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Transcatheter Aortic Valve Replacement in Patients With Pure Native Aortic Regurgitation:Results From a Multicenter Registry Study

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Cardiology Discovery 2024年第2期4卷 134-141页

作者： xiaofei Gao Juan Zhang xiangquan Kong Jing Chen xiang Chen Longyan Zhang xinyong Cai Jiancheng Zhui Nailiang Tian Zhen Ge Bin Wang Qing Zhou xi su Lang Hong Yan Wang Hong Jiang Junjie Zhang Shaoliang Chen Department of Cardiology Nanjing First HospitalNanjing Medical UniversityNanjingJiangsu 210000China Department of Cardiology Renmin Hospital of Wuhan UniversityWuhan UniversityWuhanHubei 430000China Department of Cardiology Xiamen Cardiovascular HospitalXiamen UniversityXiamenFujian 361000China Department of Cardiology Wuhan Asian Heart HospitalWuhanHubei 430000China Department of Cardiology Jiangxi Provincial People's HospitalNanchang UniversityJiangxi 330000China

Objective:Patients with untreated severe aortic regurgitation(AR)have a high risk of *** transcatheter aortic valve replacement(TF-TAVR)is a treatment option for AR;however,the safety and efficacy of this technique have not been sufficiently *** study aimed to evaluate the clinical and anatomical variables correlating with device success of TF-TAVR using a self-expanding valve system for pure ***:Patients with pure native severe AR who underwent TF-TAVR using a self-expanding valve system were registered at 5 Chinese *** primary endpoint was device success at 1 month after *** secondary endpoint was the composite of major adverse cardiovascular events(MACE)at 6 months,including all-cause death,ischemic stroke,emergency conversion to cardiac surgery,and permanent pacemaker *** was used to analyze the left ventricular function before the TAVR procedure and during *** logistic regression and Cox regression analyses were performed to find relevant independent risk ***:Between September 2019 and February 2022,79 patients with AR were enrolled in the *** 1 month,device success was achieved in 60(75.9%)*** 6 months,29(36.7%)patients had *** revealed improved left ventricular function after *** regression analysis demonstrated that the Society of Thoracic surgeons risk score(odds ratio 0.760,95%confidence interval(Cl):0.584-0.989;P=0.041)and annulus perimeter(odds ratio 0.888,95%Cl:0.796-0.992;P=0.035)were 2 predictors of device ***,annulus perimeter(surgeons risk score,was associated with a significant reduction in MACE at 6 months(hazard ratio 2.223,95%Cl:1.060-4.659;P=0.028).Conclusions:TF-TAVR using a self-expanding valve system appears to be a safe and feasible treatment for patients with pure native severe AR,particularly those with a less enlarged annulus.

关键词： Aortic valve Aortic regurgitation Transcatheter aortic valve replacement Device success Self-expanding valve

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终末期心力衰竭机械循环支持的治疗进展

中国心血管杂志 2024年第1期29卷 17-26页

作者：陈静吴明祥苏晞武汉亚心总医院重症医学科 430056

心脏的机械循环支持(MCS)是代替或辅助心脏功能、向心外提供血液灌注、改善机体缺氧状态、促进器官功能恢复的人工器械。在过去的20年中,MCS更多地应用于心力衰竭程度更严重、合并症更复杂的患者,同时还包括因急性心肌梗死或心脏骤停而... 详细信息

心脏的机械循环支持(MCS)是代替或辅助心脏功能、向心外提供血液灌注、改善机体缺氧状态、促进器官功能恢复的人工器械。在过去的20年中,MCS更多地应用于心力衰竭程度更严重、合并症更复杂的患者,同时还包括因急性心肌梗死或心脏骤停而紧急复苏的心原性休克患者。近年来,随着终末期心力衰竭患病率的持续上升及此类患者因心功能受限所致生活质量的严重下降,且对这类患者的药物治疗无效,使以心室辅助装置应用为主的MCS日渐成为顽固性心力衰竭患者的一种重要替代治疗手段。

关键词：机械循环支持心室辅助装置心原性休克终末期心力衰竭

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一站式心脏收缩力调节器联合植入式心律转复除颤器治疗慢性心力衰竭2例

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中华心血管病杂志 2024年第5期52卷 542-544页

作者：谭艳云徐承义苏晞黄克强武汉大学附属武汉亚洲心脏病医院心内科武汉430022 武汉亚心总医院心内科武汉430056

心脏收缩力调节器能增强心肌收缩力,改善心功能,对于不适合心脏再同步化治疗的窄QRS波患者疗效确切,联合植入式心律转复除颤器治疗能有效预防心脏性猝死。该文报道2例一站式心脏收缩力调节器联合植入式心律转复除颤器治疗慢性心力衰竭... 详细信息

