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Vascular reconstruction provides short-term and long-term survival benefits for patients with hilar cholangiocarcinoma:A retrospective,multicenter study

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Hepatobiliary & Pancreatic Diseases International 2024年第6期23卷 595-603页

作者： yi-Xian Huang Chao xu Cheng-Cheng Zhang Guang-yi Liu Xing-Chao Liu Hai-ning Fan Bi Pan Yuan-Cheng Li Department of Hepatobiliary Surgery Southwest HospitalThird Military Medical University(Army Medical University)Chongqing 400038China Department of Hepatobiliary Surgery Liaocheng People’s HospitalLiaocheng 252000China Sichuan Academy of Medical Sciences&Sichuan Provincial People’s Hospital Chengdu 610000China Qinghai University Affiliated Hospital Xining 810016China

Background:In patients with hilar cholangiocarcinoma(HCCA),radical resection can be achieved by resection and reconstruction of the ***,whether vascular reconstruction(VR)improves long-term and short-term prognosis has not been demonstrated ***:This was a retrospective multicenter study of patients who received surgery for HCCA with or without *** associated with overall survival(OS)and recurrence-free survival(RFS)were identified based on Cox ***-Meier curves were used to explore the impact of *** mean survival time(RMST)was used for comparisons of short-term survival between the ***’intraoperative and postoperative characteristics were ***:Totally 447 patients were *** divided these patients into 3 groups:VR with radical resections(n=84);non-VR radical resections(n=309)and non-radical resection(we pooled VRnonradical and non-VR nonradical together,n=54).Cox regression revealed that carbohydrate antigen 242(CA242),vascular invasion,lymph node metastasis and poor differentiation were independent risk factors for OS and *** was no significant difference of RMST between the VR and non-VR radical groups within 12 months after surgery(10.18 vs.10.76 mon,P=0.179),although the 5-year OS(Pning short-term survival compared with resection wit

关键词： Hilar cholangiocarcinoma Hepatectomy Vascular reconstruction Prognosis

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A Combination Model for Image Denoising

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Acta Mathematicae Applicatae Sinica 2016年第3期32卷 781-792页

作者： yi-ping xu School of Science Southwest University of Science and Technology

In this paper, we propose an efficient combination model of the second-order ROF model and a simple fourth-order partial differential equation （PDE） for image denoising. The split Bregman method is used to convert the nonlinear combination model into a linear system in the outer iteration, and an algebraic multigrid method is applied to solve the linear system in the inner iteration. Furthermore, Krylov subspace acceleration is adopted to improve convergence in the outer iteration. At the same time, we prove that the model is strictly convex and exists a unique global minimizer. We have also conducted a variety of numerical experiments to analyze the parameter selection criteria and discuss the performance of ~he fourth-order PDE in the combination model. The results show that our model can reduce blocky effects and our algorithm is efficient and robust to solve the proposed model.

关键词： image denoising partial differential equations split Bregman method algebraic multi-grid method Krylov subspace acceleration

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Breakthrough detection in electrochemical discharge drilling to enhance machining stability

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Chinese Journal of Aeronautics 2023年第6期36卷 460-475页

作者： Tianyu GENG Zhengyang xu Chenxiang ZHANG Jin ning College of Mechanical&Electrical Engineering Nanjing University of Aeronautics and AstronauticsNanjing 210016China

Film cooling holes are widely used in aero-engine turbine *** blades feature large numbers of holes with complex angles and require a high level of surface *** discharge drilling(ECDD)combines the high efficiency of electrical discharge drilling(EDD)with high quality of electrochemical drilling(ECD).However,due to the existence of a variety of energy for material removal,accurate and timely detection of breakthroughs is fraught with *** insufficient preset setting distance results in a tiny exit aperture,influencing the structure's *** addition,the electrode is prone to bending at a large overfeeding distance,causing secondary discharge damaging sidewall surface *** paper compares and analyzes the characteristics of processing waveforms using EDD and ECDD.A novel breakthrough detection method is proposed based on the variance signal of average voltage(VSAV)to increase machining stability and achieve fabrication without a recast *** method extracts the fluctuation transformation by calculating the variance of the *** signal detection,the overfeeding distance is *** experiment is used to validate the breakthrough detection with 100%accuracy in all *** optimum overfeeding distances for hole angles of 0°,30°,and 60° are obtained,and the stable removal of the recast layer is ***,the effectiveness of the method is verified on a typical workpiece with a double-wall structure and a nickel-based single crystal blade.

