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Approach from the laboratory to the field: New strategies in the control of mosquito-borne infectious diseases

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Science China Life Sciences 2025年第1期 303-305页

作者： Ziqian xu Lianpan dai Jun Liu National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID) National Institute for Viral Disease Control and PreventionChinese Center for Disease Control and Prevention CAS Key Laboratory of Pathogen Microbiology and Immunology Institute of MicrobiologyChinese Academy of Sciences

Vector-borne viruses, transmitted among humans and animal hosts through bites of vectors such as mosquitoes and ticks,pose a great and ongoing threat to public health and biosafety(Yang et al., 2022).Among them, dengue virus-induced epidemics, have dramatically increased worldwide in recent decades. The report released by the World Health Organization(WHO) at the end of 2023 showed that dengue epidemic globally surged in2023, with the number of reported cases nearing a historical peak.

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马克思恩格斯关于党的政治建设的探索与启示

学习论坛 2025年第1期 118-125页

作者：代红伟向绪伟天津师范大学马克思主义学院天津300387 南昌师范学院马克思主义学院江西南昌330032

政治建设是马克思主义政党的根本性建设。在创建和指导无产阶级政党的过程中,马克思、恩格斯围绕如何将无产阶级政党打造成为强大的政治组织进行了不断的理论建构和实践探索。他们从政治立场、政治纲领、政治目标、政治品格、政治信仰... 详细信息

政治建设是马克思主义政党的根本性建设。在创建和指导无产阶级政党的过程中,马克思、恩格斯围绕如何将无产阶级政党打造成为强大的政治组织进行了不断的理论建构和实践探索。他们从政治立场、政治纲领、政治目标、政治品格、政治信仰等方面深刻论述了无产阶级政党政治建设的科学意蕴,并在实践的基础上形成了坚持维护党的权威,构建科学严密的组织形式和组织原则,构建科学合理的制度体系等一系列无产阶级政党政治建设的基本经验。新时代新征程,要坚持马克思主义在意识形态领域的指导地位,夯实党的政治建设的思想基础;坚持和完善民主集中制,夯实党的政治建设的组织基础;坚持人民至上理念,夯实党的政治建设的群众基础;完善党内法规制度体系,夯实党的政治建设的制度基础。

关键词：马克思恩格斯无产阶级政党政治建设党的建设

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甘蓝型油菜蜡质相关基因的克隆与表达分析

农业生物技术学报 2017年第12期25卷 1918-1929页

作者：周燕黄小虎许代香贾乐东王瑞李加纳曲存民西南大学农学与生物科技学院/重庆市油菜工程技术研究中心西南大学农业科学研究院

植物叶片中,表皮蜡质对植物的生长发育和适应外界环境起着重要作用。本研究针对拟南芥(Arabidopsis thaliana)已发表的蜡质相关基因信息,基于生物信息学的方法获得以甘蓝型油菜(Brassica napus)品种中双11号为参考的10个蜡质相关基因的4... 详细信息

植物叶片中,表皮蜡质对植物的生长发育和适应外界环境起着重要作用。本研究针对拟南芥(Arabidopsis thaliana)已发表的蜡质相关基因信息,基于生物信息学的方法获得以甘蓝型油菜(Brassica napus)品种中双11号为参考的10个蜡质相关基因的44个拷贝序列。然后,以在抽薹期前后叶片蜡质差异明显的3对自然突变的甘蓝型油菜(L1050,P144和W481)为材料,利用同源克隆的方法获得这些拷贝成员在3对甘蓝型油菜中的核苷酸和蛋白序列,通过多重比对分析发现,甘蓝型油菜蜡质基因(wax inducer 2,WIN2)家族中的Bn WIN2C01在核苷酸与氨基酸水平上均存在稳定的突变位点。利用q RT-PCR分析基因Bn WIN2C01在甘蓝型油菜突变体材料抽薹期前后叶片中的表达情况,结果表明该基因在表皮蜡质合成前后的叶片中达到极显著差异水平(P<0.01),说明Bn WIN2C01基因的特异性表达可能影响了叶片蜡质的合成。本研究将有助于阐明叶表皮蜡质形成过程的分子机理,为提高油菜抗逆性提供一定的参考依据。

