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Science China Chemistry 2024年第3期67卷 908-913页

作者： Jun Zhang xuefeng wang Peiqi wang Jiayuan Fang Shaoyu Li Jie Wu School of Pharmaceutical and Chemical Engineering&Institute for Advanced Studies Taizhou UniversityShanghai 200438China Department of Chemistry Fudan UniversityShanghai 200438China State Key Laboratory of Organometallic Chemistry Shanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai 200032China School of Chemistry and Chemical Engineering Henan Normal UniversityXinxiang 453007China

β-Chiral sulfones are structural motifs widely found in natural products and bioactive molecules, while also serving as important intermediates for the synthesis of valuable chiral scaffolds. In contrast to the rapid growth of sulfur dioxide insertion chemistry over the last decade, enantioselective catalytic variants for accessing β-chiral sulfones, especially those bearing a quaternary carbon stereocenter, remain rare. Herein, we report an enantioselective copper/bisoxazoline catalyzed oxysulfonylation of alkenes to yield isoxazolinyl-containing β-chiral sulfones bearing quaternary carbon stereocenters with moderate to excellent yields and up to 96:4 er. The advantage and irreplaceability of this sulfur dioxide insertion catalytic system have been demonstrated by achieving transformations clearly unavailable with the previously reported sulfonyl chloride system. Additionally,the recoverability of the new-developed bisoxazoline ligand L9 and its reusability without any erosion of the catalytic activity and enantioselectivity further demonstrate the usefulness of the protocol.

关键词： β-chiral sulfones sulfur dioxide insertion oxysulfonylation copper catalysis enantioselectivity

Physics-informed deep Koopman operator for Lagrangian dynamic systems

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Science China(Information Sciences) 2024年第09期67卷 146-163页

作者： xuefeng wang Yang CAO Shaofeng CHEN Yu KANG Department of Automation University of Science and Technology of China State Key Laboratory of Fire Science University of Science and Technology of China Institute of Advanced Technology University of Science and Technology of China

Accurate mechanical system models are crucial for safe and stable control. Unlike linear systems,Lagrangian systems are highly nonlinear and difficult to optimize because of their unknown system *** research thus used deep neural networks to generate linear models of original systems by mapping nonlinear dynamic systems into a linear space with a Koopman observable function encoder. The controller then relies on the Koopman linear model. However, without physical information constraints, ensuring control consistency between the original nonlinear system and the Koopman system is tough, as the learning process of the Koopman observation function is unsupervised. This paper thus proposes a two-stage learning algorithm that uses structural subnetworks to build a physics-informed network topology to simultaneously learn the Koopman observable functions and the system energy representation. In the Koopman matrix learning session, a quadratic-constrained optimization problem is solved to ensure that the Koopman representation satisfies the energy difference matching hard constraint. The proposed energy-preserving deep Lagrangian Koopman(EPDLK) framework effectively represents the dynamics of the Lagrangian system while ensuring control consistency. The effectiveness of EPDLK is compared with those of various Koopman observable function construction methods in multistep prediction and trajectory tracking tasks. EPDLK achieves better control consistency by guaranteeing energy difference matching, which facilitates the application of the control law generated on the Koopman system directly to the original nonlinear Lagrangian system.

关键词： Koopman operator Lagrangian physics-informed nonlinear model predictive control (MPC)

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The underappreciated role of fugitive VOCs in ozone formation and health risk assessment emitted from seven typical industries in China

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Journal of Environmental Sciences 2024年第2期136卷 647-657页

作者： Zhiling Liang Yunjiang Yu Bingbing Sun Qian Yao Xihua Lin Yongsheng wang Jianping Zhang Yingzi Li xuefeng wang Zhengzheng Tang Shexia Ma College of Environmental and Chemical Engineering Shanghai University of Electric PowerShanghai 200090China State Environmental Protection Key Laboratory of Environmental Protection Health Risk Assessment South China Institute of Environmental SciencesMinistry of Ecology and EnvironmentGuangzhou 510535China Henan Jiyuan Ecological Environment Testing Center Jiyuan 454650China Ecological Environment Bureau of Jiyuan Production City Integration Demonstration Zone Jiyuan 454650China

