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Spatiotemporal variations in glacier area and surface velocity of the northern Antarctic Peninsula during 2018-2022

Advances in Climate Change Research 2024年第2期15卷 297-311页

作者： Yu-Long KANG Shi-Chang KANG Wan-Qin GUO Tao CHE Zong-Li JIANG Zhen-Feng WANG qiang-qiang xu Cheng-De YANG State Key Laboratory of Cryospheric Science Northwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou 730000China University of Chinese Academy of Sciences Beijing 100083China Key Laboratory of Remote Sensing of Gansu Province Northwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou 730000China School of Earth Sciences and Spatial Information Engineering Hunan University of Science and TechnologyXiangtan 411201China

Ice sheet serves as a crucial indicator for assessing climate *** loss in recent remote sensing-based studies indicated that the Antarctic Peninsula has rapid rates of glacier retreat and speed up of surface ***,observations of seasonal variability of ice speed are limited,and glacier-area changes require multi-temporal *** study investigated the changes in area and surface velocities of∼375 glaciers on the northern Antarctic Peninsula(NAP)utilizing satellite images acquired by the Sentinel 1&2 satellites during *** results indicate that the glacier area reduced by approximately 166.1±44.2 km^(2)(-0.2%±0.1%per year)during the study period,with an acceleration after 2020(-0.4%±0.3%per year),and the most dramatic reduction happened on the eastern *** maximum annual ice speeds on the NAP generally exceeded 3500 m per year,while the ice speeds in 2021 were the highest(exceeded 4210 m per year).The ice speed variability in austral autumn was higher than in other seasons,meanwhile the summer ice speeds showed an increasing *** glacier G012158E47018N,McNeile Glacier,glacier G299637E64094S and Drygalski Glacier showed the most remarkable ice speed variations represented by high daily velocities and strong fluctuations on their *** results demonstrated that the variations in glacier area and seasonal ice speed on the NAP were responsive to the ice-ocean-atmosphere ***,seasonal velocity and area variations should be considered when conducting accurate mass balance calculations,model validations and change mechanism analyses under climate warming scenarios.

关键词： Glacier area Seasonal ice speed Sentinel 1&2 Northern Antarctic Peninsula Ice-ocean-atmosphere processes

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Targeting oxidative stress with natural products: A novel strategy for esophageal cancer therapy

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World Journal of Gastrointestinal Oncology 2024年第2期16卷 287-299页

作者： Fang Cao Han-Ling Zhang Cui Guo xue-Liang xu qiang Yuan Department of Rehabilitation III Hospital of Chengdu University of Traditional Chinese MedicineChengdu 610072Sichuan ProvinceChina Department of Rehabilitation Chongqing Fuling District Maternal and Child Health HospitalChongqing 408000China Department of Rehabilitation Hospital of Chengdu University of Traditional Chinese MedicineChengdu 610072Sichuan ProvinceChina

Esophageal cancer(ESC)is a malignant tumor that originates from the mucosal epithelium of the esophagus and is part of the digestive *** the exact pathogenesis of ESC has not been fully elucidated,excessive oxidative stress is an important characteristic that leads to the development of many *** expression of several proteins and transcription factors contributes to oxidative stress in ESCs,which alters the growth and proliferation of ESCs and promotes their *** compounds,including alkaloids,terpenes,polyphenols,and xanthine compounds,can inhibit reactive oxygen species production in *** compounds reduce oxidative stress levels and subsequently inhibit the oc-currence and progression of ESC through the regulation of targets and pathways such as the cytokine interleukins 6 and 10,superoxide dismutase,the NF-+ACY-kappa+ADs-B/MAPK pathway,and the mammalian Nrf2/ARE target ***,targeting tumor oxidative stress has become a key focus in anti-ESC *** review discusses the potential of Natural products(NPs)for treating ESCs and summarizes the application prospects of oxidative stress as a new target for ESC *** findings of this review provide a reference for drug development targeting ***,further high-quality studies will be necessary to determine the clinical efficacy of these various NPs.

