检索结果-南通市图书馆

Science China(Technological Sciences) 2021年第5期64卷 957-970页

作者： xu xiaohu YE SongTao YANG ZeYuan YAN SiJie ZHU DaHu DING Han State Key Laboratory of Digital Manufacturing Equipment and Technology Huazhong University of Science and TechnologyWuhan 430074China Hubei Key Laboratory of Advanced Technology for Automotive Components Wuhan University of TechnologyWuhan 430070China Hubei Collaborative Innovation Center for Automotive Components Technology Wuhan University of TechnologyWuhan 430070China

Precision prediction of machined surface roughness is challenging facing the robotic belt grinding of complex blade,since this process is accompanied by significant elastic deformation.The resulting poor prediction accuracy,to a great extent,is attributed to the existing prediction model which less considers the dynamics.In this paper,an improved scallop height model is developed to predict and assess the machined surface roughness by taking into account the elastic deformation and the varying curvature of blade,then robotic belt grinding experiments are carried out to evaluate the proposed model from the perspective of surface roughness.Finally factors that influence the scallop height are analyzed,and the suitable empirical equation of surface roughness is proposed to assess and predict the surface quality from the aspect of blade concave and convex surface by adopting the constant scallop height machining.

关键词： robotic belt grinding scallop height elastic deformation surface roughness prediction

NONLINEAR MOTION MECHANICS MODEL OF CURVED BLOOD VESSEL

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Acta Mechanica Solida Sinica 2003年第1期16卷 67-73页

作者： Qiao Aike Liu Youjun Wu Shigui xu xiaohu Zeng Yanjun Medical School Shantou UniversityShantou 515031China College of Mechanical Engineering Beijing University of TechnologyBeijing 100022China

A geometric model of curved blood vessels is established based on some reasonable hypotheses; the nonlinear motion mechanics model of the curved blood vessel is established according to basic mechanics laws. This model includes much more physiological factors. It couples the interaction of blood flow with mechanical factors such as the displacement, deformation, strain and stress etc. of the curved blood vessel. It is of great importance for investigating the circulation rules of the cardiovascular system and the nonlinear pulse wave propagation in curved blood vessels.

关键词： curved blood vessel motion equation mechanics model pulse wave propagation

Biohythane production from two-stage anaerobic digestion of food waste:A review

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Journal of Environmental Sciences 2024年第5期139卷 334-349页

作者： Xiaona An Ying xu xiaohu Dai State Key Laboratory of Pollution Control and Resource Reuse School of Environmental Science and EngineeringTongji UniversityShanghai 200092China Shanghai Institute of Pollution Control and Ecological Security Shanghai 200092China

The biotransformation of food waste(FW)to bioenergy has attracted considerable research attention as a means to address the energy crisis and waste disposal problems.To this end,a promising technique is two-stage anaerobic digestion(TSAD),in which the FW is transformed to biohythane,a gaseous mixture of biomethane and biohydrogen.This review summarises the main characteristics of FW and describes the basic principle of TSAD.Moreover,the factors influencing the TSAD performance are identified,and an overview of the research status;economic aspects;and strategies such as pre-treatment,co-digestion,and regulation of microbial consortia to increase the biohythane yield from TSAD is provided.Additionally,the challenges and future considerations associated with the treatment of FW by TSAD are highlighted.This paper can provide valuable reference for the improvement and widespread implementation of TSAD-based FW treatment.

关键词： Two-stage anaerobic digestion(TSAD) Food waste(FW) Methane production Hydrogen production

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相思子中毒致急性脑干损伤1例

中国工业医学杂志 2024年第1期37卷 62-63,82页

作者：邹心瑞许啸虎华中科技大学同济医学院附属同济医院第二临床学院湖北武汉430016 华中科技大学同济医学院附属同济医院中西医结合科

相思子中毒致急性脑干损伤的病例较为罕见。本文报道1例相思子中毒致急性脑干损伤患者的临床资料,虽经药物、血液灌流、连续肾脏替代及呼吸机辅助通气等治疗,患者预后不佳。提示早期诊断、治疗是相思子中毒救治成功的关键。

关键词：相思子中毒急性脑干损伤

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绝对式圆时栅偏心状态自诊断测量方法研究

重庆理工大学学报（自然科学） 2024年第1期38卷 248-254页

作者：陈磊于治成许小虎樊星辰李佳豪重庆理工大学机械检测与装备技术教育部工程研究中心重庆400054 时栅传感及先进检测技术重庆市重点实验室重庆400054 合肥工业大学仪器科学与光电工程学院合肥230009 中国通用技术集团国测时栅科技有限公司重庆400039

针对圆时栅传感器在安装过程中因定子和转子不同心而在整周测量结果中的较大1次谐波误差,影响传感器测量精度的问题,提出了一种基于多测头结构的绝对式圆时栅偏心状态自诊断测量方法。采用多测头结构在圆时栅转子的内外圈分别布置单个和... 详细信息

