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Maintenance,Repair,and Reinforcement Measures for Dilapidated Small and Medium-Sized Bridges

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Journal of Architectural Research and Development 2024年第1期8卷 62-67页

作者： xu meng Bo Liu Ji Li Zhi Tu China Merchants Chongqing Highway Engineering Testing Center Co. Ltd.Chongqing 400060China Chongoing Construction Science Research Inspection and Testing Co. Ltd.Chongqing 400060China

The paper initiates by exploring the importance of maintaining,repairing,and reinforcing bridges.Subsequently,it delves into routine and preventative maintenance measures tailored for small to medium-sized bridges.Additionally,the paper examines repair and reinforcement techniques specifically designed for deteriorated small and medium-sized bridges,encompassing methods for fortifying both the bridge foundation and upper and lower structures.Lastly,the paper proposes suggestions aimed at fostering discussions and exchanges on the development of maintenance and repair processes for deteriorated small and medium-sized bridges.

关键词： Dilapidated small and medium-sized bridges Maintenance Repair and reinforcement

Load Testing in Bridge Maintenance

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Journal of Architectural Research and Development 2024年第3期8卷 63-68页

作者： Bo Liu xu meng Ji Li Zhi Tu China Merchants Chongqing Highway Engineering Testing Center CO. LTD.Chongqing 400060China Chongqing Construction Science Research Inspection and Testing Co. Ltd.Chongqing 400060China

Highway bridges are a crucial component in road transportation networks.These bridges must be maintained according to usage requirements regularly.Test results must be considered before devising a maintenance plan.Load testing is a vital method of assessing the quality and performance of highway bridges.The outcomes of these tests facilitate the formulation of maintenance plans.This article examines the definition of load testing,its significance,and the process of execution,with the goal of providing support for bridge inspection and maintenance.

关键词： Highway bridge Load test and inspection Bridge maintenance

Analysis of Bridge Inspection Technology for Highway Reconstruction and Expansion

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Journal of World Architecture 2024年第1期8卷 40-44页

作者： xu meng Bo Liu Ji Li Zhi Tu China Merchants Chongqing Highway Engineering Testing Center Co. Ltd.Chongqing 400060China Chonging Construction Science Research Inspection and Testing Co. Ltd.Chongqing 400060China

This article focuses on bridge testing technologies in highway construction and expansion projects.It provides an overview of the inspection process for bridges in highway reconstruction and expansion projects,the main inspections,and strategies for improving the quality of inspections.Relevant units should conduct bridge inspections using appearance inspections,special inspections,and bearing capacity assessments in highway reconstruction and expansion projects.To effectively improve testing quality,relevant units should also focus on establishing and improving testing standards,strengthening material testing,and improving the overall quality of the testing personnel.This research aims to enhance the quality of highway reconstruction and expansion projects by supporting the sensible application of bridge inspection technology.

关键词： Expressway Reconstruction and expansion Bridge engineering Detection technology

Defect Inspection Technology for Steel Truss Suspension Bridges

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Journal of World Architecture 2024年第2期8卷 12-16页

Steel truss suspension bridges are prone to developing defects after prolonged use.These defects may include corrosion of the main cable or the steel truss.To ensure the normal and safe functioning of the suspension bridge,it is necessary to inspect for defects promptly,understand the cause of the defect,and locate it through the use of inspection technology.By promptly addressing defects,the suspension bridge’s safety can be ensured.The author has analyzed the common defects and causes of steel truss suspension bridges and proposed specific inspection technologies.This research is intended to aid in the timely discovery of steel truss suspension bridge defects.

关键词： Steel truss suspension bridge Defect Inspection technology

Decomposition mechanisms of nuclear-grade cationic exchange resin by advanced oxidation processes:Statistical molecular fragmentation model and DFT calculations

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Journal of Environmental Sciences 2024年第1期135卷 433-448页

作者： Xiang meng Pierre Désesquelles Lejin xu Department of Nuclear Engineering and Technology School of Energy and Power EngineeringHuazhong University of Science&TechnologyWuhan 430074China CNRS Laboratoire de Physique des Gaz et des PlasmasUniversitéParis-SaclayOrsay 91405France State Key Laboratory of Coal Combustion School of Energy and Power EngineeringHuazhong University of Science and TechnologyWuhan 430074China

The treatment and disposal of radioactive waste are presently facing great challenges.Spent ion exchange resins have become a focus of attention due to their high production and serious environmental risks.In this paper,a simplified model of cationic exchange resin is proposed,and the degradation processes of cationic resin monomer initiated by hydroxyl radicals(·OH)are clarified by combining statistical molecular fragmentation(SMF)model and density functional theory(DFT)calculations.The prediction of active sites indicates that the S-O bonds and the C-S bond of the sulfonic group are more likely to react during the degradation.The meta-position of the sulfonic group on the benzene ring is the most active site,and the benzene ring without the sulfonic group has a certain reactivity.The C11-C14 and C17-C20 bonds,on the carbon skeleton,are the most easily broken.It is also found that dihydroxy addition and elimination reactions play a major role in the process of desulfonation,carbon skeleton cleavage and benzene ring separation.The decomposition mechanisms found through the combination of physical models and chemical calculations,provide theoretical guidance for the treatment of complex polycyclic aromatic hydrocarbons.

