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生物炭改性及其对除草剂污染水体和土壤修复的研究进展

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化工进展 2024年第2期43卷 1069-1081页

作者：彭程徐漪琳石钰婧张玟李宇涛王皓冉张卫占绣萍华东理工大学国际卓越工程师学院上海200237 华东理工大学资源与环境工程学院上海200237 上海污染控制与生态安全研究院上海200092 上海市农业技术推广服务中心上海201103

除草剂已被大量使用于现代农业生产,而长期使用除草剂可能造成其在土壤中大量残留,或通过降水、淋溶和径流污染水体,因此引发环境污染问题和食品安全问题。生物炭作为一种绿色、高效的吸附剂已被广泛用于修复有机物污染水体和土壤。本... 详细信息

除草剂已被大量使用于现代农业生产,而长期使用除草剂可能造成其在土壤中大量残留,或通过降水、淋溶和径流污染水体,因此引发环境污染问题和食品安全问题。生物炭作为一种绿色、高效的吸附剂已被广泛用于修复有机物污染水体和土壤。本文介绍了酸碱、有机物和金属盐浸渍改性,纳米零价铁和微生物负载改性等生物炭改性方法;综述了改性生物炭在除草剂污染修复中的应用情况,对比分析了生物炭改性前后的修复效果;探讨了改性生物炭自身特性、环境条件对改性生物炭修复除草剂污染的影响及机制。未来仍需对改性生物炭在除草剂污染修复过程中的稳定性、长效性和安全性等方面开展研究。

关键词：改性生物炭除草剂纳米零价铁微生物修复效果吸附机理

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Method for Six-Legged Robot Stepping on Obstacles by Indirect Force Estimation

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Chinese Journal of Mechanical Engineering 2016年第4期29卷 669-679页

作者： xu yilin GAO Feng PAN Yang CHAI xun State Key Laboratory of Mechanical System and Vibration Shanghai Jiao Tong University

Adaptive gaits for legged robots often requires force sensors installed on foot-tips,however impact,temperature or humidity can affect or even damage those *** have been made to realize indirect force estimation on the legged robots using leg structures based on planar *** Octopus III is a six-legged robot using spatial parallel mechanism（UP-2UPS） *** paper proposed a novel method to realize indirect force estimation on walking robot based on a spatial parallel *** direct kinematics model and the inverse kinematics model are *** force Jacobian matrix is derived based on the kinematics ***,the indirect force estimation model is ***,the relation between the output torques of the three motors installed on one leg to the external force exerted on the foot tip is ***,an adaptive tripod static gait is *** robot alters its leg trajectory to step on obstacles by using the proposed adaptive *** the indirect force estimation model and the adaptive gait are implemented and optimized in a real time control *** experiment is carried out to validate the indirect force estimation *** adaptive gait is tested in another *** results show that the robot can successfully step on a 0.2 m-high *** paper proposes a novel method to overcome obstacles for the six-legged robot using spatial parallel mechanism legs and to avoid installing the electric force sensors in harsh environment of the robot＇s foot tips.

关键词： robot parallel mechanism force estimation obstacle

不同硬度地面对功能性踝关节不稳患者步态协调性的影响

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中国康复理论与实践 2024年第3期30卷 345-351页

作者：马乾峰李立张伟丁健许贻林毛文慧南京师范大学体育科学学院江苏南京市210023 美国佐治亚南方大学运动健康科学系美国佐治亚州30460 江苏省体育科学研究所江苏南京市210033

目的探索不同硬度地面对功能性踝关节不稳(FAI)患者步态协调性的影响。方法 2023年5月至7月,采用Qualisys红外光学运动捕捉系统对南京师范大学15例右侧FAI患者协调性和变异性进行测试。采集并截取步态周期数据,运用Matlab计算耦合角和... 详细信息

