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Endoscopic full-thickness resection:A definitive solution for local complete resection of small rectal neuroendocrine neoplasms

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World Journal of Gastroenterology 2025年第10期31卷 51-61页

作者： Xiao-Long Zhang Yang-Yang jiang Ying-Ying chang Yu-Li Sun Ying Zhou Yao-Hui Wang Xiao-Tan Dou Hui-Min Guo Ting-Sheng Ling Digestive Endoscopy Center Affiliated Hospital of Nanjing University of Chinese MedicineJiangsu Province Hospital of Chinese MedicineNanjing 210029Jiangsu ProvinceChina Nanjing University of Chinese Medicine Nanjing 210029Jiangsu ProvinceChina Department of Pathology Affiliated Hospital of Nanjing University of Chinese MedicineJiangsu Province Hospital of Chinese MedicineNanjing 210029Jiangsu ProvinceChina Department of Gastroenterology Nanjing Drum Tower HospitalNanjing 210008Jiangsu ProvinceChina

BACKGROUND Recently,several endoscopic techniques have been used to improve the R0 resection rate of rectal neuroendocrine neoplasms(R-NENs).However,none of these methods can achieve 100%complete resection(CR),particularly in the vertical *** full-thickness resection(EFTR)has proven to be an effective method for the treatment of submucosal tumors but is seldom utilized in the eradication of *** To review cases of R-NENs removed using EFTR and to evaluate the safety and efficacy of this *** This retrospective cohort study enrolled 160 patients with pathologically confirmed R-NENs,including 132 who underwent endoscopic submucosal dissection(ESD)and 28 who underwent *** were categorized as2 cm in *** rate,en bloc resection rate,operation time,and complications were *** analyses and follow-up were also *** EFTR achieved 100%CR rates for lesions<1 cm and 1-2 cm,compared with 67.0%and 50.0%,respectively,in the ESD *** bloc resection and successful removal of the R-NENs were achieved in all ***,EFTR showed performance comparable to ESD in terms of operation time,hospitalization cost,and postoperative adverse events,except for a one-day longer hospital *** also analyzed the invasion depth of R-NENs based on full-thickness *** data showed that 80%of lesions(<1 cm)and 85.7%of lesions(1-2 cm)had invaded the SM3 level or deeper at the time of *** ESD specimens,46.6%(<1 cm)and 89.3%(1-2 cm)of lesions had infiltrated more than 2000μm beneath the muscularis *** EFTR has shown superior performance in the resection of small R-NENs compared with that of ESD.

关键词： Endoscopic full-thickness resection Endoscopic submucosal dissection Rectal neuroendocrine neoplasms Complete resection Endoscopic technique

基于土壤水分下限和作物耗水强度优化玉米阶段灌水量

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灌溉排水学报 2025年第1期44卷 17-24页

作者：梁雪薛冰李芳芳崔怡蕊马艳桃危常州姜艳石河子大学新疆石河子832003

【目的】基于土壤水分下限和作物耗水强度优化玉米阶段灌水量,为新疆玉米节水增产提供科学指导。【方法】以不同水分梯度下的膜下滴灌玉米为研究对象,研究新疆高产玉米在不同水分处理下的各生育时期适宜计划湿润层深度、耗水规律、产量... 详细信息

【目的】基于土壤水分下限和作物耗水强度优化玉米阶段灌水量,为新疆玉米节水增产提供科学指导。【方法】以不同水分梯度下的膜下滴灌玉米为研究对象,研究新疆高产玉米在不同水分处理下的各生育时期适宜计划湿润层深度、耗水规律、产量及水分利用效率,建立以土壤水分下限和作物耗水强度优化灌水量的方法。【结果】玉米拔节期适宜计划湿润层深度为20 cm,大喇叭口期、抽穗期和灌浆期为40 cm。660 mm灌水量下,DH618、XY335玉米品种的水分利用效率较高且产量显著高于其他灌水处理。基于土壤水分下限和作物耗水强度优化高产玉米阶段灌水量的结果为:DH618单次灌水量为51~70 mm,灌水总量为649.5 mm;XY335单次灌水量为39~67.5 mm,灌水总量为629.5 mm。【结论】基于土壤水分下限和作物耗水强度计算灌水量的方法从土壤和作物2个方面共同优化玉米阶段灌水量,更加科学性地分配了各阶段灌水量,提高了水分利用效率。

关键词：玉米土壤水分计划湿润层耗水规律耗水强度

Synthesis and Crystal Structure of 3-(4-Ethoxyphenyl)-6-(phenoxymethyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole

