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中国现代伦理形态的发展与建构——基于梁启超新民伦理的研究

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内蒙古社会科学 2024年第1期45卷 115-121页

作者：徐亚州谢桂山中共山东省委党校(山东行政学院)哲学教研部山东济南250103 山东社会科学院法学研究所山东济南250002

随着西方现代思想理论在中国近代场域的深入传播,梁启超展开了对中国传统伦理道德观念的反思性审视,开启了寻求社会现代化和新民人格的实践探索。梁启超主张伦理观念应当积极适应现代社会的发展需求,强调传统儒家伦理学和现代西方伦理... 详细信息

随着西方现代思想理论在中国近代场域的深入传播,梁启超展开了对中国传统伦理道德观念的反思性审视,开启了寻求社会现代化和新民人格的实践探索。梁启超主张伦理观念应当积极适应现代社会的发展需求,强调传统儒家伦理学和现代西方伦理学之间的文明互鉴。梁启超的新民伦理含有三个维度的伦理观念,即“国家认同类”“社会合群类”和“个人自觉类”,且三个维度的价值取向之间互补相通,形成了一个立体而有深度的伦理观念体系。这些思想智慧共同构建了一个具有包容性、平衡性和全面性的伦理体系,有助于指导个体在中国近代复杂的伦理抉择中找到契合的实践方向。梁启超关于新民伦理的思考与探索,对中国近代伦理道德的完善以及中国近代社会生活的革新产生了深远影响,对现代伦理话语的推进以及现代伦理理论的建构给予了重要启示。

关键词：梁启超新民伦理文明互鉴中国近代现代伦理

Probabilistic Response and Short-Term Extreme Load Estimation of Offshore Monopile Wind Turbine Towers by Probability Density Evolution Method

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China Ocean Engineering 2022年第3期36卷 363-371页

作者： ZHANG Hui xu ya-zhou School of Building Services Science and Engineering Xi’an University of Architecture and TechnologyXi’an 710055China School of Civil Engineering Xi’an University of Architecture and TechnologyXi’an 710055China

A new analysis framework based on probability density evolution method(PDEM)and its Chebyshev collocation solution are introduced to predict the dynamic response and short-term extreme load of offshore wind turbine(OWT)towers subjected to random sea *** regard to the stochastic responses,random function method is employed to generate samples of sea elevation,the probability density evolution equation(PDEE)is solved to calculate time-variant probability density functions of structural *** the probabilistic load estimation,a FAST model of NREL 5MW offshore turbine is established to obtain samples of bending moment at the tower *** equivalent extreme event theory is used to construct a virtual stochastic process(VSP)to assess the short-term extreme *** results indicate that the proposed approach can predict time-variant probability density functions of the structural responses,and shows good agreement with Monte Carlo ***,the predicted short-term extreme load can capture the fluctuation at the tail of the extreme value distribution,thus is more rational than results from the typical distribution ***,the proposed method shows good adaptation,precision and efficiency for the dynamic response analysis and load estimation of OWT towers.

关键词： offshore wind turbine probability density evolution method Chebyshev collocation matrix exponential Monte Carlo

徐州市与南京市三级教学医院抗菌药物使用与鲍曼不动杆菌耐亚胺培南的相关性研究

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抗感染药学 2024年第4期21卷 365-369页

作者：刘莹曹加许亚洲徐州市妇幼保健院检验科江苏徐州221009 江苏省人民医院药学部南京210029 徐州市妇幼保健院药事科江苏徐州221009

目的:分析江苏省徐州市和南京市两地三级教学医院抗菌药物使用与鲍曼不动杆菌(Acinetobacter baumannii,AB)耐亚胺培南的相关性,为临床减少亚胺培南耐药鲍曼不动杆菌(imipenem-resistantAcinetobacter baumannii,IRAB)的产生提供参考。... 详细信息