Fugitive emission from industrial sources may result in ozone formation and health risk,while the exact contribution of this source remains incompletely *** this study,emission characteristics,ozone formation potential(OFP)and health risk of fugitive VOCs in7 representative industries were *** material industry was the dominant contributor to VOCs of fugitive emission in comparison with other *** OFP of VOCs from fugitive emission was in the range of 1.45×10^(3)-3.98×10^(5)μg/m^(3),with a higher value than that of organized emission in seven industries except for the coking industry and the chemical material industry,suggesting that fugitive VOCs should be taken into account while developing control ***,m,p-xylene,n-nonane,ethylene,vinyl chloridethe and other high OFP-contributing species were the major reactive species that should be *** risk assessment investigated non-cancer and cancer risks of fugitive VOCs in 7 industries were all above safe level(HR>1 and LCR>1×10^(-4)),posing remarkable health threats to human *** were the main contributor to non-cancer risk,while halohydrocarbons and aromatics contributed most to cancer risks,posing remarkable health threat on human *** findings highlighted the contribution of fugitive VOCs on ozone formation and health risk was underestimated,indicating which should be considered in emission control strategies of industrial sources.

关键词： Industrial sources Volatile organic compounds Fugitive emission Ozone formation potential Health risk assessment

COX-2 blocking therapy in cisplatin chemosensitization of ovarian cancer:An allicin-based nanomedicine approach

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Chinese Chemical Letters 2024年第8期35卷 449-454页

作者： Huijiao Fu Peiqin Liang Qianwen Chen Yan wang Guang Li Xuzi Cai Shengtao wang Kun Chen Shengying Shi Zhiqiang Yu xuefeng wang Department of Obstetrics and Gynecology The Third Affiliated Hospital of Southern Medical UniversityGuangzhou 510630China Department of Obstetrics and Gynecology Huizhou Central People’s HospitalHuizhou 516001China Affiliated Foshan Maternity&Child Healthcare Hospital Southern Medical University(Foshan Maternity&Child Healthcare Hospital)Foshan 528000China Guangdong Key Laboratory of New Drug Screening School of Pharmaceutical SciencesSouthern Medical UniversityGuangzhou 510515China Department of Nursing Nanfang HospitalSouthern Medical UniversityGuangzhou 510515China Department of Laboratory Medicine Dongguan Institute of Clinical Cancer ResearchThe Tenth Affiliated Hospital of Southern Medical University(Dongguan People’s Hospital)Dongguan 523018China

Recently,the utilization of nonsteroidal anti-inflammatory drugs(NSAIDs)to sensitize cisplatin(CDDP)has gained substantial traction in the treatment of ovarian cancer(OC).However,even widely employed NSAIDs such as celecoxib and naproxen carry an elevated risk of cardiovascular events,notably ***,the diminished sensitivity to CDDP therapy in OC is multifactorial,rendering the ap-plication of NSAIDs only partially effective due to their cyclooxygenase-2(COX-2)inhibiting ***,in this study,reactive oxygen species(ROS)-responsive composite nano-hydrangeas loaded with the Chinese medicine small molecule allicin and platinum(IV)prodrug(DTP@AP NPs)were prepared to achieve comprehensive *** one front,allicin achieved COX-2 blocking therapy,en-compassing the inhibition of proliferation,angiogenesis and endothelial mesenchymal transition(EMT),thereby mitigating the adverse impacts of CDDP ***,synergistic chemosensi-tization was achieved from multifaceted mechanisms by decreasing CDDP inactivation,damaging mito-chondria and inhibiting DNA *** essence,these findings provided an optimized approach for syner-gizing CDDP with COX-2 inhibitors,offering a promising avenue for enhancing OC treatment outcomes.

关键词： COX-2 blocking therapy CDDP Chemosensitization Allicin Ovarian cancer

Cationic ordering transition in oxygen-redox layered oxide cathodes

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Carbon Energy 2024年第1期6卷 197-206页

作者： Xinyan Li Ang Gao Qinghua Zhang Hao Yu Pengxiang Ji Dongdong Xiao xuefeng wang Dong Su Xiaohui Rong Xiqian Yu Hong Li Yong-Sheng Hu Lin Gu Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijingChina College of Materials Science and Opto-Electronic Technology University of Chinese Academy of SciencesBeijingChina Beijing National Center for Electron Microscopy and Laboratory of Advanced Materials School of Materials Science and EngineeringTsinghua UniversityBeijingChina Beijing Advanced Innovation Center for Materials Genome Engineering Huairou DivisionInstitute of PhysicsChinese Academy of SciencesBeijingChina

