检索结果-南通市图书馆

Growing Knowledge of Stem Cells as a Novel Experimental Model in Developmental Toxicological Studies

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Chemical Research in Chinese Universities 2023年第3期39卷 342-360页

作者： REN Zhihua KU Tingting REN Mengyao LIANG Jiefeng NING Xia xu hanqing REN Danqin ZHOU Qunfang SANG Nan College of Environment and Resource Research Center of Environment and HealthShanxi UniversityTaiyuan030006P.R.China State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing100085P.R.China Shandong Key Laboratory of Environmental Processes and Health School of Environmental Science and EngineeringShandong UniversityQingdaoQingdao266237P.R.China National and Local Joint Engineering Research Center of Ecological Treatment Technology for Urban Water Pollution Wenzhou UniversityWenzhou325035P.R.China

The increasing production and extensive application of chemicals have led to their unintended release and contamination in the environment,posing a hazardous threat to wildlife and human *** studies have demonstrated that developmental toxicity could be induced by various emerging chemicals,causing abnormal embryonic and placental development,adverse pregnancy outcomes,obesity,and dysfunction of lipid metabolism in *** the currently-available experimental technology for developmental toxicological studies,an in vitro model based on stem cells showed promising performance in high-throughput screening of the early-stage developmental toxicity of emerging *** this review,the deleterious effects of environmental pollutants on stem cells were systemically assorted from the aspects of cytological dysfunction,self-renewal impairment,perturbation in embryoid body(EB)formation,and disruption of committed lineage *** toxicological data on the molecular level,including the altered expressions of gene and protein biomarkers,epigenomic regulation,and enhanced oxidative stress,were collected and summarized to provide the mechanism explanation for the link between environmental pollutant exposure and unfavorable phenotypes in stem *** advantage of the stem cell model in developmental toxicological studies was specifically *** the perspectives for stem cells were ultimately highlighted in the research field of environmental toxicology,especially developmental toxicology during the early stage of life.

关键词： Environmental pollutant Developmental toxicology Stem cell Early-stage life Health effect

Perspectives on Compound Flooding in Chinese Estuary Regions

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International Journal of Disaster Risk Science 2023年第2期14卷 269-279页

作者： hanqing xu Elisa Ragno Jinkai Tan Alessandro Antonini Jeremy D.Bricker Sebastiaan N.Jonkman Qing Liu Jun Wang Institute of Eco-Chongming(IEC) Key Laboratory of Geographic Information Science of Ministry of Education and School of Geographic SciencesEast China Normal UniversityShanghai200241China Faculty of Civil Engineering and Geosciences Delft University of Technology2628 CNDelftThe Netherlands School of Atmospheric Sciences and Key Laboratory of Tropical Atmosphere-Ocean System of Ministry of Education Sun Yat-sen UniversityZhuhai519082China Department of Civil and Environmental Engineering University of MichiganAnn ArborMI48109USA

Extreme surges and rainfall represent major driving factors for compound flooding in estuary regions along the Chinese *** combined effect of extreme surges and rainfall(that is,compound floods)might lead to greater impacts than if the drivers occurred in ***,understanding the frequency and severity of compound flooding is important for improving flood hazard assessment and compound flood resilience in coastal *** this study,we examined the dependence between extreme surges and corresponding rainfall events in 26 catchments along the Chinese coastline during typhoon and non-typhoon seasons using copula functions,to identify where the two drivers more often occur together and the implication for flood management in these *** found that the interaction between flood drivers is statistically significant in 10catchments located around Hainan Island(south)and Shanghai,where surge peaks occur mainly during the typhoon season and around the Bohai Sea(north),where surge peaks occur mainly during the non-typhoon *** further applied the copula-based framework to model the dependence between surge peaks and associated rainfall and estimate their joint and conditional probability in two specific locations—Hainan Island and the Bohai Sea,where the correlation between flood drivers is statistically *** observed that in Hainan Island where most of the surge peaks occur during the typhoon season,extreme rainfall events during the typhoon season are generally more intense compared to annual maxima *** contrast,around the Bohai Sea where surge peaks occur mainly outside the typhoon season,rainfall is less intense than annual maxima *** results show that the interaction between extreme surges and rainfall can provide valuable insight when designing coastal and urban infrastructure,especially in highly populated urban areas prone to both coastal and pluvial flooding,such as many Chinese coastal cities.