目的:分析江苏省徐州市和南京市两地三级教学医院抗菌药物使用与鲍曼不动杆菌(Acinetobacter baumannii,AB)耐亚胺培南的相关性,为临床减少亚胺培南耐药鲍曼不动杆菌(imipenem-resistantAcinetobacter baumannii,IRAB)的产生提供参考。方法:收集2019年1月-2021年12月徐州市2所三级教学医院和南京市4所三级教学医院住院患者标本中所检出的15434株鲍曼不动杆菌作为研究资料,采用相关系数法和线性回归法分析3年间南京和徐州医院抗菌药物使用与IRAB产生的相关性。结果:2019年-2021年徐州和南京两地IRAB构成比均呈明显增高趋势,而碳青霉烯类、β-内酰胺类和氟喹诺酮类药物的使用分别与IRAB的构成比呈显著相关(P<0.05)。结论:减少碳青霉烯类、哌拉西林-他唑巴坦钠、氟喹诺酮类等抗菌药物使用可能有助于降低IRAB的产生。

关键词：抗菌药物使用亚胺培南耐药鲍曼不动杆菌相关性

Broussonin E suppresses LPS-induced inflammatory response in macrophages via inhibiting MAPK pathway and enhancing JAK2-STAT3 pathway

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Chinese Journal of Natural Medicines 2019年第5期17卷 372-380页

作者： HUANG Shao-Peng GUAN Xin KAI Guo-Yin xu ya-zhou xu Yuan WANG Hao-Jie PANG Tao ZHANG Lu-Yong LIU Ying School of Basic Medicine Center for Drug Screening and Pharmacodynamics Evaluation School of Pharmacy Guangdong Pharmaceutical University College of Pharmaceutical Science Zhejiang Chinese Medical University Jiangsu Key Laboratory of Drug Screening State Key Laboratory of Natural Medicines China Pharmaceutical University School of Medicine and Life Sciences Nanjing University of Chinese Medicine

Macrophages play an important role in inflammation, and excessive and chronic activation of macrophages leads to systemic inflammatory diseases, such as atherosclerosis and rheumatoid arthritis. In this paper, we explored the anti-inflammatory effect of broussonin E, a novel phenolic compound isolated from the barks of Broussonetia kanzinoki, and its underlying molecular mechanisms. We discovered that Broussonin E could suppress the LPS-induced pro-inflammatory production in RAW264.7 cells, involving TNF-α, IL-1β, IL-6, COX-2 and iNOS. And broussonin E enhanced the expressions of anti-inflammatory mediators such as IL-10, CD206 and arginase-1(Arg-1) in LPS-stimulated RAW264.7 cells. Further, we demonstrated that broussonin E inhibited the LPS-stimulated phosphorylation of ERK and p38 MAPK. Moreover, we found that broussonin E could activate janus kinase(JAK) 2, signal transducer and activator of transcription(STAT) 3. Downregulated pro-inflammatory cytokines and upregulated anti-inflammatory factors by broussonin E were abolished by using the inhibitor of JAK2-STAT3 pathway, WP1066. Taken together, our results showed that broussonin E could suppress inflammation by modulating macrophages activation state via inhibiting the ERK and p38 MAPK and enhancing JAK2-STAT3 signaling pathway, and can be further developed as a promising drug for the treatment of inflammation-related diseases such as atherosclerosis.

关键词： Broussonin E Macrophage polarization Inflammation Janus kinase 2 Signal transducer and activator of transcription 3

Fabricating functionally graded Fe-Cr-Co permanent magnetic alloys via laser powder bed fusion

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Journal of Iron and Steel Research International 2024年第3期31卷 729-737页

作者： ya-zhou He ya-qing Hou Peng Shen Hao Zhang Dong zhou Hang Su Central Iron and Steel Research Institute Co. Ltd.Beijing 100081China Material Digital R&D Center China Iron and Steel Research Institute Group Co.Ltd.Beijing 100081China

