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Service Function Chain Migration in LEO Satellite Networks

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China Communications 2024年第3期21卷 247-259页

作者： geng Yuhui Wang Niwei Chen xi Xu xiaofan Zhou Changsheng Yang Junyi xiao Zhenyu Cao xianbin School of Electronic and Information Engineering Beihang UniversityBeijing 100191China Key Laboratory of Advanced Technology of Near Space Information System Ministry of Industry and Information Technology of ChinaBeijing 100191China Shanghai Key Laboratory of Satellite Network Shanghai 201204China Shanghai Satellite Network Research Institute Co. Ltd.Shanghai 201204China

With the advancements of software defined network(SDN)and network function virtualization(NFV),service function chain(SFC)placement becomes a crucial enabler for flexible resource scheduling in low earth orbit(LEO)satellite networks.While due to the scarcity of bandwidth resources and dynamic topology of LEO satellites,the static SFC placement schemes may cause performance degradation,resource waste and even service failure.In this paper,we consider migration and establish an online migration model,especially considering the dynamic topology.Given the scarcity of bandwidth resources,the model aims to maximize the total number of accepted SFCs while incurring as little bandwidth cost of SFC transmission and migration as possible.Due to its NP-hardness,we propose a heuristic minimized dynamic SFC migration(MDSM)algorithm that only triggers the migration procedure when new SFCs are rejected.Simulation results demonstrate that MDSM achieves a performance close to the upper bound with lower complexity.

关键词： network function virtualization(NFV) resource allocation satellite networks service function chain(SFC) SFC migration SFC placement soft-ware defined network(SDN)

Direct detection of C9orf72 hexanucleotide repeat expansions by nanopore biosensor

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Chinese Chemical Letters 2024年第5期35卷 351-354页

作者： xinqiong Li Guocheng Rao xi Peng Chan Yang Yanjing Zhang Yan Tian xianghui Fu Jia geng State Key Laboratory of Biotherapy and Cancer Center West China HospitalSichuan University and Collaborative Innovation Center of BiotherapyChengdu 610041China Division of Endocrinology and Metabolism West China School of Medicine/West China HospitalSichuan UniversityChengdu 610041China Department of Endocrinology and Metabolism Affiliated Hospital of North Sichuan Medical CollegeNorth Sichuan Medical CollegeNanchong 637000China Division of Endocrinology and Metabolism National Clinical Research Center for GeriatricsState Key Laboratory of Biotherapy and Cancer CenterWest China HospitalSichuan University and Collaborative Innovation Center of BiotherapyChengdu 610041China Department of Laboratory Medicine State Key Laboratory of BiotherapyMed-X Center for ManufacturingWest China HospitalSichuan University and Collaborative Innovation CenterChengdu 610041China Tianfu Jincheng Laboratory City of Future MedicineChengdu 641400China

Diagnostic C9orf72 hexanucleotide repeat expansions(C9-HRE)is essential for the early and accurate diagnosis of amyotrophic lateral sclerosis(ALS)and will provide support for the prognosis and gene therapy of ALS.In the present study,by combining catalytic hairpin assembly(CHA)with Mycobacterium smegmatis porin A(MspA)nanopore,a new nanopore-based strategy for the detection of C9-HRE was reported.Less than 30 repeats of C9-HRE could be detected via this method,and the results have the potential to help distinguish between patients and healthy individuals.Moreover,the method demonstrated its great specificity for C9-HRE by identifying other repeat expansions.Given the high selectivity,this approach had been successfully used to detect C9-HRE in cell and blood samples with high accuracy.This detection strategy is user-friendly and has a strong anti-interference ability,thus providing a powerful tool for clinical diagnosis.

关键词： MspA nanopore C9orf72 HRE Detection Biosensor Catalytic hairpin assembly

Carbon emission reduction:Contribution of photovoltaic power and practice in China

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China Geology 2024年第2期7卷 371-376页

作者： Liang Wang Li-qiong Jia geng xie xi-jie Chen Yang Liu Natural Resources Integrated Survey Command Center China Geological SurveyMinistry of Natural ResourcesBeijing 100055China Development and Research Center China Geological SurveyMinistry of Natural ResourcesBeijing 100037China Center for Geophysical Survey China Geological SurveyLangfang 065000China

As a clean and renewable form of energy,photovoltaic(PV)power generation converts solar energy into electrical energy,reducing the consumption of fossil fuels and significantly lowering greenhouse gas emissions.Amidst the global transition towards cleaner forms of energy,countries all around the world are vigorously developing PV technology.