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Chinese Journal of Structural Chemistry 2007年第5期26卷 567-571页

作者： LEI Xin-Xiang LIU Miao-chang XIAO Hong-Ping ZHANG An-jiang ZHANG Li-xue School of Chemistry and Materials Engineering Wenzhou University Zhejiang 325027 China

The title compound C18H16N4O2S has been synthesized by the reaction of 4-amino-3-（4-ethoxyphenyl）-5-mercapto-1,2,4-triazole with phenoxyacetic acid in phospho- rus oxychloride, and characterized by IR, NMR spectra and elemental analysis. Its structure was determined by single-crystal X-ray diffraction. It crystallizes in monoclinic, space group P21/c with a = 1.4903（3）, b = 1.5230（2）, c = 0.9615（16） nm, Z = 4, V = 1.7769（5） nm^3, Dc = 1.317 g/cm^3, μ = 0.201 mm^-1, F（000） = 736, R = 0.0795 and wR = 0.2233. In the title compound, all rings are essentially planar.

关键词： X-ray diffraction crystal structure synthesis,spectral characterization thiadiazole

Room-Temperature Solution-Processed PbS Quantum Dot Solar Cells

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Chinese Journal of Chemistry 2020年第4期38卷 356-360页

作者： Yubin xue Shun-chang Liu Xinsheng Liu Yusi Yang Yimin Zhang Ding-jiang xue Jin-Song Hu Key Laboratory for Green Chemical Technology of Ministry of Education School of Chemical Engineering and TechnologyTianjin UniversityTianjin 300350China Beijing National Laboratory for Molecular Sciences(BNLMS) CAS Key Laboratory of Molecular Nanostructure and NanotechnologyInstitute of ChemistryChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China Key Laboratory for Special Functional Materials of Ministry of Education Henan UniversityKaifengHenon 475004China

Summary of main observation and conclusion Colloidal quantum dots(CQDs)are attractive absorber materials for highefficiency photovoltalcs be-cause of their facile solution processing,bandgap tunability due to quant um confinement effect,and multi-exciton *** date,all published performance records for PbS CQDs solar cells have been based on the conventional hot-injection synthesis *** method usually requires rela-tively strict conditions such as high temperature and the utilty of expensive source material pyrophoric bis(trimethylsilyl)sulfide(TM5-S),limiting the potential for large-scale and low-cost synthesis of Pbs *** we report a facile room-temperature synthetic method to produce high-quality Pbs CQDs through inexpensive ionic source materials including Pb NOl2 and Na:5 in the presence of triethanolamine(TEA)as the stabilizing *** PbS CQDs were successfully prepared with an average particle size of about 5 *** cells based on the as-synthesized PbS CQDs show a preliminary power conversion fficiency of 1.82%.This room-temperature and low-cost synth esis of PbS CQDs will further benefit the development of solution-processed CQD solar cells.

关键词： method. facile synthesis

Thermal acclimation of leaf respiration varies between legume and non-legume herbaceous

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Journal of Plant Ecology 2019年第3期12卷 498-506页

作者： Fei Peng chang Gyo Jung Lifen jiang Xian xue Yiqi Luo Northwest Institute of Eco-Environment and Resources Chinese Academy of SciencesLanzhouGansu 730000China International Platform for Dryland Research and Education Arid Land Research CenterTottori University1390 HamasakaTottori 680-0001Japan College of Engineering Forestryand Natural SciencesNorthern Arizona UniversityFlagstaffAS 86011USA

Aims Ubiquitous thermal acclimation of leaf respiration could mitigate the respiration ***,whether species of different plant functional groups showing distinct or similar acclimation justifies the simple prediction of respiratory carbon(C)loss to a warming *** In this study,leaf dark respiration(Rd)of illinois bundleflower(IB,legume),stiff goldenrod(GR,C_(3) forbs),indian grass,little bluestem and king ranch bluestem(IG,LB and KB,C_(4) grass)were measured with detached leaves sampled in a 17-year warming *** Findings The results showed that Rd at 20℃ and 22℃(R_(20) and R_(22))were significantly lower in the warming treatment for all the five *** R_(22) in warmed than R_(20) in control in GR,KB,LB and IG imply acclimation homeostasis,but not in *** significant decline in temperature sensitivity of respiration(Q_(10))of GR resulted in the marginal reduction of Q_(10) across *** significant changes in Q_(10) of C_(4) grasses suggest different acclimation types for C_(3) forbs and C_(4) *** magnitude of acclimation positively correlated with leaf C/*** results suggest that non-legume species had a rela-tive high acclimation,although the acclimation type was different between C_(3) forbs and C_(4) grasses,and the legume species displayed no acclimation in ***,the plant functional types should be taken into account in the grassland ecosystem C models.

