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Optoelectronics Letters 2023年第8期19卷 481-486页

作者： xiong lingyi YU Yangfei DUAN Shaoxiang LIU Bo LIN Wei YAO Yuan Institute of Modern Optics Tianjin Key Laboratory of Optoelectronic Sensor and Sensing Network TechnologyNankai UniversityTianjin 300350China Marine Protected Area Administration of Sansha City Sansha 573100China Southern Marine Science and Engineering Guangdong Laboratory Zhuhai 519000China

We proposed an ultra-high sensitivity triple-core fiber refractive index(RI)sensor with a modified Vernier effect for marine RI measurement and demonstrated it by numerical *** sensor composes a pair of parallelized spatial mode Mach-Zehnder interferometers(MZIs),both of which are involved in sensing,but possess different interfering *** designing an MZI RI fiber optic sensor based on Vernier effect in air,it is demonstrated that in the low RI such as air environment,only the modes involved in sensing interference are affected by the environment to generate Vernier *** the high RI marine environment,both sensing interferometer and reference interferometer need to be affected by the ambient RI to generate Vernier *** simulation results indicate that the proposed novel sensing structure can amplify its sensitivity from-15428 nm/RIU to-24857 nm/RIU in the marine environment.

关键词： interferometer fiber effect

从“克隆”到“本土”:一位华德福幼儿教师在文化冲突中专业成长的个案研究

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江苏第二师范学院学报 2021年第4期37卷 38-44页

作者：夏巍熊翎伊西华师范大学学前与初等教育学院四川南充637000 四川师范大学教育科学学院四川成都610101

在我国实践国外教育理念的幼儿教师未得到足够的关注,他们常常在文化冲突中陷入困境,自我专业成长受阻。研究呈现了一位在中国华德福幼儿园工作十余年教师的专业成长经历,运用文化适应理论考察该教师文化适应的过程及其影响因素,探索其... 详细信息

在我国实践国外教育理念的幼儿教师未得到足够的关注,他们常常在文化冲突中陷入困境,自我专业成长受阻。研究呈现了一位在中国华德福幼儿园工作十余年教师的专业成长经历,运用文化适应理论考察该教师文化适应的过程及其影响因素,探索其成功解决文化冲突、实现教育理念本土化的路径。研究发现个案教师因“克隆”华德福教育理论和方法产生“教”抑或“不教”、“智能化教学”抑或“非智能化教学”、“自然教育”抑或“应试教育”等冲突,借助专家引领、家园共育、工作坊组建,展开与文化差异、世俗观念及自身旧习的“博弈”,最终站在国际理解与文化自信的立场,通过反思性实践实现自我专业成长。

关键词：华德福文化冲突幼儿教师专业成长

体艺融合视野下冰雪运动教育的内涵、价值与路径探析

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当代体育科技 2022年第18期12卷 182-186页

作者：熊翎伊青谕西华师范大学学前与初等教育学院四川南充637000

近年来,冰雪运动备受关注,冰雪运动教育也逐渐成为教育改革的方向和趋势。该研究以体艺融合视角为立足点,通过文献分析法,总结出冰雪运动教育文化、艺术、学科三大内涵,分析出探索学科交叉,深化体教融合;贯穿教育始终,促进素质发展;聚... 详细信息

近年来,冰雪运动备受关注,冰雪运动教育也逐渐成为教育改革的方向和趋势。该研究以体艺融合视角为立足点,通过文献分析法,总结出冰雪运动教育文化、艺术、学科三大内涵,分析出探索学科交叉,深化体教融合;贯穿教育始终,促进素质发展;聚焦特色优势,创新冰雪教育三重价值,同时为冰雪运动教育的实施提出建议,期望能为学校建立新型人才培养体系和革新课程提供参考。

关键词：体艺融合冰雪运动冰雪运动教育内涵与价值

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The emerging role of nitric oxide in the synaptic dysfunction of vascular dementia

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Neural Regeneration Research 2025年第2期20卷 402-415页

作者： Xiaorong Zhang Zhiying Chen Yinyi xiong Qin Zhou Ling-Qiang Zhu Dan Liu Department of Pathology Affiliated Hospital of Jiujiang UniversityJiujiangJiangxi ProvinceChina Jiujiang Clinical Precision Medicine Research Center JiujiangJiangxi ProvinceChina Center for Cognitive Science and Transdisciplinary Studies Jiujiang UniversityJiangxi ProvinceChina Department of Neurology Affiliated Hospital of Jiujiang UniversityJiujiangJiangxi ProvinceChina Department of Rehabilitation Affiliated Hospital of Jiujiang UniversityJiujiangJiangxi ProvinceChina Department of Pathophysiology School of Basic MedicineTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

