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Pathogenicity of Klebsiella pneumonia(KpC4)infecting maize and mice

Journal of Integrative Agriculture 2016年第7期15卷 1510-1520页

作者： HUANG Min LIN Li WU Yi-xin Honhing Ho HE Peng-fei LI guo-zhi HE Peng-bo xiong guo-ru YUAN Yuan HE Yue-qiu Faculty of Plant Protection Yunnan Agricultural UniversityKunming 650201P.R.China Agriculture College and Urban Modem Agriculture Engineering Research Center Kunming UniversityKunming 650214P.R.China College of Agronomy and Biotechnology Yunnan Agricultural UniversityKunming 650201P.R.China Department of Biology State University of New YorkNew Paltz 12561USA College of Animal Science and Technology Yunnan Agricultural UniversityKunming 650201P.R.China Institute of Tropical Bioscience and Biotechnology Chinese Academy of Tropical Agricultural Sciences(CATAS)Haikou 570102P.R.China National and Local Joint Engineering Research Center for Screening and Application of Microbial Strains Kunming 650236P.R.China

Recently, a new bacterial top rot disease of maize has frequently appeared in many areas of Yunnan Province, China. The pathogen of the disease was identified as Klebsiella pneumoniae （KpC4）, which is well known to cause pulmonary and urinary diseases in humans and animals and occasionally exists as a harmless endophyte in plants. To evaluate the viru- lence of the maize pathogen to maize and mice, we inoculated maize and mice with routine inoculation and intraperitoneal injection respectively according to Koch＇s postulates. The results showed that KpC4 and the clinical strain K. pneumoniae 138 （Kp138） were all highly pathogenic to maize and mice and the strain re-isolated from diseased mice also caused typical top rot symptoms on maize by artificial inoculation. It is highlighting that a seemingly dedicated human/animal pathogen could cause plant disease. This is the first report of K. pneumoniae, an opportunistic pathogen of human/animal, could infect maize and mice. The findings serve as an alert to plant, medical and veterinarian scientists regarding a potentially dangerous bacterial pathogen infecting both plants and animals/humans. The maize plants in the field could serve as a reservoir for K. pneumoniae which might infect animals and probably humans when conditions are favorable. The new findings not only are significant in the developing control strategy for the new disease in Yunnan, but also serve as a starting point for further studies on the mechanism of pathogenesis and epidemiology of K. pneumoniae.

关键词： Klebsiella pneumoniae maize top rot disease isolation and identification pathogenicity tests white mouse

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Absorption mechanism of SO_(3)on various alkaline absorbents in the presence of SO_(2)

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Journal of Environmental Sciences 2025年第3期149卷 268-277页

作者： Junxiang guo Jin xiong Yuran Li Jirigele Qinggele Tingyu Zhu Shougang Group Research Institute of Technology Beijing 100043China Beijing Key Laboratory of Green Recyclable Process for Iron&Steel Production Technology Beijing 100043China CAS Key Laboratory of Green Process and Engineering Institute of Process EngineeringInnovation Academy for Green ManufactureChinese Academy of SciencesBeijing 100190China WISDRI City Environment Protection Engineering Limited Company Wuhan 430205China

