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Combined MELD and blood lipid level in evaluating the prognosis of decompensated cirrhosis

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World Journal of Gastroenterology 2010年第11期16卷 1397-1401页

作者： Jiang, Ming Liu, Fei xiong, wu-Jun Zhong, Lan Xu, Wen Xu, Fei Liu, Yan-Bing Tongji Univ Shanghai E Hosp Affiliated Dept Gastroenterol Shanghai 200120 Peoples R China

AIM: To evaluate the prognostic value of the combined model for end-stage liver disease (MELD) and blood lipid level in patients with decompensated cirrhosis. METHODS: A total of 198 patients with decompensated cirrhosis were enrolled into the study. The values of triglyceride (TG), cholesterol (TC), high density lipoproteins (HDL) and low density lipoprotein (LDL) of each patient on the fi rst day of admission were retrieved from the medical records, and MELD was calculated. All the patients were followed up for 1 year. The relationship between the change of blood lipid level and the value of MELD score was studied by analysis of variance. The prognostic factors were screened by multivariate Cox proportional hazard model. Draw Kaplan-Meier survival curves were drawn. RESULTS: Forty-f ive patients died within 3 mo and 83 patients died within 1 year. The levels of TG, TC, HDL and LDL of the death group were all lower than those of the survivors. The serum TG, TC, HDL and LDL levels were lowered with the increase of the MELD score. Multivariate Cox proportional hazard model showed that MELD ≥18 and TC ≤2.8 mmol/L were independent risk factors for prognosis of decompensated cirrhosis. Survival analysis showed that MELD ≥18 combined with TC ≤ 2.8 mmol/L can clearly discriminate between the patients who would survive and die in 1 year. CONCLUSION: MELD ≥18 and TC ≤2.8 mmol/L are two important indexes to predict the prognosis of patients with decompensated cirrhosis. Their combination can effectively predict the long-term prognosis of patients with decompensated cirrhosis.

关键词： Cirrhosis Model of end-stage liver disease Blood lipid Prognosis Survival time

Analysis method and experimental study of ice accumulation detection signal based on Lamb waves

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Chinese Journal of Aeronautics 2024年第8期37卷 388-403页

作者： Yanxin ZHANG Hongjian ZHANG Xian YI Binrui wu Xianlei GUAN Jianjun xiong Key Laboratory of Icing and Anti/De-icing China Aerodynamics Research and Development CenterMianyang 621000China State Key Laboratory of Aerodynamics China Aerodynamics Research and Development CenterMianyang 621000China

A quantitative identification method for in-flight icing has the capability to significantly enhance the safety of aircraft *** guided waves have the unique advantage of detecting icing in a relatively large area,but quantitative identification of ice layers is a *** this paper,a quantitative identification method of ice accumulation based on ultrasonic guided waves is ***,a simulation model for the wave dynamics of piezoelectric coupling in three dimensions is established to analyze the propagation characteristics of Lamb waves in a structure consisting of an aluminum plate and an ice *** wavelet transform method is utilized to extract the Time of Flight(ToF)or Time of Delay(ToD)of S_(0)/B_(1) mode waves,which serves as a characteristic parameter to precisely determine and assess the level of ice ***,an experimental system is developed to evaluate the feasibility of Lamb waves-based icing real-time detection in the presence of spray ***,a combination of the Hampel median filter and the moving average filter is developed to analyze ToF/ToD *** simulation results reveal a positive correlation between geometric dimensions(length,width,thickness)of the ice layer and ToF/ToD of B1 mode waves,indicating their potential as indicators for quantifying ice *** results of real-time icing detection indicate that ToF/ToD will reach greater peak values with the growth of the arbitrary-shaped ice layer until saturation to effectively predict the simulation *** study lays a foundation for the practical application of quantitative icing detection via ultrasonic guided waves.

