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Nucleation Mechanism for Bainite

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Journal of materials science & technology 2002年第1期18卷 1-2页

作者： xi zhang, xuejun {2. and t.y.Hsu(Xu Zuyao)School of {3. science and Engineering, shanghai jiao tong university, shanghai 2.0030, china [ Manuscript received October 8, 2.01] shanghai jiao {2. Univ Sch Mat Sci & Engn Shanghai 200030 Peoples R China

Based on the experimental results that solute-depleted zone was observed in Cu-2.Zn-4AI (mass fraction) at 52. K, AG is calculated as a positive according to the thermodynamic criteria for the spinodal decomposition of a ternary systems. So, the solute-depleted zone cannot be formed by spinodal decomposition. Dislocation density required by the formation of solute-depleted zone is estimated greater than 7.89×109 cm-2. according to the segregation of solute atoms around dislocations, which is not consistent with the practical situation for the alloy at 52. K. Associated with the internal friction experimental fact that internal friction peaks appear within the incubation for bainitic transformation in Cu-Zn-AI alloy, the equilibrium temperature, tO, is evaluated as 43. K for solute-depleted Cu-2.Zn-3.4AI, which is lower than the experimental temperature 52. K. thus, nucleation by shear mechanism is impossible in this circumstance. therefore, it is concluded that, like bainite in steels and Ag-Cd, bainite in Cu-Zn-AI alloys nucleates by diffusional mechanism, just implied by the experimental existence of solute-depleted zone.

关键词： Bainitic transformation Prebainitic phenomenon Solute-depleted zone Diffusion Nucleation

to improve robustness of mechanical properties of semi-solid cast A3.6 alloy using taguchi design method

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china Foundry 2024年第2期21卷 175-184页

作者： yi-wu Xu Hong-yi Zhan Wei tong jin-ping Li Le-peng {2. De-jiang Li {3.ao-qin Zeng School of materials science and Engineering Shanghai Jiao Tong UniversityShanghai 200240China china science Lab General Motors Global Research&DevelopmentShanghai 201206China General Motors(china)Investment Co. Ltd.Shanghai 201206China china International Intellectech Corporation(CIIC) Beijing 100004China

Mechanical properties of semi-solid casting are dependent on multiple processing parameters,and improper processing parameters will not only reduce mean data but also increase *** present study investigated the impact of parameters in slurry preparation and heat treatment on the yield strength and ductility of t6 heat-treated A3.6 Al-Si alloy using rapid slurry forming(RSF)semi-solid *** focus was primarily on the robustness of mechanical properties based on taguchi design *** analyzing signal-to-noise ratio and minimum value calculated from-3.,the optimum slurry preparation parameters and heat treatment parameters were determined to be no quench,enthalpy exchange material(EEM)temperature of 140℃,EEM-to-melt ratio of 6mass%,stirring time of 18 s,solution heat treated at 52.℃ for 2.h,and ageing heat treated at 190℃ for 6 *** a small batch validation,the-3. yield strength and-3. elongation reach 2.6.1 MPa and 5.03. respectively,showing a satisfactory *** hardness and microstructure of heat-treated samples with the best and worst properties were characterized to gain insight into the underlying mechanisms affecting the mean value and variations of mechanical properties.

关键词： semi-solid casting taguchi design method signal-to-noise ratio mechanical property microstructure

Metabolic landscape of head and neck squamous cell carcinoma informs a novel kynurenine/Siglec-15 axis in immune escape

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Cancer Communications 2024年第6期44卷 670-694页

作者： xin-yu zhang Jian-Bo Shi Shu-Fang {2. Rui-Jie Wang Ming-yu Li Zhi-yuan zhang xi yang Hai-Long Ma Department of Oral Maxillofacial-Head and Neck Oncology Shanghai Ninth People’s HospitalCollege of StomatologyShanghai Jiao Tong University School of MedicineShanghaiP.R.China National Clinical Research Center for Oral Diseases ShanghaiP.R.China shanghai Key Laboratory of Stomatology&shanghai Research Institute of Stomatology ShanghaiP.R.China Department of Second Dental Center Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineCollege of StomatologyShanghai Jiao Tong UniversityShanghaiP.R.China