心脏收缩力调节器能增强心肌收缩力,改善心功能,对于不适合心脏再同步化治疗的窄QRS波患者疗效确切,联合植入式心律转复除颤器治疗能有效预防心脏性猝死。该文报道2例一站式心脏收缩力调节器联合植入式心律转复除颤器治疗慢性心力衰竭的案例。2例患者使用优化药物治疗效果均不佳,经评估后进行一站式手术,术后器械正常工作,短期随访显示两患者心功能均得到改善,为一站式手术的有效性及安全性提供了一定参考。

关键词：心力衰竭心脏收缩力调节器植入式心律转复除颤器左西孟旦器械治疗肌浆/内质网Ca2+ATP酶钠钙交换体绝对不应期电刺激

基于桩土耦合作用的单桩式风机承载力可靠性研究

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船舶力学 2024年第8期28卷 1254-1264页

作者：汤苏西殷齐麟翟金金王薇江苏科技大学江苏镇江212100

大直径单桩是海上风机重要的基础型式,其承载力可靠性是桩基设计的关键问题。本文考虑实际多土层的地质条件以及风速、波高、周期等环境参数的相关性,改进并采用BP神经网络与蒙特卡罗模拟相结合的方法,对大直径单桩风机在正常使用极限状... 详细信息

大直径单桩是海上风机重要的基础型式,其承载力可靠性是桩基设计的关键问题。本文考虑实际多土层的地质条件以及风速、波高、周期等环境参数的相关性,改进并采用BP神经网络与蒙特卡罗模拟相结合的方法,对大直径单桩风机在正常使用极限状态(SLS)下的承载力可靠性开展研究;基于桩-土接触面模型进行确定性的承载力分析,分别对砂土、粘土海床中的准确性进行验证,并采用该模型确定神经网络训练点的准确解;最后,以LW 8MW风机为例,进行SLS下单桩风机承载力可靠性分析。该方法可以为国内后续海上风电场的设计建设提供参考。

关键词：单桩风机承载力可靠性桩-土接触面模型 BP神经网络与蒙特卡罗模拟参数相关性

硝酸铈与脱落酸处理对紫花苜蓿种子萌发和幼苗生理特性的影响

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草业学报 2024年第6期33卷 175-186页

作者：高金柱赵东豪高乐苏喜浩何学青西北农林科技大学草业与草原学院陕西杨凌712100

为研究稀土铈(Ce)与外源脱落酸(ABA)处理对紫花苜蓿种子萌发和幼苗生理特性的影响,采用浓度分别为5、10、20μmol·L^(-1)的硝酸铈、ABA及硝酸铈和ABA(1∶1)的混合溶液处理苜蓿种子进行发芽试验,探究其对种子的萌发、生长,幼苗的叶绿素... 详细信息

为研究稀土铈(Ce)与外源脱落酸(ABA)处理对紫花苜蓿种子萌发和幼苗生理特性的影响,采用浓度分别为5、10、20μmol·L^(-1)的硝酸铈、ABA及硝酸铈和ABA(1∶1)的混合溶液处理苜蓿种子进行发芽试验,探究其对种子的萌发、生长,幼苗的叶绿素含量、抗氧化酶活性和渗透调节物质含量等指标的影响。结果表明:5~10μmol·L^(-1)硝酸铈处理刺激了紫花苜蓿种子的萌发,并增大了根粗(5~20μmol·L^(-1));而ABA(5~20μmol·L^(-1))抑制了种子萌发和幼苗生长,且与硝酸铈混合处理解除了硝酸铈对根粗的膨大作用。硝酸铈可以缓解ABA对叶绿素含量的降低,并降低幼苗叶抗氧化酶活性,而Ce与ABA混合处理可显著提高紫花苜蓿幼苗的抗氧化酶活性。因此,硝酸铈处理对紫花苜蓿萌发及生长有一定的积极作用;硝酸铈与ABA混合处理时,ABA在调节紫花苜蓿种子萌发和幼苗生长过程以及生理特性中发挥主导作用,硝酸铈+ABA处理的幼苗高抗氧化活性,表明幼苗受到胁迫。研究结果为稀土铈和ABA对紫花苜蓿萌发期的影响提供了参考。

关键词：紫花苜蓿硝酸铈脱落酸种子萌发抗氧化性

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磁流变惯容器设计与性能分析

重庆大学学报 2024年第8期47卷 39-46页

作者：于建强尹佳威张赓苏喜吴晅陈世嵬中国电子科技南湖研究院机器人实验室浙江嘉兴314000 重庆科技大学土木与水利工程学院重庆401331 嘉兴南湖学院新材料工程学院浙江嘉兴314001

为了提高传统磁流变阻尼器在低频域的减振性能,提出了一种新型磁流变惯容器,包括变阻尼单元和惯容单元两部分,由磁流变阀、液压马达与飞轮等组成。利用活塞杆与缸筒的相对运动,实现变阻尼单元内的磁流变液在磁流变阀内往复流动,通过调... 详细信息