关键词： Ice Ice accumulation Ultrasonic sensor Ultrasonic guided wave Lamb wave Wavelet transform

Evolution of tribo-magnetization during sliding of ferromagnetic materials

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Friction 2024年第5期12卷 906-918页

作者： Fumin GAO Laibin ZHANG Jin ZHOU Yi xiong Jing wu Jianchun FAN China University of Petroleum-Beijing Beijing102249China Key Laboratory of Oil and Gas Safety and Emergency Technology Ministry of Emergency ManagementBeijing102249China

Sliding-induced subsurface microstructure evolution is believed to be decisive for determining the friction and wear performance of metallic contacts as well as the development of *** expects to develop a new prediction method of wear state by elucidating the correlation between subsurface microstructure evolution and corresponding magnetic domain ***,subsurface microstructure evolution including crystal and magnetic domain under tribological action is investigated *** results demonstrate that dislocation mediated plastic deformation decisively influences microstructural changes during tribological contact,further determining the magnetic domain ***,sliding-induced plastic deformation causes an increase in the width of magnetic domains,but depth-dependent derived microstructure formed under severe plastic deformation such as the refined grains and sub-grains,in turn,promoted the refinement of magnetic domains and their discontinuity,forming depth-dependent magnetic domain *** results are helpful to clarify the evolution of tribo-magnetization and the pinning effect of dislocations on magnetic domains.

关键词： tribology magnetic domain microstructure tribo-magnetization dislocations

Rational design, synthesis and prospect of biodegradable magnesium alloy vascular stents

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Journal of Magnesium and Alloys 2023年第9期11卷 3012-3037页

作者： Senwei Wang Chengao Du Xin Shen xiong wu Sihui Ouyang Jun Tan Jia She Aitao Tang Xianhua Chen Fusheng Pan College of Materials Science and Engineering Chongqing UniversityChongqingChina National Engineering Research Center for Mg Alloys Chongqing UniversityChongqingChina Beijing Amsinomed Medical Co LtdBeijingChina

Biodegradable magnesium(Mg) alloys are expected to be promising materials for cardiovascular stents(CVS), which can avoid the longterm clinical problems of current CVS, such as in-stent restenosis, late stent thrombosis, etc. Mg alloy stents exhibit superior biocompatibility and tunable biodegradability, compared with conventional permanent metallic stents. However, the poor formability and non-uniform corrosion of Mg alloy stents hinder their clinical application of CVS. This review focuses on the development of Mg alloys for CVS in recent *** to the results of bibliometric analysis, we analyzed different biodegradable Mg alloy systems. Moreover, the structural design strategies for Mg alloy stents that can reduce the stress concentration, as well as the surface modification methods to control the corrosion behavior and biological performance of Mg alloy stents are also highlighted. At last, this review systematically discussed the potential directions and challenges of biodegradable magnesium stents(BMgS) in cardiovascular fields.

关键词： Mg alloy micro-tube Biodegradable Mg stent Alloying design Structural design Functional properties

Underwater polarization image restoration based on logarithmic transformation and dark channel

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Optoelectronics Letters 2020年第2期16卷 149-153页

作者： LIU Xue-yan ZHANG Jian-lei YIN Ya-fang YANG Yi ZHANG Chao wu xiong-xiong School of Electronic Engineering Xi'an University of Posts and TelecommunicationsXi'an 710121China Xi'an Institute of Applied Optics Xi'an 710065China

The visibility of the underwater image is reduced due to the backscattering and signal attenuation, especially in highly turbid media. In this paper, we propose a polarization-based underwater image restoration method using logarithmic transformation and dark channel. Logarithmic transformation is first performed while maintaining the degree of polarization of the scene to increase the details of the images. Then we calculate the backscatter value through dark channel to estimate the degree of polarization of backscatter. The restored image can be obtained by the polarimetric recovery method. The experimental results illustrate the capabilities of the proposed method.