Background:Metabolic reprograming and immune escape are two hallmarksof ***,how metabolic disorders drive immune escape in head andneck squamous cell carcinoma(HNSCC)remains ***,the aim ofthe present study was to investigate the metabolic landscape of HNSCC and itsmechanism of driving immune ***:Analysis of paired tumor tissues and adjacent normal tissues from69 HNSCC patients was performed using liquid/gas chromatography-mass spectrometry and *** tumor-promoting function of kynurenine(Kyn)was explored in vitro and in *** downstream target of Kyn wasinvestigated in CD8^(+)t *** regulation of CD8+t cells was investigatedafter Siglec-15 overexpression in *** engineering nanoparticle was establishedto deliver Siglec-15 small interfering RNA(siS15),and its association withimmunotherapy response were *** association between Siglec-15and CD8^(+)programmed cell death 1(PD-1)^(+)t cells was analyzed in a HNSCCpatient ***:A total of 178 metabolites showed significant dysregulation in HNSCC,including carbohydrates,lipids and lipid-like molecules,and amino *** these,amino acid metabolism was the most significantly altered,especiallyKyn,which promoted tumor proliferation and *** addition,most immune checkpoint molecules were upregulated in Kyn-high patientsbased on ***,tumor-derived Kyn was transferredinto CD8^(+)t cells and induced t cell functional exhaustion,and blockingKyn transporters restored its killing *** to the results,mechanistically,Kyn transcriptionally regulated the expression of Siglec-15 via arylhydrocarbon receptor(AhR),and overexpression of Siglec-15 promoted immuneescape by suppressing t cell infiltration and *** AhR in vivoreduced Kyn-mediated Siglec-15 expression and promoted intratumoral CD8^(+)tcell infiltration and killing ***,a NH_(2.-modified mesoporous silicananoparticle was des

关键词： head and neck squamous cell carcinoma kynurenine Siglec-15 t cell exhaustion untargeted metabolomics

Bolstering the Mechanical Robustness of Supramolecular Polymer Network by Mechanical Bond

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Chinese Journal of Polymer science 2024年第10期42卷 1536-1544,I0012页

作者： yuan-Hao Wang jing-xi Deng Jun Zhao yi Ding Li yang Zhao-Ming {2. Xu-Zhou yan School of Chemistry and Chemical Engineering Shanghai Jiao Tong UniversityShanghai200240China Frontiers science Center for transformative Molecules Shanghai Jiao Tong UniversityShanghai200240China

Supramolecular polymer networks(SPNs)are celebrated for their dynamic nature,yet they often exhibit inadequate mechanical *** far,the quest to bolster the mechanical resilience of SPNs while preserving their dynamic character presents a formidable ***,we introduce[2.rotaxane into SPN to serve as another cross-link,which could effectively enhance the mechanical robustness of the polymer network without losing the dynamic *** with SPN,the dually cross-linked network(DPN)demonstrates superior breaking strength,young’s modulus,puncture force and toughness,underscoring its superior ***,the cyclic tensile tests reveal that the energy dissipation capacity of DPN rivals,and in some cases surpasses,that of SPN,owing to the efficient energy dissipation pathway facilitated by[2.*** addition,benefiting from stable topological structure of[2.rotaxane,DPN exhibits accelerated recovery from deformation,indicating superior elasticity compared to *** strategy elevates the performance of SPNs across multiple metrics,presenting a promising avenue for the development of high-performance dynamic {3..

