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Induces Resistance Against Fusarium and Pink Rots by Acibenzolar-S-Methyl in Harvested Muskmelon (***)

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Agricultural Sciences in China 2008年第1期7卷 58-64页

作者： GE Yong-hong BI Yang li xuan li Mei College of Food Science and Engineering Gansu Agricultural University Lanzhou 730070 P.R.China

Acibenzolar-S-methyl （ASM） is a chemical activator of systematic resistance in many plants. The effect of preharvest and postharvest application of ASM was evaluated for its ability to induce resistance in muskmelon fruit. The results indicated that 50 and 100 mg L^-1 ASM or 1 mL L^-1 imazalil at 1 week or 1 day before harvest were effective in reducing the lesion area with 100 mg L^-1 ASM the most effective. No treatment inhibited the infection rate. The postharvest results showed that 50 and 100 mg L^-1 ASM, and 0.1 mL L^-1 imazalil were effective in reducing the lesion area with 100 mg L^-1 ASM the most effective. No treatment inhibited the infection rate. There was a clear time-dependent response of the fruit to postharvest ASM treatment, in which treatments applied 1, 3, and 5 day before inoculation provided the best results. ASM did not demonstrate any fungicide effect in vitro and suppressed lesion area in treated muskmelons, indicating that disease resistance was induced. The protection of ASM was associated with the activation of peroxidase （POD） in treated muskmelons.

关键词： acibenzolar-S-methyl (ASM) induced resistance muskmelon peroxidase (POD)

Synthesis and Anti-HIV Activity of Triazolo-fused 3 ＇,4＇-Cyclic and 4＇-Spiro Nucleoside Analogues

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Chemical Research in Chinese Universities 2013年第3期29卷 473-476页

作者： SUN Jing-bo liU Rong-wang xuan li-li LENG Wei-chun WU Jin-chang College of Chemistry Jilin University Changchun 130012 P. R. China China-Japan Union Hospital of Jilin University Changchun 130033 P. R. China

Triazolo-fused 3＇,4＇-cyclic nucleoside 4＇-spiro nucleoside analogues were synthesized by an intramolecular 1,3-dipolar cycloaddition of 4＇-azido nucleoside derived azido-alkynes in a regio- and stereo-specific manner. The thy- mine nucleoside base in these target compounds was transformed into the corresponding 5-methyl cytosine component. The synthesized compounds were examined in an MAGI（multinuclear-activation galactosidase indicator） assay for exploring the anti-HIV activity and in a H9 T（human T lymphocytes Hg） assay for measuring the cell toxicity.

关键词： 4'-Spiro nucleoside 3',4'-fused nucleoside Biological activity 1,3-Dipolar cycloaddition

Detection and Characterization of Non-covalent Complex between Lappaconitine and β-Cyclodextrin by Electrospray Ionization Tandem Mass Spectrometry

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Chinese Chemical Letters 2006年第1期17卷 65-68页

作者： Qing xuan XU li li Hao YUE Zhi Qiang liU Ming Quart GUO Shu Ying liU Laboratory of New Drug Research and Mass Spectrometry Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun 130022

The non-covalent complexes between lappaconitine （LA） and β-cyclodextrin （β-CD） have been detected and characterized by electrospray ionization combined with ion trap tandem mass spectrometry （ESI-MSn）. The experimental results showed that only 1：1 non-covalent complex can be formed in different starting molar ratios of LA to β-CD. Furthermore, the diagnostic fragmentation of the β-CD-LA complex, with a significant contribution of covalent fragmentation of LA leaving the N-acetyl anthranoyl （AN） moiety inserted to β-CD, provided the convincing evidence for the formation of non-covalent complex between LA and β-CD and the cite of LA molecule included to cavity of β-CD assigned to AN residue.

关键词： Lappaconitine β-cyclodextrin non-covalent complex ESI-MS CID.

Hydrography and Circulation in the Eastern Tropical Indian Ocean during April-May 2011

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Atmospheric and Oceanic Science Letters 2012年第4期5卷 284-289页

作者： xuan li-li QIU Yun XU Jin-Dian HE Yun-Kai Third Institute of Oceanography State Oceanic Administration Xiamen 361005 China State Key Laboratory of Tropical Oceanography South China Sea Institute of Oceanology The Chinese Academy of SciencesGuangzhou 510301 China

The distribution of hydrography and circulation in the eastern tropical Indian Ocean(ETIO) during April-May 2011 were analyzed using cruise observations,satellite observations,and historic hydrographic *** was observed that warm water(>28℃) occupies the upper 50-m layer in the ***-salinity surface water was observed at the mouth of the Bay of Bengal(BOB),which further extends to the Arabian Sea and off Sumatra via the Sri Lanka coast and the eastern bay *** Sea high-salinity water(ASHSW) is carried eastward along the equator to around 90°E by the equatorial undercurrent(EUC).It also runs south of Sri Lanka(north to 3°N) and in the western bay mouth(west to 87°E) but is much shallower than its counterpart at the *** is suggested to be the residual of the ASHSW,which intrudes into the BOB during the preceding southwest *** results also show that,in the south of Sri Lanka,just below this subsurface high-salinity water,very-low-salinity water(about 34.8) occurs at depths of 100-200 *** analysis suggests that this low-salinity water comes from the BOB.

