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Dek219 encodes the diCER-LIKE1 protein that affects chromatin accessibility and kernel development in maize

Journal of Integrative Agriculture 2023年第10期22卷 2961-2980页

作者： xie si-di TIAN Ran ZHANG Jun-jie LIU Han-mei LI Yang-ping HU Yu-feng YU Guo-wu HUANG Yu-bi LIU Ying-hong State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China Sichuan Agricultural UniversityChengdu 611130P.R.China College of Life Science Sichuan Agricultural UniversityYa’an 625014P.R.China College of Agronomy Sichuan Agricultural UniversityChengdu 611130P.R.China Maize Research Institute Sichuan Agricultural UniversityChengdu 611130P.R.China

Chromatin accessibility plays a vital role in gene transcriptional ***,the regulatory mechanism of chromatin accessibility,as well as its role in regulating crucial gene expression and kernel development in maize(Zea mays)are poorly *** this study,we isolated a maize kernel mutant designated as defective kernel219(dek219),which displays opaque endosperm and embryo ***219 encodes the diCER-LIKE1(DCL1)protein,an essential enzyme in mi RNA *** of function of Dek219 results in significant reductions in the expression levels of most mi RNAs and histone *** research showed that the Heat shock transcription factor17(Hsf17)-Zm00001d016571 module may be one of the factors affecting the expression of histone *** results for transposase-accessible chromatin sequencing(ATAC-seq)indicated that the chromatin accessibility of dek219 is altered compared with that of wild type(WT),which may regulate the expression of crucial genes in kernel *** analyzing differentially expressed genes(DEGs)and differentially accessible chromatin regions(ACRs)between WT and dek219,we identified 119 candidate genes that are regulated by chromatin accessibility,including some reported to be crucial genes for kernel *** together,these results suggest that Dek219 affects chromatin accessibility and the expression of crucial genes that are required for maize kernel development.

关键词： maize kernel development chromatin accessibility histone miRNA

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Observation of topological charge transformations in acoustic vortex using passive periodic systems

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 140-147页

作者： di-Chao Chen xie Liu Changqing Xu Da-Jian Wu Ying Cheng Xiao-Jun Liu School of Physics and Technology Nanjing Normal University Key Laboratory of Modern Acoustics School of Physics Nanjing University

Vortex transmutation utilizes a periodic system, which not only enables the alteration of the topological charge(TC) of unstable input vortices but also facilitates their transformation into stable structures. This approach is crucial for investigating the characteristics of vortices in various wave systems. Here, we achieve acoustic vortex TC transmutation by employing a welldesigned dual-structured plate external system(DPES). The interactions between the acoustic vortex and the finite-order discrete rotational symmetry lead to the transformation of its topological charge when complete rotational symmetry is broken to Nthorder discrete symmetry. Our results experimentally demonstrate the acoustic vortex TC transmutation based on passive artificial structures, enabling numerous applications in particle manipulation and information multiplexing as well as advancing our understanding and control over free-space acoustic vortices.

关键词： acoustic vortex topological charge transformation artificial structure

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Actively tunable electromagnetically induced transparency in hybrid dirac-VO2 metamaterials

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Optoelectronics Letters 2025年第1期21卷 13-20页

作者： di Ke xie Meng XIA Huarong CHENG Anyu LIU Yu DU Jiajia Department of Optoelectronic Engineering Chongqing University of Post and Telecommunications Chongqing Key Laboratory of Autonomous Navigation and Microsystem Chongqing University of Posts and Telecommunications Department of Automation Chongqing University of Post and Telecommunications

In this paper, we present a metamaterial structure of dirac and vanadium dioxide（VO2） and investigate its optical properties using the finite-difference time-domain（FDTD） technique. Using the phase transition feature of VO2, the design can realize active tuning of the plasmon induced transparency（PIT） effect at terahertz frequency, thereby converting from a single PIT to a double-PIT. When VO2is in the insulating state, the structure is symmetric to obtain a single-band PIT effect. When VO2is in the metallic state, the structure turns asymmetric to realize a dual-band PIT effect. This design provides a reference direction for the design of actively tunable metamaterials. Additionally, it is discovered that the transparent window's resonant frequency and the Fermi level in this structure have a somewhat linear relationship. In addition, the structure achieves superior refractive index sensitivity in the terahertz band, surpassing 1 THz/RIU. Consequently, the design exhibits encouraging potential for application in refractive index sensors and optical switches.