关键词： polarization channel image

An ion-percolating electrolyte membrane for ultrahigh efficient and dendrite-free lithium metal batteries

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InfoMat 2023年第12期5卷 77-86页

作者： Yu-Ting Xu Sheng-Jia Dai Xiao-Feng Wang xiong-Wei wu Yu-Guo Guo Xian-Xiang Zeng School of Chemistry and Materials Science Hunan Agricultural UniversityChangshaHunanthe People's Republic of China Key Laboratory of Physics and Technology for Advanced Batteries(Ministry of Education) College of PhysicsJilin UniversityChangchunthe People's Republic of China Hunan Province Yinfeng New Energy Co. Ltd.ChangshaHunanthe People's Republic of China CAS Key Laboratory of Molecular Nanostructure and Nanotechnology CAS Research/Education Center for Excellence in Molecular SciencesBeijing National Laboratory for Molecular Sciences(BNLMS)Institute of ChemistryChinese Academy of Sciences(CAS)Beijingthe People's Republic of China University of Chinese Academy of Sciences Beijingthe People's Republic of China

The development of lithium(Li)metal batteries has been severely limited by the formation of lithium dendrites and the associated catastrophic failure and inferior Coulombic efficiency which caused by non-uniform or insufficient Li^(+)supply across the electrode-electrolyte ***,a rational strategy is to construct a robust electrolyte that can allow efficient and uniform Li^(+)transport to ensure sufficient Li^(+)supply and homogenize the Li plating/***,we report an ion-percolating electrolyte membrane that acts as a stable Li^(+)reservoir to ensure a near-single Li^(+)transference number(0.78)and homogenizes Li^(+)migration to eradicate dendrite growth,endowing Li//LFP cell with an ultrahigh average Coulombic efficiency(ca.99.97%)after cycling for nearly half of a year and superior cycling stability when pairing with LiCoO_(2) with limited Li amount and LiNi_(0.8)Mn_(0.1)Co_(0.1)O_(2).These estimable attributes demonstrate significant potential of utility value for the ion-percolating electrolyte.

关键词： dendrite interface ionic transference number lithium metal battery solid electrolyte

Hepatocellular adenoma with malignant transformation in male patients with non-cirrhotic livers

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Chinese Journal of Cancer 2015年第5期34卷 217-224页

作者： Song-Lin An Li-Ming Wang Wei-Qi Rong Fan wu Wei Sun Wei-Bo Yu Li Feng Fa-Qiang Liu Fei Tian Jian-xiong wu Department of Abdominal Surgery Cancer Institute and HospitalChinese Academy of Medical Sciences and Peking Union Medical College Department of Pathology Cancer Institute and HospitalChinese Academy of Medical Sciences and Peking Union Medical College

Introduction:Hepatocellular adenomas(HCAs),with a risk of malignant transformation into hepatocellular carcinoma(HCQ,classically develop in young women who are taking oral *** is now clear that HCAs may also occur in ***,it is rarely reported that HCAs with malignant transformation occur in male patients with non-cirrhotic *** study aimed to characterize the malignancy of HCAs occurring in male ***:All patients with HCAs with malignant transformation who underwent hepatectomy at the Cancer Institute and Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College between January 1,1999 and December 31,2011 were enrolled in the *** clinical characteristics as well as radiologic and pathologic data were ***:HCAs with malignant transformation were observed in 5 male patients with non-cirrhotic livers,but not in female *** alpha-fetoprotein(AFP) levels were higher in patients with HCAs with malignant transformation than in patients with HCAs without malignant *** diameters of the tumors with malignant transformation were larger than 5 cm in 3 cases and smaller than 5 cm in 2 *** 5 patients were all alive without recurrence by the end of the study *** disease-free survival times of the 5 patients were 26,48,69,69,and 92 ***:Our results indicate that resection would be advised even if the presumptive diagnosis is adenoma smaller than 5 cm in diameter,especially in male patients.

