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分振幅法偏振光斯托克斯参量测量系统

光电工程 2008年第5期35卷 93-97页

作者：程敏熙何振江黄佐华华南师范大学物理与电信工程学院广州510006

斯托克斯参量可全面描述光束的偏振态。设计了一个分振幅光度式斯托克斯参量测量系统,在分束镜之间加入1/4波片,使光路在同一平面上。用4个性能一致的探测器同时测量4束与斯托克斯参量有关的光束光强,用偏振片和1/4波片组合产生已知的... 详细信息

斯托克斯参量可全面描述光束的偏振态。设计了一个分振幅光度式斯托克斯参量测量系统,在分束镜之间加入1/4波片,使光路在同一平面上。用4个性能一致的探测器同时测量4束与斯托克斯参量有关的光束光强,用偏振片和1/4波片组合产生已知的偏振态来定标该系统,通过矩阵计算,实现快速测量光束的斯托克斯参量,从而确定光束的偏振态。实验结果表明,测量装置构建容易,调节方便。斯托克斯参量的四个分量测量实验值与理论值的偏差小于6%。

关键词：斯托克斯参量分振幅系统定标偏振计

用于多类别分类的一种加权超球支持向量机算法

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微电子学与计算机 2015年第1期32卷 19-23,28页

作者：刘爽陈鹏李锡祚大连民族学院计算机科学与工程学院辽宁大连116600 大连东软信息学院计算机科学与技术系辽宁大连116023

在One-Class基础上发展起来的超球支持向量机算法能有效地解决多类别分类问题.但是原始的超球支持向量机算法仍有很多需要改进的地方.经过推导和实验,得到如下结论,即超球支持向量机算法过度依赖于每个训练样本,即使该训练样本为噪音数... 详细信息

在One-Class基础上发展起来的超球支持向量机算法能有效地解决多类别分类问题.但是原始的超球支持向量机算法仍有很多需要改进的地方.经过推导和实验,得到如下结论,即超球支持向量机算法过度依赖于每个训练样本,即使该训练样本为噪音数据或是离群异常数据.因此提出在训练之前加入预处理算法,通过相似度计算删除噪音点和异常点.在训练过程中,根据公式计算每个样本的权值,区别对待每个训练样本,确保SMO求解过程迅速收敛.在测试阶段,根据测试点的位置合理选择分类规则进行正确分类.实验结果表明提出的算法可以有效减少噪音数据和异常数据对分类结果的影响,同时提高了分类精度.

关键词：超球支持向量机加权异常点噪音多类别分类

Investigation of Aegilops umbellulata for stripe rust resistance,heading date,and the contents of iron,zinc,and gluten protein

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Journal of Integrative Agriculture 2023年第4期22卷 1258-1265页

作者： SONG Zhong-ping zuo Yuan-yuan xiANG Qin LI Wen-jia LI Jian LIU Gang DAI Shou-fen YAN Ze-hong State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China Chengdu 611130P.R.China Triticeae Research Institute Sichuan Agricultural UniversityChengdu 611130P.R.China

Aegilops umbellulata(UU)is a wheat wild relative that has potential use in the genetic improvement of *** this study,46 *** accessions were investigated for stripe rust resistance,heading date(HD),and the contents of iron(Fe),zinc(Zn),and seed gluten ***-two of the accessions were classified as resistant to stripe rust,while the other four accessions were classified as susceptible to stripe rust in four *** average HD of *** was significantly longer than that of three common wheat cultivars(180.9 d vs.137.0 d),with the exception of PI226500(138.9 d).The *** accessions also showed high variability in Fe(69.74-348.09 mg kg^(-1))and Zn(49.83-101.65 mg kg^(-1))*** accessions(viz.,PI542362,PI542363,and PI554399)showed relatively higher Fe(230.96-348.09 mg kg^(-1))and Zn(92.46-101.65 mg kg^(-1))contents than the *** Fe content of *** was similar to those of *** and *** but higher than those of *** and common *** umbellulata showed a higher Zn content than ***,***,and common wheat,but a lower content than ***,*** had the highest proportion of γ-gliadin among all the species investigated(*** *** species=mean 72.11%vs.49.37%;range:55.33-86.99%vs.29.60-67.91%).These results demonstrated that *** exhibits great diversity in the investigated traits,so it can provide a potential gene pool for the genetic improvement of these traits in wheat.