关键词： Transparency

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Loss-of-function mutations of microRNA-142-3p promote ASH1L expression to induce immune evasion and hepatocellular carcinoma progression

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World Journal of Gastroenterology 2025年第1期31卷 126-145页

作者： Xing-Hui Yu Yan xie Jian Yu Kun-Ning Zhang Zhou-Bo Guo di Wang Zhao-Xian Li Wei-Qi Zhang Yu-Ying Tan Li Zhang Wen-Tao Jiang School of Medicine Nankai UniversityTianjin 300192China Tianjin Key Laboratory of Molecular diagnosis and Treatment of Liver Cancer Tianjin First Center HospitalTianjin 300192China Department of Liver Transplantation Tianjin First Center HospitalTianjin 300192China First Central Clinical School Tianjin Medical UniversityTianjin 300192China

BACKGROUND Hepatocellular carcinoma(HCC)has been a pervasive malignancy throughout the world with elevated *** therapeutic targets are beneficial to treat and predict the ***,the exact molecular mechanisms leading to the progression of HCC are still *** has shown that the microRNA-142-3p level decreases in HCC,whereas bioinformatics analysis of the cancer genome atlas database shows the ASH1L expression increased among liver tumor *** this paper,we will explore the effects and mechanisms of microRNA-142-3p and ASH1L affect the prognosis of HCC patients and HCC cell bioactivity,and the association between *** To investigate the effects and mechanisms of microRNA-142-3p and ASH1L on the HCC cell bioactivity and prognosis of HCC *** In this study,we grouped HCC patients according to their immunohistochemistry results of ASH1L with pathological tissues,and retrospectively analyzed the prognosis of HCC ***,explored the roles and mechanisms of microRNA-142-3p and ASH1L by cellular and animal experiments,which involved the following experimental methods:Immunohistochemical staining,western blot,quantitative real-time-polymerase chain reaction,flow cytometric analysis,tumor xenografts in nude mice,*** statistical methods involved in this study contained t-test,one-way analysis of variance,theχ^(2)test,the Kaplan-Meier approach and the log-rank *** In this study,we found that HCC patients with high expression of ASH1L possess a more recurrence rate as well as a decreased overall survival ***1L promotes the tumorigenicity of HCC and microRNA-142-3p exhibits reduced expression in HCC tissues and interacts with ASH1L through targeting the ASH1L 3′untranslated ***,microRNA-142-3p promotes apoptosis and inhibits proliferation,invasion,and migration of HCC cell lines in vitro via *** the exploration mechanism,we found ASH1L may promote an immunosuppressive mi

关键词： Hepatocellular carcinoma MicroRNA-142-3p ASH1L Immune evasion Tumor immune microenvironment Apoptosis

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Epigenetic regulation of plant immunity:from chromatin codes to plant disease resistance

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aBIOTECH 2023年第2期4卷 124-139页

作者： si-si xie Cheng-Guo Duan Shanghai Center for Plant Stress Biology and CAS Center for Excellence in Molecular Plant Sciences Chinese Academy of SciencesShanghai 200032China University of the Chinese Academy of Sciences Beijing 100049China

Facing a deteriorating natural environment and an increasing serious food crisis,bioengineering-based breeding is increasing in *** defend against pathogen infection,plants have evolved multiple defense mechanisms,including pathogen-associated molecular pattern(PAMP)-triggered immunity(PTI)and effector-triggered immunity(ETI).A complex regulatory network acts downstream of these PTI and ETI pathways,including hormone signal transduction and transcriptional *** recent years,increasing lines of evidence show that epigenetic factors act,as key regulators involved in the transcriptional reprogramming,to modulate plant immune ***,we summarize current progress on the regulatory mechanism of DNA methylation and histone modifications in plant defense *** addition,we also discuss the application of epigenetic mechanism-based resistance strategies in plant disease breeding.