关键词： Rotaxane cross-links Dually cross-linked network Supramolecular polymer network Host-guest recognition Dynamic materials

Effect of Post Weld Heat treatment on toughness of Base Metal of Nuclear Reactor Pressure Vessel Steel A53.B

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Journal of Iron and Steel Research International 2011年第S1期18卷 412-416页

作者： LI yun-liang 1,zhang Han-qian 1,2.FU Li-ming 1,CHEN Jiang-biao 1,LI jin-fu 1 (1.School of {2. science and Engineering,shanghai jiao tong university,shanghai 2.02.0,china 2.Research Institute,Baoshan Iron and Steel Co Ltd,shanghai 2.1900,china) shanghai jiao {2. Univ Sch Mat Sci & Engn Shanghai 200240 Peoples R China Baoshan Iron & Steel Co Ltd Res Inst Shanghai 201900 Peoples R China

the effect of post weld heat treatment (PWHt) on the toughness of nuclear reactor pressure vessel steel was *** toughness (K JC) and Charpy impact toughness (KVC) were obtained at different temperatures for quenched-tempered (Qt) and PWHt A53.B steel plates,*** results show that PWHt increases the ductile-brittle transition temperature,and decreases the K JC and *** using SEM and Electron probe micro-analyzer (EPMA),it is found that the size of the precipitation phases increased and molybdenum precipitated during PWHt *** relationship between the size of the precipitation phases and the fracture toughness are analyzed and the influence of microstructure is also briefly discussed.

关键词： nuclear power plant pressure vessel fracture toughness precipitation phases

Consensus statement on research and application of Chinese herbal medicine derived extracellular vesicles-like particles(2.2. edition)

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Chinese Herbal Medicines 2024年第1期16卷 3-12页

作者： Qing Zhao tong Wang Hongbin Wang Peng Cao Chengyu Jiang Hongzhi Qiao Lihua Peng xingdong Lin yunyao Jiang Honglei {2. Huantian {3. Shengpeng Wang yang Wang ying Wang xi Chen Junbing Fan Bo Li Geng Li Bifeng Liu Zhiyang Li Suhua Qi Mingzhen {3. Jianjian Zheng Jiuyao Zhou Lei Zheng Kewei Zhao Guangdong Engineering Research Center of Chinese Herbal Vesicles The Third Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhou 510378China Guangzhou Key Laboratory of Chinese Medicine Research on Prevention and treatment of Osteoporosis The Third Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhou 510378China Institute of Life and Health Engineering the First Affiliated HospitalJinan UniversityGuangzhou 510630China School of Pharmaceutical sciences Guangzhou University of Chinese MedicineGuangzhou 510006China College of Pharmacy Nanjing University of Chinese MedicineNanjing 210046China Institute of Basic Medicine Chinese Academy of Medical SciencesBeijing 100005China College of Pharmaceutical sciences Zhejiang UniversityHangzhou 310030China School of Pharmaceutical sciences Tsinghua UniversityBeijing 100084China Department of Bone and Joint Surgery The First Affiliated Hospital of Jinan UniversityGuangzhou 510630China State Key Laboratory of Quality Research in Chinese Medicine Institute of Chinese Medical SciencesUniversity of MacaoAomen 999078China shanghai jiao {2. {3. Affiliated Sixth People’s Hospital Shanghai 200233China School of Basic Medical sciences Southern Medical UniversityGuangzhou 510515China School of Life sciences Nanjing UniversityNanjing 210008China Nanfang Hospital Southern Medical UniversityGuangzhou 510515China Laboratory Animal Center Guangzhou University of Chinese MedicineGuangzhou 510405China College of Life science and technology Huazhong University of Science and TechnologyWuhan 430074China Nanjing university Medical School Affiliated Nanjing Drum tower Hospital Nanjing 210008China School of Medical and technology Xuzhou Medical UniversityXuzhou 221004China School of Basic Medical sciences Xi’an Jiaotong UniversityXi’an 710065China the First Affiliated Hospital of Wenzhou Medical university WenZhou 325035China