Understanding the structural origin of the competition between oxygen 2p and transition-metal 3d orbitals in oxygen-redox(OR)layered oxides is eminently desirable for exploring reversible and high-energy-density Li/Na-ion ***,we reveal the correlation between cationic ordering transition and OR degradation in ribbon-ordered P3-Na_(0.6)Li_(0.2)Mn_(0.8)O_(2) via in situ structural *** two different voltage windows,the OR capacity can be improved approximately twofold when suppressing the in-plane cationic ordering *** find that the intralayer cationic migration is promoted by electrochemical reduction from Mn^(4+)to Jahn–Teller Mn^(3+)and the concomitant NaO_(6) stacking transformation from triangular prisms to octahedra,resulting in the loss of ribbon ordering and electrochemical ***-principles calculations reveal that Mn^(4+)/Mn^(3+)charge ordering and alignment of the degenerate eg orbital induce lattice-level collective Jahn–Teller distortion,which favors intralayer Mn-ion migration and thereby accelerates OR *** findings unravel the relationship between in-plane cationic ordering and OR reversibility and highlight the importance of superstructure protection for the rational design of reversible OR-active layered oxide cathodes.

关键词： cationic ordering layered oxide cathodes oxygen redox sodium-ion batteries

Research and Application of Caideng Model Rendering Technology for Virtual Reality

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Journal of Computer and Communications 2024年第4期12卷 95-110页

作者： xuefeng wang Yadong Wu Yan Luo Dan Luo School of Automation and Information Engineering Sichuan University of Science & Engineering Yibin China College of Computer Science and Engineering Sichuan University of Science & Engineering Yibin China

With the development of virtual reality (VR) technology, more and more industries are beginning to integrate with VR technology. In response to the problem of not being able to directly render the lighting effect of Caideng in digital Caideng scenes, this article analyzes the lighting model. It combines it with the lighting effect of Caideng scenes to design an optimized lighting model algorithm that fuses the bidirectional transmission distribution function (BTDF) model. This algorithm can efficiently render the lighting effect of Caideng models in a virtual environment. And using image optimization processing methods, the immersive experience effect on the VR is enhanced. Finally, a Caideng roaming interactive system was designed based on this method. The results show that the frame rate of the system is stable during operation, maintained above 60 fps, and has a good immersive experience.

关键词： Virtual Reality Caideng Model Lighting Model Point Light Rendering

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铜基载氧体催化电厂烟气脱氧研究

燃料化学学报（中英文） 2024年第6期52卷 839-849页

作者：司马皓王雪峰邓存宝太原理工大学安全与应急管理工程学院山西太原030024

电厂烟气主要成分为N_(2)、CO_(2)和部分O_(2),将电厂烟气注入矿井采空区可实现CO_(2)封存,并替代注氮气防治遗煤自燃,但是烟气中的O_(2)是造成遗煤自燃的因素之一。因此,亟待开发一种经济有效的催化剂来脱除电厂烟气中的O_(2)。本研究... 详细信息

电厂烟气主要成分为N_(2)、CO_(2)和部分O_(2),将电厂烟气注入矿井采空区可实现CO_(2)封存,并替代注氮气防治遗煤自燃,但是烟气中的O_(2)是造成遗煤自燃的因素之一。因此,亟待开发一种经济有效的催化剂来脱除电厂烟气中的O_(2)。本研究采用共沉淀法,通过调变载体和负载量可控制备了铜基催化剂和系列xCuO/CeO_(2)催化剂,利用BET、XRD、ICP、TEM、H_(2)-TPR和XPS等手段对催化剂进行了表征,并建立催化剂结构与催化电厂烟气脱氧性能之间的构效关系。结果表明,CeO_(2)的加入提高了CuO的分散性、增加了催化剂的氧空位,提高了催化剂的活性和还原氧化性能,Cu-Ce界面结构的协同效应促进了还原氧化过程,表现出良好的活性和循环稳定性。30CuO/CeO_(2)由于其CuO颗粒尺寸最小、分散性最高、氧空位浓度最高,表现出较优的催化电厂烟气脱氧性能。本研究为开发低成本可循环使用、高活性和高稳定性的脱氧催化剂提供了参考。