关键词： Histone modification DNA methylation Transcriptional reprogramming Plant immunity disease resistance

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sintering kinetics involving grain growth and densification of Mg-PSZ nanopowders

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Journal of Iron and Steel Research International 2022年第7期29卷 1138-1144页

作者： Yi-ming She Jie-fu Lang di An Chao-wei si Xu-dong Luo Zhi-peng xie Jie-gang You School of Materials and Metallurgy University of Science and Technology LiaoningAnshan 114051LiaoningChina Institute of Advanced Structures Beijing Institute of TechnologyBeijing 100081China State Key Lab of New Ceramics and Fine Processing School of Materials Science and EngineeringTsinghua UniversityBeijing 100084China

sintering kinetics have been found to be effective in judging the evolution of *** using magnesium oxide-partially stabilized zirconia(Mg-PSZ)powder prepared by co-precipitation as raw materials,the evolution of densification and grain growth for Mg-PSZ ceramics were *** results indicated that the densification of samples was mainly controlled by grain boundary diffusion in intermediate sintering *** the sintering process,the grain growth mechanisms included normal grain growth,abnormal grain growth and solid solution drag-controlled grain ***,the apparent activation energy for grain growth of Mg-PSZ ceramics is lower than that of ZrO_(2)–Y_(2)O_(3)ceramics in the solid solution drag-controlled grain grow process,which will cause grain to grow *** sintering kinetics and microstructure of Mg-PSZ ceramics were studied,and the kinetic equation of grain growth at different temperatures was *** results show that the strength difference between Mg-PSZ and yttrium oxide-stabilized zirconia is closely related to the easy grain growth of Mg-PSZ ceramics.

关键词： Magnesium oxide-partially stabilized zirconia sintering kinetics Grain growth mechanism Densification mechanism sizing nozzle

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Velocity Constraints Based Approach for Online Trajectory Planning of High‑Speed Parallel Robots

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Chinese Journal of Mechanical Engineering 2022年第6期35卷 98-109页

作者： di Yang Fugui xie Xinjun Liu State Key Laboratory of Tribology in Advanced Equipment Department of Mechanical EngineeringTsinghua UniversityBeijing 100084China Beijing Key Lab of Precision/Ultra‑Precision Manufacturing Equipments and Control Tsinghua UniversityBeijing 100084China

High-speed parallel robots have been extensively utilized in the light ***,the influence of the nonlinear dynamic characteristics of high-speed parallel robots on system’s dynamic response and stable operation cannot be ignored during the high-speed reciprocating ***,trajectory planning is essential for efficiency and stability from pick-and-place(PAP)*** paper presents a method for planning the equal-height pick-and-place trajectory considering velocity constraints to improve the PAP efficiency and stability of high-speed parallel *** velocity constraints in the start-and-end points can reduce vibration from picking and placing,making the trajectory more suitable to complex beltline *** on velocity constraints,trajectory optimization includes trajectory smoothness and joint torque to optimize cycle time is carried *** paper proposes an online trajectory optimization *** using back propagation(BP)neural networks,the solution is simplified and can be solved in *** and experiments were carried out on the SR4 parallel *** results show that the proposed method improves the efficiency,smoothness,and stability of the *** paper proposes an online trajectory planning method which is velocity constraints based and can improve the efficiency and stability of high-speed parallel *** work of this research is conducive to finely applying high-speed parallel robots.