关键词： Oxidative stress Natural products Esophageal cancer Reactive oxygen species

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MiRNA-145-5p inhibits gastric cancer progression via the serpin family E member 1-extracellular signal-regulated kinase-1/2 axis

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World Journal of Gastrointestinal Oncology 2024年第5期16卷 2123-2140页

作者： Hong-Xia Bai xue-Mei Qiu Chun-Hong xu Jian-qiang Guo Department of Gastroenterology The Second Hospital of Shandong UniversityJinan 250000Shandong ProvinceChina Department of Gastroenterology Liaocheng People’s HospitalLiaocheng 252000Shandong ProvinceChina Department of Reproductive Center Zaozhuang Maternal and Child Health Care HospitalZaozhuang 277000Shandong ProvinceChina

BACKGROUND MicroRNAs(miRNAs)regulate gene expression and play a critical role in cancer ***,there is still a limited understanding of the function and regulatory mechanism of miRNAs in gastric cancer(GC).AIM To investigate the role and molecular mechanism of miRNA-145-5p(miR145-5p)in the progression of *** Real-time polymerase chain reaction(RT-PCR)was used to detect miRNA expression in human GC tissues and *** ability of cancer cells to migrate and invade was assessed using wound-healing and transwell assays,*** proliferation was measured using cell counting kit-8 and colony formation assays,and apoptosis was evaluated using flow *** of the epithelial-mesenchymal transition(EMT)-associated protein was determined by Western *** of miR-145-5p were predicated using bioinformatics analysis and verified using a dual-luciferase reporter *** family E member 1(SERPINE1)expression in GC tissues and cells was evaluated using RT-PCR and immunohistochemical *** correlation between SERPINE1 expression and overall patient survival was determined using Kaplan-Meier plot *** association between SERPINE1 and GC progression was also tested.A rescue experiment of SERPINE1 overexpression was conducted to verify the relationship between this protein and *** mechanism by which miR-145-5p influences GC progression was further explored by assessing tumor formation in nude *** GC tissues and cells had reduced miR-145-5p expression and SERPINE1 was identified as a direct target of this *** of miR-145-5p was associated with decreased GC cell proliferation,invasion,migration,and EMT,and these effects were reversed by forcing SERPINE1 ***-Meier plot analysis revealed that patients with higher SERPINE1 expression had a shorter survival rate than those with lower SERPINE1 *** mouse tumorigenesis experiments confirmed that miR-145-5p target

关键词： Gastric cancer MicroRNA-145-5p Serpin family E member 1 Epithelial-mesenchymal transition Proliferation Extracellular signal-regulated kinase-1/2

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Data-driven mapping-relationship mining between hardness and mechanical properties of dual-phase titanium alloys via random forest and statistical analysis

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Rare Metals 2024年第2期43卷 829-841页

作者： Hai-Chao Gong Qun-Bo Fan Hong-Mei Zhang Xing-Wang Cheng Wen-qiang Xie Kai Chen Lin Yang Jun-Jie Zhang Bing-qiang Wei shun xu School of Materials Science and Engineering Beijing Institute of TechnologyBeijing100081China National Key Laboratory of Science and Technology on Materials Under Shock and Impact Beijing100081China Beijing Institute of Technology Chongqing Innovation Center Chongqing401135China Department of Mechanical and Materials Engineering University of Nebraska-LincolnLincolnNE68588USA

In order to accelerate the research on the property optimization of titanium alloy based on high-throughput methods,it is necessary to reveal the relationship between hardness and other mechanical properties which is still *** this work,taking Ti20C alloy as research object,almost all the microstructure of dual-phase titanium alloys were covered by traversing over 100 heat treatment ***,massive experiments including microstructure characterization and performance test were conducted,obtaining 51,590 pieces of microstructure data and 3591 pieces of mechanical property ***,based on large-scale data-driven technology,the quantitative mapping relationship between hardness and other mechanical properties was deeply *** results of random forest models showed that the correlation between hardness(H)and Charpy impact energy(A_(k))(or elongation,A)was hardly dependent on the microstructure types,while the relationship between H and tensile strength(R_(m))(or yield strength,R_(p0.2))was highly dependent on microstructure ***,combined with statistical analysis,it was found that the relationship between H and Ak(or A)were negatively ***,the relationship between H and strength was positively linear for equiaxed microstructure,and strength was linked to d^(−1/2)(d,equivalent circle diameter)ofα-grains in the form of classical Hall–Petch formula;but for other microstructures,the relationships were ***,the above rules were nearly the same in the rolling direction and transverse ***,a"four-quadrant partition map"between H and R_(p0.2)/R_(m) was established as a versatile material-screening tool,which can provide guidance for on-demand selection of titanium alloys.