关键词： Change detection Electrochemical discharge drilling(ECDD) Electric discharge Film cooling holes Recast layer Variance signal of average voltage(VSAV)

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Microfluidic reactor with immobilized enzyme-from construction to applications:A review

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Chinese Journal of Chemical Engineering 2021年第2期34卷 136-145页

作者： Han Zhang Yunpeng Bai ning Zhu Jianhe xu State Key Laboratory of Bioreactor Engineering East China University of Science and TechnologyShanghai 200237China College of Biotechnology and Pharmaceutical Engineering Nanjing Tech UniversityNanjing211800China

Microfluidic,as the systems for using microchannel(micron-or sub-micron scale)to process or manipulate microflow,is being widely applied in enzyme biotechnology and *** immobilized enzyme reactor(MIER)is a tool with great value for the study of catalytic property and optimal reaction parameter in a flourishing and highly producing *** view of its advantages in efficiency,economy,and addressable recognition especially,MIER occupies an important position in the investigation of life science,including molecular biology,bioanalysis and biosensing,biocatalysis *** of enzymes can generally improve their stability,and upon most occasions,the immobilized enzyme is endowed with *** this review,the enzyme immobilization techniques applied in MIER will be discussed,followed by summarizing the novel developments in the field of MIER for biocatalysis,bioconversion and *** preponderances and deficiencies of the current state-of-the-art preparation ways of MIER are peculiarly *** addition,the prospects of its future study are outlined.

关键词： Microfluidic immobilized enzyme reactor Immobilization strategies Biocatalysis Bioconversion Bioanalysis

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Mechanical mechanism of overlying strata breaking and development of fractured zone during close-distance coal seam group mining

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International Journal of Mining Science and Technology 2020年第2期30卷 207-215页

作者： Jianguo ning Jun Wang Yunliang Tan Qiang xu College of Mining and Safety Engineering State Key Laboratory Breeding Base for Mining Disaster Prevention and ControlShandong University of Science and TechnologyQingdao 266590China

This study mainly investigates the mechanical mechanism of overlying strata breaking and the development of fractured zones during close-distance coal seam group mining in the Gaojialiang coal ***,a mechanical model for the second"activation"of broken overlying strata is established,and the related mechanical"activation"conditions are obtained.A recursive formula for calculating the separation distance of overlying strata is ***,a height determining method for predicting the height of fractured zones during close-distance coal seam group mining is proposed based on two values,namely,the separation distance and ultimate subsidence value of overlying *** method is applied to calculate the fractured zone heights in nos.20107 and 20307 mining *** calculated results are almost equal to the field observation ***,a modified formula for calculating the height of a waterflowing fractured zone is proposed.A comparison of the calculated and observed results shows that the errors are *** height determining method and modified formula not only build a theoretical foundation for water conservation mining at the Gaojialiang coal mine,but also provide a reference for estimating the height of water-flowing fractured zones in other coal mines with similar conditions.