针对圆时栅传感器在安装过程中因定子和转子不同心而在整周测量结果中的较大1次谐波误差,影响传感器测量精度的问题,提出了一种基于多测头结构的绝对式圆时栅偏心状态自诊断测量方法。采用多测头结构在圆时栅转子的内外圈分别布置单个和4个独立的感应测头,根据内外圈感应信号的比相关系,判断传感器安装偏心程度,实现传感器在偏心状态下的自诊断功能。通过LabVIEW搭建的测量系统,能同时处理内圈单路感应信号和外圈4路感应信号的相位计数值,得到传感器的绝对位置信息并显示绝对角位移值。实验结果表明,传感器样机经过诊断指示调整安装后,整周测量误差精度可达±1″,有效提高了传感器的测量精度。

关键词：多测头圆时栅安装偏心自诊断

交泰丸治疗多囊卵巢综合征伴焦虑抑郁临床研究

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中西医结合研究 2024年第1期16卷 6-10页

作者：彭宏偲王宏展王志吴笑许啸虎蕲春县人民医院临床营养科湖北黄冈435300 华中科技大学同济医学院附属同济医院中西医结合科武汉430030

目的探讨交泰丸治疗多囊卵巢综合征(polycystic ovary syndrome,PCOS)伴焦虑抑郁的临床疗效。方法选取60例PCOS伴焦虑抑郁患者,将其随机分为对照组与治疗组,每组30例。对照组给予二甲双胍片口服治疗,治疗组在对照组基础上加服交泰丸中... 详细信息

目的探讨交泰丸治疗多囊卵巢综合征(polycystic ovary syndrome,PCOS)伴焦虑抑郁的临床疗效。方法选取60例PCOS伴焦虑抑郁患者,将其随机分为对照组与治疗组,每组30例。对照组给予二甲双胍片口服治疗,治疗组在对照组基础上加服交泰丸中药颗粒,2组均连续干预12周。比较2组治疗前后糖脂代谢、性激素、神经递质等指标以及焦虑、抑郁和睡眠评分等的变化。结果治疗后,2组空腹血糖(fasting blood glucose,FBG)、空腹胰岛素(fasting insulin,FINS)、总胆固醇(total cholesterol,TC)和甘油三酯(triglyceride,TG)等指标水平均较治疗前降低(P均<0.05),且治疗组TG和FINS明显低于对照组(P均<0.05)。2组黄体生成素(luteinizing hormone,LH)、睾酮(testosterone,T)和LH/FSH比值均较治疗前降低(P均<0.05),且治疗组T和LH/FSH降低更明显(P均<0.05)。对照组焦虑自评量表(self-rating anxiety scale,SAS)评分较治疗前降低(P<0.05),而治疗组SAS、抑郁自评量表(self-rating depression scale,SDS)评分和匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)评分均较治疗前降低(P均<0.05),组间比较,治疗组降低更明显(P均<0.05)。对照组γ-氨基丁酸(γ-aminobutyric acid,GABA)较治疗前降低(P<0.05),而治疗组5-羟色胺(5-hydroxytryptamine,5-HT)和GABA均较治疗前降低(P均<0.05);与对照组比较,治疗组降低更明显(P均<0.05)。结论交泰丸和二甲双胍均能明显改善PCOS患者糖脂代谢和性激素水平;与单用二甲双胍相比,交泰丸联合二甲双胍改善TG、FINS、T和LH/FSH的效果更明显,且能明显改善患者的焦虑、抑郁评分和睡眠质量,其机制可能与调节神经递质GABA和5-HT的分泌有关。

关键词：多囊卵巢综合征交泰丸焦虑抑郁糖脂代谢神经递质

弥漫大B细胞淋巴瘤患者继发中枢神经系统侵犯风险评估和预防策略的研究现状

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国际输血及血液学杂志 2024年第1期47卷 23-30页

作者：徐小虎姚一茗史玉叶王春玲南京医科大学附属淮安第一医院血液科淮安223300

弥漫大B细胞淋巴瘤(DLBCL)继发中枢神经系统(CNS)侵犯是一种少见但后果严重的临床事件,该类患者预后差,早期识别及预防尤为重要。CNS-国际预后指数(IPI)是评估DLBCL继发CNS侵犯风险的常用模型,但其敏感度及特异度均不够理想。目前研究... 详细信息

弥漫大B细胞淋巴瘤(DLBCL)继发中枢神经系统(CNS)侵犯是一种少见但后果严重的临床事件,该类患者预后差,早期识别及预防尤为重要。CNS-国际预后指数(IPI)是评估DLBCL继发CNS侵犯风险的常用模型,但其敏感度及特异度均不够理想。目前研究者正尝试将分子生物学因素与CNS-IPI结合,旨在更好地识别高危患者,从而指导预防其CNS侵犯。鞘内注射(IT)和全身应用甲氨蝶呤(MTX)是该病的标准预防策略,二者疗效接近,但各有利弊。来那度胺、伊布替尼等新疗法也被证实能有效防治原发性和继发性CNS淋巴瘤(CNSL),这值得进一步探索。笔者拟就DLBCL患者继发CNS侵犯风险评估和预防策略的研究现状进行阐述,旨在为临床医师诊治该病提供参考。