Sulfur trioxide(SO_(3))as a condensable particle matter has a significant influence on atmospheric visibility,which easily arouses formation of *** is imperative to control the SO_(3)emission from the industrial flue *** commonly used basic absorbents,including Ca(OH)_(2),MgO and NaHCO_(3)were selected to explore the effects of temperature,SO_(2)concentration on the SO_(3)absorption,and the reaction mechanism of SO_(3)absorption was further *** suitable reaction temperature for various absorbents were proposed,Ca(OH)_(2)at the high temperatures above 500°C,MgO at the low temperatures below 320°C,and NaHCO_(3)at the temperature range of 320–500°*** competitive absorption between SO_(2)and SO_(3)was found that the addition of SO_(2)reduced the SO_(3)absorption on Ca(OH)_(2)and NaHCO_(3),while had no effect on *** order of the absorption selectivity of SO_(3)follows MgO,NaHCO_(3)and Ca(OH)_(2)under the given conditions in this *** absorption process of SO_(3)on NaHCO_(3)follows the shrinking core model,thus the absorption reaction continues until NaHCO_(3)was exhausted with the utilization rate of nearly 100%.The absorption process of SO_(3)on Ca(OH)_(2)and MgO follows the grain model,and the dense product layer hinders the further absorption reaction,resulting in low utilization of about 50%for Ca(OH)_(2)and *** research provides a favorable support for the selection of alkaline absorbent for SO_(3)removal in application.

关键词： Alkali absorbent Sulfur trioxide Selectivity Shrinking core model Grain model

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The photo-based treatment technology simultaneously removes resistant bacteria and resistant genes from wastewater

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Journal of Environmental Sciences 2025年第2期148卷 243-262页

作者： Zicong guo Xiang Tang Wenjun Wang Zhangxiong Luo Yuxi Zeng Nan Zhou Zhigang Yu Dongbo Wang Biao Song Chengyun Zhou Weiping xiong College of Environmental Science and Engineering and Key Laboratory of Environmental Biology and Pollution Control(Ministry of Education) Hunan UniversityChangsha 410082China Fujian Provincial Key Laboratory of Soil Environmental Health and Regulation College of Resources and EnvironmentFujian Agriculture and Forestry UniversityFuzhou 350002China School of Resources and Environment Hunan University of Technology and BusinessChangsha 410205China Australian Centre for Water and Environmental Biotechnology The University of QueenslandBrisbaneQLD 4072Australia

Because of the recent widespread usage of antibiotics,the acquisition and dissemination of antibiotic-resistance genes(ARGs)were prevalent in the majority of ***,the biological wastewater treatment processes used in wastewater treatment plants have a limited efficiencies of antibiotics resistant bacteria(ARB)disinfection and ARGs degradation and even promote the proliferation of ***,ARB and ARGs in effluent pose potential risks if they are not further *** oxidation is considered a promising disinfection technology,where the photocatalytic process generates many free radicals that enhance the interaction between light and deoxyribonucleic acid(DNA)for ARB elimination and subsequent degradation of *** reviewaims to illustrate the progress of photocatalytic oxidation technology for removing antibiotics resistant(AR)from wastewater in recent *** discuss the sources and transfer of ARGs in *** overall removal efficiencies of ultraviolet radiation(UV)/chlorination,UV/ozone,UV/H_(2)O_(2),and UV/sulfate-radical based system for ARB and ARGs,as well as the experimental parameters and removal mechanisms,are systematically *** contribution of photocatalytic materials based on TiO_(2) and g-C_(3)N_(4) to the inactivation of ARB and degradation of ARGs is highlighted,producingmany free radicals to attack ARB and ARGs while effectively limiting the horizontal gene transfer(HGT)in ***,based on the reviewed studies,future research directions are proposed to realize specific photocatalytic oxidation technology applications and overcome current challenges.

关键词： Antibiotics resistant genes Antibiotics resistant bacteria Photocatalytic oxidation

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A low-cost wide bandgap polymer based on carboxylate substituted thiazole enables efficient organic solar cells with remarkable batch-to-batch reproducibility

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SCIENCE CHINA-CHEMISTRY 2025年第2期68卷 733-744页

作者： Zhu, Xiaodong Lei, Yuchen Gao, Jianhong He, Yanjun Liu, Jinsicheng guo, Qian Gao, Xiang xiong, Liwei Wang, Xunchang Yang, Renqiang Liu, Zhitian Wuhan Inst Technol Hubei Engn Technol Res Ctr Optoelect & New Energy Sch Mat Sci & Engn Hubei Key Lab Plasma Chem & Adv Mat Wuhan 430205 Peoples R China Jianghan Univ Sch Optoelect Mat & Technol Key Lab Optoelect Chem Mat & Devices Minist Educ Wuhan 430056 Peoples R China

