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我院静脉配置中心抗肿瘤药不合理用药分析

海峡药学 2024年第2期36卷 87-89页

作者：黄润生谢建平厦门大学附属第一医院福建厦门361000

目的分析我院静脉用药调配中心抗肿瘤药不合理用药情况,为临床抗肿瘤静脉用药提供参考,促进临床合理用药,保障肿瘤患者用药安全。方法我院2022年度住院静脉用药调配中心抗肿瘤用药医嘱10098份,依据药品说明书、相关文献等相关资料对87... 详细信息

目的分析我院静脉用药调配中心抗肿瘤药不合理用药情况,为临床抗肿瘤静脉用药提供参考,促进临床合理用药,保障肿瘤患者用药安全。方法我院2022年度住院静脉用药调配中心抗肿瘤用药医嘱10098份,依据药品说明书、相关文献等相关资料对87份不合理医嘱进行统计分析。结果我院2022年度住院静脉用药调配中心医嘱10098份,其中有不合理用药医嘱87份,每个科室均存在不合理用药情况,妇科的不合理医嘱数最多,其占比23.08%;静脉用药调配中心抗肿瘤药不合理用药情况主要包括溶媒错误(40.23%)、药物剂量不合理(29.89%)、给药顺序不合理(18.39%)、给药时间不合理(11.49%)。结论应加强我院的静脉用药调配中心抗肿瘤药不合理用药情况和抗肿瘤药溶媒管理,加强医师对抗肿瘤药物性质的认知,合理规范选择药物,同时药剂师应严格审核医嘱,以最大幅度减少不合理用药情况。

关键词：静脉用药调配中心抗肿瘤药不合理用药

Flattening Spectrum of a Broadband and Wavelength Stable Erbium Doped Superfluorescent Fiber Source

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Chinese Physics Letters 1999年第5期16卷 356-357页

作者： YANG Bao MING Hai GUO Yang xie jian-ping Department of Physics University of Science and Technology of ChinaHefei 230026

A technique is used to design the spectra in erbium doped superfluorescent fiber source experimentally and *** an erbium doped fiber with a 10m length and 300ppm concentration,a line width of about 42nm and high mean wavelength stability(<***/K,<0.2ppm/mW)were obtained by means of a suitable population distribution,and adjusting the ratio of backward to forward pump ***,its thermal characteristic is *** results will improve the performance of fiber optical gyroscope and fiber sensors,and will be applied in erbium doped fiber amplifier with flattening gain.

关键词： fiber amplifier Erbium

Characterization of Clusters in a Novel Nd^(3+)-Doped Polymer Optical Fiber

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Chinese Physics Letters 1998年第4期15卷 272-274页

作者： YANG Bao MING Hai ZHANG Qi-jin xie jian-ping Department of Physics University of Science and Technology of ChinaHefei 230026 Department of Materials Science and Engineering University of Science and Technology of ChinaHefei 230026

A step index-type Nd^(3+) -doped polymer optical fiber(POF)was prepared by using bulk polymerization of solution of Nd^(3+) -octanoate(NOA)and methyl and methacrylate.A method of wide-angle x-ray diffraction was used to measure the solubility of *** a high concentration Nd^(3+) doped POF,a residual absorption at 810nm could not be saturated,which is attributed to the high clustered ion rate in the Nd^(3+) POF.A model based on the rate equations to infer the clustered ion rate by the measurement of transmission is presented.

关键词： POF saturated attributed

HIV感染者/AIDS患者疾病接受度现状及相关因素研究

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中国感染控制杂志 2024年第8期23卷 1016-1022页

作者：秦子琪曹桂英谢建平王笑李怡轩陆乔悦王红红肖雪玲中南大学湘雅护理学院湖南长沙410013 长沙市第一医院湖南长沙410005

目的了解人类免疫缺陷病毒(HIV)感染者/艾滋病(AIDS)患者疾病接受度现状及其相关因素,以指导临床制定干预措施,并为改善其临床结局提供实证依据。方法采用便利抽样法选取在某医院AIDS定点治疗门诊接受治疗的555例HIV感染者/AIDS患者,收... 详细信息