关键词： convert power emissions

Reversing artemisinin resistance by leveraging thermo-responsive nanoplatform to downregulating GSH

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Chinese Chemical Letters 2024年第6期35卷 392-397页

作者： Yong-Dan Zhao Yidan Wang Rongrong Wang Lina Chen Hengtong Zuo xi Wang Jihong Qiang geng Wang Qingxia Li Canqi Ping Shuqiu Zhang Hao Wang School of Pharmacy Shanxi Medical UniversityTaiyuan 030001China National Center for Nanoscience and Technology Beijing 100190China Artemisinin Research Center Institute of Chinese Materia MedicaBeijing 100700China

Artemisinin(ART)resistance has been an emerging clinical problem,severely compromising antimalarial efficacy and threatening the global malaria elimination campaign.Albeit intensive studies about the molecular mechanism for ART resistance are under way,no effective therapeutic targets for reversing resistance have been applied.Here,we explore glutathione(GSH)as a therapeutic target to develop a thermo-responsive nanoplatform to specifically co-deliver ART and GSH synthesis inhibitor(L-buthionine sulfoximine,BSO)in a sustained manner,effectively reversing ART resistance in vivo.By combining with BSO,ART exerts increased antimalarial activity with reduced half-maximal inhibitory concentration(IC50)by 7.43-fold in ART-resistant strains.This work reveals that the GSH in ART-resistant parasites can be a promising therapeutic target for reversing ART resistance,paving the way for developing drug candidates and intelligent nanomedicines in malaria therapy.

关键词： Nanomedicines Drug delivery Artemisinins resistance Malaria Glutathione

Review on recent advances of inorganic electrode materials for potassium-ion batteries

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Tungsten 2024年第1期6卷 174-195页

作者： Jian-Zhen xiong Ze-Cheng Yang xin-Liang Guo xi-Ying Wang Chao geng Zong-Fu Sun An-Yong xiao Quan-Chao Zhuang Ya-xin Chen Zhi-Cheng Ju School of Materials Science and Physics China University of Mining and TechnologyXuzhou 221116China

Rechargeable potassium-ion batteries(PIBs)have great potential in the application of electrochemical energy storage devices due to the low cost,the abundant resources and the low standard reduction potential of potassium.As electrode materials are the key factors to determine the electrochemical performance of devices,relevant research is being carried out to build high-performance PIBs.In recent years,significant progress has been made in the study of the design of inorganic electrode materials.Herein,we review the cathode materials(Prussian blue and its analogues,layered oxides and poly anionic compounds)and the anode materials(antimony-based,selenium-based and bismuth-based compounds).On the basis of previous work,the structural design principles for improving the performance of electrode materials are reasonably summarized.At the same time,the problems that need to be solved in the preparation of electrode materials and the direction of future research and improvement are pointed out.

关键词： Inorganic electrode materials Potassium-ion batteries Cathode materials Anode materials

Natural sources,refined extraction,biosynthesis,metabolism,and bioactivities of dietary polymethoxyflavones(PMFs)

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Food Science and Human Wellness 2024年第1期13卷 27-49页

作者： Renyou Gan Yi Liu Hang Li Yu xia Huan Guo Fang geng Qiguo Zhuang Huabin Li Dingtao Wu Research Center for Plants and Human Health Institute of Urban AgricultureChinese Academy of Agricultural SciencesChengdu National Agricultural Science and Technology CenterChengdu 610213China Key Laboratory of Coarse Cereal Processing Ministry of Agriculture and Rural AffairsSichuan Engineering and Technology Research Centre of Coarse Cereal IndustralizationSchool of Food and Biological EngineeringChengdu UniversityChengdu 610106China China-New Zealand Belt and Road Joint Laboratory on Kiwifruit Sichuan Provincial Academy of Natural Resource SciencesChengdu 610213China Guangdong Provincial Key Laboratory of Food Nutrition and HealthSchool of Public HealthSun Yat-sen UniversityGuangzhou 510080China

Polymethoxyflavones(PMFs)are a type of uncommon dietary flavonoids,characterized by more than one methoxy group,which exist in limited plant species,like Citrus species and Kaempferia parviflora.In addition,different PMFs,such as nobiletin,sinensetin,tangeretin,and casticin,have been isolated from these natural sources.PMFs have received increasing attention due to their multiple bioactivities,such as antioxidant,anti-inflammatory,anti-cancer,metabolic regulatory,immunoregulatory,neuroprotective,and skin protective effects.These bioactivities of PMFs should be associated with the regulation of critical molecular targets and the interaction with gut microbiota.In order to provide a comprehensive and updated review of PMFs,their natural sources,refined extraction,biosynthesis,metabolism,and bioactivities are summarised and discussed,with the emphasis on the molecular mechanisms of PMFs on regulating different chronic diseases.Overall,PMFs may be promising flavonoids to the forefront of nutraceuticals for the prevention and/or treatment of certain human chronic diseases.