Constructing the low-cost, high-efficiency, and good batch-to-batch reproducibility polymer donor is vitally important for the application of organic solar cells. Herein, we develop a structurally simple carboxylate-substituted thiazole as an electron-withdrawing building block to construct a low-cost polymer, PBTTzE, containing a facilely prepared chlorinated benzo[1,2-b:4,5-b ']dithiophene (BDTCl) donor unit. Benefiting from synergistic electron deficient effects of chlorination and ester group and C=N, as well as the noncovalent interaction of S & ctdot;O and S & ctdot;N, PBTTzE exhibits a deep HOMO energy level (-5.59 eV), and a planar skeleton structure. When combined with the IT-4F acceptor, the polymer (54 kDa) demonstrated a champion PCE of 15.87%, which is the highest value in the IT-4F-based binary devices to date. Moreover, PBTTzE exhibits excellent batch-to-batch reproducibility due to its very similar PCEs within a range of 43-76 kDa. In addition, an alloyed state and complementary absorption can be formed between PM6 and PBTTzE. Therefore, in a ternary device with PBTTzE added to the PM6:BTP-eC9 blend, a top PCE of 18.76% is achieved due to the suppressed energy loss, prolonged exciton diffusion distance, and improved charge transport. Our work demonstrates that the carboxylate-substituted thiazole is a highly promising acceptor unit for constructing low-cost and high-performance polymers.

关键词： carboxylate substituted thiazole polymer donor low-cost batch-to-batch reproducibility organic solar cells

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Regulating crystallization and retarding oxidation in Sn-Pb perovskite via 1D cation engineering for high performance all-perovskite tandem solar cells

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Journal of Energy Chemistry 2025年第1期100卷 646-652页

作者： Ranran Liu Xin Zheng Zaiwei Wang Miaomiao Zeng Chunxiang Lan Shaomin Yang Shangzhi Li Awen Wang Min Li Jing guo Xuefei Weng Yaoguang Rong xiong Li Michael Grätzel Center for Mesoscopic Solar Cells Wuhan National Laboratory for OptoelectronicsHuazhong University of Science and TechnologyWuhan 430074HubeiChina Institute of Technology for Carbon Neutrality Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055GuangdongChina School of Chemistry Chemical Engineering and Life SciencesState Key Laboratory of Advanced Technology for Materials Synthesis and ProcessingWuhan University of Technology430070HubeiChina Suzhou Institute of Nano-Tech and Nano-Bionics(SINANO) Chinese Academy of SciencesSuzhou 215123JiangsuChina School of Physics and Optoelectronic Engineering Hainan UniversityHaikou 570228HainanChina

All-perovskite tandem solar cells have the potential to surpass the theoretical efficiency limit of single junction solar cells by reducing thermalization ***,the challenges encompass the oxidation of Sn^(2+)to Sn^(4+)and uncontrolled crystallization kinetics in Sn-Pb perovskites,leading to nonradiative recombination and compositional heterogeneity to decrease photovoltaic efficiency and operational ***,we introduced an ionic liquid additive,1-ethyl-3-methylimidazolium iodide (EMIMI) into Sn-Pb perovskite precursor to form low-dimensional Sn-rich/pure-Sn perovskites at grain boundaries,which mitigates oxidation of Sn^(2+)to Sn^(4+)and regulates the film-forming dynamics of Sn/Pb-based perovskite *** optimized single-junction Sn-Pb perovskite devices incorporating EMIMI achieved a high efficiency of 22.87%.Furthermore,combined with wide-bandgap perovskite sub-cells in tandem device,we demonstrate 2-terminal all-perovskite tandem solar cells with a power conversion efficiency of 28.34%,achieving improved operational stability.