目的探索不同硬度地面对功能性踝关节不稳(FAI)患者步态协调性的影响。方法 2023年5月至7月,采用Qualisys红外光学运动捕捉系统对南京师范大学15例右侧FAI患者协调性和变异性进行测试。采集并截取步态周期数据,运用Matlab计算耦合角和耦合角标准差,比较在不同硬度地面上的差异。结果在冠状面,髋-踝关节耦合角在支撑中期和支撑后期硬地面大于软地面,其他步态阶段以及髋-膝关节、膝-踝关节各步态阶段均小于软地面(P <0.05);在矢状面,髋-踝关节和膝-踝关节耦合角在支撑中期和支撑后期硬地面小于软地面,其他步态阶段以及髋-膝关节各步态阶段均大于软地面(P <0.01);在水平面,髋-膝关节耦合角在支撑后期硬地面小于软地面,摆动前期和髋-踝关节承重期均大于软地面(P <0.05)。与硬地面相比,软地面上耦合角标准差仅在矢状面髋-膝关节承重期小于硬地面,其余均大于硬地面(P <0.05)。结论 FAI患者在三维面内各步态阶段在软地面上表现出更多的远端主导,即踝关节内翻跖屈优势增加,髋关节优势减少;协调变异性普遍高于硬地面。表明FAI患者在软地面上步行时会增加复发性外踝扭伤风险。

关键词：功能性踝关节不稳地面硬度步态协调模式协调变异性

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青藤碱药理作用及临床应用的研究进展

华西药学杂志 2024年第2期39卷 209-215页

作者：徐易琳黄莉周莉莉邹蔓姝莫美霞夏新华湖南中医药大学药学院湖南长沙410208 湖南中医药大学第一附属医院湖南长沙410007

青藤碱具有抗炎、免疫抑制、抗肿瘤、镇痛等多种药理作用,但存在生物利用度低、药效持续时间短、用药剂量大等局限性。现综述青藤碱的药理作用、临床应用及新剂型的研究,为其研究提供参考。

关键词：青藤碱青风藤药理作用临床应用抗炎类风湿性关节炎研究进展

Obstacle avoidance for a hexapod robot in unknown environment

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Science China(Technological Sciences) 2017年第6期60卷 818-831页

作者： CHAI xun GAO Feng QI ChenKun PAN Yang xu yilin ZHAO Yue State Key Laboratory of Mechanical System and Vibration Shanghai Jiao Tong University Shanghai 200240 China'

Obstacle avoidance is quite an important issue in the field of legged robotic applications, such as rescuing and detecting in complicated environment. Most related researchers focused on the legged robot’s gait generation after ssuming that obstacles have been detected and the walking path has been given. In this paper we propose and validate a novel obstacle avoidance framework for a six-legged walking robot Hexapod-III in unknown environment. Throughout the paper we highlight three themes: (1) The terrain map modeling and the obstacle detection; (2) the obstacle avoidance path planning method; (3) motion planning for the legged robot. Concretely, a novel geometric feature grid map (GFGM) is proposed to describe the terrain. Based on the GFGM, the obstacle detection algorithm is presented. Then the concepts of virtual obstacles and safe conversion pose are introduced. Virtual obstacles restrict the robot to walk on the detection terrain. A safe path based on Bezier curves, passing through safe conversion poses, is obtained by minimizing a penalty function taking into account the path length subjected to obstacle avoidance. Thirdly, motion planning for the legged robot to walk along the generated path is discussed in detail. At last, we apply the proposed framework to the Hexapod-III robot. The experimental result shows that our methodology allows the robot to walk safely without encountering with any obstacles in unknown environment.