关键词： Coal seam group Activation mechanism Separation Water-flowing fractured zone Modified formula

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Joint Communication-Caching-Computing Resource Allocation for Bidirectional Data Computation in IRS-Assisted Hybrid UAV-Terrestrial Network

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Chinese Journal of Electronics 2024年第4期33卷 1093-1103页

作者： Yangzhe LIAO Lin LIU Yuanyan SONG ning xu School of Information Engineering Wuhan University of Technology

Joint communication-caching-computing resource allocation in wireless inland waterway communications enables resource-constrained unmanned surface vehicles(USVs) to provision computation-intensive and latencysensitive tasks forward beyond fifth-generation(B5G) and sixth-generation(6G) era. The power of such resource allocation cannot be fully studied unless bidirectional data computation is properly managed. A novel intelligent reflecting surface(IRS)-assisted hybrid UAV-terrestrial network architecture is proposed with bidirectional tasks. The sum of uplink and downlink bandwidth minimization problem is formulated by jointly considering link quality, task execution mode selection, UAVs trajectory, and task execution latency constraints. A heuristic algorithm is proposed to solve the formulated challenging problem. We divide the original challenging problem into two subproblems, i.e., the joint optimization problem of USVs offloading decision, caching decision and task execution mode selection, and the joint optimization problem of UAVs trajectory and IRS phase shift-vector design. The Karush–Kuhn–Tucker conditions are utilized to solve the first subproblem and the enhanced differential evolution algorithm is proposed to solve the latter one. The results show that the proposed solution can significantly decrease bandwidth consumption in comparison with the selected advanced algorithms. The results also prove that the sum of bandwidth can be remarkably decreased by implementing a higher number of IRS elements.

关键词： Wireless communication Heuristic algorithms Bandwidth Network architecture Downlink Trajectory Resource management

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In-Cell Nanoelectronics:Opening the Door to Intracellular Electrophysiology

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Nano-Micro Letters 2021年第8期13卷 191-217页

作者： Dongxin xu Jingshan Mo Xi Xie ning Hu State Key Laboratory of Optoelectronic Materials and Technologies Guangdong Province Key Laboratory of Display Material and TechnologySchool of Electronics and Information TechnologySun Yat-Sen UniversityGuangzhou 510006People’s Republic of China The First Affiliated Hospital of Sun Yat-Sen University Guangzhou 510080People’s Republic of China State Key Laboratory of Transducer Technology Chinese Academy of SciencesShanghai 200050People’s Republic of China

Establishing a reliable electrophysiological recording platform is crucial for cardiology and neuroscience *** and label-free planar multitransistors and multielectrode arrays are conducive to perform the large-scale cellular electrical activity recordings,but the signal attenua-tion limits these extracellular devices to record subthreshold *** recent decade,in-cell nanoelectronics have been rapidly developed to open the door to intracellular *** the unique three-dimensional nanotopography and advanced penetration strategies,high-throughput and high-fidelity action potential like signal recordings is expected to be *** review summarizes in-cell nanoelectronics from versatile nano-biointerfaces,penetration strategies,active/pas-sive nanodevices,systematically analyses the applications in electrogenic cells and especially evaluates the influence of nanodevices on the high-quality intracellular electrophysiological ***,the opportunities,challenges and broad prospects of in-cell nanoelectronics are prospected,expecting to promote the development of in-cell electrophysiological platforms to meet the demand of theoretical investigation and clinical application.

关键词： In-cell nanoelectronics Nano-biointerfaces Intracellular electrophysiology Electrogenic cells

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STOCHASTIC COMPARISONS IN A PRICE-QUANTITY SETTING FIRM WITH UNCERTAIN DEMAND AND EMERGENCY PROCUREMENT

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Journal of Systems Science and Systems Engineering 2013年第4期22卷 401-420页

作者： Minghui xu Xiaolin xu yi-hui ZHOU School of Economics and Management Wuhan University School of Business Nanjing University Department of Biostatistics University of North Carolina

We consider a newsvendor problem with price-dependent demand, in either additive or multiplicative format. The newsvendor has two modes of purchasing： regular ordering at the beginning of the selling season and emergency ordering （if the realized demand exceeds the initial order quantity） at the end of the selling season. By stochastic comparisons, we systematically investigate the effects of demand magnitude and demand randomness on pricing and ordering quantity decisions as well as expected profit of the newsvendor, under both usual stochastic order （first order stochastic dominance） and convex order （less variable）. Our key findings include：（i） in contrary to the case where price is exogenous, a stochastically larger demand shock may even lead to a lower order quantity; （ii） a stochastically larger demand shock leads to a higher price for the additive demand case, but may lead to a lower price for the multiplicative demand case; （iii） a stochastically larger demand shock leads to a higher expected profit for both demand models; （iv） in general, a less variable demand leads to a higher expected profit for both demand models; and furthermore, a less variable demand shock has no effect on price for the additive demand model, but leads to a higher price for the multiplicative demand model. The implications of all these findings for pricing and order quantity are discussed in detail.