关键词： All-perovskite tandem solar cells Sn-Pb perovskite 1D Regulated crystallization Antioxidation

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Relativistic two-fluid hydrodynamics with quantized vorticity from the nonlinear Klein–Gordon equation

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Communications in Theoretical Physics 2025年第2期77卷 161-171页

作者： Chi xiong Kerson Huang Minjiang Collaborative Center for Theoretical Physics Minjiang University Institute of Advanced Studies & School of Physical and Mathematical Science Nanyang Technological University Physics Department Massachusetts Institute of Technology Cambridge

We consider a relativistic two-fluid model of superfluidity, in which the superfluid is described by an order parameter that is a complex scalar field satisfying the nonlinear Klein–Gordon equation(NLKG). The coupling to the normal fluid is introduced via a covariant current–current interaction, which results in the addition of an effective potential, whose imaginary part describes particle transfer between superfluid and normal fluid. Quantized vorticity arises in a class of singular solutions and the related vortex dynamics is incorporated in the modified NLKG,facilitating numerical analysis which is usually very complicated in the phenomenology of vortex filaments. The dual transformation to a string theory description(Kalb–Ramond) of quantum vorticity, the Magnus force, and the mutual friction between quantized vortices and normal fluid are also studied.

关键词： relativistic superfluidity nonlinear Klein-Gordon field theory quantized vortices two-fluid model Kalb-Ramond field global string

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Residential Energy Scheduling With Solar Energy Based on Dyna Adaptive Dynamic Programming

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IEEE/CAA Journal of Automatica Sinica 2025年第2期12卷 403-413页

作者： Kang xiong Qinglai Wei Hongyang Li the Institute of Systems Engineering Macau University of Science and Technology IEEE the State Key Laboratory of Multimodal Artificial Intelligence Systems Institute of Automation Chinese Academy of Sciences the School of Artificial Intelligence University of Chinese Academy of Sciences

Learning-based methods have become mainstream for solving residential energy scheduling problems. In order to improve the learning efficiency of existing methods and increase the utilization of renewable energy, we propose the Dyna actiondependent heuristic dynamic programming(Dyna-ADHDP)method, which incorporates the ideas of learning and planning from the Dyna framework in action-dependent heuristic dynamic programming. This method defines a continuous action space for precise control of an energy storage system and allows online optimization of algorithm performance during the real-time operation of the residential energy model. Meanwhile, the target network is introduced during the training process to make the training smoother and more efficient. We conducted experimental comparisons with the benchmark method using simulated and real data to verify its applicability and performance. The results confirm the method's excellent performance and generalization capabilities, as well as its excellence in increasing renewable energy utilization and extending equipment life.

关键词： Adaptive dynamic programming (ADP) dynamic residential scenarios optimal residential energy management smart grid

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Three-dimensional fracture of UO_(2)ceramic pellets by phase field modeling

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Science China(Physics,Mechanics & Astronomy) 2025年第1期68卷 165-176页

作者： Wei xiong Xuan Ye Hongzhang Cheng Xiaoming Liu Institute of Nuclear and New Energy Technology Collaborative Innovation Center of Advanced Nuclear Energy TechnologyKey Laboratory of Advanced Reactor Engineering and Safety of Ministry of EducationTsinghua UniversityBeijing 100084China State Key Laboratory of Nonlinear Mechanics Institute of MechanicsChinese Academy of SciencesBeijing 100190China School of Engineering Science University of Chinese Academy of SciencesBeijing 100049China

Fracture is the primary failure type for the UO_(2)ceramic pellets,which are operated under irradiation and thermal processes,and physically confined by the *** this work,by combining closely coupled physical processes of heat conduction,heat transfer,and mechanical deformation with the cohesive phase field framework,we proposed a high-precision modeling of quasistatic cracking of three-dimensional(3D)UO_(2)ceramic fuel pellets under high temperature and *** simulation results agree well with the experimental results,indicating that the proposed method has the potential to capture 3D crack modes in the interested time ***,we studied the relation of the 3D fracture patterns of fuel pellets with the peak power *** was found that the power level plays a critical role in determining the competition between radial and circumferential cracks,as well as transverse penetrating cracks.