为了提高传统磁流变阻尼器在低频域的减振性能,提出了一种新型磁流变惯容器,包括变阻尼单元和惯容单元两部分,由磁流变阀、液压马达与飞轮等组成。利用活塞杆与缸筒的相对运动,实现变阻尼单元内的磁流变液在磁流变阀内往复流动,通过调控线圈上电流大小改变输出阻尼的大小;同时,实现油液推动液压马达输出轴及飞轮转动,输出器件的惯容特性。为提高磁流变阀内置通道的磁场利用率,提出了磁路设计优化方法,采用有限元方法对磁流变阀内部磁场强度进行仿真。结合磁场仿真与理论分析,设计并试制了样机,搭建了器件性能平台进行测试。结果表明,所设计器件能够表现出惯容特性,具有良好的阻尼可控性。

关键词：磁流变变阻尼器件惯容磁场

A bi-population immune algorithm for weapon transportation support scheduling problem with pickup and delivery on aircraft carrier deck

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Defence Technology（防务技术） 2023年第4期22卷 119-134页

作者： Fang Guo Wei Han xi-chao su Yu-jie Liu Rong-wei Cui Naval Aviation University No.188Ermalu RoadZhifu DistrictYantai264001Shandong ProvinceChina

The weapon transportation support scheduling problem on aircraft carrier deck is the key to restricting the sortie rate and combat capability of carrier-based *** paper studies the problem and presents a novel solution *** the interference of the carrier-based aircraft deck layout on the weapon transportation route and precedence constraint into consideration,a mixed integer formulation is established to minimize the total objective,which is constituted of makespan,load variance and accumulative transfer time of support *** approach is developed for the ***,based on modeling the carrier aircraft parked on deck as convex obstacles,the path library of weapon transportation is constructed through visibility graph and Warshall-Floyd *** then propose a bi-population immune algorithm in which a population-based forward/backward scheduling technique,local search schemes and a chaotic catastrophe operator are ***,the randomkey solution representation and serial scheduling generation scheme are adopted to conveniently obtain a better *** Taguchi method is additionally employed to determine key parameters of the ***,on a set of generated realistic instances,we demonstrate that the proposed algorithm outperforms all compared algorithms designed for similar optimization problems and can significantly improve the efficiency,and that the established model and the bi-population immune algorithm can effectively respond to the weapon support requirements of carrier-based aircraft under different sortie missions.

关键词： Carrier-based aircraft Weapon transportation support scheduling Pickup and delivery Bi-population immune algorithm

A Pyrazine-Based 2D Conductive Metal-Organic Framework for Efficient Lithium Storage

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中国化学:英文版 2023年第14期41卷 1691-1696页

作者： xiaoxiao sun xiaoli Yan Keming Song Ting Zhang Zongfan Yang xi su Weihua Chen Long Chen Tianjin Key Laboratory of Molecular Optoelectronic Science Department of ChemistryTianjin UniversityTianjin300072 China College of Chemistry and Green Catalysis Center Zhengzhou UniversityZhengzhouHenan450001 China State Key Laboratory of supramolecular Structure and Materials College of ChemistryJilin UniversityChangchunJilin130012 China

The merits of intrinsic electrical conductivity, high specific surface area, tunable chemical composition and tailor-made properties enable two-dimensional conductive metal-organic frameworks (2D c-MOFs) as promising next-generation electrode materials in the field of energy storage and conversion. Herein, we have designed and synthesized a novel pyrazine-based 2D c-MOF (TPQG-Cu-MOF) bearing extended π-conjugated structure and abundant redox active sites. Thanks to the excellent redox reversibility of pyrazine units and CuO2 units, as well as the insolubility of the rigid framework skeleton, TPQG-Cu-MOF as the cathode material of lithium-ion battery exhibits a reversible specific capacity (150.2 mAh·g–1 at 20 mAh·g–1), good cycling stability (capacity retention of 82.6% after 500 cycles at 1 A·g–1) and excellent rate performance. Comprehensive ex-situ spectroscopic studies revealed the reversible redox activity of pyrazine units and CuO2 units of TPQG-Cu-MOF during the Li+ insertion/extraction process. The deepening fundamental understanding of the structure-property relationship was proposed, which might pave the way for further development of efficient MOF-based energy storage devices.

关键词： Two-dimensional Conductive metal-organic frameworks Pyrazine Energy storage Lithium-ion battery Cathode Stability Comprehensivesummary

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急性心肌梗死相关心室电风暴的研究现状

心血管病学进展 2024年第7期45卷 627-631页

作者：周磊徐承义韩宏伟鄢华苏晞武汉亚洲心脏病医院心内科湖北武汉430022

心室电风暴是临床急危重症,多见于缺血性心脏病患者,尤其是心肌梗死急性期,常伴有血流动力学异常,具有较高的复发率和死亡率。现回顾近年的临床研究,对急性心肌梗死相关心室电风暴的研究现状予以综述。

关键词：心律失常电风暴急性心肌梗死药物治疗室性心律失常

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