关键词： obstacle avoidance hexapod robot terrain map building path planning motion planning

Effects of biochar carried microbial agent on compost quality,greenhouse gas emission and bacterial community during sheep manure composting

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Biochar 2023年第1期5卷 42-58页

作者： Zhe Wang yilin xu Tong Yang Yongqi Liu Tingting Zheng Chunli Zheng School of Energy and Environment Inner Mongolia University of Science and TechnologyBaotou 014010China Inner Mongolia Engineering Research Center of Evaluation and Restoration in the Mining Ecological Environment Inner Mongolia University of Science and Technology014010 BaotouChina

Although composting is a very effective way to dispose agricultural wastes,its development is greatly limited by the low compost quality and greenhouse gas *** present,there is a lack of effective means to solve these two problems ***,the effects of three additives of compound microbial agent,biochar and biochar carried microbial agent on the composting performance,nitrogen transformation,greenhouse gas and ammonia emissions,and bacterial communities were investigated in sheep manure composting during 28 *** showed that biochar carried microbial agent prolonged the thermophilic stage and promoted compost *** the same time,it was confirmed by the increase of the decomposition of organic nitrogen and the transformation of NH_(4)^(+)-N to NO_(3)^(−)-***,adding biochar carried microbial agent decreased CH_(4),NH_(3) and N_(2)O emissions by 65.23%,42.05%and 68.64%,*** gas emissions were mainly correlated to Chloroflexi,Myxococcota,Acidobacteriota,Firmicutes,and *** analysis showed that EC and TKN were closely related to bacterial ***,biochar carried microbial agent is recommended as an effective additive to enhance compost quality and reduce gas emissions during sheep manure composting.

关键词： Biochar carried microbial agent Sheep manure Composting Nitrogen transformation Bacterial community Greenhouse gases

Single-Nucleus RNA Sequencing Reveals Cardiac Macrophage Landscape in Hypoplastic Left Heart Syndrome

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Congenital Heart Disease 2024年第2期19卷 233-246页

作者： Xiaozhuo xu yilin Huang xu Han First Clinical Medical College Affiliated Hospital of Nanjing University of Chinese MedicineNanjing210008China Department of Geriatrics Affiliated Hospital of Nanjing University of Chinese MedicineNanjing210029China

Background:Hypoplastic left heart syndrome(HLHS)is one of the most challenging congenital heart diseases in clinical *** cardiac tissues,resident macrophages fulfill critical functions in maintaining a stable cardiac state and have strong regenerative capacity and organ ***,the molecular mechanisms of macro-phages in HLHS remained ***:Single-nucleus RNA sequencing(snRNA-seq)data of HLHS and healthy control(donors)samples obtained from the Gene Expression Omnibus(GEO)database were normalized and clustered using the Seurat ***“FindMarkers”function was used to screen differentially expressed genes(DEGs)between the HLHS and donor groups and to analyze the functional enrichment of the set of genes of ***,cell-cell communication,pseudotime,and single-cell regulatory network inference and cluster-ing(SCENIC)analyses were used to study the mechanisms of macrophages in ***:Based on the snRNA-seq data of HLHS and donors,we identified a total of 9 cell clusters,among which the proportion of macrophages was significantly less in the HLHS group than in the control *** of macrophage subpopulations(Macrophages 1,2,and 3)showed that Macrophages 1 was mainly involved in nervous system development,angiogenesis,and apoptotic *** addition,analysis of communication between Macro-phages 1 and cardiomyocytes revealed that ligand-acceptor pairs such as GAS6/AXL,IL6,IGF1,THY1,and L1CAM were present only in the donor ***,pesudotime and SCENIC analyses demonstrated that FOXO3 and ELF2 played a critical role for Macrophages 1 to maintain cardiac function in patients with ***:Our study improved the current understanding of the molecular mechanisms of macrophage devel-opment in HLHS,showing that manipulating the regulatory role of macrophages in the heart can be a novel treat-ment for HLHS.