关键词：甘蓝型油菜蜡质蜡质基因(WIN2) 生物信息学分析同源克隆

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轮毂电动机驱动车辆并联式复合制动策略

江苏大学学报（自然科学版） 2025年第1期46卷 9-17页

作者：付翔肖帅徐超武汉理工大学汽车工程学院湖北武汉430070

基于并联式轮毂电动机驱动实车构型,分析影响制动能量回收效率的主要因素,采用联邦卡尔曼滤波纵向车速估计算法,提出了三层式复合制动控制策略.该策略中的制动决策层根据踏板输入信号和行驶状态来识别制动工况,并进入相应的制动模式.制... 详细信息

基于并联式轮毂电动机驱动实车构型,分析影响制动能量回收效率的主要因素,采用联邦卡尔曼滤波纵向车速估计算法,提出了三层式复合制动控制策略.该策略中的制动决策层根据踏板输入信号和行驶状态来识别制动工况,并进入相应的制动模式.制动控制层根据制动决策层的指令,在常规制动工况下通过粒子群优化(PSO)算法优化前、后轮电制动力矩分配,实现电池有效回收效率最大化;紧急制动工况下,通过模糊自整定PID算法实现车辆在不同附着路面上各轮滑移率的安全有效控制,优化了制动防抱死控制的鲁棒性,提高制动安全性.制动执行层响应制动控制层的指令,设计了电制动补偿机制,以迅速补偿调节各轮轮缸的压力误差,提高车辆制动稳定性.最后实车验证了该复合控制策略的有效性.

关键词：轮毂电动机驱动车辆并联式复合制动粒子群优化制动能量回收模糊自整定PID

Double [5]carbohelicene: facile synthesis, chiroptical properties,isomerization study, and lasing application

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Science China Chemistry 2025年第1期 233-240页

作者： Peipei Liu Yantong Li Meng-xiang Wu Hao Kang Xiao-Li Zhao Lin xu Linlin Liu Xiaodong Li Junfeng Fang Zhiwei Fang Ya Cheng Hai-Bo Yang Huakang Yu xueliang Shi State Key Laboratory of Petroleum Molecular & Process Engineering Shanghai Key Laboratory of Green Chemistry and Chemical ProcessesSchool of Chemistry and Molecular Engineering East China Normal University School of Physics and Optoelectronics South China University of Technology Institute of Polymer Optoelectronic Materials & Devices State Key Laboratory of Luminescent Materials & Devices South China University of Technology School of Physics and Electronic Science Engineering Research Center of Nanophotonics & Advanced Instrument Ministry of EducationEast China Normal University State Key Laboratory of Precision Spectroscopy School of Physics and Electronic Science East China Normal University

Double carbohelicenes have attracted considerable attention due to their aesthetic structures, distinct π-conjugation extension, inherent chirality, and intriguing optical and electronic properties. Herein, the concise de novo synthesis of a new double[5]carbohelicene 1 together with its chiroptical properties, isomerization process and lasing application is presented. 1 was synthesized by a simple protocol involving the formation of a 6,6′-bipentacene as the key intermediate. It is worth noting that1 existed as two diastereomers 1-PP/MM and 1-PM, which were successfully isolated and unambiguously confirmed by Xray crystallography. The optical resolution of the racemic 1-PP/MM was successfully achieved by chiral-phase highperformance liquid chromatography（HPLC）, and 1-PP and 1-MM were characterized by circular dichroism. Interestingly, it was found that 1-PP/MM could be completely isomerized to 1-PM upon heating, and the detailed thermodynamics and kinetics of the isomerization process were systematically investigated. 1-PM exhibited deep-red luminescence with emission maximum at 723 nm and fluorescence quantum yield as high as 32.95%. Consequently, we can showcase the lasing application of 1-PM by doping with epoxy resin to assemble a bottle microlaser spontaneously, which the lasing wavelength is 796.6 nm at a threshold of 0.8 m J cm-2. We believe that our studies, including the facile synthesis methodology, detailed isomerization studies, and lasing application, will shed some light on the design and synthesis of novel carbohelical systems with more functions.

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Unraveling the mysteries of volatile cycling and habitability on Earth and beyond

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National Science Review 2024年第6期11卷 8-9页

作者： Yi-Gang xu Ri-xiang Zhu Min-Han dai State Key Laboratory of Isotope Geochemistry Guangzhou Institute of Geochemistry Chinese Academy of Sciences State Key Laboratory of Lithosphere Evolution Institute of Geology and Geophysics Chinese Academy of Sciences State Key Laboratory of Marine Environmental Science Xiamen University

The origin and cycling of volatiles, including water, carbon dioxide, and nitrogen, are fundamental to the very existence of habitable planets. These volatile compounds, often taken for granted,are the lifeblood of planetary systems, influencing almost everything from atmospheric composition and climate regulation to deep Earth processes and the emergence of life.

