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Characterization of a Novel 1Ay Gene and Its Expression Protein in Triticum urartu

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Agricultural Sciences in China 2010年第11期9卷 1543-1552页

作者： hu xi-gui Triticeae Research Institute Sichuan Agricultural University Wenjiang 611130 P.R. China Key Laboratory of Crop Genetic Resources and Improvement Ministry of Education/Sichuan Agricultural University Ya 'an 625014 P.R. China Key Laboratory of Adaptation and Evolution of Plateau Biota Northwest Institute of Plateau Biology Chinese Academy of Sciences Xining 810001 P.R. China

High molecular weight glutenin subunit （HMW-GS） plays an important role in determining dough property and breadmaking quality, and the exploration of novel genes for HMW-GS will be crucial for quality improvement program. A gene coding the y type HMW-GS at Glu-A1 locus in Triticum urartu （AA, 2n=2×= 14） with an electrophoretic mobility similar to that of 1Dyl2, was cloned, sequenced, and heterologously expressed. This novel active lay gene FJ404595 was confirmed by structure analyses of nucleotide and deduced amino acid sequences combining with phylogenetic analysis. The open reading frame （ORF） of this gene was 1 830 bp, encoded a protein of 608 amino acid residues containing 46 hexapeptides and 14 nonapeptides, which was mostly similar to the lAy gene AM183223 at a high identity of 99.62% with the two substitutions of both leucine/proline and valine/glutamate, obviously different from the lAy gene EU984504 with 587 residues containing 44 hexapeptides and 13 nonapeptides in T. urartu. The amino acid （leucine） at 446 differed from that （proline） of all the eight compared active lAy subunits. The predicted secondary protein structure implied that this lAy subunit might also have positive impact on flour processing quality.

关键词： Triticum urartu lAy subunit expression electrophoretic mobility secondary structure

Parameter Processes of a Strong Laser in Partially Stripped Plasmas

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Chinese Physics Letters 2000年第12期17卷 893-895页

作者： hu xi-Wei Department of Modern Physics University of Science and Technology of ChinaHefei 230026

The effects of the nonlinear polarization in a partially stripped plasma on the parameter processes of a strong laser are discussed. The nonlinear mode coupling equations of stimulated Raman scattering (SRS) are derived. The linear instability growth rates of SRS and stimulated Brillouin scattering (SBS) are given. When the pump wave intensity I0 > 1017 W/cm2, the third order susceptibility associated with bound electrons will reduce the SRS and SBS linear growth rate enormous1y. In addition, the nonlinear susceptibility can affect the nonlinear evolution of SRS and SBS significantly.

关键词： nonlinear susceptibility Parameter

Mean Index for Non-periodic Orbits in Hamiltonian Systems

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Acta Mathematica Sinica,English Series 2022年第1期38卷 291-310页

作者： xi Jun hu Li WU School of Mathematics Shandong UniversityJi’nan 250100P.R.China

In this paper,we define mean index for non-periodic orbits in Hamiltonian systems and study its *** general,the mean index is an interval in R which is uniformly continuous on the *** show that the index interval is a point for a quasi-periodic *** mean index can be considered as a generalization of rotation number defined by Johnson and Moser in the study of almost periodic Schr¨odinger *** by their works,we study the relation of Fredholm property of the linear operator and the mean index at the end of the paper.

关键词： Mean index Maslov-type index quasi-periodic orbit Fredholm operator

Nonlinear Evolutions of Stimulated Raman and Brillouin Scattering Processes in Partially Stripped-Ion Plasmas

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Chinese Physics Letters 2001年第9期18卷 1230-1233页

作者： hu Ye-Min hu xi-Wei Departmentof Electrical Engineering Huazhong University of Science and TechnologyWuhan 430074 Department of Modern Physics University of Science and Technology of ChinaHefei 230026

Numerical analyses for the nonlinear evolutions of stimulated Raman scattering (SRS) and stimulated Brillouin scattering (SBS) processes are given. Various effects of the second- and third-order nonlinear susceptibilities on the SRS and SBS processes are studied. The nonlinear evolutions of SRS and SBS processes are atfected more efficiently than their linear growth rates by the nonlinear susceptibility.