to promote the development of extracellular vesicles of herbal medicine especially the establishment of standardization,led by the National Expert Committee on Research and Application of Chinese Herbal Vesicles,research experts in the field of herbal medicine and extracellular vesicles were invited nationwide with the support of the Expert Committee on Research and Application of Chinese Herbal Vesicles,Professional Committee on Extracellular Vesicle Research and Application,Chinese Society of Research Hospitals and the Guangdong Engineering Research Center of Chinese Herbal *** on the collation of relevant literature,we have adopted the Delphi method,the consensus meeting method combined with the nominal group method to form a discussion draft of“Consensus statement on research and application of Chinese herbal medicine derived extracellular vesicles-like particles(2.2.)”.the first draft was discussed in online and offline meetings on October 12.14,November 2.2.2. and April and May 2.2. on the current status of research,nomenclature,isolation methods,quality standards and research applications of extracellular vesicles of Chinese herbal medicines,and 13.consensus opinions were finally *** the third Academic Conference on Research and Application of Chinese Herbal Vesicles,held on May 2.,2.2.,Kewei Zhao,convenor of the consensus,presented and read the consensus to the experts of the Expert Committee on Research and Application of Chinese Herbal *** consensus highlights the characteristics and advantages of Chinese medicine,inherits the essence,and keeps the righteousness and innovation,aiming to provide a reference for colleagues engaged in research and application of Chinese herbal vesicles at home and abroad,decode the mystery behind Chinese herbal vesicles together,establish a safe,effective and controllable accurate Chinese herbal vesicle prevention and treatment system,and build a bridge for Chinese medicine to the world.

关键词： Chinese herbal medicine extracellular vesicles research application consensus

Nanostructured MXene-based materials for boosting hydrogen sorption properties of Mg/MgH_(2.

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materials Reports(Energy) 2024年第1期4卷 58-68页

作者： yingyan Zhao Bolun Wang Li Ren yinghui Li xi Lin Qiuyu zhang Zhigang Hu Jianxin Zou National Engineering Research Center of Light Alloys Net Forming&State Key Laboratory of Metal Matrix Composites Shanghai Jiao Tong UniversityShanghai200240PR China shanghai Engineering Research Center of Mg materials and Applications&School of materials {3. and Engineering Shanghai Jiao Tong UniversityShanghai200240PR China shanghai Key Laboratory of Hydrogen science&Center of Hydrogen science Shanghai Jiao Tong UniversityShanghai200240PR China

Hydrogen holds the advantages of high energy density,great natural abundance and zero emission,making it suitable for large scale and long term energy storage,while its safe and efficient storage is still *** various solid state hydrogen storage materials,MgH_(2. is promising for industrial applications due to its high gravimetric and volumetric hydrogen densities and the abundance of Mg on ***,the practical application of MgH_(2. has been limited by its stable thermodynamics and slow hydrogen desorption *** is considered as a promising approach for improving the hydrogen storage performance of MgH_(2. and bringing it closer to the requirements of commercial *** is worth mentioning that the recently emerging two-dimensional material,MXene,has showcased exceptional catalytic abilities in modifying the hydrogen storage properties of MgH_(2..Besides,MXene possesses a high surface area,excellent chemical/physical stability,and negatively charged terminating groups,making it an ideal support for the"nanoconfinement"of MgH_(2. or highly active ***,we endeavor to provide a comprehensive overview of recent investigations on MXene-based catalysts and MXene supports for improving the hydrogen sorption properties of Mg/MgH_(2..the mechanisms of hydrogen sorption involved in Mg-MXene based composites are highlighted with special emphases on thermodynamics,kinetics,and catalytic *** aim of this work is to provide a comprehensive and objective review of researches on the development of high-performance catalysts/supports to improve hydrogen storage performances of Mg/MgH_(2. and to identify the opportunities and challenges for future applications.

关键词： Magnesium-based hydride MXene Catalytic modification Nano-confinement Hydrogen storage performance

Expert consensus on irrigation and intracanal medication in root canal therapy

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International Journal of Oral science 2024年第1期16卷 26-35页