关键词： Aegilops umbellulata stripe rust resistance heading date Fe and Zn gluten proteins genetic variation

高质量金刚石自支撑膜织构与断裂强度的关系研究

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金属热处理 2005年第6期30卷 2-5页

作者：杨胶溪吕反修毛卫民左铁钏北京工业大学激光工程研究院北京100022 北京科技大学材料科学与工程学院北京100083

利用直流电弧等离子体喷射化学气相沉积在Mo基体上制备了不同织构的金刚石厚膜。用扫描电境(SEM)观察金刚石膜的形貌,用XRD表征晶体取向,用极图和取向分布函数法计算金刚石膜的不同织构,利用三点弯曲法测量金刚石膜的断裂强度。结果表明... 详细信息

利用直流电弧等离子体喷射化学气相沉积在Mo基体上制备了不同织构的金刚石厚膜。用扫描电境(SEM)观察金刚石膜的形貌,用XRD表征晶体取向,用极图和取向分布函数法计算金刚石膜的不同织构,利用三点弯曲法测量金刚石膜的断裂强度。结果表明,金刚石膜的断裂强度随着衍射峰强度比值I(111)/I(220)的增大而不断降低。{110}织构的金刚石膜具有最高的断裂强度。

关键词：金刚石膜自支撑织构断裂强度

The Evolving Bipartite Network and Semi-Bipartite Network Models with Adjustable Scale and Hybrid Attachment Mechanisms

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Open Journal of Applied Sciences 2023年第10期13卷 1689-1703页

作者： Peng zuo Zhen Jia College of Science Guilin University of Technology Guilin China

The bipartite graph structure exists in the connections of many objects in the real world, and the evolving modeling is a good method to describe and understand the generation and evolution within various real complex networks. Previous bipartite models were proposed to mostly explain the principle of attachments, and ignored the diverse growth speed of nodes of sets in different bipartite networks. In this paper, we propose an evolving bipartite network model with adjustable node scale and hybrid attachment mechanisms, which uses different probability parameters to control the scale of two disjoint sets of nodes and the preference strength of hybrid attachment respectively. The results show that the degree distribution of single set in the proposed model follows a shifted power-law distribution when parameter r and s are not equal to 0, or exponential distribution when r or s is equal to 0. Furthermore, we extend the previous model to a semi-bipartite network model, which embeds more user association information into the internal network, so that the model is capable of carrying and revealing more deep information of each user in the network. The simulation results of two models are in good agreement with the empirical data, which verifies that the models have a good performance on real networks from the perspective of degree distribution. We believe these two models are valuable for an explanation of the origin and growth of bipartite systems that truly exist.

关键词： Bipartite Networks Evolving Model Semi-Bipartite Networks Hybrid Attachment Degree Distribution

Spectra of Linear Polyene Molecule-canthaxanthin

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Chemical Research in Chinese Universities 2011年第4期27卷 661-663页

作者： OUYANG Shun-li LI zuo-wei CHEN Yuan-zheng MEN Zhi-wei WU Nan-nan SUN Cheng-lin State Key Laboratory of Superhard Materials College of Physics Jilin University Changehun 130012 P. R. China State Key Laboratory of Theoretical and Computational Chemistry Institute of Theoretical Chemistry Jilin University Changehun 130021 P. R. China

Raman spectra and ultraviolet-visible（UV-Vis） absorption spectra of linear polyene molecule-canthaxan-thin in n-hexane are measured and *** addition,the optimized structure of canthaxanthin was calculated via density functional theory（DFT） functional *** decreasing the concentration,Raman scattering cross section （RSCS） of fundamental frequency is extremely high,and the UV-Vis absorption bands become *** results of coherent weakly damped electron-Lattice vibration model were analyzed.

关键词： Raman spectroscopy Ultraviolet-visible absorption spectrum Canthaxanthin

Integrative analysis of in vivo recording with single-cell RNA-seq data reveals molecular properties of light-sensitive neurons in mouse V1

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Protein & Cell 2020年第6期11卷 417-432页

作者： Jianwei Liu Mengdi Wang Le Sun Na Clara Pan Changjiang Zhang Junjing Zhang Zhentao zuo Sheng He Qian Wu xiaoqun Wang State Key Laboratory of Brain and Cognitive Science CAS Center for Excellence in Brain Science and Intelligence TechnologyInstitute of Brain-Intelligence Technology(Shanghai)Institute of BiophysicsChinese Academy of SciencesBeijing 100101China State Key Laboratory of Cognitive Neuroscience and Learning Beijing Normal UniversityBeijing 100875China University of Chinese Academy of Sciences Beijing 100049China Institute for Stem Cell and Regeneration Chinese Academy of SciencesBeijing 100101China IDG/McGovem Institute for Brain Research Beijing Normal UniversityBeijing 100875China Advanced Innovation Center for Human Brain Protection Beijing Institute for Brain DisordersCapital Medical UniversityBeijing 100069China

