovation Center of Advanced Microstructures School of Electronic Science and EngineeringNanjing UniversityNanjing 210093China Institute of Biological and Medical Engineering Guangdong Academy of SciencesGuangzhou 510316China School of Science Jiangsu University of Science and TechnologyZhenjiang 212100China School of Integrated Circuits Beijing University of Posts and TelecommunicationsBeijing 100876China

In addition to the plasmon-mediated resonant coupling mechanism,the excitation of hot electron induced by plasmon presents a promising path for developing high-performance optoelectronic devices tailored for various *** study introduces a sophisticated design for a solar-blind ultraviolet(UV)detector array using linear In-doped Ga_(2)O_(3) (InGaO)modulated by platinum(Pt)nanoparticles(PtNPs).The construction of this array involves depositing a thin film of Ga_(2)O_(3) through the plasmonenhanced chemical vapor deposition(PECVD)***,PtNPs were synthesized via radio-frequency magnetron sputtering and annealing *** performance of these highly uniform arrays is significantly enhanced owing to the generation of high-energy hot *** process is facilitated by non-radiative decay processes induced by ***,the array achieves maximum responsivity(R)of 353 mA/W,external quantum efficiency(EQE)of 173%,detectivity(D*)of approximately 10~(13)Jones,and photoconductive gain of *** addition,the standard deviation for photocurrent stays below17%for more than 80%of the array units within the ***,the application of this array extends to photon detection in the deep-UV(DUV)*** includes critical areas such as imaging sensing and water quality *** leveraging surface plasmon coupling,the array achieves high-performance DUV photon *** approach enables a broad spectrum of practical applications,underscoring the significant potential of this technology for the advancement of DUV detectors.

关键词： InGaO PECVD surface plasmon solar-blind UV photodetector array optoelectronic applications

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Assessing recent recurrence after hepatectomy for hepatitis Brelated hepatocellular carcinoma by a predictive model based on sarcopenia

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World Journal of Gastroenterology 2024年第12期30卷 1727-1738页

作者： Hong Peng Si-Yi lei Wei Fan Yu Dai Yi Zhang Gen Chen ting-ting xiong Tian-Zhao Liu Yue Huang xiao-Feng Wang Jin-Hui Xu xin-Hua Luo Department of Infectious Diseases Guizhou Provincial People’s HospitalGuiyang 550002Guizhou ProvinceChina Department of Hepatobiliary Surgery Guizhou Provincial People’s HospitalGuiyang 550002Guizhou ProvinceChina

BACKGROUND Sarcopenia may be associated with hepatocellular carcinoma(HCC)following *** traditional single clinical variables are still insufficient to predict *** still lack effective prediction models for recent recurrence(time to recurrenceting characteristic *** Multivariate analysis showed that sarcopenia[Hazard ratio(HR)=1.767,95%CI:1.166-2.678,Pximum diameter of tumor>5 cm(HR=2.222,95%CI:1.285-3.842,Ptinguish the high-risk group of postoperative recurrence of *** Sarcopenia is associated with recent recurrence after hepatectomy for hepatitis B-rel

关键词： Alpha-fetoprotein Hepatitis B virus Hepatectomy Hepatocellular carcinoma Nomogram Predictive models Recurrence Recurrence-free survival Risk factors Sarcopenia