关键词： Nobiletin O-Methyltransferases Gut microbiota Bioactivities Molecular mechanism

新时代教材国家形象建构的逻辑起点、基本特征及实践进路

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现代教育管理 2024年第3期 85-97页

作者：耿希南京特殊教育师范学院江苏南京210038

教材是国家意志的体现,是国家形象建构的重要媒介。新时代教材国家形象建构是以实现社会主义现代化强国目标为逻辑起点,它不仅是中国式现代化话语深入教材建设的实践转化,还是教材建设强化新时代国家意识的核心要义,更是新时代教材推进... 详细信息

教材是国家意志的体现,是国家形象建构的重要媒介。新时代教材国家形象建构是以实现社会主义现代化强国目标为逻辑起点,它不仅是中国式现代化话语深入教材建设的实践转化,还是教材建设强化新时代国家意识的核心要义,更是新时代教材推进文化自信自强建设的自为选择。新时代教材国家形象建构的基本特征表现为:教材国家形象建构要素凸显强国特质,教材国家形象建构类型体现多元呼应以及教材国家形象建构结构呈现系统有序。新时代教材国家形象建构要坚持中国共产党的领导,明确教材国家形象建构目标定位;要以教材建设现代化为着力点,建立教材国家形象建构体系;要以教材体系高质量发展为主线,助推中国式教材国家形象现代化。

关键词：新时代教材国家形象建构中国式现代化国家意识国家治理

Command filtered integrated estimation guidance and control for strapdown missiles with circular field of view

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Defence Technology（防务技术） 2024年第5期35卷 211-221页

作者： Wei Wang Jiaqi Liu Shiyao Lin Baokui geng Zhongjiao Shi School of Aerospace Engineering Beijing Institute of TechnologyBeijing 10081China China Research and Development Academy of Machinery Equipment Beijing 100089China Northwest Industries Group CO. Ltd.Xi'an 710043China

In this paper,an integrated estimation guidance and control(IEGC)system is designed based on the command filtered backstepping approach for circular field-of-view(FOV)strapdown missiles.The threedimensional integrated estimation guidance and control nonlinear model with limited actuator deflection angle is established considering the seeker's FOV constraint.The boundary time-varying integral barrier Lyapunov function(IBLF)is employed in backstepping design to constrain the body line-of-sight(BLOS)in IEGC system to fit a circular FOV.Then,the nonlinear adaptive controller is designed to estimate the changing aerodynamic parameters.The generalized extended state observer(GESO)is designed to estimate the acceleration of the maneuvering targets and the unmatched time-varying disturbances for improving tracking accuracy.Furthermore,the command filters are used to solve the"differential expansion"problem during the backstepping design.The Lyapunov theory is used to prove the stability of the overall closed-loop IEGC system.Finally,the simulation results validate the integrated system's effectiveness,achieving high accuracy strikes against maneuvering targets.

关键词： Integrated estimation guidance and control Circular field-of-view Time-varying integral barrier Lyapunov function Command filtered backstepping control Nonlinear adaptive control Extended state observer

维普期刊数据库博看期刊

Stress relaxation properties of calcium silicate hydrate:a molecular dynamics study

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2024年第2期25卷 97-115页

作者： Zhicheng geng Shengwen TANG Yang WANG Hubao A Zhen HE Kai WU Lei WANG State Key Laboratory of Water Resources Engineering and Management Wuhan UniversityWuhan430072China Key Laboratory of Advanced Civil Engineering Materials of Ministry of Education School of Materials Science and EngineeringTongji UniversityShanghai200092China College of Materials Science and Engineering Xi’an University of Architecture and TechnologyXi’an710055China

The time-dependent viscoelastic response of cement-based materials to applied deformation is far from fully understood at the atomic level.Calcium silicate hydrate(C-S-H),the main hydration product of Portland cement,is responsible for the viscoelastic mechanism of cement-based materials.In this study,a molecular model of C-S-H was developed to explain the stress relaxation characteristics of C-S-H at different initial deformation states,Ca/Si ratios,temperatures,and water contents,which cannot be accessed experimentally.The stress relaxation of C-S-H occurs regardless of whether it is subjected to initial shear,tensile,or compressive deformation,and shows a heterogeneous characteristic.Water plays a crucial role in the stress relaxation process.A large Ca/Si ratio and high temperature reduce the cohesion between the calcium-silicate layer and the interlayer region,and the viscosity of the interlayer region,thereby accelerating the stress relaxation of C-S-H.The effect of the hydrogen bond network and the morphology of C-S-H on the evolution of the stress relaxation characteristics of C-S-H at different water contents was elucidated by nonaffine mean squared displacement.Our results shed light on the stress relaxation characteristics of C-S-H from a microscopic perspective,bridging the gap between the microscopic phenomena and the underlying atomic-level mechanisms.

关键词： Calcium silicate hydrate(C-S-H) Stress relaxation Ca/Si ratio Temperature Water content Atomic simulation