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FDTD for plasmonics:Applications in enhanced Raman spectroscopy

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Chinese Science Bulletin 2010年第24期55卷 2635-2642页

作者： YANG Zhilin li QianHong RUAN FangXiong li ZhiPeng REN Bin xu HongXing TIAN ZhongQun Department of Physics Xiamen University Xiamen 361005 China Institute of Physics Chinese Academy of Sciences Beijing 100190 China Department of Chemistry Xiamen University Xiamen 361005 China

The exact electromagnetic enhancement mechanism behind SERS,TERS,HERS and SHINERS is one of the issues focused on in the study of enhanced Raman *** three dimensional finite difference time domain method(3D-FDTD),which is widely used in nanoplasmonic simulations,not only provides us with a powerful numerical tool for theoretical studies of the ERS electromagnetic enhancement mechanism,but also serves as a useful tool for the design of ERS-active systems with higher sensitivities and spectral spatial *** this paper,we first introduce the fundamental principles of FDTD algorithms,and then the size-dependent dielectric function of dispersive metallic material is discussed.A comparative study of FDTD and rigorous Mie evaluations of electromagnetic fields in the vicinity of a system of self-similar nanospheres shows an excellent correlation between the two computational methods,directly confirming the validity and accuracy of 3D-FDTD simulations in ERS ***,we demonstrate,using a TERS calculation as an example,that the non-uniform mesh method can be more computationally efficient without loss of accuracy if it is applied correctly.

关键词：增强拉曼光谱 FDTD法应用时域有限差分法时域有限差分算法电磁增强机理 SERS效应有限差分模拟

Safety and clinical efficacy of linezolid in children:a systematic review and meta-analysis

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World Journal of Pediatrics 2023年第2期19卷 129-138页

作者： Yi Shi Hai-Lan Wu Yu-Hang Wu Shuang li li-Ya Zhang Shan-Shan xu He-Yu Huang Chun-Hong Zhang xu-Ben Yu Kang Cai Jing Zhang li-Su Huang Department of Infectious Disease Xinhua Children’s HospitalXinhua HospitalShanghai Jiao Tong University School of MedicineShanghai200092China National Clinical Research Center for Child Health Children’s HospitalZhejiang University School of MedicineHangzhou310052China Institute of Antibiotics Huashan HospitalFudan UniversityShanghai200040China Department of Pharmacy the First Affiliated Hospital of Wenzhou Medical UniversityWenzhou325000China

Background We aimed to evaluate the tolerability and efficacy of linezolid in children for treating suspected and diagnosed Gram-positive bacterial *** A systematic literature search was conducted up to April 23,2021,using linezolid and its synonyms as search *** reviewers independently identified and extracted relevant randomized controlled trials and prospective cohort *** extracted studies were included in a single-rate meta-analysis of adverse events and clinical outcomes using random-effects *** A total of 1082 articles were identified,and nine studies involving 758 children were included in the *** overall proportion of adverse events was 8.91%[95%confidence interval(CI)=1.64%–36.52%],with diarrhea(2.24%),vomiting(2.05%),and rash(1.72%)being the most *** incidences of thrombocytopenia and anemia were 0.68%and 0.16%,*** specific adverse events,including rash and gastrointestinal events,were more frequent in the oral administration *** terms of efficacy,the overall proportion of clinical improvement was 88.80%(95%CI=81.31%–93.52%).Children with a history of specific bacteriological diagnosis or concomitant antibiotic therapy had a 1.13-fold higher clinical improvement than children without such *** proportion of microbial eradication was 92.68%(95%CI=84.66%–96.68%).The proportion of all-cause mortality was 0.16%(95%CI=0.00%–7.75%).Conclusions linezolid was well-tolerated in pediatric patients and was associated with a low frequency of adverse events,such as anemia,thrombocytopenia,and ***,linezolid was effective in children with diagnosed and suspected Gram-positive infections.

关键词： Children Efficacy linezolid Meta-analysis Safety

Molecular distribution and seasonal variation of hydrocarbons in PM_(2.5) from Beijing during 2006

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Particuology 2013年第1期11卷 78-85页

作者： Yushan li Junji Cao Jianjun li Jiamao Zhou Hongmei xu Renjian Zhang Zhiyun Ouyang Research Center for Eco-Environmental Sciences Chinese Academy of Sciences University of Chinese Academy of Sciences Key Laboratory of Aerosol Science & Technology SKLLQGInstitute of Earth EnvironmentChinese Academy of Sciences Institute of Global Environmental Change Xi'an Jiaotong University Key Laboratory of Regional Climate-Environment Research for Temperate East Asia(RCE-TEA) Institute of Atmospheric PhysicsChinese Academy of Sciences