关键词： eastern tropical Indian Ocean hydrography circulation

Cell polarization in ischemic stroke: molecular mechanisms and advances

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Neural Regeneration Research 2025年第3期20卷 632-645页

作者： Yuanwei li Xiaoxiao Xu xuan Wu Jiarui li Shiling Chen Danyang Chen Gaigai li Zhouping Tang Department of Neurology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

Ischemic stroke is a cerebrovascular disease associated with high mortality and disability rates. Since the inflammation and immune response play a central role in driving ischemic damage, it becomes essential to modulate excessive inflammatory reactions to promote cell survival and facilitate tissue repair around the injury site. Various cell types are involved in the inflammatory response, including microglia, astrocytes, and neutrophils, each exhibiting distinct phenotypic profiles upon stimulation. They display either proinflammatory or anti-inflammatory states, a phenomenon known as ‘cell polarization.’ There are two cell polarization therapy strategies. The first involves inducing cells into a neuroprotective phenotype in vitro, then reintroducing them autologously. The second approach utilizes small molecular substances to directly affect cells in vivo. In this review, we elucidate the polarization dynamics of the three reactive cell populations(microglia, astrocytes, and neutrophils) in the context of ischemic stroke, and provide a comprehensive summary of the molecular mechanisms involved in their phenotypic switching. By unraveling the complexity of cell polarization, we hope to offer insights for future research on neuroinflammation and novel therapeutic strategies for ischemic stroke.

关键词： astrocyte polarization immune regulation inflammation ischemic injury microglia polarization neutrophil polarization signaling pathways stroke

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改进粒子群优化BP神经网络的目标威胁估计

吉林大学学报（工学版） 2017年第3期47卷 996-1002页

作者：黄璇郭立红李姜于洋中国科学院长春光学精密机械与物理研究所长春130033 中国科学院大学北京100039

为了提高目标威胁估计精度,提出一种运用改进粒子群算法优化BP神经网络的方法。为了避免陷入局部极值,将变异过程引入粒子群算法中,并对相关参数进行优化,形成改进粒子群算法,对BP神经网络的初始权值和阈值进行优化。利用样本数量不同... 详细信息

为了提高目标威胁估计精度,提出一种运用改进粒子群算法优化BP神经网络的方法。为了避免陷入局部极值,将变异过程引入粒子群算法中,并对相关参数进行优化,形成改进粒子群算法,对BP神经网络的初始权值和阈值进行优化。利用样本数量不同的训练集对网络进行训练,并用60组测试集数据对网络进行验证。实验结果表明,改进粒子群优化BP神经网络目标威胁估计算法具有更高的预测精度,在训练样本数量较小时能够获得较好的预测能力,可以有效地完成目标威胁估计。

关键词：信息处理技术威胁估计粒子群优化算法 BP神经网络参数优化

Wafer-Scale Vertical 1D GaN Nanorods/2D MoS₂/PEDOT:PSS for Piezophototronic Effect-Enhanced Self-Powered Flexible Photodetectors

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NANO-MICRO LETTERS 2025年第1期17卷 1-15页

作者： Tang, Xin Jiang, Hongsheng lin, Zhengliang Wang, xuan Wang, Wenliang li, Guoqiang South China Univ Technol State Key Lab Luminescent Mat & Devices Guangzhou 510640 Peoples R China South China Univ Technol Sch Mat Sci & Engn Dept Elect Mat Guangzhou 510640 Peoples R China