关键词： Trajectory planning High-speed parallel robot Velocity constraints BP neural network

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A Unified Method Based on SPA and Timing Attacks on the Improved RSA

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China Communications 2016年第4期13卷 89-96页

作者： JIA Fan xie di Beijing Jiaotong University China Information Technology & Security Test and Evaluation Center Beijing China

Nowadays the modular multiplications in many kinds of smartcards are utilized Montgomery's algorithm modular multiplier, so traditional SPA to RSA becomes invalid. An improved attack method is proposed based on SPA which just depends on the fact that there exist some subtle differences in each loop during the operation of cd mod n. At same time, compared with the traditional SPA, it doesn't need to select the clear text or some known message. Using this method, attacks can easy to discover the mode of RSA implementation and extract the bits of decryption key just based on a few collected traces. From the real attack test on several main kinds of smartcard, the private keys of RSA stored inside can be analyzed successfully.

关键词： power analysis SPA RSA attack SCA

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基于风廓线雷达的四川盆地西部强降水过程风场特征

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高原气象 2025年第1期44卷 240-252页

作者：胡迪谢晓林陈朝平周秋雪四川省气象台四川成都610072 高原与盆地暴雨旱涝灾害四川省重点实验室四川成都610072 四川省气象探测数据中心四川成都610072

根据暖区暴雨的分型(西南涡型、副热带高压边缘型、西南急流型和东南风型),选取四类天气背景下四川盆地西部(成都地区)的暴雨过程,利用风廓线雷达新资料,详细分析了青藏高原-四川盆地特殊地形下,不同类型暖区暴雨中典型强降水发生、发... 详细信息

根据暖区暴雨的分型(西南涡型、副热带高压边缘型、西南急流型和东南风型),选取四类天气背景下四川盆地西部(成都地区)的暴雨过程,利用风廓线雷达新资料,详细分析了青藏高原-四川盆地特殊地形下,不同类型暖区暴雨中典型强降水发生、发展时的风廓线特征。研究表明:(1)风廓线雷达资料可以很清楚地表现出对流层及边界层存在的中小尺度系统,不同类型强降水过程的风场演变特征同特殊地形与区域环流及天气系统的相互作用密切相关,除副高边缘型外,其他三种类型暖区暴雨典型过程发生前或发生时都出现了边界层东北风或偏东风;(2)垂直速度变化梯度大,直观地体现了这几次过程时间短、对流强的特征,降水开始后,向下的垂直速度明显减弱甚至转向的突变时期,代表气层中上升运动的明显增强,这种垂直速度的突变对于强降水的预测有指示意义;(3)垂直速度极值在强降水发生前或发生时会明显增大,并伴随有极值层降低的现象,水平风速极值和极值层有同步的增减趋势,大部分强降水过程发生前,中层都出现了中尺度急流,并伴随急流层的降低;(4)在这四种类型的暴雨过程中都有低空急流的参与,其中副高边缘型和西南涡型暴雨过程中,低空急流指数第一次增大都对降水的开始有1~2 h的预报提前量,而在东南风型和西南涡型过程中低空急流指数的突增预示了降水强度的增大。

关键词：风廓线雷达强降水低空急流暖区暴雨

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Science Letters:A new coding scheme in coded ultrasound using staggering repetition interval

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2009年第8期10卷 1213-1216页

作者： Cheng JIN si-ping CHEN Zheng-di QIN School of Biomedical Engineering and Instrument Science Zhejiang University Hangzhou 310027 China School of Medicine Shenzhen University Shenzhen 518060 China Nokia Corporation Tampere 33100 Finland

The increase of frame rate,though with the potential in a coded ultrasound system,is generally concomitant with the simultaneous transmission of a number of apertures,and in consequence leads to increased cross-talks between different *** view of this,a new coding scheme using staggering repetition interval was *** transmitting signals were constructed by repeating the two(or more) modulated codes using staggering repetition interval,and then allocated to and transmitted simultaneously among different *** decoding process was based on the subsection-matched filter under the assistance of different matched filters for different *** last the outputs of subsection-matched filtering were added *** changed the positions of cross-correlation(CC) peaks from coinciding,which resulted in an effective reduction of *** theoretical analysis and simulations showed that,the coding scheme can be used to reduce cross-talk,and a good cross-talk reduction will be achieved if the staggering delay is kept in an appropriate range.

关键词： Coded ultrasound Frame rate Cross-correlation (CC) Staggering Ultrasonic imaging

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