Normal （n）-alkanes and polycyclic aromatic hydrocarbons （PAHs） in PM2.5 were collected from Beijing in 2006 and analyzed using a thermal desorption-GC/MS technique. Annual average concentrations of n-alkanes and PAHs were 282 ±96 and 125 ± 150ng/m^3, respectively： both were highest in winter and lowest in summer. C19-C25 compounds dominated the n-alkanes while benzo[b]fluoranthene, benzo[e]pyrene, and phenanthrene were the most abundant PAHs. The n-alkanes exhibited moderate correlations with organic carbon （OC） and elemental carbon （EC） throughout the year, but the relation- ships between the PAHs, OC and EC differed between the heating and non-heating seasons. The health risks associated with PAHs in winter were more than 40 times those in spring and summer even though the PM2.5 loadings were comparable. Carbon preference index values （〈1.5） indicated that the n-alkanes were mostly from fossil fuel combustion. The ratios of indeno[123-cd]pyrene to benzo[ghi]pyrelene in summer and spring were 0.58 ± 0.12 and 0.63 ± 0.09, respectively, suggesting that the PAHs mainly originated from motor vehicles, but higher ratios in winter reflected an increased infuence from coal, which is extensively burned for domestic heating. A comprehensive comparison showed that PAH pollution in Beijing has decreased in the past 10 years.

关键词： PM2.5 Normal alkanes (n-alkanes) Polycyclic aromatic hydrocarbons (PAHs) Air pollution Beijing

Gevrey Well-Posedness of the Hyperbolic Prandtl Equations

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Communications in Mathematical Research 2022年第4期38卷 605-624页

作者： Wei-Xi li Rui xu School of Mathematics and Statistics Wuhan UniversityWuhan 430072China Hubei Key Laboratory of Computational Science Wuhan UniversityWuhan 430072China

We study 2D and 3D Prandtl equations of degenerate hyperbolic type,and establish without any structural assumption the Gevrey well-posedness with Gevrey index≤*** with the classical parabolic Prandtl equations,the loss of the derivatives,caused by the hyperbolic feature coupled with the degeneracy,cannot be overcame by virtue of the classical cancellation mechanism that developed for the parabolic *** by the abstract Cauchy-Kowalewski theorem and by virtue of the hyperbolic feature,we give in this text a straightforward proof,basing on an elementary L^(2)energy *** particular our argument does not involve the cancellation mechanism used efficiently for the classical Prandtl equations.

关键词： Hyperbolic Prandtl boundary layer well-posedness Gervey space abstract Cauchy-Kowalewski theorem

Design and test of soft-pot-tray automatic embedding system for light-economical pot seedling nursery machine

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International Journal of Agricultural and Biological Engineering 2020年第1期13卷 91-100页

作者： lintao Chen xu Ma Cong Wang Hongwei li Zehua li xueshen Chen Tao Chen College of Engineering South China Agricultural UniversityGuangzhou 510642China College of Mathematics and Informatics South China Agricultural UniversityGuangzhou 510642China

Most of the commercially-available pot seedling nursery machines are incompatible with soft-pot-trays and are labor-intensive and low in productivity.A soft-pot-tray automatic embedding system was developed in this study to achieve automatic embedding of the soft pot tray into the hard tray following sowing and covering with soil.A control system was constructed using the Arduino program development *** embedded-hard-tray automatic lowering mechanism and conveyor-belt-based pot-tray embedding system were *** analysis was conducted to derive an equation to describe the embedding process of the soft pot tray into the embedded hard tray.A prototype of the soft-pot-tray automatic embedding system was manufactured and *** analytical equation suggested that a minimum linear velocity of 0.86 m/s was required for a complete embedding *** experimental results showed that the embedded-hard-tray automatic lowering mechanism was reliable and stable as the tray placement success rate was greater than 99%.The successful tray embedding rate was 100%and the seed exposure rate was less than 1%with a linear velocity of the conveyor belt of 0.92 m/*** experiment findings agreed well with the analytical *** proposed soft-pot-tray automatic embedding system satisfied the technical specifications for a light-economical pot seedling nursery machine.

关键词： automatic embedding pot seedling nursery machine embedded hard tray soft pot tray conveyor-belt embedding system

Incidence, mortality, and temporal patterns of oropharyngeal cancer in China: a population-based study

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Cancer Communications 2018年第1期38卷 794-802页

作者： Jie liu xu-li Yang Si-Wei Zhang li-Ping Zhu Wan-Qing Chen Department of Chronic Non-Communicable Diseases Prevention Jiangxi Province Center for Disease Control and PreventionNanchangJiangxi 330029P.R.China The First Affiliated Hospital of Nanchang University NanchangJiangxi 330006P.R.China Office of Cancer Screening National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

Background:Thus far,the incidence,mortality,and temporal trend data of oropharyngeal cancers(OPC)in China were *** estimated the incidence,mortality,and temporal patterns of OPC in China during 2008-2012 according to the data from 135 population-based cancer registries to better understand the epidemiological pattern of OPC and to provide more precise information for OPC control in ***:According to the data of diagnosed OPC reported to 135 cancer registries during 2008-2012,we calcu-lated age-standardized rate of incidence and mortality by 2000 Chinese standard population(ASRIC and ASRMC)and by 1985 Segi’s world standard population(ASRIW and ASRMW)by age,sex,and geographic regions;annual percent-age changes of OPC incidence and mortality were calculated using Joinpoint trend ***:ASRIW and ASRMW were 2.22/100,000 person-years and 0.94/100,000 person-years,*** incidence and mortality in urban areas were higher than those in rural *** and ASRIW of males were higher than those of *** overall ASRIC of OPC was significantly increased by 6.2%annually between 2003 and 2006(P=0.038),but remained stable between 2007 and 2012(P=0.392).ASRIC and ASRMC of males and in rural areas were significantly increased in the last decade(P0.05).Conclusions:Across multiple cancer registries in China,there was an obvious increase in OPC in the recent decade,especially for incidence and mortality of males and in rural areas,whereas the rates of females remained stable.A healthy lifestyle should be advocated and early diagnosis and early treatment of OPC should be enhanced.