作者： xiaoying Zou xin Zheng yuhong Liang Chengfei {2. Bing Fan {3.gping Liang Junqi Ling Zhuan Bian Qing yu Benxiang Hou Zhi Chen xi Wei Lihong Qiu Wenxia Chen Wenxi He xin Xu Liuyan Meng Chen {2. Liming Chen Shuli Deng yayan Lei xiaoli xie xiaoyan Wang {3.hua yu {3. Zhao Song Shen Xuedong Zhou Lin yue Department of Cariology and Endodontology Peking University School and Hospital of Stomatology&National Center of Stomatology&National Clinical Research Center for Oral Diseases&National Engineering Laboratory for Digital and Material Technology of Stomatology&Beijing Key Laboratory of Digital Stomatology&Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health&NMPA Key Laboratory for Dental MaterialsBeijingChina Center of Stomatology Peking University HospitalBeijingChina State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases&West china Hospital of Stomatology Sichuan UniversityChengduChina Department of Emergency Peking University School and Hospital of Stomatology&National Center of Stomatology&National Clinical Research Center for Oral Diseases&National Engineering Laboratory for Digital and Material Technology of Stomatology&Beijing Key Laboratory of Digital Stomatology&Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health&NMPA Key Laboratory for Dental MaterialsBeijingChina Restorative Dental sciences EndodonticsFaculty of DentistryThe University of Hong KongPok Fu LamHong Kong SARChina State Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration Key Laboratory of Oral Biomedicine Ministry of EducationHubei Key Laboratory of StomatologySchool&Hospital of StomatologyWuhan UniversityWuhanChina Department of Endodontics Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineCollege of StomatologyShanghai Jiao Tong UniversityNational Clinical Research Center for Oral DiseasesNational Center for StomatologyShanghai Key Laboratory of StomatologyShanghaiChina Department of Operative Dentistry and Endodontics Hospital of StomatologyGuanghua School of StomatologySun Yat-Sen University&Guangdong Provincial Key Laboratory of StomatologyGuangzhouChina State Key Laboratory of Oral&Maxillofacial Reconstruction and R

Chemical cleaning and disinfection are crucial steps for eliminating infection in root canal treatment. However, irrigant selection or irrigation procedures are far from clear. the vapor lock effect in the apical region has yet to be solved, impeding irrigation efficacy and resulting in residual infections and compromised treatment outcomes.

关键词： treatment irrigation Expert

A comparative study on mechanical and vibroacoustic performance of sandwich cylindrical shells with positive,negative,and zero Poisson’s ratio cellular cores

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Journal of Ocean Engineering and science 2024年第4期9卷 379-390页

作者： Qing Li Peichang Li yongjin Guo xi’an Liu State Key Laboratory of Ocean Engineering Shanghai Jiao Tong UniversityShanghai200240China china Ship Development and Design Center Wuhan430064China MOE Key Laboratory of Marine Intelligent Equipment and System Shanghai Jiao Tong UniversityShanghai200240China

Deep-sea submersibles are significant mobile platforms requiring multi-functional capabilities that are strongly determined by the constituent *** cylindrical protective cover can be advanced by designing their sandwiched cellular materials whose physical properties can be readily parameterized and flexibly *** honeycomb materials are capable of possessing tuned positive,negative,or zero Poisson’s ratios(PPR,NPR,and ZPR),which is expected to produce distinct physical performance when utilized as a cellular core of cylindrical shells for the deep-sea submersibles.A novel cylindrical meta-structure sandwiched with the semi-re-entrant ZPR metamaterial has been designed as well as its similarly-shaped sandwich cylindrical shell structures with PPR and NPR *** mechanical and vibroacoustic performance of sandwich cylindrical shells with cellular materials featuring a full characteristic range of Poisson’s ratios are then compared systematically to explore their potential for engineering applications on submerged pressure-resistant *** respective unit cells are designed to feature an equivalent load-bearing *** properties of pressure resistance,buckling,and sound insulation are simulated,respectively,and the orders of each property are then generalized by systematic *** results indicate that the PPR honeycomb core takes advantage of higher structural strength and stability while the ZPR one yields better energy absorption and sound insulation *** NPR one yields moderate properties and has the potential for lower circumferential *** work explores the application of cellular materials with varied Poisson’s ratios and provides guidance for the multi-functional design of sandwich cylindrical meta-structures.

关键词： Sandwich cylindrical shells Poisson’s ratio Pressure-resistant Buckling Vibroacoustic