Laser powder bed fusion(LPBF)in-situ alloying technology offers the possibility to construct gradient materials with varied structures and *** graded Fe-Cr-Co permanent magnetic alloys were fabricated by LPBF and in-situ alloying mixed powders of Fe,Cr,and Co *** effects of different Fe,Cr and Co contents on the microstructure,magnetic properties and hardness of Fe-Cr-Co alloys prepared by LPBF were *** as-built Fe-Cr-Co alloys present a single body-centered-cubic phase and have a homogeneous distribution of *** mechanical properties and magnetic properties of the compositionally graded sample show a gradient *** the increase in Cr content,the Vickers hardness of the sample increases,and the saturation magnetization of the sample *** optimal magnetic properties in an isotropic state are given as coercivity HcB=21.65 kA/m,remanence Br=0.70 T and energy product(BH)_(max)=5.35 kJ/m^(3),which are comparable to or higher than the reported magnetic properties in an isotropic state prepared by traditional powder *** in-situ alloying technology has the potential to further explore Fe-Cr-Co magnetic materials,such as those consisting of multiple or more constituent elements,and to maximize the compositional flexibility of magnetic materials.

关键词： Fe-Cr-Co alloy Laser powder bed fusion In-situ alloying Functional material Magnetic property

Nitrogen-doped titanium dioxide/schwertmannite nanocomposites as heterogeneous photo-Fenton catalysts with enhanced efficiency for the degradation of bisphenol A

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Journal of Environmental Sciences 2024年第9期143卷 1-11页

作者： Xing-Xing Qiao Yu-Hang xu Xiang-Ji Liu Sai-Le Chen zhou Zhong ya-Feng Li Jian Lü Fujian Provincial Key Laboratory of Soil Environmental Health and Regulation College of Resources and EnvironmentFujian Agriculture and Forestry UniversityFuzhou 350002China State Key Laboratory of Photocatalysis on Energy and Environment Fuzhou UniversityFuzhou 350116China

Potential health risks related to environmental endocrine disruptors(EEDs)have aroused research hotspots at the forefront of water treatment ***,nitrogen-doped titanium dioxide/schwertmannite nanocomposites(N-TiO_(2)/SCH)have been successfully developed as heterogeneous catalysts for the degradation of typical EEDs via photo-Fenton *** to the sustainable Fe(Ⅲ)/Fe(Ⅱ)conversion induced by photoelectrons,as-prepared N-TiO_(2)/SCH nanocomposites exhibit much enhanced efficiency for the degradation of bisphenol A(BPA;ca.100% within 60 min under visible irradiation)in a wide pH range of 3.0-7.8,which is significantly higher than that of the pristine schwertmannite(ca.74.5%)or N-TiO_(2)(ca.10.8%).In this photo-Fenton system,the efficient degradation of BPA is mainly attributed to the oxidation by hydroxyl radical(·OH)and singlet oxygen(^(1)O_(2)).Moreover,the possible catalytic mechanisms and reaction pathway of BPA degradation are systematically investigated based on analytical and photoelectrochemical *** work not only provides a feasible means for the development of novel heterogeneous photo-Fenton catalysts,but also lays a theoretical foundation for the potential application of mineral-based materials in wastewater treatment.

关键词： Titanium dioxide Schwertmannite Fenton reaction Environmental endocrine disruptors Photocatalysis

Two-dimensional silica enhanced solid polymer electrolyte for lithium metal batteries

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Particuology 2024年第2期85卷 146-154页

作者： Zhihong Luo Weiyong Li Chong Guo ya Song Mingxia zhou yan Shi Jing xu Long Li Bin Shi Quansheng Ouyang Jiao-jing Shao Guangmin zhou School of Materials and Metallurgy Guizhou UniversityGuiyang550025China State Key Laboratory of Advanced Chemical Power Sources Zunyi563003China Graphene Materials Engineering Research Center of Guizhou Colleges and Universities Guiyang550025China Tsinghua-Berkeley Shenzhen Institute&Tsinghua Shenzhen International Graduate Schoo Tsinghua UniversityShenzhen518055China