关键词： Cationic exchange resin Statistical molecular fragmentation model Density functional theory Hydroxyl radical Decomposition mechanism

Polyethylenimine-modified graphene quantum dots promote endothelial cell proliferation

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Regenerative Biomaterials 2024年第2期3卷 137-146页

作者： Qirong xu Chen Li Xiangyan meng Xinghong Duo Yakai Feng School of Chemistry and Chemical Engineering Qinghai University for NationalitiesXining 810007PR China Key Laboratory of National Ethnic Affairs Commission of Resource Chemistry and Ecological Environment Protection on Qinghai-Tibet Plateau Xining 810007PR China institute of Disaster and Emergency Medicine Tianjin UniversityTianjin 300072PR China School of Chemical Engineering and Technology Tianjin UniversityTianjin 300350PR China Key Laboratory of Systems Bioengineering(Ministry of Education) Tianjin UniversityTianjin 300072PR China

Endothelial cell proliferation plays an important role in angiogenesis and treatment of related diseases.The aim of this study was to evaluate the effect of polyethylenimine(PEI)-modified graphene quantum dots(GQDs)gene vectors on endothelial cell prolifera-tion.The GQDs-cationic polymer gene vectors were synthesized by amidation reaction,and used to deliver pzNF580 gene to Human umbilical vein endothelial cells(HUVECs)for promoting their proliferation.The chemical modification of GQDs can ad-just gene vectors'surface properties and charge distribution,thereby enhancing their interaction with gene molecules,which could effectively compress the pZNF580 gene.The CCK-8 assay showed that the cell viability was higher than 80%at higher vector concentration(40μg/mL),demonstrating that the GQDs-cationic polymer gene vectors and their gene complex nanoparticles(NPs)having low cytotoxicity.The results of the live/dead cell double staining assay were consistent with those of the CCK-8 assay,in which the cell viability of the A-GQDs/pZNF580(94.38±6.39%),C-GQDs-PEI-polylactic acid-co-polyacetic acid(PLGA)/pZNF580(98.65±6.60%)and N-GQDs-PEI-PLGA/pZNF580(90.08±1.60%)groups was significantly higher than that of the Lipofectamine 2000/pzNF580(71.98±3.53%)positive treatment group.The results of transfection and western blot experiments showed that the vector significantly enhanced the delivery of plasmid to HUVECs and increased the expression of pZNF580 in HUVECs.In addition,the gene NPs better promote endothelial cell migration and proliferation.The cell migration rate and proliferation ability of C-GQDs-PEI-PLGA/pZNF580 and N-GQDs-PEI-PLGA/pZNF580 treatment groupS were higher than those of Lipofectamine 2000/pDNA treatment group.Modified GQDs possess the potential to serve as efficient gene carriers.They tightly bind gene molecules through charge and other non-covalent interactions,significantly improving the effciency of gene delivery and ensuring the smooth release of genes within the cell.This innovative strategy provides a

关键词： graphene quantum dots polyethylenimine ZNF580 gene endothelial cell proliferation

Green manufacturing for achieving carbon neutrality goal requires innovative technologies:A bibliometric analysis from 1991 to 2022

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Journal of Environmental Sciences 2024年第6期140卷 255-269页

作者： Sheng Zhang Xintian Wang Jiayu xu Qinqin Chen meng Peng Jiming Hao School of Environment Tsinghua UniversityBeijing 100084China School of Environment&Natural Resources Renmin University of ChinaBeijing 100872China State Environmental Protection Key Laboratory of Sources and Control of Air Pollution Complex Beijing 100084China

Recent years have seen a significant increase in interest in green manufacturing as a key driver of global carbon-neutral efforts and sustainable development.To find the research hotspots of green manufacturing and reveal future research trends,this study reviewed and analyzed research articles from the Web of Science database on green manufacturing from1991 to 2022 using a bibliometric method.The findings indicate a significant rise in the number of articles related to green manufacturing since the 2010s.Moreover,there has been an increase in the involvement of scholars from developing countries such as China and India in this field.Based on the literature review and bibliometric cluster analysis on green manufacturing,we believed that future research may continue following the lines of intelligent technology integration,adoption of frontier engineering techniques,and industry development in line with carbon reduction targets.A framework for future green manufacturing development is proposed,with a focus on Chinese policies.The framework could provide policy implications for developing countries looking to pursue opportunities for development in green manufacturing.