关键词： Dual-phase titanium alloy Data-driven Hardness Mapping relationship

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Robotic vs laparoscopic abdominoperineal resection for rectal cancer:A propensity score matching cohort study and metaanalysis

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World Journal of Gastrointestinal Surgery 2024年第5期16卷 1280-1290页

作者： Li Song Wen-Qiong xu Zheng-qiang Wei Gang Tang Department of Gastrointestinal Surgery Chengdu Fifth People's HospitalChengdu 610000Sichuan ProvinceChina Department of Nephrology Chengdu Fifth People's HospitalChengdu 610000Sichuan ProvinceChina Department of Gastrointestinal Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400000China Division of Biliary Tract Surgery Department of General SurgeryWest China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina

BACKGROUND Robotic surgery(RS)is gaining popularity;however,evidence for abdominoperineal resection(APR)of rectal cancer(RC)is *** To compare the efficacy of RS and laparoscopic surgery(LS)in APR for *** We retrospectively identified patients with RC who underwent APR by RS or LS from April 2016 to June *** regarding short-term surgical outcomes were compared between the two *** reduce the effect of potential confounding factors,propensity score matching was used,with a 1:1 ratio between the RS and LS groups.A meta-analysis of seven trials was performed to compare the efficacy of robotic and laparoscopic APR for RC *** Of 133 patients,after propensity score matching,there were 42 patients in each *** postoperative complication rate was significantly lower in the RS group(17/42,40.5%)than in the LS group(27/42,64.3%)(P=0.029).There wasno significant difference in operative time(P=0.564),intraoperative transfusion(P=0.314),reoperation rate(P=0.314),lymph nodes harvested(P=0.309),or circumferential resection margin(CRM)positive rate(P=0.314)between the two *** meta-analysis showed patients in the RS group had fewer positive CRMs(P=0.04),lesser estimated blood loss(P<0.00001),shorter postoperative hospital stays(P=0.02),and fewer postoperative complications(P=0.002)than patients in the LS *** Our study shows that RS is a safe and effective approach for APR in RC and offers better short-term outcomes than LS.

关键词： Robotic surgery Laparoscopic surgery Abdominoperineal resection Postoperative complications Propensity score

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Harmful evaluation of heavy metals from soil layer to the groundwater: Take the Jilin Hunchun Basin as an example

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China Geology 2024年第1期7卷 116-124页

作者： Xiao-Dong Guo qiang Liu Hui-Rong Zhang xu-Fei Shi Chuan-Yu Qin Zhi-qiang Zhang Shenyang Geological Survey Center China Geological SurveyMinistry of Natural ResourcesShenyang 110034China Key Laboratory of Black Land Evolution and Ecological Effects Shenyang 110034China New Energy and Environment College Jilin UniversityChangchun 130026China Jilin Hydrogeological Survey Institute Changchun 130026China

The continuous enrichment of heavy metals in soils has caused potential harm to *** methods to evaluate the harm of heavy metals in soil to groundwater are lacked in previous *** on the theory of groundwater circulation and solid-liquid equilibrium,a simple and easy-touse flux model of soil heavy metals migrating to groundwater is *** on groundwater environmental capacity,an innovative method for evaluating the harm of heavy metals in soil to groundwater is proposed,which has been applied in Hunchun Basin,Jilin Province,*** results show that the fluxes of soil heavy metals into groundwater in the study area are Zn,Cu,As,Pb,Cd,Ni,and Hg in descending *** content of heavy metals in groundwater(As,Hg,Cu,Pb,Zn,Ni,and Cd)in most areas has not risen to the threshold of environmental capacity within 10 *** harm levels of soil heavy metals to groundwater in the most townships soils are at the moderate level or *** evaluation method can quantify the flux of soil heavy metals into groundwater simply and quickly,determine the residual capacity of groundwater to heavy metals,evaluate the harm level of soil heavy metals to groundwater,provide support for relevant departments to carry out environmental protection of soil and groundwater,and provide a reference to carry out similar studies for related scholars.