关键词：淋巴瘤,大B细胞,弥漫性中枢神经系统肿瘤肿瘤转移风险评估二级预防

免疫调节机制在免疫性血小板减少症中的研究进展

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检验医学与临床 2024年第9期21卷 1332-1335,1340页

作者：徐小凡李一鸣徐小虎代义龙(综述) 金呈强(审校) 济宁医学院临床学院山东济宁272000 济宁医学院附属医院检验科山东济宁272007

免疫性血小板减少症(ITP)是一种罕见血液学疾病,属于获得性自身免疫性疾病。免疫紊乱是其最主要原因,其发病机制越来越受大家关注。目前研究显示自身抗血小板抗体的产生、Th1细胞/Th2细胞及Th17细胞/调节性T(Treg)细胞比例失衡、细胞毒... 详细信息

免疫性血小板减少症(ITP)是一种罕见血液学疾病,属于获得性自身免疫性疾病。免疫紊乱是其最主要原因,其发病机制越来越受大家关注。目前研究显示自身抗血小板抗体的产生、Th1细胞/Th2细胞及Th17细胞/调节性T(Treg)细胞比例失衡、细胞毒性T淋巴细胞高增殖及低凋亡、调节性B淋巴细胞数量减少及功能障碍、细胞凋亡、遗传及细胞自噬等在ITP的发病机制中发挥关键作用,该文从以上6个方面综述了近年发现的参与ITP发病的各种复杂机制,以期更全面地了解影响ITP发生发展的因素,旨在为ITP的治疗提供新的思路和靶点。

关键词：免疫性血小板减少症自身抗体细胞自噬血小板免疫

维普期刊数据库博看期刊

Influence factors of methane hydrate formation from ice:Temperature,pressure and SDS surfactant

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Chinese Journal of Chemical Engineering 2019年第2期27卷 405-410页

作者： Weiguo Liu Yanghui Li xiaohu xu Key Laboratory of Ocean Energy Utilization and Energy Conservation of Ministry of Education Dalian University of Technology

A series of experiments of forming hydrate from ice powders in different conditions have been carried out with constant volume method to evaluate the influence factors such as pressure, temperature, and SDS surfactant. The change of temperature and pressure were collected as a function of elapsed time, which were used to calculate the gas consumption and hydrate saturation during hydrate formation(pVT method). Based on the experimental results and the analysis, it is concluded that:(1) Both initial pressure and temperature have effect on the hydrate formation and temperature plays a more important role in the process;(2) heating and secondary pressurization will promote the gas hydrate formation and enhance the hydrate saturation as a result. Meanwhile, the promotion of heating seems to be more obvious than that of secondary pressurization;(3) different concentrations of SDS surfactant have clearly influence on the saturation of gas hydrate and there is an optimal concentration to promote the hydrate formation.

关键词： Methane hydrate Ice Heating Secondary pressurization Surfactant

Application of novel force control strategies to enhance robotic abrasive belt grinding quality of aero-engine blades

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Chinese Journal of Aeronautics 2019年第10期32卷 2368-2382页

作者： xiaohu xu Dahu ZHU Haiyang ZHANG Sijie YAN Han DING State Key Laboratory of Digital Manufacturing Equipment and Technology Huazhong University of Science and TechnologyWuhan 430074China Hubei Key Laboratory of Advanced Technology for Automotive Components Wuhan University of TechnologyWuhan 430070China Hubei Collaborative Innovation Center for Automotive Components Technology Wuhan University of TechnologyWuhan 430074China Wuxi CRRC Times Intelligent Equipment Co. Ltd.Wuxi 214174China

Robotic belt grinding has emerged as a finishing process in recent years for machining components with high surface finish and flexibility.The surface machining consistency,however,is difficult to be guaranteed in such a process.To overcome this problem,a method of hybrid force-position control combined with PI/PD control is proposed to be applied in robotic abrasive belt grinding of complex geometries.Voltage signals are firstly obtained and transformed to force information with signal conditioning methods.Secondly,zero drift and gravity compensation algorithms are presented to calibrate the F/T transducer which is installed on the robot end-effector.Next,a force control strategy combining hybrid force-position control with PI/PD control is introduced to be employed in robotic abrasive belt grinding operations where the force control law is applied to the Z direction of the tool frame and the positon control law is used in the X direction of the tool frame.Then,the accuracy of the F/T transducer and the robotic force control system is analyzed to ensure the stability and reliability of force control in the robotic grinding process.Finally,two typical cases on robotic belt grinding of a test workpiece and an aero-engine blade are conducted to validate the practicality and effectiveness of the force control technology proposed.

关键词： Gravity compensation Hybrid force-position control PI/PD control Robotic belt grinding Zero drift compensation