关键词： acclimation dark respiration warming legume plant functional types

Construction of multi-homojunction TiO_(2)nanotubes for boosting photocatalytic hydrogen evolution by steering photogenerated charge transfer

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Nano Research 2023年第2期16卷 2259-2270页

作者： Jinbo xue Shan jiang Chengkun Lei Huan chang Jiaqi Gao Xuguang Liu Qi Li Qianqian Shen Key Laboratory of Interface Science and Engineering in Advanced Materials(Taiyuan University of Technology) Ministry of EducationTaiyuan 030024China Department of Chemistry Tsinghua UniversityBeijing 100084China College of Materials Science and Engineering Taiyuan University of TechnologyTaiyuan 030024China School of Materials Science and Engineering Southwest Jiaotong UniversityChengdu 610031China

As an effective means to improve charge carrier separation efficiency and directional transport,the gradient doping of foreign elements to build multi-homojunction structures inside catalysts has received wide ***,we reported a simple and robust method to construct multi-homojunctions in black TiO_(2) nanotubes by the gradient doping of Ni species through the diffusion of deposited Ni element on the top of black TiO2 nanotubes driven by a high temperature annealing *** gradient Ni distribution created parts of different Fermi energy levels and energy band structures within the same black TiO_(2) nanotube,which subsequently formed two series of multi-homojunctions within *** special multi-homojunction structure largely enhanced the charge carrier separation and transportation,while the low concentration of defect states near the surface layer further inhibited carrier recombination and facilitated the surface ***,the B-TNT-2Ni sample with the optimized Ni doping concentration exhibited an enhanced hydrogen evolution rate of~1.84 mmol·g^(−1)·h^(−1)under visible light irradiation without the assistance of noble-metal cocatalysts,~four times higher than that of the pristine black TiO_(2)nanotube *** the capability to create multi-homojunction structures,this approach could be readily applied to various dopant systems and catalyst materials for a broad range of technical applications.

关键词： Ni gradient-doped TiO_(2) multi-homogeneous junction energy band bending directional built-in electric field photocatalytic H_(2)evolution

白芍总苷对MPTP致帕金森病小鼠的作用机制

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中草药 2025年第4期56卷 1266-1276页

作者：薛慧铭冯真金畅王晶郑梅竹长春师范大学生命科学院长春师范大学中心实验室

目的探讨白芍总苷对1-甲基-4-苯基-1,2,3,6-四氢吡啶（1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine,MPTP）致帕金森病小鼠的保护机制。方法采用60%乙醇热回流法提取白芍总苷，高效液相色谱法测定白芍总苷化学成分。60只小鼠随机分... 详细信息

目的探讨白芍总苷对1-甲基-4-苯基-1,2,3,6-四氢吡啶（1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine,MPTP）致帕金森病小鼠的保护机制。方法采用60%乙醇热回流法提取白芍总苷，高效液相色谱法测定白芍总苷化学成分。60只小鼠随机分为对照组、模型组、美多芭（100 mg/kg）组和白芍总苷（total glucosides of paeony,TGP）低、中、高剂量（0.75、1.50、3.00 g/kg）组，各给药组ig给药（20 mL/kg），对照组、模型组ig等体积双蒸水（double-distilled water,ddH?O）,1次/d，连续15 d，自第8天起，对照组ip生理盐水，其他各组小鼠每天ip MPTP(30 mg/kg)。第15天ip MPTP 1 h后，检测小鼠的自主活动、滚轴能力及悬挂能力；免疫组织化学法检测各组小鼠黑质多巴胺能神经元的损伤情况，同时检测脑组织中单胺氧化酶-B(monoamine oxidase-B,MAO-B)活性水平、神经递质多巴胺（dopamine,DA）及其代谢产物3,4-二羟基苯乙酸（3,4-Dihydroxyphenylacetic acid,DOPAC）、高香草酸（homovanillic acid,HVA）；蛋白免疫印迹法检测多巴胺转运体（dopamine Transporter,DAT）、酪氨酸羟化酶（tyrosine Hydroxylase,TH）、脑源性神经营养因子（brain-derived neurotrophic factor,BDNF）、磷酸化环磷腺苷反应元件结合蛋白（phosphorylated cAMP-response element-binding protein,p-CREB）、环磷腺苷效应元件结合蛋白（cAMP-response element binding protein,CREB）、B淋巴细胞瘤-2基因（B-cell lymphoma-2,Bcl-2）、Bcl-2相关X蛋白（Bcl-2 associated X Protein,Bax）、裂解型半胱氨酸天冬氨酸蛋白酶-3(cleaved cystein-asparate protease-3,cleaved Caspase-3)蛋白表达水平。结果 MPTP诱导的帕金森病小鼠模型自发站立次数显著减少、悬挂能力和滚轴能力显著降低，显著降低黑质致密部TH阳性神经元数量；经高剂量白芍总苷处理后能显著增加小鼠的自发站立次数，提高滚轴能力（P<0.05）；显著增加TH阳性神经元数量（P<0.01），提高小鼠脑内的DA、HVA含量和DAT、TH、BDNF蛋白表达水平及p-CREB/CREB、Bcl-2/Bax的值（P<0.01），抑制小鼠脑内MAO-B、DOPAC、cleaved Caspase-3的表达（P<0.01）。结论白芍总苷高剂量组对MPTP诱导的小鼠损伤帕金森模型具有显著的保护作用，其作用机制可能与白芍总苷能够抑制MAO-B活性，提高DA及DAT、TH蛋白表达和激活CREB/BDNF及Bc1-2/Bax通路有关。