关键词： Soil heavy metals As+Hg+Cu+Pb+Zn+Ni+Cd Environmental capacity Groundwater Hazard degree Migration flux model Agricultural geological survey engineering Hunchun Basin Jilin Province

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Exploring deep learning for landslide mapping:A comprehensive review

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China Geology 2024年第2期7卷 330-350页

作者： Zhi-qiang Yang Wen-wen Qi Chong xu Xiao-yi Shao College of Surveying and Geo-Informatics Tongji UniversityShanghai 200092China National Institute of Natural Hazards Ministry of Emergency ManagementBeijing 100085China Key Laboratory of Compound and Chained Natural Hazards Dynamics Ministry of Emergency Management of ChinaBeijing 100085China

A detailed and accurate inventory map of landslides is crucial for quantitative hazard assessment and land *** methods relying on change detection and object-oriented approaches have been criticized for their dependence on expert knowledge and subjective *** advancements in highresolution satellite imagery,coupled with the rapid development of artificial intelligence,particularly datadriven deep learning algorithms(DL)such as convolutional neural networks(CNN),have provided rich feature indicators for landslide mapping,overcoming previous *** this review paper,77representative DL-based landslide detection methods applied in various environments over the past seven years were *** study analyzed the structures of different DL networks,discussed five main application scenarios,and assessed both the advancements and limitations of DL in geological hazard *** results indicated that the increasing number of articles per year reflects growing interest in landslide mapping by artificial intelligence,with U-Net-based structures gaining prominence due to their flexibility in feature extraction and ***,we explored the hindrances of DL in landslide hazard research based on the above research *** such as black-box operations and sample dependence persist,warranting further theoretical research and future application of DL in landslide detection.

关键词： Landslide Mapping Quantitative hazard assessment Deep learning Artificial intelligence Neural network Big data Geological hazard survery engineering

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Improvement of impact properties of Al-Si-Mg alloy via solution treatment and joint modification with Sr and La

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Rare Metals 2024年第7期43卷 3301-3313页

作者： Xiong-Ling Zheng Shao-Xiang Li Jia-Le Ma Qing-Yan xu Hai-Dong Zhao Zhi-qiang Han Key Laboratory for Advanced Materials Processing Technology Ministry of EducationSchool of Materials Science and EngineeringTsinghua UniversityBeijing 100084China National Engineering Research Center of Near-Net Shape Forming for Metallic Materials South China University of TechnologyGuangzhou 510641China

An effort to obtain superior impact properties for Al-7Si-0.35 Mg alloy is presented,where modification with 0.02 wt% Sr and 0.1 wt% La as well as solution treatment was jointly *** samples were solution treated at 535℃ for 15 min to 12 *** microstructure,fracture mechanism,and their correlation with the impact properties of the alloy were studied in detail mainly through optical microscopy(OM),scanning electron microscopy(SEM) and oscillography impact *** results show that the addition of Sr and La refined the eutectic Si particles significantly from~ 2.05 μm(modified with Sr alone) to~ 0.75 μm in as-cast microstructure,leading to a very homogeneous distribution of spheroidized Si particles in the alloy solution treated at 535℃ for 8 *** alloy exhibits excellent impact toughness up to 75 J·cm^(-2),which is much higher than the maximum impact toughness of the alloys modified by Sr alone(~ 46 J·cm^(-2)).The major reason for this remarkable increase in the impact property is the dramatic increase in crack initiation *** dispersoid-free zones(DFZs)near the eutectic regions mainly consist of the ductile Al-matrix,which exhibits excellent *** ductile Al-matrix of the DFZs hinders the crack propagation,resulting in a significant increase in crack propagation energy.