关键词：化学链燃烧 CuO/CeO_(2) 氧化还原界面结构氧空位

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泡沫金属电磁感应传热机理研究

工程热物理学报 2024年第3期45卷 811-818页

作者：王雪锋徐峰冯上升生物医学信息工程教育部重点实验室西安交通大学生命学院西安710049 西安交通大学仿生工程与生物力学中心西安710049

研究了电磁感应加热下泡沫金属填充液体的磁–热能量转换及瞬态升/降温传热过程,搭建了泡沫金属填充液体在感应加热与液体冷却下的联合控温实验系统,采用“频域–瞬态”和“松耦合”方法求解电磁–传热耦合数值模型,揭示了泡沫金属填充... 详细信息

研究了电磁感应加热下泡沫金属填充液体的磁–热能量转换及瞬态升/降温传热过程,搭建了泡沫金属填充液体在感应加热与液体冷却下的联合控温实验系统,采用“频域–瞬态”和“松耦合”方法求解电磁–传热耦合数值模型,揭示了泡沫金属填充液体的电磁场与热源分布规律、温度响应特性、温度均匀性以及泡沫金属结构和材质等参数的影响规律。结果表明,泡沫金属填充液体的电磁感应传热特性与泡沫金属的结构和材质密切相关。

关键词：泡沫金属电磁-传热耦合频域-瞬态方法电磁加热

基于主题覆盖度的科研项目评审专家组推荐方法研究

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数据分析与知识发现 2024年第6期8卷 132-143页

作者：刘晓豫汪雪锋朱东华北京电子科技学院管理系北京100070 北京理工大学管理与经济学院北京100081

【目的】针对科研项目同行评议过程,测度专家知识对科研项目主题的覆盖,并通过主题覆盖度为科研项目推荐评审专家组。【方法】提出科研项目评审专家组推荐的三个原则:主题覆盖度最大原则、知识匹配度最大原则、工作量适宜原则。提出基于... 详细信息

【目的】针对科研项目同行评议过程,测度专家知识对科研项目主题的覆盖,并通过主题覆盖度为科研项目推荐评审专家组。【方法】提出科研项目评审专家组推荐的三个原则:主题覆盖度最大原则、知识匹配度最大原则、工作量适宜原则。提出基于Overlapping K-means的专家和待评审项目研究主题识别方法,以识别专家和待评审项目的一个或多个研究主题。以主题覆盖度最大为优化目标,提出基于主题覆盖度的专家组推荐模型,通过将推荐问题转化为优化问题,实现科研项目评审专家组的推荐。【结果】案例研究结果表明,通过本文方法构建的专家组在主题覆盖度上平均达到65.13%,相比于两组对照实验分别提高32.38个百分点和29.01个百分点。【局限】案例研究的样本量较为有限,未定量化探讨如何实现科研项目评审专家组推荐三个原则的多目标优化。【结论】本文提出的方法可以有效提高科研项目评审专家组对科研项目的主题覆盖度。

关键词：科研项目评审评审专家组专家推荐主题覆盖度

Safety of high-carbohydrate fluid diet 2 h versus overnight fasting before non-emergency endoscopic retrograde cholangiopancreatography:A single-blind,multicenter,randomized controlled trial

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Chinese Medical Journal 2024年第12期137卷 1437-1446页