关键词： Hypoplastic left heart syndrome single-nucleus RNA sequencing macrophage cellular subpopulation transcription factor

冠心病患者经皮冠状动脉介入术后自我管理能力的影响因素分析及列线图模型构建

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实用临床医药杂志 2024年第15期28卷 101-104,109页

作者：杨学芹孙彩凤徐艺琳王东霞江苏省淮安市第二人民医院全科医学科江苏淮安223300

目的分析冠心病患者经皮冠状动脉介入术(PCI)治疗后自我管理能力的影响因素并构建列线图模型。方法选取行PCI治疗的247例冠心病患者作为研究对象,均接受冠心病自我管理行为量表(CSMS)评估。通过多因素Logistic回归分析筛选出冠心病患者... 详细信息

目的分析冠心病患者经皮冠状动脉介入术(PCI)治疗后自我管理能力的影响因素并构建列线图模型。方法选取行PCI治疗的247例冠心病患者作为研究对象,均接受冠心病自我管理行为量表(CSMS)评估。通过多因素Logistic回归分析筛选出冠心病患者PCI治疗后自我管理能力的独立影响因素,应用R软件构建列线图模型,采用受试者工作特征(ROC)曲线、校准曲线和Hosmer-Lemeshow拟合优度检验评估列线图模型的区分度、校准度和拟合效度。结果247例患者的平均CSMS评分为(86.79±9.22)分,以86.79分为临界值将患者分为低分组89例、高分组158例;低分组年龄、受教育程度、家庭人均月收入、自我效能与高分组比较,差异有统计学意义(P70岁增加86.2分权重,受教育程度为高中以下增加87.4分权重,家庭人均月收入<3500元人民币增加82.3分权重,自我效能较低增加99.6分权重。ROC曲线分析结果显示,列线图模型预测冠心病患者PCI治疗后自我管理能力的曲线下面积为0.842(95%CI:0.794~0.890);校准曲线斜率接近1,拟合优度检验χ^(2)=10.226、P=0.233。结论年龄、受教育程度、家庭人均月收入、自我效能为冠心病患者PCI治疗后自我管理能力的影响因素,据此构建的列线图模型对自我管理能力具有较高的预测价值。

关键词：冠心病经皮冠状动脉介入术自我管理列线图模型

Five‑year outcomes of EVO implantable collamer lens implantation for the correction of high myopia and super high myopia

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Eye and Vision 2021年第1期8卷 404-411页

作者： xun Chen xuanqi Wang yilin xu Mingrui Cheng Tian Han LingLing Niu Xiaoying Wang Xingtao Zhou Fudan University Eye Ear Nose and Throat Hospital No.19 BaoQing RoadXuHui DistrictShanghai 200031China National Health Commission Key Lab of Myopia(Fudan University) ShanghaiChina Shanghai Research Center of Ophthalmology and Optometry ShanghaiChina

Background:To evaluate the long-term safety,efficacy,predictability,and stability of implantable collamer lens with a central hole(EVO ICL)implantation for correcting high myopia(HM)and super high myopia(SHM).Methods:This prospective study evaluated 83 eyes of 46 patients who were divided into groups based on their spherical equivalent refractive error(SE):HM group(−12 D≤SE<−6 D)and SHM group(SE<−12 D).They were followed up for 5 years after ICL implantation;assessments of uncorrected distance visual acuity(UDVA),corrected distance visual acuity(CDVA),manifest refractive error,axial length,intraocular pressure,corneal endothelial cell density,and vault were conducted,and a questionnaire was ***:At 5 years postoperatively,the safety indices of the HM and SHM groups were 1.03±0.10 and 1.32±0.39,and the efficacy indices were 0.83±0.25 and 0.86±0.32,*** the HM group,60.47%and 79.07%of the eyes were within±0.50 D and±1.00 D of the attempted correction,while it was achieved for 22.50%and 47.50%of the eyes in the SHM group,*** SE of the HM group decreased from−9.72±1.41 D preoperatively to 0.04±0.39 D 1 month postoperatively and−0.67±0.57 D 5 years postoperatively,while in the SHM group,it decreased from−15.78±3.06 D preoperatively to−0.69±0.97 D 1 month postoperatively and−1.74±1.19 D 5 years ***:EVO ICL implantation is safe,effective,and predictable for correcting HM and *** improved more after surgery for SHM,but the growth of axial length still needs attention.

关键词： Posterior chamber phakic intraocular lens implantation High myopia Super high myopia EVO ICL