检索结果-南通市图书馆

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

PHOTOgRAPHER CHILEI

音乐大观 2008年第11期 74-85页

作者：池磊 xander Zhou

Tailoring the properties of quantum dot-micropillars by ultrafast optical injection of free charge carriers

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Light(Science & Applications) 2021年第11期10卷 2083-2097页

作者： Emanuel Peinke Tobias Sattler guilherme M.Torelly Patricia L.Souza Sylvain Perret Joel Bleuse Julien Claudon Willem L.vos Jean-Michel gerard Universitégrenoble Alpes CEAIRIG-PHELIQS“Nanophysique et Semiconducteurs”groupF-38000GrenobleFrance LabSem-CETUC Pontificia Universidade Catolica do Rio de JaneiroRio de Janeiro22451-900Brazil Complex Photonic Systems(COPS) MESA+Institute for NanotechnologyUniversity of TwenteP.O.Box 2177500 AEEnschedethe Netherlands

We review recent studies of cavity switching induced by the optical injection of free carriers in micropillar cavities containing quantum *** the quantum dots as a broadband internal light source and a streak camera as detector,we track the resonance frequencies for a large set of modes with picosecond time *** report a record-fast switch-on time constant(1.5 ps)and observe major transient modifications of the modal structure of the micropillar on the 10 ps time scale:mode crossings are induced by a focused symmetric injection of free carriers,while a lifting of several mode degeneracies is observed when off-axis injection breaks the rotational symmetry of the *** show theoretically and experimentally that cavity switching can be used to tailor the dynamic properties of the coupled QD-cavity *** report the generation of ultrashort spontaneous emission pulses(as short as 6 ps duration)by a collection of frequency-selected QDs in a switched pillar *** pulses display a very small coherence length,attractive for ultrafast speckle-free ***,the control of QD-mode coupling on the 10 ps time scale establishes cavity switching as an appealing resource for quantum photonics.

关键词： lifting injection cavity

Survival of encapsulated islets: More than a membrane story

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Transplantation 2016年第1期6卷 69-90页

作者： Uriel Barkai Avi Rotem Paul de vos Beta-O2 Technologies Rosh Ha Ayin Department of Pathology and Medical Biology Immunoendocrinology University of Groningen

At present, proven clinical treatments but no cures are available for diabetes, a global epidemic with a huge economic burden. Transplantation of islets ofLangerhans by their infusion into vascularized organs is an experimental clinical protocol, the first approach to attain cure. However, it is associated with lifelong use of immunosuppressants. To overcome the need for immunosuppression, islets are encapsulated and separated from the host immune system by a permselective membrane. The lead material for this application is alginate which was tested in many animal models and a few clinical trials. This review discusses all aspects related to the function of transplanted encapsulated islets such as the basic requirements from a permselective membrane(e.g., allowable hydrodynamic radii, implications of the thickness of the membrane and relative electrical charge). Another aspect involves adequate oxygen supply, which is essential for survival/performance of transplanted islets, especially when using large retrievable macrocapsules implanted in poorly oxygenated sites like the subcutis. Notably, islets can survive under low oxygen tension and are physiologically active at > 40 Torr. Surprisingly, when densely crowded, islets are fully functional under hyperoxic pressure of up to 500 Torr(> 300% of atmospheric oxygen tension). The review also addresses an additional category of requirements for optimal performance of transplanted islets, named auxiliary technologies. These include control of inflammation, apoptosis, angiogenesis, and the intra-capsular environment. The review highlights that curing diabetes with a functional bio-artificial pancreas requires optimizing all of these aspects, and that significant advances have already been made in many of them.

关键词： Bio-artificial pancreas Diabetes Islets of Langerhans Encapsulation Oxygen supply Permselective membrane Transplantation

Fecal microbiota transplantation as novel therapy in gastroenterology:A systematic review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of gastroenterology 2015年第17期21卷 5359-5371页

作者： Noortje g Rossen John K Mac Donald Elisabeth M de Vries geert R D'Haens Willem M de vos Erwin g Zoetendal Cyriel Y Ponsioen Department of gastroenterology and Hepatology Academic Medical Center Amsterdam1105 AZ AmsterdamThe Netherlands Division of gastroenterology Robarts Clinical trialsRobarts Research Institutethe University of Western OntarioLondonCanada and Amsterdamthe NetherlandsOntario N6A 5K8Canada Departments of Bacteriology and Immunology and Veterinary Biosciences University of HelsinkiFI-00014 HelsinkiFinland Laboratory of Microbiology Wageningen University6703 HA Wageningenthe Netherlands