关键词： phase field method nuclear fuel pellet coupled thermo-mechanical model thermal fracture

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Formation and evolution of supercritical geofluid

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Science China Earth Sciences 2025年第1期68卷 39-51页

作者： Huaiwei NI Yilin XIAO Xiaolin xiong Xiandong LIU Chunxiao GAO Yi-Xiang CHEN Yunguo LI Wan-Cai LI Xuan guo Yang-Yang WANG Dong-Bo TAN Li ZHANG State Key Laboratory of Lithospheric and Environmental Coevolution University of Science and Technology of ChinaHefei230026China Deep Space Exploration Laboratory/School of Earth and Space Sciences University of Science and Technology of ChinaHefei230026China Guangzhou Institute of Geochemistry Chinese Academy of SciencesGuangzhou510640China School of Earth Sciences and Engineering Nanjing UniversityNanjing210023China State Key Lab of Superhard Materials Jilin UniversityChangchun130012China

In this work,we provide a comprehensive review on the formation,evolution,properties,and effects of supercritical *** Earth's interior,enhanced miscibility between H_(2)O and silicate by the addition of special components or by the increase of pressure and temperature gives rise to supercritical geofluid with a significant amount of both H_(2)O and silicate *** formation of supercritical geofluid in magmatic-hydrothermal systems,typified by pegmatite system,is governed by meltfluid critical *** formation of supercritical geofluid in metamorphic systems,typified by subducted slab,is governed by the second critical end *** results suggest that the presence of boron and fluorine in pegmatite system makes it possible to form supercritical geofluid at crustal depths,but the release of supercritical geofluid from subducted slab is withheld until almost 100 km depth.A major presence of both H_(2)O and depolymerized structural units(monomers,dimers,etc.)endows supercritical geofluid with unique physical properties including low density,low elastic moduli,low viscosity,high diffusivity,and high electrical *** geofluid can effectively mobilize a variety of elements even including high field strength elements and heavy rare earth *** chemical signatures of supercritical geofluid can be inherited by metasomatized mantle and mantle-derived melts,and this could give an explanation of the oxidation of arc *** separation of supercritical geofluid through the mechanism of spinodal decomposition leads to formation of a melt *** fluid inclusions recovered from subduction zone rocks and pegmatites are possible relics of supercritical *** geofluid can cause electrical anomaly and low seismic velocity near the top of subducted slab,and can be linked with intermediate-focus *** geofluid may have played a crucial role in the formation of pegmatites and associ

关键词： Supercritical geofluid Miscibility Subduction zone Pegmatite

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Advancing RAS inhibition:broad-spectrum targeting and tumor-selective activity of RMC-7977 in cancer therapy

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Science China(Life Sciences) 2025年第2期68卷 586-587页

作者： Qunli xiong Yaguang Zhang Laboratory of Gastrointestinal Tumor Epigenetics and Genomics Frontiers Science Center for Disease-related Molecular NetworkWest China HospitalSichuan UniversityChengdu 610041China Abdominal Oncology Ward Cancer CenterWest China HospitalSichuan UniversityChengdu 610041China

In cancer,the proto-oncogene RAS frequently mutates at codons 12,13,and 61,with these mutations propelling tumor progression by locking RAS proteins in their active,GTP-bound state(Pylayeva-Gupta et al.,2011;Yang et al.,2023).Despite the recent approval of small molecule inhibitors targeting KRAS(G12C)for non-small cell lung cancer(de Langen et al.,2023),a broadspectrum small molecule inhibitors for multiple RAS mutations have remained elusive.

关键词： cancer lung

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