With an increase in global aging,the number of people affected by cerebrovascular diseases is also increasing,and the incidence of vascular dementia-closely related to cerebrovascular risk-is increasing at an epidemic ***,few therapeutic options exist that can markedly improve the cognitive impairment and prognosis of vascular dementia *** in Alzheimer’s disease and other neurological disorders,synaptic dysfunction is recognized as the main reason for cognitive *** oxide is one of the ubiquitous gaseous cellular messengers involved in multiple physiological and pathological processes of the central nervous ***,nitric oxide has been implicated in regulating synaptic plasticity and plays an important role in the pathogenesis of vascular *** review introduces in detail the emerging role of nitric oxide in physiological and pathological states of vascular dementia and summarizes the diverse effects of nitric oxide on different aspects of synaptic dysfunction,neuroinflammation,oxidative stress,and blood-brain barrier dysfunction that underlie the progress of vascular ***,we propose that targeting the nitric oxide-sGC-cGMP pathway using certain specific approaches may provide a novel therapeutic strategy for vascular dementia.

关键词： endoplasmic reticulum stress endothelial nitric oxide synthase gene therapy nitric oxide NO-sGC-cGMP pathway synaptic dysfunction vascular dementia

Three-dimensional fracture of UO2 ceramic pellets by phase field modeling

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 169-180页

作者： Wei xiong Xuan Ye Hongzhang Cheng Xiaoming Liu Institute of Nuclear and New Energy Technology Collaborative Innovation Center of Advanced Nuclear Energy Technology Key Laboratory of Advanced Reactor Engineering and Safety of Ministry of Education Tsinghua University State Key Laboratory of Nonlinear Mechanics Institute of Mechanics Chinese Academy of Sciences School of Engineering Science University of Chinese Academy of Sciences

Fracture is the primary failure type for the UO2ceramic pellets,which are operated under irradiation and thermal processes,and physically confined by the *** this work,by combining closely coupled physical processes of heat conduction,heat transfer,and mechanical deformation with the cohesive phase field framework,we proposed a high-precision modeling of quasistatic cracking of three-dimensional （3D） UO2ceramic fuel pellets under high temperature and *** simulation results agree well with the experimental results,indicating that the proposed method has the potential to capture 3D crack modes in the interested time ***,we studied the relation of the 3D fracture patterns of fuel pellets with the peak power *** was found that the power level plays a critical role in determining the competition between radial and circumferential cracks,as well as transverse penetrating cracks.

关键词： phase field method nuclear fuel pellet coupled thermo-mechanical model thermal fracture

Influence of introducing Zr,Ti,Nb and Ce elements on externally solidified crystals and mechanical properties of high-pressure die-casting Al–Si alloy

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 147-153页

作者： Junjie Li Wenbo Yu Zhenyu Sun Weichen Zheng Liangwei Zhang Yanling Xue Wenning Liu Shoumei xiong Center of Materials Science and Engineering School of Mechanical and Electronic Control EngineeringBeijing Jiaotong UniversityBeijing 100044China Traffic&Transportation Engineering Central South UniversityChangsha 410075China Shanghai Synchrotron Radiation Facility Shanghai Advanced Research InstituteChinese Academy of SciencesShanghai 201204China School of Materials Science and Engineering Tsinghua UniversityBeijing 100084China

High pressure die casting(HPDC)AlSi10Mn Mg alloy castings are widely used in the automobile *** can optimize the mechanical properties of castings through heat treatment,while the release of thermal stress arouses the deformation of large integrated ***,the development of non-heat treatment Al alloys is becoming the hot *** addition,HPDC contains externally solidified crystals(ESCs),which are detrimental to the mechanical properties of *** achieve high strength and toughness of non-heat treatment die-casting Al-Si alloy,we used AlSi9Mn alloy as matrix with the introduction of Zr,Ti,Nb,and *** influences on ESCs and mechanical properties were systematically investigated through three-dimensional reconstruction and thermodynamic *** results reveal that the addition of Ti increased ESCs'size and porosity,while the introduction of Nb refined ESCs and decreased ***,large-sized Al_3(Zr,Ti)phases formed and degraded the mechanical *** introduction of Ce resulted in the poisoning effect and reduced mechanical properties.

关键词： aluminium alloy high-pressure die-casting externally solidified crystals non-heat treatment

Kupffer细胞在非酒精性脂肪肝病中的作用

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生命的化学 2019年第3期39卷 464-471页

作者：徐芳芷熊令伊万敬员杨森重庆医科大学重庆市生物化学与分子药理学重点实验室

非酒精性脂肪性肝病(non-alcoholic fatty liver disease, NAFLD)是一种无过量饮酒史、以肝细胞脂肪变性和脂肪贮积为特征的临床病理综合征。Kupffer细胞是位于肝脏中的特殊巨噬细胞,是先天免疫中的重要组成部分,在肝脏疾病中起关键作... 详细信息