Vertical 1D GaN nanorod arrays/2D MoS2/PEDOT:PSS heterostructures in wafer scale have been fabricated for flexible photodetection ***-powered flexible photodetector at compressive strain reveals a significantly enhanced photoresponse with a responsivity of 2.47 A W-1 and response times of 40/45 mu s, which are superior to the state-of-the-art flexible *** work not only provides a valuable strategy for the design and construction of tunable van der Waals heterostructures, but also opens a new opportunity for flexible sensors. van der Waals (vdW) heterostructures constructed by low-dimensional (0D, 1D, and 2D) materials are emerging as one of the most appealing systems in next-generation flexible photodetection. Currently, hand-stacked vdW-type photodetectors are not compatible with large-area-array fabrication and show unimpressive performance in self-powered mode. Herein, vertical 1D GaN nanorods arrays (NRAs)/2D MoS2/PEDOT:PSS in wafer scale have been proposed for self-powered flexible photodetectors arrays firstly. The as-integrated device without external bias under weak UV illumination exhibits a competitive responsivity of 1.47 A W-1 and a high detectivity of 1.2 x 1011 Jones, as well as a fast response speed of 54/71 mu s, thanks to the strong light absorption of GaN NRAs and the efficient photogenerated carrier separation in type-II heterojunction. Notably, the strain-tunable photodetection performances of device have been demonstrated. Impressively, the device at - 0.78% strain and zero bias reveals a significantly enhanced photoresponse with a responsivity of 2.47 A W-1, a detectivity of 2.6 x 1011 Jones, and response times of 40/45 mu s, which are superior to the state-of-the-art self-powered flexible photodetectors. This work presents a valuable avenue to prepare tunable vdWs heterostructures for self-powered flexible photodetection, which performs well in flexible sensors.

关键词： Vertical nanorod arrays van der Waals heterostructure Piezophototronic effect Self-powered photodetection Flexible sensors

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加热板形状对沥青混合料滚筒加热效率的影响

甘肃农业大学学报 2017年第4期52卷 182-187页

作者：马登成李旋李宗李平长安大学公路养护装备国家工程实验室陕西西安710064

【目的】通过仿真分析,研究不同形状的加热板对沥青混合料加热滚筒加热效率的影响,为沥青混合料加热滚筒加热板的选择提供理论依据.【方法】建立加热滚筒内部沥青混合料流场和加热板与沥青混合料间的传热数学模型,通过Fluent仿真软件建... 详细信息

【目的】通过仿真分析,研究不同形状的加热板对沥青混合料加热滚筒加热效率的影响,为沥青混合料加热滚筒加热板的选择提供理论依据.【方法】建立加热滚筒内部沥青混合料流场和加热板与沥青混合料间的传热数学模型,通过Fluent仿真软件建立平面板、凹形板、凸形板3种典型形状的加热板三维模型,分析不同加热板,加热滚筒对沥青混合料的加热效率.【结果】不同的加热板形状对加热滚筒加热效率有较大的影响,其中凹形加热板加热效率最高,并且加热均匀性最好;平面形加热板加热效率次之,凸形加热板加热效率最低.【结论】由于在实际工况中凹形板易发生回火,建议加热板设计为由4-6块弧度略小于180°的凸形板拼接组成的凹形圆弧加热板,这种加热板可有效提高加热效率.

关键词：加热板形状沥青混合料温度场仿真分析加热效率

腐殖酸与典型碳纳米材料协同光致产生活性氧物种的研究

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生态毒理学报 2016年第5期11卷 49-56页

作者：李绚李雪花陈景文工业生态与环境工程教育部重点实验室大连理工大学环境学院大连116024

采用电子自旋共振光谱（EPR）技术,分析腐殖酸在光照下对4种典型碳纳米材料诱导产生单线态氧（^1O2）和羟基自由基（·OH）的影响。基于密度泛函理论计算4种典型碳纳米材料的前线轨道能,比较了它们分别经能量转移诱导产生^1O2的能力以... 详细信息

采用电子自旋共振光谱（EPR）技术,分析腐殖酸在光照下对4种典型碳纳米材料诱导产生单线态氧（^1O2）和羟基自由基（·OH）的影响。基于密度泛函理论计算4种典型碳纳米材料的前线轨道能,比较了它们分别经能量转移诱导产生^1O2的能力以及经电子传递诱导产生·OH的能力。结果显示,4种不同形状的碳纳米材料（富勒烯、单壁碳纳米管、多壁碳纳米管以及石墨烯）悬浮液在紫外光照下均无^1O2和·OH产生。与腐殖酸共同存在下,4种碳纳米材料均显著诱导^1O2的产生,且富勒烯和石墨烯还能光致生成·OH。协同产生~1O2的能力大小为：单壁碳纳米管〉富勒烯〉多壁碳纳米管〉石墨烯,协同产生·OH的能力大小为：石墨烯〉富勒烯。^1O2的产生能力与碳纳米材料的能隙大小和颗粒聚集程度有关,而诱导产生·OH的能力主要取决于化学硬度。总之,我们的研究表明腐殖酸与碳纳米颗粒可协同产生活性氧物种。

关键词：碳纳米材料腐殖酸活性氧物种 EPR 能带结构