关键词： Aluminum alloys Modification Solution treatment Microstructure Impact properties Fracture mechanism

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Inhibition of Defect-Induced Ice Nucleation, Propagation, and Adhesion by Bioinspired Self-Healing Anti-Icing Coatings

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Research 2024年第1期2023卷 237-246页

作者： shu Tian Ruiqi Li Xinmeng Liu Jiancheng Wang Junyu Yu Sijia xu Yunqing Tian Jing Yang Lei Zhang Department of Biochemical Engineering Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering(MOE)School of Chemical Engineering and TechnologyTianjin UniversityTianjin 300350China Binzhou Institute of Technology Weiqiao-UCAS Science and Technology ParkBinzhou CityShandong Province 256606China

Anti-icing coatings on outdoor infrastructures inevitably suffer from mechanical injuries in numerous icing scenarios such as hailstorms,sandstorms,impacts of foreign objects,and icing–deicing ***,the mechanisms of surface-defect-induced icing are *** the defects,water molecules exhibit stronger adsorption and the heat transfer rate increases,accelerating the condensation of water vapor as well as ice nucleation and ***,the ice–defect interlocking structure increases the ice adhesion ***,a self-healing(at−20℃)antifreeze-protein(AFP)-inspired anti-icing coating is *** coating is based on a design that mimics the ice-binding and non-ice-binding sites in *** enables the coating to markedly inhibit ice nucleation(nucleation temperature<−29.4℃),prevent ice propagation(propagation rate<0.00048 cm^(2)/s),and reduce ice adhesion on the surface(adhesion strength<38.9 kPa).More importantly,the coating can also autonomously self-heal at−20℃,as a result of multiple dynamic bonds in its structure,to inhibit defect-induced icing *** healed coating sustains high anti-icing and deicing performance even under various extreme *** work reveals the in-depth mechanism of defect-induced ice formation as well as adhesion,and proposes a self-healing anti-icing coating for outdoor infrastructures.

关键词： coating defect clarified

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Regulating zinc ion transport behavior and solvated structure towards stable aqueous Zn metal batteries

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Journal of Energy Chemistry 2024年第6期93卷 609-626,I0015页

作者： qiang Ma Aoen Ma Shanguang Lv Bowen Qin Yali xu Xianxiang Zeng Wei Ling Yuan Liu Xiongwei Wu College of Materials Engineering Henan International Joint Laboratory of Rare Earth Composite MaterialsHenan University of EngineeringZhengzhou 451191HenanChina Nanozyme Medical Center School of Basic Medical SciencesZhengzhou UniversityZhengzhou 450001HenanChina School of Chemistry and Materials Science Hunan Agricultural UniversityChangsha 410125HunanChina College of Electrical and Information Engineering Hunan UniversityChangsha 410082HunanChina Hunan Province Yin Feng New Energy Co.Ltd. Changsha 410019HunanChina

Aqueous Zn metal batteries(AZMBs)with intrinsic safety,high energy density and low cost have been regarded as promising electrochemical energy storage ***,the parasitic reaction on metallic Zn anode and the incompatibility between electrode and electrolytes lead to the deterioration of electrochemical performance of AZMBs during the *** critical point to achieve the stable cycling of AZMBs is to properly regulate the zinc ion solvated structure and transfer behavior between metallic Zn anode and *** recent years,numerous achievements have been made to resolve the formation of Zn dendrite and interface incompatible issues faced by AZMBs via optimizing the sheath structure and transport capability of zinc ions at electrode-electrolyte *** this review,the challenges for metallic Zn anode and electrode-electrolyte interface in AZMBs including dendrite formation and interface characteristics are *** the influences of different strategies involving designing advanced electrode structu re,artificial solid electrolyte interphase(SEI)on Zn anode and electrolyte engineering to regulate zinc ion solvated sheath structure and transport behavior are summarized and ***,the perspectives for the future development of design strategies for dendrite-free Zn metal anode and long lifespan AZMBs are also given.

关键词： aqueous Zn metal batteries Zn metal anode Transport behavior Solvated structure Dendrite-free

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