目的了解人类免疫缺陷病毒(HIV)感染者/艾滋病(AIDS)患者疾病接受度现状及其相关因素,以指导临床制定干预措施,并为改善其临床结局提供实证依据。方法采用便利抽样法选取在某医院AIDS定点治疗门诊接受治疗的555例HIV感染者/AIDS患者,收集研究对象的一般资料、疾病接受度、疾病自我管理效能和临床结局(即生活质量、CD4+T淋巴细胞计数、HIV病毒载量)。结果HIV感染者/AIDS患者疾病接受度平均为(26.08±5.34)分。多元线性回归分析结果显示,宗教信仰、疾病自我管理效能是影响患者疾病接受度的相关因素(均P<0.05),可解释HIV感染者/AIDS患者疾病接受度30.4%的变异,且患者的疾病接受度与其生活质量紧密相关(P<0.001)。结论HIV感染者/AIDS患者的疾病接受度处于中等水平。在临床工作中医务人员应充分考虑患者的宗教信仰情况和疾病自我管理效能水平,以制定针对性的干预措施,提高患者疾病接受度,从而进一步促进患者获得更高的生活质量。

关键词：人类免疫缺陷病毒艾滋病疾病接受度临床结局生活质量

Boundary Diffraction Method for Aperture Near-Field Diffraction

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Chinese Physics Letters 1999年第11期16卷 811-813页

作者： xie jian-ping WU Wei-min FANG Hui SUN Xiao-hong WU Yun-xia MING Hai Department of Physics University of Science and Technology of ChinaHefei 230026

The boundary diffraction method is introduced to analyze the near-field diffraction of a subwavelength aperture. A self-consistent formula of boundary diffraction suitable to near field is derived. The near-field diffraction patterns of slits and circular apertures are obtained. The influence of incident light polarization on these diffraction patterns is also shown. These results are in good agreement with other theoretical and experimental results.

关键词： boundary circular Boundary

Quantitative characterizations of anisotropic dynamic properties in organic-rich shale with different kerogen content

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Petroleum Science 2024年第2期21卷 855-865页

作者： jian-Yong xie Yan-ping Fang Xing-Hua Wu jian'er Zhao Jun-Cheng Dai Jun-Xing Cao Ji-Xin Deng State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Chengdu University of TechnologyChengdu610059SichuanChina Key Lab of Earth Exploration&Information Techniques of Ministry of Education Geophysical InstituteChengdu University of TechnologyChengdu610059SichuanChina PetroChina Southwest Oil&Gasfield Company Chengdu610017SichuanChina

Understanding the quantitative responses of anisotropic dynamic properties in organic-rich shale with different kerogen content(KC)is of great significance in hydrocarbon exploration and *** controlled experiments with a single variable is challenging for natural shales due to their high variations in components,diagenesis conditions,or pore *** employed the hot-pressing technique to construct 11 well-controlled artificial shale with varying *** artificial shale samples were successive machined into prismatic shape for ultrasonic measurements along different *** revealed bedding perpendicular P-wave velocities are more sensitive to the increasing KC than bedding paralleling velocities due to the preferential alignments of *** elastic stiffnesses except C_(13)are generally decreasing with the increasing KC,the variation of C_(1) and C_(33)on kerogen content are more sensitive than those of C_(44)and C_(66).Apparent dynamic mechanical parameters(v and E)were found to have linear correlation with the true ones from complete anisotropic equations independent of KC,which hold value towards the interpretation of well logs consistently across formations,Anisotropic mechanical parameters(ΔE and brittlenessΔB)tend to decrease with the reducing KC,withΔB showing great sensitivity to KC *** the range of low KC(10%)shale,compilation of data from natural organic rich-shales globally verified the similar systematic relationships that can be empirically used to predict the fraction of KC in shales.

关键词： Elastic properties Organic shale Anisotropy Kerogen content Physical modeling

Research on thermal insulation materials properties under HTHP conditions for deep oil and gas reservoir rock ITP-Coring

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Petroleum Science 2024年第4期21卷 2625-2637页

作者： Zhi-Qiang He He-ping xie Ling Chen jian-ping Yang Bo Yu Zi-Jie Wei Ming-Zhong Gao State Key Laboratory of Intelligent Construction and Healthy Operation and Maintenance of Deep Underground Engineering College of Water Resource and Hydropower Sichuan University Guangdong Provincial Key Laboratory of Deep Earth Sciences and Geothermal Energy Exploitation and Utilization Institute of Deep Earth Sciences and Green Energy College of Civil and Transportation Engineering Shenzhen University School of Mechanical Engineering Sichuan University College of Polymer Science and Engineering Sichuan University