关键词：白芍总苷芍药苷帕金森病氧化应激作用机制单胺氧化酶-B 多巴胺转运体酪氨酸羟化酶

Bonding characteristics of the Al_2O_3-metal composite coating fabricated onto carbon steel by combustion synthesis

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International Journal of Minerals,Metallurgy and Materials 2014年第9期21卷 886-893页

作者： Xiao-feng xue Ze-hua Wang Ze-hua Zhou Shao-qun jiang jiang-bo Cheng chang-hao Wang Jia Shao College of Mechanics and Materials Hohai University

The fabrication of an alumina-metal composite coating onto a carbon steel substrate by using a self-propagating high-temperature synthesis technique was demonstrated. The effects of the type and thickness of the pre-coated layer on the binding structure and surface qual- ity of the coating were systematically investigated. The macrostructure, phase composition, and bonding interface between the coating and the substrate were investigated by scanning electronic microscopy （SEM）, X-ray diffraction （XRD）, and energy-dispersive X-ray spectrometry （EDS）. The diffraction patterns indicated that the coating essentially consisted of α-Al2O3, Fe（Cr）, and FeO-Al2O3. With an increase in the thickness of the pre-coated working layer, the coating became more smooth and compact. The transition layer played an important role in enhancing the binding between the coating and the substmte. When the pre-coated working layer was 10 mm and the pre-coated transition layer was 1 ram, a compact structure and metallurgical bonding with the substrate were obtained. Thermal shock test results indicated that the ceramic coating exhibited good thermal shock resistance when the sample was rapidly quenched from 800℃ to room temperature by plunging into water.

关键词： carbon steel combustion synthesis composite coatings phase composition morphology thermal shock resistance

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产教融合助力水稻企业财务数字化转型研究

北方水稻 2025年第1期55卷 69-74页

作者：薛媛常茹罗兰陕西财经职业技术学院会计学院陕西咸阳712000

水稻产业作为农业的重要组成部分,其数字化转型不仅关乎产业的可持续发展,更是推动农业现代化、提升国际竞争力的关键。为此,进行产教融合助力水稻企业财务数字化转型研究。研究中具体分析了水稻企业财务数字化转型的三种需求,即财务流... 详细信息

水稻产业作为农业的重要组成部分,其数字化转型不仅关乎产业的可持续发展,更是推动农业现代化、提升国际竞争力的关键。为此,进行产教融合助力水稻企业财务数字化转型研究。研究中具体分析了水稻企业财务数字化转型的三种需求,即财务流程繁琐、人员专业能力不足、自动化和智能化缺乏。为解决这三种需求,探索水稻企业财务数字化转型途径。通过产教融合,促进企业和教育机构之间的合作,共同开发RPA技术,优化了财务流程;通过产教融合,了解企业对数字化财务人才的具体需求,教学机构调整人才培养课程,同时共建“产教融合实训基地”,以企业为主导,以学校为辅助,开办培训机构;通过产教融合促进企业与高校、研究机构之间的合作,共同研发适合水稻企业的数字化财务管理系统和技术,实现财务数据的自动化和智能化挖掘和分析,帮助水稻企业作出更加科学的决策。

关键词：产教融合水稻企业财务需求分析 RPA技术人才培养技术创新数字化转型