关键词： China Coastal catchments Compound flooding Copula function Extreme surge Optimal threshold

Environmental pollution,a hidden culprit for health issues

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Eco-Environment & Health 2022年第3期1卷 31-45页

作者： hanqing xu Yang Jia Zhendong Sun Jiahui Su Qian S.Liu Qunfang Zhou Guibin Jiang State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing100085China National and Local Joint Engineering Research Center of Ecological Treatment Technology for Urban Water Pollution and Zhejiang Provincial Key Lab for Subtropical Water Environment and Marine Biological Resources ProtectionWenzhou UniversityWenzhou325035China School of Environment Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of SciencesHangzhou310000China College of Resources and Environment University of Chinese Academy of SciencesBeijing100049China Institute of Environment and Health Jianghan UniversityWuhan430056China

The environmental and health impacts from the massive discharge of chemicals and subsequent pollution have been gaining increasing public *** unintended exposure to different pollutants,such as heavy metals,air pollutants and organic chemicals,may cause diverse deleterious effects on human bodies,resulting in the incidence and progression of different *** article reviewed the outbreak of environmental pollution-related public health emergencies,the epidemiological evidence on certain pollution-correlated health effects,and the pathological studies on specific pollutant *** recalling the notable historical life-threatening disasters incurred by local chemical pollution,the damning evidence was presented to criminate certain pollutants as the main culprit for the given health *** epidemiological data on the prevalence of some common diseases revealed a variety of environmental pollutants to blame,such as endocrine-disrupting chemicals(EDCs),fine particulate matters(PMs)and heavy *** retrospection of toxicological studies provided illustrative clues for evaluating ambient pollutant-induced health ***,environmental pollution,as the hidden culprit,should answer for the increasing public health burden,and more efforts are highly encouraged to strive to explore the cause-and-effect relationships through extensive epidemiological and pathological studies.

关键词： Environmental pollution Public health emergency Epidemiological evidence Pathological study Cause-and-effect relationship

Semantic Segmentation-Based Road Marking Detection Using Around View Monitoring System

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Journal of Shanghai Jiaotong university(Science) 2022年第6期27卷 833-843页

作者： xu hanqing YANG Ming DENG Liuyuan LI Hao WANG Chunxiang HAN Weibin YU Yuelong School of Electronic Information and Electrical Engineering Shanghai Jiao Tong UniversityShanghai 200240China SJTU-ParisTech Elite Institute of Technology Shanghai Jiao Tong UniversityShanghai 200240China SAIC Motor Corporation Limited Shanghai 200041China

Road marking detection is an important branch in autonomous driving,understanding the road *** recent years,deep-learning-based semantic segmentation methods for road marking detection have been arising since they can generalize detection result well under complicated environments and hold rich pixel-level semantic ***,the previous methods mostly study the training process of the segmentation network,while omitting the time cost of manually annotating pixel-level ***,the pixel-level semantic segmentation results need to be fitted into more reliable and compact models so that geometrical information of road markings can be explicitly *** order to tackle the above problems,this paper describes a semantic segmentation-based road marking detection method using around view monitoring system.A semiautomatic semantic annotation platform is developed,which exploits an auxiliary segmentation graph to speed up the annotation process while guaranteeing the annotation accuracy.A segmentation-based detection module is also described,which models the semantic segmentation results for the more robust and compact *** proposed detection module is composed of three parts:vote-based segmentation fusion filtering,graph-based road marking clustering,and road-marking *** under various scenarios show that the semantic segmentation-based detection method can achieve accurate,robust,and real-time detection performance.

关键词： autonomous driving semantic segmentation road marking detection

音频工作站系统“服务器轮转换位、不间断滚动升级”改造

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广播与电视技术 2008年第10期35卷 112-112,114,115页

作者：徐汉青河南人民广播电台

数字音频工作站系统由直接连接存储DAS系统升级为SAN存储架构系统,为保障24小时安全播出采取不间断、滚动升级。

关键词：直接存储DAS系统 SAN网络存储系统不间断滚动升级安全可靠先进

机遇与挑战:基于BERTopic的AI环境下图书馆主题文本挖掘

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情报科学 2024年第4期42卷 119-128页

作者：徐汉青滕广青宁波大学科学技术学院浙江慈溪315211 东北师范大学信息科学与技术学院吉林长春130117

【目的/意义】挖掘AI环境下图书馆主题文本分布特征,以期为图书馆智能化转型和服务升级提供实践参考和理论支持。【方法/过程】本研究基于Web of Science数据库核心集合,应用BERTopic模型对检索到的相关文献进行主题识别与知识结构提取... 详细信息

【目的/意义】挖掘AI环境下图书馆主题文本分布特征,以期为图书馆智能化转型和服务升级提供实践参考和理论支持。【方法/过程】本研究基于Web of Science数据库核心集合,应用BERTopic模型对检索到的相关文献进行主题识别与知识结构提取,以洞察AI在图书馆领域的研究现状和未来发展动向。【结果/结论】研究结果显示,AI环境下图书馆的研究主题主要可分为五类:图书馆智能化、馆藏资源开发、学术研究支持、信息资源建设、聊天机器人与智能代理。最后,结合主题内容分析,深入讨论了AI环境下图书馆的机遇与挑战。【创新/局限】研究工作采用先进的自然语言技术——BERTopic主题模型对AI环境下图书馆领域主题文本进行知识挖掘,未来的研究工作将纳入更广泛的数据来源,进行更加全面细致地研究。