Solid polymer electrolytes(SPEs)are promising substitutes for current flammable liquid electrolytes to achieve high-safety and high-energy-density lithium metal *** oxide(PEO)based solid polymer electrolytes have attracted increasing attention because of their excellent flexibility,manufacturability,light weight,and low-cost processing,while they often suffer from low ionic con-ductivity at room temperature,low lithium transference number and unsatisfactory interfacial resis-tance,which largely restrain their practical ***,two-dimensional holey silica nanosheets(2D-HSN)as the fillers,together with LiNO_(3) as the electrolyte additive,are introduced in a PEO/poly(-vinylidene fiuoride-co-hexafluoropropylene)(PVDF-HFP)blended polymer matrix to obtain a *** incorporation of HSN filler creates supplementary channels for lithium ion migration and lowers the crystallinity of the polymer,thereby facilitating the movement of lithium *** HSN-based SPE demonstrates higher ionic conductivity up to 3.7 x 10-4 S cm-1 at 30℃,larger Li+transference number close to 0.34,and more stable lithium plating/stripping than that without the fillers,and HSN can promote the formation of more stable solid electrolyte interphase(SEI)*** as-assembled LiFePO4||Li batteries deliver a high specific capacity of 159 mA h g-1 with the capacity retention of 95.5%after 200 cycles at 30℃,as well as superior rate performance and cycling stability compared to that using the blank SPE.

关键词： Vermiculite nanosheets Two-dimensional silica Solid polymer electrolytes FillersLithium metal batteries

The RFI Fast Mitigation Algorithm Based on Block LMS Filter

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Research in Astronomy and Astrophysics 2024年第1期24卷 265-272页

作者： Han Wu Hai-Long Zhang ya-zhou Zhang Jie Wang xu Du Ting Zhang Xin-Chen Ye Xinjiang Astronomical Observatory Chinese Academy of SciencesUrumqi 830011China University of Chinese Academy of Sciences Beijing 100049China Key Laboratory of Radio Astronomy Chinese Academy of SciencesNanjing 210008China National Astronomical Data Center Beijing 100101China

The radio telescope possesses high sensitivity and strong signal collection *** receiving celestial radiation signals,it also captures Radio Frequency Interferences(RFIs)introduced by human ***,as signals originating from sources other than the astronomical targets,significantly impacts the quality of astronomical *** paper presents an RFI fast mitigation algorithm based on block Least Mean Square(LMS)*** enhances the traditional adaptive LMS filter by grouping L adjacent time-sampled points into one block and applying the same filter coefficients for filtering within each *** transformation reduces multiplication calculations and enhances algorithm efficiency by leveraging the time-domain convolution *** algorithm is tested using baseband data from the Parkes 64 m radio telescope's pulsar observations and simulated *** results confirm the algorithm's effectiveness,as the pulsar profile after RFI mitigation closely matches the original pulsar profile.

关键词： methods:data analysis techniques:interferometric (stars:)pulsars:individual(J0437-4715)

Erythrodermic mycosis fungoides: A case report

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World Journal of Clinical Cases 2024年第1期12卷 130-135页

作者： Wu-Bing xu ya-Ping Zhang Su-Ping zhou Hao-yang Bai Department of Radiology Shaoxing People’s HospitalKey Laboratory of Functional Molecular Imaging of Tumor and Interventional Diagnosis and Treatment of Shaoxing CityShaoxing 312000Zhejiang ProvinceChina

BACKGROUND Mycosis fungoides is the most common primary cutaneous T-cell lymphoma,whereas generalized erythroderma is *** this report,we describe a case of mycosis fungoides with generalized erythroderma using complete clinical data and[18F]fluoroDglucose positron emission tomography/computed tomography(18F-FDG PET/CT)*** SUMMARY Systemic skin redness with desquamation for three years confirmed mycosis fungoides within one *** patient underwent left axillary lymphadenectomy biopsy;pathological biopsy suggested abnormal T-cell lesions consistent with mycosis fungoides involving lymph *** patient received methotrexate,5 mg twice weekly,as part of their chemotherapy *** January half after discharge,no obvious cause of high fever,left axillary lymph nodes with red heat pain,and rupture entered our hospital for *** The 18F-FDG PET/CT is essential for early diagnosis and timely treatment.

关键词： Mycosis fungoides Positron emission tomography/computed tomography Imaging Diagnosis Differential diagnosis Treatment Case report