关键词： cycling beyond earth habitability mysteries unraveling volatile

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甘蓝型油菜显性核不育系D3A的细胞学研究

西南大学学报（自然科学版） 2020年第1期42卷 16-21页

作者：许代香贾乐东王瑞马国强段谋正曲存民李加纳西南大学农学与生物科技学院/农业科学研究院

为明确甘蓝型油菜显性核不育两型系D3AB的花器官形态差异和不育材料D3A的花药败育时期与特点,并为进一步研究雄性不育机理奠定基础,分别对D3A与D3B不同时期的花蕾进行了形态学观察及细胞学研究.首先通过体视镜观察发现,D3A与D3B外观形... 详细信息

为明确甘蓝型油菜显性核不育两型系D3AB的花器官形态差异和不育材料D3A的花药败育时期与特点,并为进一步研究雄性不育机理奠定基础,分别对D3A与D3B不同时期的花蕾进行了形态学观察及细胞学研究.首先通过体视镜观察发现,D3A与D3B外观形态无明显差异,均能正常开花,且在雄蕊发育早期均表现正常,后期D3A雄蕊退化萎缩,花粉囊不能正常开裂;不育材料D3A子房柱头发育速度稍快于D3B.通过扫描电镜观察发现,D3A早期花药基部开始皱缩,表皮细胞排列紧密.随着花蕾发育,D3A花粉囊壁表皮细胞逐渐萎缩,最终塌陷且药室不能正常开裂释放花粉;D3B花粉囊始终呈现出紧致饱满状态,花药正常开裂,同时释放出大量成熟花粉粒.通过石蜡切片观察发现,不育材料D3A和可育材料D3B在花蕾发育早期,都能形成花粉母细胞,但与D3B相比,D3A花粉母细胞结构松散,且绒毡层已开始呈现液泡化状态;进入四分体时期,不育材料D3A的花粉囊中观察到高度液泡化的绒毡层细胞,且无四分体结构出现.实验结果表明:绒毡层细胞提前发生了降解而未向分泌型转化,使四分体时期丧失了发育过程中所必需的营养物质,从而不能形成小孢子并发育为成熟的花粉粒进行释放,因此认为D3A的败育属于绒毡层发育异常类型.

关键词：显性核不育花药败育绒毡层细胞学观察

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《中国近现代史纲要》网络教学研究

重庆教育学院学报 2011年第4期24卷 154-157页

作者：李志友徐占春代祥宜春学院政法学院江西宜春336000

《中国近现代史纲要》肩负着思想政治教育与历史教育的双重任务,也面临着思想政治教育与历史教育的双重困境。本文分析了运用网络手段教学《中国近现代史纲要》的必要性、可行性和实效性。

关键词：《中国近现代史纲要》网络教学研究

Numerical implementation of a modified Mohr–Coulomb model and its application in slope stability analysis

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Journal of Modern Transportation 2017年第1期25卷 40-51页

作者： xu xiang dai Zi-Hang College of Transportation and Civil Engineering Fujian Agriculture and Forestry University College of Civil Engineering Fuzhou University

The hyperbolic function proposed by Abbo- Sloan was employed not only to approach the Mohr- Coulomb criterion but also to express the plastic potential function. A better approximation to the Mohr-Coulomb yield and potential surfaces was achieved by increasing the transition angle and proven to be highly efficient in numerical convergence. When a Gaussian integral point goes into plastic state, two cases on yield stress adjustments were introduced. They may avoid solving the second derivative of the plastic potential function and the inverse matrix compared with the existing subroutine. Based on the above approaches, a fully implicit backward Euler integral regression algorithm was adopted. The two- and three-di- mensional user subroutines which can consider the asso- ciated or non-associated flow rule were developed on the platform of the finite element program--ABAQUS. To verify the reliability of these two subroutines, firstly, the numerical simulations of the indoor conventional triaxial compression and uniaxial tensile tests were performed, and their results were compared with those of the embedded Mohr-Coulomb model and the analytical approach. Then the main influential factors including the associated or non- associated flow rule, the judgment criteria of slope failure, and the tensile strength of soil were analyzed, and the application of the two-dimensional subroutine in the sta- bility analysis of a typical soil slope was discussed in detail through comparisons with the embedded model and the limit analysis method, which shows that this subroutine is more applicable and reliable than the latter two.

关键词： Hyperbolic yield function Plastic potentialfunction First derivative Stress adjustment Slopestability analysis