AIM:To study the clinical efficacy and safety of Fecal microbiota transplantation(FMT).We systematically reviewed FMT used as clinical ***:We searched MEDLINE,EMBASE,the Cochrane Library and Conference proceedings from inception to July,*** effect of FMT was calculated as the percentage of patients who achieved clinical improvement per patient category,on an intention-to-treat ***:We included 45 studies;34 on Clostridium difficile-infection(CDI),7 on inflammatory bowel disease,1 on metabolic syndrome,1 on constipation,1 on pouchitis and 1 on irritable bowel syndrome(IBS).In CDI 90% resolution of diarrhea in 33 case series(n = 867) was reported,and 94% resolution of diarrhea after repeated FMT in a randomized controlled trial(RCT)(n = 16).In ulcerative colitis(UC) remission rates of 0% to 68% were found(n = 106).In Crohn's disease(CD)(n = 6),no benefit was *** IBS,70% improvement of symptoms was found(n = 13).100% Reversal of symptoms was observed in constipation(n = 3).In pouchitis,none of the patients(n = 8) achieved *** RCT showed significant improvement of insulin sensitivity in metabolic syndrome(n = 10).Serious adverse events were ***:FMT is highly effective in CDI,and holds promise in *** for CD,chronic constipation,pouchitis and IBS data are too limited to draw *** increases insulin sensitivity in metabolic syndrome.

关键词： Fecal microbiota transplantation Microbiota Clostridium difficile infection Inflammatory boweldisease Metabolic syndrome

Long-term live-cell microscopy with labeled nanobodies delivered by laser-induced photoporation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2020年第2期13卷 485-495页

作者： Jing Liu Tim Hebbrecht Toon Brans Eef Parthoens Saskia Lippens Chengnan Li Herlinde De Keersmaecker Winnok H.De vos Stefaan C.De Smedt Rabah Boukherroub Jan gettemans Ranhua Xiong Kevin Braeckmans Laboratory of general Biochemistry and Physical Pharmacy Faculty of PharmacyGhent UniversityGhent B-9000Belgium Department of Biomolecular medicine Faculty of Medicine and Health SciencesGhent UniversityGhent B-9000Belgium VIB-Ugent Center for Inflammation Research VIBGhent B-9000Belgium VIB Bioimaging Core ghent VIBGhent B-9000Belgium Department of Biomedical Molecular Biology Ghent UniversityGhent B-9000Belgium Univ.Lille CNRSCentrale LilleISENUniv.ValenciennesUMR 8520-IEMNLille F-59000Franc Laboratory of Cell Biology and Histology Department of Veterinary SciencesUniversity of Antwerp2020 AntwerpBelgium Centre for Advanced Light Microscopy Ghent UniversityGhent B-9000Belgium

Fluorescence microscopy is the method of choice for studying intracellular ***,its success depends on *** of specific and stable markers.A prominent example of markers that are rapidly gaining interest are nanobodies(Nbs.-15 kDa),which can be functionalized with bright and photostable organic *** to their relatively small size and high specificity,Nbs offer great potential for high-quality long-term subcellular imaging,but suffer from the fact that they cannot spontaneously cross the plasma membrane of live *** have recently discovered that laser-induced photoporation is well suited to deliver extrinsic labels to living cells without compromising their *** a laser-based technology,it is readily compatible with light microscopy and the typical cell recipients used for *** by these promising initial results,we demonstrate here for the first time successful long-term imaging of specific subcellular structures with labeled nanobodies in living *** illustrate this using Nbs that target gFP/YFP-protein constructs accessible in the cytoplasm,actin-bundling protein Fascin,and the histone H2A/H2B *** an efficiency of more than 80%labeled cells and minimal toxicity(-2%),photoporation proved to be an excellent intracellular delivery method for ***-lapse microscopy revealed that cell division rate and migration remained unaffected,confirming excellent cell viability and *** conclude that laser-induced photoporation labeled Nbs can be easily delivered into living cells,laying the foundation for further development of a broad range of Nbs with intracellular targets as a toolbox for long-term live-cell microscopy.

关键词： laser-induced photoporation vapor nanobubble long-term microscopy imaging nanobody intracellular delivery living cell labeling

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

厌氧好氧法处理漂白和染色废水

印染 2005年第2期31卷 47-51页

作者： C.T.M.J.Frijters R.H.vos g.Scheffer R.Mulder 荷兰帕克有限公司荷兰Ten Cute Protect纺织厂

荷兰帕克公司应用厌氧好氧连续工艺,成功处理了荷兰TenCate纺织厂的漂白和染色废水。该水处理工艺应用了容积为70m3的厌氧反应器和容积为450m3的好氧曝气池,废水色度去除率达80%～95%,且大部分色度是在预酸化池和厌氧反应器中去除的。... 详细信息