关键词： Brillouin nonlinear Nonlinear

Investigation on Surface Plasmon Polaritons and Localized Surface Plasmon Production Mechanism in Micro-Nano Structures

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Journal of Electronic Science and Technology 2022年第1期20卷 20-29页

作者： Ling-xi hu Min hu Sheng-Gang Liu Terahertz Research Center School of Electronic Science and EngineeringUniversity of Electronic Science and Technology of ChinaChengdu 610054 Key Laboratory of Terahertz Technology(Ministry of Education) University of Electronic Science and Technology of ChinaChengdu 610054

The simulation mechanism of surface plasmon polaritons(SPPs)and localized surface plasmon(LSP)in different structures was studied,including the Au reflection grating(Au grating),Au substrate with dielectric ribbons grating(Au substrate grating),and pure electric conductor(PEC)substrate with Au ribbons grating(Au ribbons grating).And the characteristics of the Smith-Purcell radiation in these structures were *** results show that SPPs are excited on the bottom surface of Au substrate grating grooves and LSP is stimulated on the upper surface both of Au ribbons grating grooves and Au grating *** to the irreconcilable contradiction between optimizing the grating diffraction radiation efficiency and optimizing the SPPs excitation efficiency in the Au substrate grating,only 40-times enhancement of the radiation intensity was obtained by excited ***,the LSP enhanced structure overcomes the above problem and gains much better radiation enhancement ability,with about 200-times enhancement obtained in the Au ribbons grating and more than 500-times enhancement obtained in the Au *** results presented here provide a way of developing miniature,integratable,tunable,high-power-density radiation sources from visible light to ultraviolet rays at room temperature.

关键词： Coherent radiation high-power radiation localized surface plasmon(LSP) micro-nano structure Smith-Purcell radiation surface plasmon polaritons(SPPs)

Hot deformation behavior and microstructure evolution of as-cast AZ91D magnesium alloy without pre-homogenization treatment

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Rare Metals 2013年第4期32卷 338-346页

作者： Yan Xu Lian-xi hu Yu Sun School of Materials Science and Engineering Harbin Institute of Technology School of Mechanical Engineering Beihua University

The deformation behavior and the microstruc-ture evolution of as-cast AZ91D magnesium alloy without pre-homogenization treatment were systematically inves-tigated. The flow stress behavior was studied by com-pression tests in strain rate range of 0.001-1.000 s^-1 and deformation temperature range of 220-380 ℃ with a maximum deformation strain of 60 %. The dependence of flow stress on deformation temperature and strain rate was described by hyperbolic sine constitutive equation. Through regression analysis, the average apparent activa- tion energy and coefficient of strain rate sensitivity were estimated to be 181.98 ***^-1 and 0.14, respectively. The results also reveal that the variation of peak stress depends on strain rate and deformation temperature. Microstructure observation shows that, at temperatures higher than 300 ℃ and strain rates lower than 0.01 s^-1, DRX developed extensively at the grain boundaries and in the core of coarse grains, resulting in a more homogeneous microstructure. Furthermore, the effects of strain, defor-mation temperature, strain rate, and eutectic β phase on the microstructure evolution of as-cast AZ91D magnesium alloy were discussed.

关键词： AZ91D magnesium alloy Isothermalcompression Constitutive equation Peak stress Microstructure evolution

THE SOLVABILITY CONDITIONS FOR THE INVERSE PROBLEM OF BISYMMETRIC NONNEGATIVE DEFINITE MATRICES

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Journal of Computational Mathematics 2000年第6期18卷 597-608页

作者： Dong-xiu xie Lei Zhang xi-yan hu Department of Applied Mathematics Dalian University of TechnologyDalian 116023China Department of Applied Mathematics Hunan UniversityChangsha 410082China hunan Computing Center Changsha 410012China