关键词：人工智能图书馆 BERTopic 主题识别可视化

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6G移动通信网络:愿景、挑战与关键技术

中国科学：信息科学 2019年第8期49卷 963-987页

作者：赵亚军郁光辉徐汉青中兴通讯无线研究院算法部

随着5G网络开启规模商业部署,越来越多的研究机构及相关人员开始对下一代移动通信系统进行研究.本文将探讨10年后(2030年~)的6G概念.本文首先用4个关键词概括未来6G愿景:'智慧连接'、'深度连接'、'全息连接'和'泛在连接',而这4个关键词... 详细信息

随着5G网络开启规模商业部署,越来越多的研究机构及相关人员开始对下一代移动通信系统进行研究.本文将探讨10年后(2030年~)的6G概念.本文首先用4个关键词概括未来6G愿景:'智慧连接'、'深度连接'、'全息连接'和'泛在连接',而这4个关键词共同构成'一念天地,万物随心'的6G总体愿景.接着分析了实现6G愿景面临的技术需求与挑战,包括峰值吞吐量、更高能效、随时随地的连接、全新理论与技术,以及一些非技术挑战.然后分类给出了6G潜在关键技术:新频谱通信技术,包括太赫兹通信和可见光通信;基础性技术,包括稀疏理论(压缩感知)、全新信道编码、大规模天线、灵活频谱使用,以及基于AI的无线通信技术;专有技术特性,包括空天地海一体化网络和无线触觉网络.本文通过探讨6G愿景、需求与挑战,以及潜在关键技术,尝试勾勒出6G的整体框架,以期为后续展开6G研究提供方向性指引.

关键词： 6G 愿景太赫兹可见光通信压缩感知全自由度双工无线触觉网络

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长周期倒计时信号控制对排队消散特性的影响

城市交通 2016年第6期14卷 67-74页

作者：赵巍徐汉清天津市市政工程设计研究院天津300051

长周期和倒计时是中国相对于发达国家城市道路交叉口信号控制方案的两个独有特征。基于实证数据分析两类信号控制特征对车辆排队消散特性的影响。共观测天津市两处典型的长周期倒计时信号控制交叉口的7条直行车道。实证数据表明,中国城... 详细信息

长周期和倒计时是中国相对于发达国家城市道路交叉口信号控制方案的两个独有特征。基于实证数据分析两类信号控制特征对车辆排队消散特性的影响。共观测天津市两处典型的长周期倒计时信号控制交叉口的7条直行车道。实证数据表明,中国城市道路交叉口长周期倒计时信号控制下的排队消散过程大致可分为3个阶段:启动阶段、稳定阶段和上升阶段。通过有序样品聚类的方法确定3个阶段的分割点。这与HCM 2010等经典理论假设的排队消散特性明显不同,因此分析传统通行能力估计算法HCM 2010的适用性,并提出简单线性法、抛物线法和两段线法3种通行能力估计方法以减少传统方法估计中的误差。通过比较发现,抛物线与两段线拟合方法对通行能力的估计较为准确,均方根误差(RMSE)均小于30 pcu·h^(-1)。

关键词：城市交通信号控制排队消散特性通行能力有序样品聚类长周期倒计时

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垂直旋转圆盘边缘液体形态

北京航空航天大学学报 2019年第6期45卷 1203-1210页

作者：覃文隆樊未军石强徐汉卿张荣春北京航空航天大学能源与动力工程学院

为了解重力对旋转圆盘表面液体流动的影响,利用高速摄影,对垂直旋转圆盘边缘液体形态进行了试验研究。结果表明,与水平旋转圆盘边缘液体分为直接液滴、液柱和液膜3种形态不同,垂直旋转圆盘边缘液体分为液柱、液膜和柱膜纠缠3种形态。垂... 详细信息

为了解重力对旋转圆盘表面液体流动的影响,利用高速摄影,对垂直旋转圆盘边缘液体形态进行了试验研究。结果表明,与水平旋转圆盘边缘液体分为直接液滴、液柱和液膜3种形态不同,垂直旋转圆盘边缘液体分为液柱、液膜和柱膜纠缠3种形态。垂直旋转圆盘底部与顶部液体形态并不一致。底部未出现液膜形态,当流量不大于24 g/s时,为液柱形态;当流量大于等于30 g/s时,为柱膜纠缠形态。当流量为12~21 g/s、转速为1 000~2 100 r/min,顶部出现液膜形态;当流量小于12 g/s时,顶部为液柱形态;当流量大于12 g/s时,液柱形态消失,由柱膜纠缠形态取代。由于重力影响,垂直旋转圆盘边缘液体形态变化程度远大于水平旋转圆盘;在流量大到一定程度后,圆盘底部形成液柱形态需要的转速会大大增加。

关键词：旋转雾化器垂直旋转圆盘液体形态高速摄影雾化