非酒精性脂肪性肝病(non-alcoholic fatty liver disease, NAFLD)是一种无过量饮酒史、以肝细胞脂肪变性和脂肪贮积为特征的临床病理综合征。Kupffer细胞是位于肝脏中的特殊巨噬细胞,是先天免疫中的重要组成部分,在肝脏疾病中起关键作用。多项研究表明,Kupffer细胞在NAFLD的发生发展过程中起重要作用。本文总结了Kuffer细胞在NAFLD疾病发生发展中的多重作用,旨在为NAFLD的治疗提供一个有效的靶点。

关键词：非酒精性脂肪肝病(NAFLD) Kupffer细胞脂质堆积氧化应激炎症反应

Adaptive-basis decomposition-based low-rank network for efficient non-uniform motion deblurring

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Optoelectronics Letters 2025年第1期21卷 43-50页

作者： CHEN Lei xiong Qingbo ZHANG Wei LI Runde School of Software Henan University School of Applied Technology China University of Labor Relations

In this study, we present a unified sparsity-driven framework that significantly enhances motion deblurring performance by integrating two key components: a custom-designed dataset and a low-rank module(LRM). This framework leverages the inherent sparsity of per-pixel blur kernels to bolster both deblurring accuracy and model interpretability. Firstly, we propose an adaptive-basis decomposition-based deblurring(ADD) approach, which constructs a tailored training dataset to enhance the generalization capacity of the deblurring network. The ADD framework adaptively decomposes motion blur into sparse basis elements, effectively addressing the intricacies associated with non-uniform blurs. Secondly, an LRM is proposed to improve the interpretability of deblurring models as a plug-and-play module, primarily designed to identify and harness the intrinsic sparse features in sharp images. A series of ablation studies have been conducted to substantiate the synergistic advantages of combining the proposed ADD with the LRM for overall improvement in deblurring efficacy. Subsequently, we empirically demonstrate through rigorous experimentation that incorporating the LRM into an existing Uformer network leads to substantial enhancement in reconstruction performance. This integration yields a sparsity-guided low-rank network(SGLRN). Operating under the overarching principle of sparsity, SGLRN consistently outperforms state-of-the-art methods across multiple standard deblurring benchmarks. Comprehensive experimental results, assessed through quantitative metrics and qualitative visual evaluations, provide compelling evidence of its effectiveness. The overall deblurring results are available at Google Drive.

关键词： Image enhancement

An intelligent active probing and trace-back scheme for IoT anomaly detection

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Digital Communications and Networks 2024年第1期10卷 168-181页

作者： Luying Wang lingyi Chen Neal N.xiong Anfeng Liu Tian Wang Mianxiong Dong School of Computer Science and Engineering Central South UniversityChangsha 410083China Department of Computer Science and Mathematics Sul Ross State UniversityAlpineTX 79830USA Artificial Intelligence and Future Networks Beijing Normal University&UICZhuhai 519087China Department of Information and Electronic Engineering Muroran Institute of TechnologyMuroran 050-8585Japan

Due to their simple hardware,sensor nodes in IoT are vulnerable to attack,leading to data routing blockages or malicious tampering,which significantly disrupts secure data *** Intelligent Active Probing and Trace-back Scheme for IoT Anomaly Detection(APTAD)is proposed to collect integrated IoT data by recruiting Mobile Edge Users(MEUs).(a)An intelligent unsupervised learning approach is used to identify anomalous data from the collected data by MEUs and help to identify anomalous nodes.(b)Recruit MEUs to trace back and propose a series of trust calculation methods to determine the trust of nodes.(c)The last,the number of active detection packets and detection paths are designed,so as to accurately identify the trust of nodes in IoT at the minimum cost of the network.A large number of experimental results show that the recruiting cost and average anomaly detection time are reduced by 6.5 times and 34.33%respectively,while the accuracy of trust identification is improved by 20%.

关键词： Anomaly detection Internet of things Integrating data collection Mobile edge users Intelligent

Kupffer细胞在APAP所致肝损伤中作用研究进展

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生命的化学 2019年第1期39卷 104-111页

作者：杨森周旭徐芳芷熊令伊张美霞万敬员重庆医科大学生物化学与分子药理学重点实验室重庆400016

对乙酰氨基酚所致肝损伤(acetaminophen-induced liver injury, AILI)是一类普遍的药物源性肝损伤(drug-induced liver injury, DILI),是造成急性肝衰竭(acute liver failure, AIF)的主要原因。Kupffer细胞为肝脏固有巨噬细胞,是机体先天免疫重要组成部分。Kupffer具有促炎和抗炎的双重作用,通过识别损伤相关模式分子(damage-associated molecular patterns, DAMPs)激活细胞内炎症信号,释放促炎因子、抗炎因子和趋化因子。Kupffer在AILI氧化应激、细胞招募、炎症反应、肝再生和纤维化等过程起着重要作用,对AILI的发生、发展及转归有着重要的影响。

关键词： AILI Kupffer细胞作用