关键词： Green manufacturing Carbon neutrality Sustainable development Innovative technologies China

GNSS gyroscopes:determination of angular velocity and acceleration with very high-rate GNSS

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Satellite Navigation 2024年第1期5卷 74-90页

作者： Yun Shi Peiliang xu Yuanming Shu Xiaolin meng School of Geomatics Xi’an University of Science and TechnologyXi’an710054People’s Republic of China Disaster Prevention Research Institute Kyoto UniversityUjiKyoto611-0011Japan College of Marine Geosciences Ocean University of ChinaQingdaoPeople’s Republic of China School of Instrument Science and Engineering Southeast UniversityNanjing210096People’s Republic of China

Although global navigation satellite systems(GNSS)have been routinely applied to determine attitudes,there exists no literature on determining angular velocity and/or angular acceleration from GNSS.Motivated by the invention of computerized accelerometers of the correspondence author and following the success of accurately recovering translational velocity and acceleration waveforms from very high-rate GNSS precise positioning by xu and his collaborators in 2021,we propose the concept of GNSS gyroscopes and reconstruct angular velocity and acceleration from very high-rate GNSS attitudes by applying regularization under the criterion of minimum mean squared errors.The major results from the experiments can be summarized in the following:(i)angular velocity and acceleration waveforms computed by applying the difference methods to high-rate GNSS attitudes are too noisy and can be physically not meaningful and numerically incorrect.The same can be said about inertial measurement unit(IMU)attitudes,if IMU gyros are not of very high accuracy;(ii)regularization is successfully applied to reconstruct the high-rate angular velocity and acceleration waveforms from 50 Hz GNSS attitudes and significantly outperforms the difference methods,validating the proposed concept of GNSS gyroscopes.By comparing the angular velocity and acceleration results by using the difference methods and regularization,we find that the peak values of angular velocity and acceleration by regularization are much smaller by a maximum factor of 1.57 in the angular velocity to a maximum factor of 8662.53 times in the angular acceleration in the case of high-rate GNSS,and by a maximum factor of 1.26 in the angular velocity to a maximum factor of 2819.85 times in the angular acceleration in the case of IMU,respectively;and(iii)the IMU attitudes apparently lead to better regularized angular velocity and acceleration waveforms than the high-rate GNSS attitudes,which can well be explained by the fact that the former is of better accuracy than the latter.As

关键词： Angular velocity Angular acceleration High-rate GNSS GNSS attitudes GNSS gyroscopes Regularization

Danhongqing formula alleviates cholestatic liver fibrosis by downregulating long non-coding RNA H19 derived from cholangiocytes and inhibiting hepatic stellate cell activation

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Journal of Integrative Medicine 2024年第2期22卷 188-198页

作者： meng Li Yang Zhou Hui Zhu Lie-ming xu Jian Ping Institute of Liver Diseases Shuguang HospitalShanghai University of Traditional Chinese MedicineShanghai 201203China Preventive Treatment Center Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghai 200437 China Department of Gastroenterology Suzhou Traditional Chinese Medicine HospitalSuzhou 215000Jiangsu ProvinceChina Shanghai Key Laboratory of Traditional Chinese Medicine Shanghai 201203China Key Laboratory of Liver and Kidney Diseases(Ministry of Education) Shanghai 201203China

Objective:This study explores the mechanism of action of Danhongqing formula(DHQ),a compoundbased Chinese medicine formula,in the treatment of cholestatic liver fibrosis.Methods:In vivo experiments were conducted using 8-week-old multidrug resistance protein 2 knockout(Mdr2-/-)mice as an animal model of cholestatic liver fibrosis.DHQ was administered orally for 8 weeks,and its impact on cholestatic liver fibrosis was evaluated by assessing liver function,liver histopathology,and the expression of liver fibrosis-related proteins.Real-time polymerase chain reaction,Western blot,immunohistochemistry and other methods were used to observe the effects of DHQ on long non-coding RNA H19(H19)and signal transducer and activator of transcription 3(STAT3)phosphorylation in the liver tissue of Mdr2-/-mice.In addition,cholangiocytes and hepatic stellate cells(HSCs)were cultured in vitro to measure the effects of bile acids on cholangiocyte injury and H19 expression.Cholangiocytes overexpressing H19 were constructed,and a conditioned medium containing H19 was collected to measure its effects on STAT3 protein expression and cell activation.The intervention effect of DHQ on these processes was also investigated.HSCs overexpressing H19 were constructed to measure the impact of H19 on cell activation and assess the intervention effect of DHQ.Results:DHQ alleviated liver injury,ductular reaction,and fibrosis in Mdr2-/-mice,and inhibited H19expression,STAT3 expression and STAT3 phosphorylation.This formula also reduced hydrophobic bile acid-induced cholangiocyte injury and the upregulation of H19,inhibited the activation of HSCs induced by cholangiocyte-derived conditioned medium,and decreased the expression of activation markers in HSCs.The overexpression of H19 in a human HSC line confirmed that H19 promoted STAT3 phosphorylation and HSC activation,and DHQ was able to successfully inhibit these effects.Conclusion:DHQ effectively alleviated spontaneous cholestatic liver fibrosis in Mdr2-/-mice by inhibiting H19 upregulation in chol

关键词： Liver cirrhosis biliary Long non-coding RNA H19 Danhongqing formula Cholangiocyte Hepatic stellate cells STAT3 transcription factor