关键词：恶性转化肝硬化患者胞腺恶性肿瘤化合物肝细胞癌肿瘤医院

Synergism of preintercalated manganese ions and lattice water in vanadium oxide cathodes for high-capacity and long-life Zn-ion batteries

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Journal of Energy Chemistry 2024年第9期96卷 709-717页

作者： Mengjing wu Rongrong Li Kai Yang Lijiang Yin Weikang Hu xiong Pu Key Laboratory of the Ministry of Education for Advanced Catalysis Material Institute of Physical ChemistryCollege of Chemistry and Materials ScienceZhejiang Normal UniversityJinhua 321004ZhejiangChina CAS Center for Excellence in Nanoscience Beijing Key Laboratory of Micro-nano Energy and SensorBeijing Institute of Nanoenergy and NanosystemsChinese Academy of SciencesBeijing 101400China School of Nanoscience and Engineering University of Chinese Academy of SciencesBeijing 100049China Chilwee Power Co.Ltd. Changxing 313100ZhejiangChina

Aqueous Zn-ion batteries(AZIBs)are recognized as a promising energy storage system with intrinsic safety and low cost,but its applications still rely on the design of high-capacity and stable-cycling cathode *** this work,we present an intercalation mechanism-based cathode materials for AZIB,*** vanadium oxide with pre-intercalated manganese ions and lattice water(noted as MVOH).The synergistic effect between Mn^(2+)and lattice H_(2)O not only expands the interlayer spacing,but also significantly enhances the structural *** in-situ and ex-situ characterizations clarify the Zn^(2+)/H^(+)co–(de)intercalation mechanism of MVOH in aqueous *** demonstrated remarkable structure stability,excellent kinetic behaviors and ion-storage mechanism together enable the MVOH to demonstrate satisfactory specific capacity of 450 mA h g^(−1)at 0.2 A g^(−1),excellent rate performance of 288.8 mA h g^(−1)at 10 A g^(−1)and long cycle life over 20,000 cycles at 5 A g^(−1).This work provides a practical cathode material,and contributes to the understanding of the ion-intercalation mechanism and structural evolution of the vanadium-based cathode for AZIBs.

关键词： Zn-ion batteries Vanadium oxide Pre-intercalation Lattice water Manganese ion

Large-scale manufacturing of functional single-atom ink for convenient glucose sensing

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Nano Research 2024年第8期17卷 7256-7263页

作者： Muyu Yan Xiaofei Zhu Can xiong Xiao Han Zhenggang Xue Yuen wu Department of Endocrinology Institute of Endocrine and Metabolic DiseasesThe First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230001China Deep Space Exploration Laboratory University of Science and Technology of ChinaHefei 230026China NEST Laboratory Department of PhysicsDepartment of ChemistryCollege of ScienceShanghai UniversityShanghai 200444China Center of Advanced Nanocatalysis(CAN) Department of Applied ChemistryUniversity of Science and Technology of ChinaHefei 230026China

Printing techniques hold great potential in the manufacture of electronics such as sensors,micro-supercapacitors,and flexible ***,developing large-scale functional conductive inks with appropriate rheological properties and active components still remains a ***,through optimizing the formulations of ink,iron single sites supported N-doped carbon black(Fe_(1)-NC)inks can serve as both conductive electrodes and high-reactive catalysts to realize convenient glucose detection,which pronouncedly reduces the dosage of enzyme and simplifies the sensors *** detail,utilizing in-situ pyrolysis method,Fe_(1)-NC single-atom catalysts(SACs)are prepared in bulk(dekagram-level).The batched Fe_(1)-NC SACs materials can be uniformly mixed with modulated ink to realize the screen printing with high resolution and ***,the whole scalable preparation and ink-functional process can be extended to various metals(including Co,Ni,Cu,and Mn).The introduction of highly active Fe_(1)-NC sites reduces the amount of enzyme used in glucose detection by at least 50%,contributing to the cost reduction of *** strategy in harnessing the SACs onto the carbon inks thus provides a broad prospect for the low-cost and large-scale printing of sensitive sensing devices.

关键词： large-scale manufacturing single-atom inks screen printing glucose sensing low enzyme dosage