A = (a[sub ij]) ∈ R[sup n×n] is termed bisymmetric matrix if a[sub ij] = a[sub ji] = a[sup n ? j + 1, n ? i + 1], i, j = 1, 2 ··· n. We denote the set of all n x n bisymmetric matrices by BSR[sup n x n]. This paper is mainly concerned with solving the following two problems: Problem I. Given X, B ∈ R[sup n×m], find A ∈ P[sub n] such that AX = B, where P[sub n] = {A ∈ BSR[sup n×n]| x[sup T] Ax ≥ 0, ?x ∈ R[sup n]}. Problem II. Given A[sup *] ∈ R[sup n×n], find ? ∈ S[sub E] such that ||A[sup *] - ?||[sub F] = ... ||A[sup *] - A||[sub F] where || · ||[sub F] is Frobenius norm, and S[sub E] denotes the solution set of problem I. The necessary and sufficient conditions for the solvability of problem I have been studied. The general form of S[sub E] has been given. For problem II the expression of the solution has been provided. [ABSTRACT FROM AUTHOR]

关键词： Frobenius norm bisymmetric matrix the optimal solution

Platinum drugs:from Pt(Ⅱ)compounds,Pt(Ⅳ)prodrugs,to Pt nanocrystals/nanoclusters

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Science Bulletin 2017年第8期62卷 589-596页

作者： xi hu Fangyuan Li Nabila Noor Daishun Ling Zhejiang Province Key Laboratory of Anti-Cancer Drug Research College of Pharrnaceutical SciencesZhejiang UniversityHangzhou 310058China Key Laboratory of Biomedical Engineering of the Ministry of Education College of Biomedical Engineering&Instrument ScienceZhejiang UniversityHangzhou 310027China

Platinum(Pt) based drugs, such as cisplatin, are widely used as anti-cancer agents, but their severe adverse reactions and resistance of cancer patients have limited their board clinical use. For the last few decades, Pt(Ⅱ) compounds, Pt(Ⅳ) prodrugs as well as smart drug delivery systems have been developed to overcome these problems. However, most conventional strategies rely on the similar anti-cancer mechanism with cisplatin and consequently only achieve limited success. Recently, Pt nanocrystals/nanoclusters(Pt NCs), with a brand new anti-cancer mechanism, have shown a promising potential in targeted cancer therapy, especially in Pt resistance circumvention. This review is helpful to understand the research strategies of Pt drugs, particularly, the recent developments and medical applications of Pt NCs.

关键词： Platinum Pt(Ⅱ) Pt(Ⅳ) Pt nanocrystals/nanoclusters Pt resistance Cancer therapy

Nanotechnology-based tumor metabolic reprogramming:Insights into nutrient-delivery and metabolism reactivation therapy

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Acta Pharmaceutica Sinica B 2024年第10期14卷 4619-4621页

作者： xi hu Daishun Ling School of Pharmacy Anhui University of Chinese MedicineHefei 230038China Institute of Pharmaceutics Anhui Academy of Chinese MedicineHefei 230038China Anhui Province Key Laboratory of Pharmaceutical Preparation Technology and Application Anhui University of Chinese MedicineHefei 230038China Frontiers Science Center for Transformative Molecules School of Chemistry and Chemical EngineeringNational Center for Translational MedicineShanghai Jiao Tong UniversityShanghai 200240China WLA Laboratories Shanghai 201203China

Metabolic reprogramming in cancer is not only a core hallmark but also exposes treatment *** key processes required for tumor initiation and progression—continuous self-renewal,survival,and proliferation—are known to be under metabolic control^(1).Therapeutic opportunities arise from dysregulated metabolism and metabolic crosstalk,as tumor cells become heavily dependent on specific metabolic pathways such as glucose,amino acid,and fatty acid metabolism,as well as nucleotide synthesis^(2).However,many anti-metabolite drugs,including glycolysis inhibitors,have not been successfully applied in clinical settings due to their low specificity and undesirable side effects.

关键词： Metabolic therapy Metabolic reprogramming Cancer metabolism Metabolism reactivation therapy Melanin metabolism Nutrient-delivery Tumor therapy Nanotechnology