作者： Wenbo Meng Joseph W.Leung Zhenyu wang Qiyong Li Leida Zhang Kai Zhang xuefeng wang Meng wang Qi wang Yingmei Shao Jijun Zhang Ping Yue Lei Zhang Kexiang Zhu Xiaoliang Zhu Hui Zhang Senlin Hou Kailin Cai Hao Sun Ping Xue Wei Liu Haiping wang Li Zhang Songming Ding Zhiqing Yang Ming Zhang Hao Weng QingyuanWu Bendong Chen Tiemin Jiang Yingkai wang Lichao Zhang Ke Wu Xue Yang Zilong Wen Chun Liu LongMiao Zhengfeng wang Jiajia Li Xiaowen Yan Fangzhao wang Lingen Zhang Mingzhen Bai Ningning Mi XianzhuoZhang Wence Zhou Jinqiu Yuan Azumi Suzuki Kiyohito Tanaka Jiankang Liu Ula Nur Elisabete Weiderpass Xun Li Department of General Surgery The First Hospital of Lanzhou UniversityLanzhouGansu 730000China Key Laboratory of Biological Therapy and Regenerative Medicine Transformation Gansu Province LanzhouGansu 730000China Division of Gastroenterology and Hepatology UC Davis Medical CenterSacramentoCA 95816USA Department of Minimally Invasive Surgery Tianjin Nankai HospitalTianjin 300100China Division of Hepatobiliary and Pancreatic Surgery Department of SurgeryShulan(Hangzhou)Hospital Affiliated to Zhejiang Shuren UniversityHangzhouZhejiang 310000China Department of Hepatobiliary Surgery Southwest HospitalArmy Medical UniversityChongqing 400000China Hepatobiliary Surgery Department Shandong Provincial Third HospitalJinanShandong 250000China Department of General Surgery Xinhua HospitalAffiliated to Shanghai Jiao Tong University School of MedicineShanghai Key Laboratory of Biliary Tract Disease ResearchShanghai 200000China Department of Hepatobiliary and Pancreatic Surgery The First Hospital of Jilin UniversityChangchunJilin 130000China Department of Hepatobiliary Surgery The General Hospital of Ningxia Medical UniversityYinchuanNingxia 750000China Department of Hepatobiliary&Hydatid Digestive and Vascular Surgery CenterXinjiang Key Laboratory of Echinococcosis and Liver Surgery ResearchThe First Affiliated Hospital of Xinjiang Medical UniversityUrumqiXinjiang 830000China Department of Hepatobiliary and Pancreatic Surgery The First Hospital of Shanxi Medical UniversityTaiyuanShanxi 030000China Department of General Surgery The Second Hospital of Lanzhou UniversityLanzhouGansu 730000China Department of Biliopancreatic Endoscopic Surgery The Second Hospital of Hebei Medical UniversityShijiazhuangHebei 050000China Gastrointestinal Surgery Department Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430000China Department of Hepatobiliary Surgery The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’anShaanxi 710000China Depart

Background:Although overnight fasting is recommended prior to endoscopic retrograde cholangiopancreatography(ERCP),the benefits and safety of high-carbohydrate fluid diet(CFD)intake 2 h before ERCP remain *** study aimed to analyze whether high-CFD intake 2 h before ERCP can be safe and accelerate patients’***:This prospective,multicenter,randomized controlled trial involved 15 tertiary ERCP centers.A total of 1330 patients were randomized into CFD group(n=665)and fasting group(n=665).The CFD group received 400 mL of maltodextrin orally 2 h before ERCP,while the control group abstained from food/water overnight(>6 h)before *** ERCP procedures were performed using deep sedation with intravenous *** investigators were blinded but not the *** primary outcomes included postoperative fatigue and abdominal pain score,and the secondary outcomes included complications and changes in metabolic *** outcomes were analyzed according to a modified intention-to-treat ***:The post-ERCP fatigue scores were significantly lower at 4 h(4.1±2.6 vs.4.8±2.8,t=4.23,P<0.001)and 20 h(2.4±2.1 vs.3.4±2.4,t=7.94,P<0.001)in the CFD group,with least-squares mean differences of 0.48(95%confidence interval[CI]:0.26-0.71,P<0.001)and 0.76(95%CI:0.57-0.95,P<0.001),*** 4-h pain scores(2.1±1.7 vs.2.2±1.7,t=2.60,P=0.009,with a least-squares mean difference of 0.21[95%CI:0.05-0.37])and positive urine ketone levels(7.7%[39/509]vs.15.4%[82/533],χ^(2)=15.13,P<0.001)were lower in the CFD *** CFD group had significantly less cholangitis(2.1%[13/634]vs.4.0%[26/658],χ^(2)=3.99,P=0.046)but not pancreatitis(5.5%[35/634]vs.6.5%[43/658],χ^(2)=0.59,P=0.444).Subgroup analysis revealed that CFD reduced the incidence of complications in patients with native papilla(odds ratio[OR]:0.61,95%CI:0.39-0.95,P=0.028)in the multivariable ***:Ingesting 400 mL of CFD 2 h before ERCP is safe,with a reduction in post-ERCP fatigue,

关键词： Endoscopic retrograde cholangiopancreatography ERCP Carbohydrate Fasting Safety Complications Enhanced recovery after surgery Randomized controlled trial