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'PEOPLE'S EDUCATOR'MAKES TEACHING LIFELONG MISSION

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Women of China 2021年第9期 10-13页

作者： xie lin 无不详 Shanghai Women's Federation Photomail

Yu Yi,Honorary President of Shanghai Yangpu Senior High School,was among the first generation of Chinese-language teachers in the country after the founding of the People's Republic of China in ***,recipient of the 2019 People's Educator award,has spent more than six decades teaching the Chinese *** adhering to her philosophy on teaching,she has made outstanding contributions during the reform and development of basic education across the *** bas received several honorary titles,including National March 8th Red-Banner Holder,National Advanced Worker and Most Beautiful Striver.

关键词：人民教育家名誉校长基础教育改革于漪上讲台国家荣誉称号语文教师教育理念

谢林教授从“痰瘀滞络”学说论治椎动脉型颈椎病的临床疗效

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内蒙古中医药 2024年第1期43卷 85-89页

作者：张翔谢林昆山市中医医院骨伤科江苏昆山215300 江苏省中西医结合医院骨伤科江苏南京210028

目的:观察葛泽定眩汤治疗椎动脉型颈椎病的临床疗效。方法:将符合纳入标准的100例患者,随机分成对照组和治疗组,分别给予盐酸氟桂利嗪胶囊及葛泽定眩汤治疗,并通过观察颈性眩晕症状与采集功能评估量表(ESCV)头晕问卷调查表(DHI)疼痛视... 详细信息

目的:观察葛泽定眩汤治疗椎动脉型颈椎病的临床疗效。方法:将符合纳入标准的100例患者,随机分成对照组和治疗组,分别给予盐酸氟桂利嗪胶囊及葛泽定眩汤治疗,并通过观察颈性眩晕症状与采集功能评估量表(ESCV)头晕问卷调查表(DHI)疼痛视觉模拟评分(VAS评分)及中药新药临床疗效评定标准加以评判。结果:与治疗前相比,治疗2周后及治疗后3月,两组ESVC、DHI、VAS数值均明显优于治疗前。两组对比发现,在治疗2周后及治疗后3月,葛泽定眩汤组疗效均明显优于盐酸氟桂利嗪胶囊组。葛泽定眩汤组临床治疗有效率达97.83%(45/46),高于盐酸氟桂利嗪胶囊的临床治疗有效率83.67%(41/49)。结论:从“痰瘀滞络”学说拟定的葛泽定眩汤治疗椎动脉型颈椎病有较好的临床疗效,特色突出,值得推广。

关键词：椎动脉型颈椎病葛泽定眩汤中医药疗效观察

Delivery of pOXR1 through an injectable liposomal nanoparticle enhances spinal cord injury regeneration by alleviating oxidative stress

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Bioactive Materials 2021年第10期6卷 3177-3191页

作者： Jing Zhang Yao Li Jun Xiong Helin Xu Guanghen Xiang Mingqiao Fan Kailiang Zhou Yutian lin Xiangxiang Chen lin xie Hongyu Zhang Jian Wang Jian Xiao Department of Hand Surgery and Peripheral Neurosurgery The First Affiliated Hospital and School of Pharmaceutical SciencesWenzhou Medical UniversityWenzhou325025China Department of Orthopaedics The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical UniversityWenzhou325000China

Oxidation resistance 1(OXR1)is regarded as a critical regulator of cellular homeostasis in response to oxidative ***,the role of OXR1 in the neuronal response to spinal cord injury(SCI)remains *** the other hand,gene therapy for SCI has shown limited success to date due in part to the poor utility of conventional gene *** this study,we evaluated the function of OXR1 in SCI and developed an available carrier for delivering the OXR1 plasmid(pOXR1).We found that OXR1 expression is remarkably increased after SCI and that this regulation is protective after ***,we assembled cationic nanoparticles with vitamin E succinate-graftedε-polylysine(VES-g-PLL)(Nps).The pOXR1 was precompressed with Nps and then encapsulated into cationic *** particle size of pOXR1 was compressed to 58 nm,which suggests that pOXR1 can be encapsulated inside liposomes with high encapsulation efficiency and stability to enhance the transfection *** agarose gel results indicated that Nps-pOXR1-Lip eliminated the degradation of DNA by DNase I and maintained its activity,and the cytotoxicity results indicated that pOXR1 was successfully transported into cells and exhibited lower ***,Nps-pOXR1-Lip promoted functional recovery by alleviating neuronal apoptosis,attenuating oxidative stress and inhibiting ***,our study provides considerable evidence that OXR1 is a beneficial factor in resistance to SCI and that Nps-Lip-pOXR1 exerts therapeutic effects in acute traumatic SCI.