关键词： Oropharyngeal cancer Incidence Mortality Annual percentage change China

SmI_2-promoted imino-Reformatsky reaction for facile synthesis of enantioenriched β-amino acid esters

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Science China Chemistry 2011年第1期54卷 61-65页

作者： WANG li SHEN Chun xu Ming-Hua Shanghai Institute of Materia Medica Chinese Academy of Sciences Shanghai 201203 China

A facile and efficient method for the stereoselective synthesis of β-amino acid esters via SmI2-promoted imino-Reformatsky reaction is *** addition of tert-butyl bromoacetate to N-tert-butanesulfinyl aldimines afforded β-amino acid esters in moderate to high yields with excellent *** synthetic utilities of the tert-butyl β-amino acid esters were expanded by the preparation of β-lactams and 3-aminoindan-1-ones derivatives.

关键词： β-amino acid ester samarium diiodide N-tert-butanesulfinyl imine Reformatsky reaction β-lactam 3-aminoindan-1-one asymmetric synthesis

Deep-detection of formation boundary using transient multicomponent electromagnetic logging measurements

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Petroleum Science 2022年第3期19卷 1085-1098页

作者： Xi-Yong Yuan Shao-Gui Deng Zhi-Qiang li Xiao-Mei Han xu-Fei Hu Key Laboratory of Deep Oil and Gas China University of Petroleum(East China)QingdaoShandong266580China Sinopec Matrix Corporation QingdaoShandong266000China China Research Institute of Radiowave Propagation XinxiangHenan453000China China University of Petroleum—Beijing at Karamay KaramayXinjiang834000China

The maximum distance at which an electromagnetic(EM)logging while drilling(LWD)tool detects an approaching boundary is defined as the depth of detection(DOD).Ultra-deep detection capability of the transient multicomponent EM logging measurement is investigated ***,we adopt sine and cosine transform to calculate the transient multicomponent *** to the cosine transform,sine transform is more accurate in solving late-time ***,a time-domain geosignal is introduced to sense the *** show that DOD of this transient EM measurement can be up to tens of meters,including directionally ***,by studying the decay characteristics of different components with time,cross component is confirmed to decay much faster than the coaxial/coplanar components in the formation coordinate system.A pseudo-inversion is thereby proposed to determine the dip angle of anisotropic stratified *** simulation results indicate that this algebraic method can determine the true dip at some particular *** is still stable and valid even when considering random measurement ***,we establish the linear relationship between the time at which the half-point of geosignal curve appears and the distance to boundary(DTB),which would assist in the quick determination of DTB.

关键词： Time-domain Logging while drilling Formation boundary Dip angle Distance to boundary

Identification and expression of amphioxus AmphiSmad1/5/8 and AmphiSmad4

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Science China(life Sciences) 2011年第3期54卷 220-226页

作者： YU xueSong li JianWei liU Hui li XiaoDan CHEN ShangWu ZHANG HongWei xu AnLong State Key Laboratory of Biocontrol Open Laboratory for Marine Functional Genomics of State High- Tech Development Program Guangdong Key Laboratory of Pharmaceutical Functional Genes College of Life Sciences Sun Yat-Sen University Guangzhou 510275 China Institute of Developmental Biology College of Life Sciences Shandong University Jinan 250100 China

Smad family proteins are identified as intracellular signal mediators of the TGF-β *** this study,we identified two novel members of the Smad family,termed as AmphiSmad1/5/8 and AmphiSmad4,from Chinese *** AmphiSmad1/5/8 and AmphiSmad4 showed a typical domain structure of Smad proteins consisting of conserved MH1 and MH2 *** analysis placed AmphiSmad1/5/8 in the Smad1,5 and 8 subgroup of the R-Smad subfamily,and AmphiSmad4 in the Co-Smad *** spatial and temporal gene expression patterns of AmphiSmad1/5/8 and AmphiSmad4 showed that they may be involved in the embryonic development of notochord,myotome and alimentary canal,and may help to establish the specification of dorsal-ventral axis of ***,AmphiSmad1/5/8 and AmphiSmad4 showed extensive distribution in all adult tissues examined,suggesting that these two genes may play important roles in the morphogenesis of a variety of tissues especially notochord and gonad.

关键词： amphioxus Smad AmphiSmad1/5/8 AmphiSmad4 expression patterns organogenesis dorsal-ventral patterning