关键词： Price-dependent newsvendor stochastic comparison demand uncertainty pricing emergency supply option

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On hp refinements of independent cover numerical manifold method——some strategies and observations

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Science China(Technological Sciences) 2023年第5期66卷 1335-1351页

作者： ZHANG ning ZHENG Hong LI xu WU WenAn School of Civil Engineering Qinghai UniversityQinghai810016China Key Laboratory of Urban Security and Disaster Engineering Ministry of EducationBeijing University of TechnologyBeijing100081China Key Laboratory of Urban Underground Engineering of Ministry of Education Beijing Jiaotong UniversityBeijing100091China

In this paper,strategies are provided for a powerful numerical manifold method(NMM)with h and p refinement in analyses of elasticity and *** new NMM is based on the concept of the independent cover,which gets rid of NMM's important defect of rank deficiency when using higher-order local approximation *** techniques are *** terms of mesh generation,a relationship between the quadtree structure and the mathematical mesh is established to allow a robust *** to the condition number,a scaling based on the physical patch is much better than the classical scaling based on the mathematical patch;an overlapping width of 1%–10%can ensure a good condition number for 2nd,3rd,and 4th order local approximation functions;the small element issue can be overcome after the local approximation on small patch is replaced by that on a regular *** numerical accuracy,local approximation using complete polynomials is necessary for the optimal convergence *** issues that may damage the convergence rate should be *** first is to approximate the curved boundary of a higher-order element by overly few straight lines,and the second is excessive overlapping ***,several refinement strategies are verified by numerical examples.

关键词： independent cover numerical manifold method hp refinement partition of unity higher order element condition number

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Hybrid battery integrated by Zn-air and Zn-Co3O4 batteries at cell level

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Journal of Energy Chemistry 2020年第10期29卷 375-383页

作者： ning Liu Honglu Hu Xinxin xu Qiang Wang Department of Chemistry College of ScienceNortheastern UniversityShenyang 110819LiaoningChina Key Laboratory of Electromagnetic Processing of Materials MOENortheastern UniversityShenyang 110819LiaoningChina

The construction of Zn based hybrid battery through the combination of Zn-air and Zn-Co3O4 batteries at cell level is a feasible strategy to integrate high voltage,specific capacity and energy density in one power supply *** Zn based hybrid battery,an efficient cathode material with high specific capacitance and excellent ORR,OER activities is a vital component,which determines its performance in great *** this work,with Co based coordination polymer as precursor,oxygen vacancy-rich Co3 O4 based cathode material is *** this material Co3O4 particles with the size about 20 to 35 nm reside evenly in mesoporous carbon matrix doped by nitrogen *** OER,the overpotential of this cathode material is merely 330 m *** ORR proceeds with a typical four electron process with half wave achieving 0.76 *** charge/discharge at 1 A·g^-1,specific capacitance of this cathode material is 254.4 mAh·g^-*** current density increases to 20 A·g^-1,the specific capacitance still arrives at 122.5 mAh·g^-1 with nearly 50%*** on attractive performance of this cathode material,Zn based hybrid battery is *** discharge at 1 m A·cm-2,it presences two voltage platforms at 1.71 and 1.14 *** this situation,specific capacitance reaches 790 m Ah·g^-1 with energy density 928 Wh·kg^-*** battery shows promising stability after 300-cycle continuous test.

关键词： Zn based battery Hybrid battery Oxygen vacancy Electrocatalysis Co3O4

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