荷兰帕克公司应用厌氧好氧连续工艺,成功处理了荷兰TenCate纺织厂的漂白和染色废水。该水处理工艺应用了容积为70m3的厌氧反应器和容积为450m3的好氧曝气池,废水色度去除率达80%～95%,且大部分色度是在预酸化池和厌氧反应器中去除的。经厌氧好氧处理后的废水,对生物发光细菌Vibrofisheri无毒性。若使一部分废水不经过厌氧直接进入好氧进行处理,结果表明,好氧出水毒性增加,且色度去除率大大降低。这说明,厌氧处理对于废水的脱色和毒性去除起着重要的作用。

关键词：废水处理偶氮染料芳香族胺厌氧处理分散染料活性染料还原染料

维普期刊数据库

在线全文

学校读者我要写书评

暂无评论

大豆中glycinol的分离与鉴定

色谱 2005年第4期23卷 353-357页

作者：乞永艳 MOCO Sofia BOEREN Sjef de vos C H Ric BOVY Arnaud 中国农业科学院研究生院北京100081 Biochemistry Department of Wageningen University and Research Center Wageningen Netherlands Plant Research International Wageningen Netherlands

glycinol是大豆中主要的植物抗毒素和植物雌激素glyceollins的直接前体,是研究大豆中异戊烯转移酶必需的重要底物。该研究以新鲜大豆为原料,采用硝酸银诱导大豆子叶使glycinol在其中累积,再用甲醇提取,经制备高效液相色谱分离获得单一成... 详细信息

glycinol是大豆中主要的植物抗毒素和植物雌激素glyceollins的直接前体,是研究大豆中异戊烯转移酶必需的重要底物。该研究以新鲜大豆为原料,采用硝酸银诱导大豆子叶使glycinol在其中累积,再用甲醇提取,经制备高效液相色谱分离获得单一成分;经液相色谱/四极杆-飞行时间串联质谱及紫外光谱鉴定,并与标准品对照,确定所获得的单一成分为glycinol。采用该分离方法可从390g鲜重的大豆中分离得到100mg高纯度的glycinol。该研究提供了一种分离纯化和较大量制备glycinol的方法。

关键词：硝酸银制备高效液相色谱四极杆-飞行时间串联质谱 glycinol 大豆

维普期刊数据库

利用扩散MRI随访患注意力缺陷/多动症的男性病人在哌醋甲酯治疗后脑白质改变的随机对照试验

在线全文

学校读者我要写书评

暂无评论

国际医学放射学杂志 2019年第6期 739-740页

作者： C.Bouziane O.g.Filatova A.Schrantee M.W.A.Caan F.M.vos L.Reneman 张瀚 Departments of Radiology and Nuclear Medicine and Biomedical Engineering and Physics Amsterdam University Medical Centers location AMC University of Amsterdam

摘要目的在2011年10月13日—2015年6月15日之间,多动症转诊中心通过使用扩散张量成像(DTI)进行了一项随机双盲安慰剂对照试验[精神药物:哌醋甲酯(MPH)或

关键词：哌醋甲酯注意力缺陷多动症随机对照试验男性病人 MRI

培哚普利对冠状动脉粥样硬化进展的长期影响:PERSPECTIVE(血管造影及血管内超声评价培哚普利对冠状动脉粥样硬化的前瞻性作用)研究

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

世界核心医学期刊文摘（心脏病学分册） 2007年第12期3卷 18-19页

作者： Rodriguez-granillo g.A. vos J. Bruining N. P.J. De Feyter 罗亮 Department of Cardiology Thoraxcenter Erasmus MC RotterdamNetherlands.Dr

纳入12218例患者的多中心EUROPA试验表明,培哚普利可减少冠心病确诊患者的不良临床事件。PERSPECTIVE研究为EUROPA试验的一项亚研究,评估了培哚普利对冠状动脉粥样硬化斑块进展犤以定量冠状动脉血管造影和血管内超声(IVUS)评价犦的作用... 详细信息

纳入12218例患者的多中心EUROPA试验表明,培哚普利可减少冠心病确诊患者的不良临床事件。PERSPECTIVE研究为EUROPA试验的一项亚研究,评估了培哚普利对冠状动脉粥样硬化斑块进展犤以定量冠状动脉血管造影和血管内超声(IVUS)评价犦的作用。研究共纳入244例患者(平均年龄57岁,男性占81%)。自96例随机分配使用培哚普利的患者和98例使用安慰剂的患者获得了可供评估的成对定量冠状动脉血管造影资料。

关键词：冠状动脉粥样硬化安慰剂患者冠状动脉血管 PERSPECTIVE 空白剂培哚普利血管内超声

维普期刊数据库