Vision formation is classically based on projections from retinal ganglion cells(RGC)to the lateral geniculate nucleus(LGN)and the primary visual cortex(V1).Neurons in the mouse V1 are tuned to light *** the cellular information of the retina and the LGN has been widely studied,the transcriptome profiles of single light-stimulated neuron in V1 remain *** our study,in vivo calcium imaging and whole-cell electrophysiological patch-clamp recording were utilized to identify 53 individual cells from layer 2/3 of V1 as lightsensitive(LS)or non-light-sensitive(NS)by single-cell light-evoked calcium evaluation and action potential *** contents of each cell after functional tests were aspirated in vivo through a patch-clamp pipette for mRNA ***,the three-dimensional(3-D)morphological characterizations of the neurons were reconstructed in a live mouse after the whole-cell *** sequencing results indicated that V1 neurons with a high expression of genes related to transmission regulation,such as Rtn4r and Rgs7,and genes involved in membrane transport,such as Na+/K+ATPase and NMDA-type glutamatergic receptors,preferentially responded to light ***,an antagonist that blocks Rtn4r signals could inactivate the neuronal responses to light stimulation in live *** conclusion,our findings of the vivo-seq analysis indicate the key role of the strength of synaptic transmission possesses neurons in V1 of light sensory.

关键词： light sensitivity vivo-seq patch-seq calcium imaging in vivo whole cell recording in vivo

A Dual Ligand Targeted Nanoprobe with High MRI Sensitivity for Diagnosis of Breast Cancer

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Chinese Journal of Polymer Science 2014年第3期32卷 321-332页

作者： Fa-ming Gong zuo-quan Zhang xiao-dong Chen Lu Zhang xing-su Yu Qi-hua Yang xin-tao Shuai 梁碧玲程度 PCFM Lab of Ministry of Education School of Chemistry and Chemical EngineeringSun Yat-sen University Department of Radiology Sun Yat-sen Memorial HospitalSun Yat-sen University Department of Radiology The Fifth Affiliated HospitalSun Yat-sen University Center of Biomedical Engineering Zhongshan School of MedicineSun Yat-Sen University

Antibody targeted delivery is an effective strategy to improve the diagnostic imaging outcome of nanoscale imaging agents in the focal areas. Dual targeting micelles encapsulating superparamagnetic iron oxide were prepared from the amphiphilic block copolymer poly（ethylene glycol）-poly（e-caprolactone）（PEG-b-PCL） with different targeting ligands cRGD and scFv-ErbB single chain antibody conjugated to the distal ends of PEG block. The breast cancer animal model was established by subcutaneous injecting the BT474 cells into the BALB/c-nu female nude mice and then employed to assess the potential of the dual ligand targeted magnetic micelles as a novel MRI contrast agent on a 1.5 T clinical MR/scanner. The T2 signal intensity of the tumor in animals receiving the dual ligand targeted magnetic micelles via tail vein decreased more significantly than the single ligand targeted and nontargeted magnetic micelles. These results indicate that the dual ligand targeted magnetic micelles, cRGD/scFv-ErbB-PEG-PCL-SPION, have great potential to act as a new type of effective nanoscale MRI contrast agent for early diagnosis of breast cancer.

关键词： Block copolymer micelle Superparamagnetic iron oxide (SPI0) Breast cancer Magnetic resonance imaging(MRI) Herceptin c(Arg-Gly-Asp-d-Phe-Lys) (cRGDfK).

Confocal Laser Endomicroscopy in the Field of Esophageal Diseases

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Advances in Bioscience and Biotechnology 2023年第6期14卷 279-297页

作者： Peiting Xue xiuli zuo Qilu Hospital of Shandong University Jinan China Department of Gastroenterology Qilu Hospital of Shandong University Jinan China

Confocal laser endomicroscopy (CLE) is a new endoscopic imaging technology that allows real-time, high-resolution observation of tomographic images of mucosal cells and subcellular levels in vivo, detecting microscopic structural changes in mucosal morphology, and its in vivo immediate pathological diagnostic capability can avoid delays in mucosal pathological diagnosis and reduce the pain caused by repeated biopsies. CLE is known as “optical biopsy” and compared with other endoscopic techniques, it has obvious advantages. CLE systems include probe-based confocal laser endomicroscopy (pCLE) and endoscope-based confocal laser endomicroscopy (eCLE). Since 2006, CLE has been widely used for the evaluation of various lesions in the digestive system, including esophageal, gastric, and colonic neoplasia, pancreatic cysts and solid lesions, and inflammatory bowel disease. The advent of CLE has made in vivo microscopic imaging possible, which has changed the endoscopic screening and diagnosis of multiple gastrointestinal (GI) lesions. However, the value of its use in GI diseases is still controversial. In this review, we focus on the application of CLE in the field of esophageal diseases.

关键词： Confocal Laser Endomicroscopy (CLE) Barrett’s Esophagus (BE) High-Grade Dysplasia (HGD) Esophagus Cancer (EC) Gastroesophageal Reflux Disease (GERD)