Deep oil and gas reservoirs are under high-temperature conditions, but traditional coring methods do not consider temperature-preserved measures and ignore the influence of temperature on rock porosity and permeability, resulting in distorted resource assessments. The development of in situ temperaturepreserved coring(ITP-Coring) technology for deep reservoir rock is urgent, and thermal insulation materials are key. Therefore, hollow glass microsphere/epoxy resin thermal insulation materials(HGM/EP materials) were proposed as thermal insulation materials. The materials properties under coupled hightemperature and high-pressure(HTHP) conditions were tested. The results indicated that high pressures led to HGM destruction and that the materials water absorption significantly increased; additionally,increasing temperature accelerated the process. High temperatures directly caused the thermal conductivity of the materials to increase; additionally, the thermal conduction and convection of water caused by high pressures led to an exponential increase in the thermal conductivity. High temperatures weakened the matrix, and high pressures destroyed the HGM, which resulted in a decrease in the tensile mechanical properties of the materials. The materials entered the high elastic state at 150.C, and the mechanical properties were weakened more obviously, while the pressure led to a significant effect when the water absorption was above 10%. Meanwhile, the tensile strength/strain were 13.62 MPa/1.3%and 6.09 MPa/0.86% at 100.C and 100 MPa, respectively, which meet the application requirements of the self-designed coring device. Finally, K46-f40 and K46-f50 HGM/EP materials were proven to be suitable for ITP-Coring under coupled conditions below 100.C and 100 MPa. To further improve the materials properties, the interface layer and EP matrix should be optimized. The results can provide references for the optimization and engineering application of materials and thus technical su

关键词： Deep oil and gas reservoir rock In situ temperature-preserved coring (ITP-Coring) Hollow glass microsphere/epoxy resin thermal insulation materials (HGM/EP materials) High-temperature and high-pressure (HTHP) Physical and mechanical properties

Measurement of the Optical Coherence of a Femtosecond Pulsed Laser by Shearing Interferometry with a Double-Frequency Grating

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Chinese Physics Letters 1998年第1期15卷 32-34页

作者： MING Hai QIAN jiang-yuan xie jian-ping A.B.Fedotov X.Xiao M.M.T.Loy Department of Physics University of Science and Technology of ChinaHefei 230026 Department of Physics Hong Kong University of Science&TechnologyClear Water BayKowloonHong KongChina

Shearing interferometry of an ion-etched holographic double-frequency grating is used to measure the optical coherence of femtosecond pulsed *** experimental results show that the optical coherence of the femtosecond light beam is not only related to the spectral width and size of the light source but is also related to the pulse duration and mode-locked laser *** results of theoretical analysis and numerical calculation are also *** of this research is also discussed.

关键词： Femto holographic interferometry

Accurate simulations of pure-viscoacoustic wave propagation in tilted transversely isotropic media

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Petroleum Science 2024年第2期21卷 866-884页

作者： Qiang Mao jian-ping Huang Xin-Ru Mu Ji-Dong Yang Yu-jian Zhang Geosciences Department China University of Petroleum(East China)Qingdao266580ShandongChina Pilot National Laboratory for Marine Science and Technology(Qingdao) Qingdao266207ShandongChina

Forward modeling of seismic wave propagation is crucial for the realization of reverse time migration(RTM) and full waveform inversion(FWI) in attenuating transversely isotropic media. To describe the attenuation and anisotropy properties of subsurface media, the pure-viscoacoustic anisotropic wave equations are established for wavefield simulations, because they can provide clear and stable wavefields. However, due to the use of several approximations in deriving the wave equation and the introduction of a fractional Laplacian approximation in solving the derived equation, the wavefields simulated by the previous pure-viscoacoustic tilted transversely isotropic(TTI) wave equations has low accuracy. To accurately simulate wavefields in media with velocity anisotropy and attenuation anisotropy, we first derive a new pure-viscoacoustic TTI wave equation from the exact complex-valued dispersion formula in viscoelastic vertical transversely isotropic(VTI) media. Then, we present the hybrid finite-difference and low-rank decomposition(HFDLRD) method to accurately solve our proposed pure-viscoacoustic TTI wave equation. Theoretical analysis and numerical examples suggest that our pure-viscoacoustic TTI wave equation has higher accuracy than previous pure-viscoacoustic TTI wave equations in describing q P-wave kinematic and attenuation characteristics. Additionally, the numerical experiment in a simple two-layer model shows that the HFDLRD technique outperforms the hybrid finite-difference and pseudo-spectral(HFDPS) method in terms of accuracy of wavefield modeling.

关键词： Pure-viscoacoustic TTI wave equation Attenuation anisotropy Seismic modeling Low-rank decomposition method