关键词： Gene therapy OXR1 DNA condensed agent Spinal cord injury Oxidative stress

Crystal Structure and Bovine Serum Albumin Binding Studies of Methyl 4-(2,4-Dichlorophenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate

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Chinese Journal of Structural Chemistry 2019年第2期38卷 242-250,166页

作者： PENG Hua-Nan xie Jia-lin CHEN Xi ZHENG Jie XU He-Tao LIU Hua-Hua College of Chemistry and Environmental Sciences Shangrao Normal University

The title compound, methyl 4-(2,4-dichlorophenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate(C_(20) H_(21)Cl_2NO_3, 1) was synthesized and the crystal structure was —determined by single-crystal X-ray diffraction. It crystallizes in tetragonal system, space group P421 c with a = 16.076(3), b = 16.076(3), c = 14.750(2) ?, V = 3811.8(14) ?3, Z = 8, R = 0.0377 and wR = 0.0845. The interactions between compound 1 and bovine serum albumin(BSA) were investigated using fluorescence spectroscopy. The results revealed that compound 1 can effectively quench the intrinsic fluorescence of BSA by static quenching mechanism. The thermodynamic parameters revealed that the action forces between compound 1 and BSA were mainly van der Waals forces and hydrogen bonds. According to F?rster's non-radioactive energy transfer theory, the binding distance between compound 1 and BSA had been determined. Furthermore, the synchronous fluorescence showed that compound 1 has few effects on the microenvironment and conformation of BSA in the binding process.

关键词： 1,4-dihydropyridine crystal structure bovine serum albumin fluorescence quenching

Risk factors for flat anterior chamber after glaucoma filtration surgery

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International Journal of Ophthalmology(English edition) 2018年第8期11卷 1322-1329页

作者： Xiang-Ji Zi Richard Filek Xiang-Ge He Wei Wang Hong Liu Lian He Yu-Rong Tang lin xie Department of Ophthalmology the Third Affiliated HospitalChongqing Medical University Chongqing 400016 China Department of Ophthalmology Institute of Surgery ResearchDaping Hospital Third Military Medical UniversityChongqing 400042 China Department of Pathology and Laboratory Medicine Western University London ON N6A 3K7 Canada Ivey Eye Institute St. Joseph's Hospital London ON N6A4V2 Canada Chongqing Aier Eye Hospital of Aier Eye Hospital Group Chongqing 400020 China Department of Ophthalmology People's Hospital Zhongshan Branch Chongqing 400013 China

AIM： To investigate the incidence rate and risk factors for grade Ⅲ flat anterior chamber（FAC） after glaucoma filtration surgery based on 5-year ***： Patients who underwent glaucoma filtration surgery in Daping hospital from January 2009 to December 2013 were enrolled in this retrospective study. The incidence of grade Ⅲ FAC following glaucoma filtration surgery was determined. Regression analysis was performed to investigate the influence of glaucoma type, surgical approach, age, and preoperative intraocular pressure（IOP） on the risk of postoperative ***： A total of 2179 eyes receiving anti-glaucoma surgery were included. Ninety-one eyes suffered from postoperative FAC, with an overall incidence rate of 4.18%. Of 471 eyes with primary open angle glaucoma（POAG）, grade Ⅲ FAC occurred in only 3 eyes（0.64%）. Primary angleclosure glaucoma（PACG） was diagnosed in 1076 eyes, 39（3.62%） of which developed grade Ⅲ FAC, including 12 eyes（12/300, 4%） with acute PACG（aP ACG） and 27 eyes（27/776, 3.48%） with chronic PACG（c PACG）. Six of 259 eyes（2.32%） with secondary glaucoma, 28 of 186 eyes（15.05%） with neovasular glaucoma, 1 of 66 eyes（1.52%） with congenital glaucoma, and 14 of 115 eyes（12.17%） with remnant glaucoma suffered from grade Ⅲ FAC. Of 6 eyes with mixed glaucoma, none developed grade Ⅲ FAC after surgery. When stratified by surgical approach, 24 of 766 eyes（3.13%） undergoing trabeculectomy, 21 of 924 eyes（2.27%） treated by trabeculectomy plus mitomycin C（MMC）, 18 of 109 eyes（16.51%） undergoing Ahmed glaucoma valve implantation, 23 of 201 eyes（11.44%） managed by Ahmed implantation plus MMC, and 5 of 133 eyes（3.76%） treated by Ahmed implantation plus lens extraction or vitrectomy developed grade Ⅲ FAC. Logistic regression analysis revealed that factors including neovasular glaucoma, remnant glaucoma, glaucoma valve implantation, glaucoma valve implantation＋MMC, glaucoma valve implantation＋vitrectomy, age〉60 y, and IOP at admission 〉50 mm Hg were significa

关键词： glaucoma filtration surgery grade IIIflat anterior chamber trabeculectomy glaucoma valveimplantation mitomycin C

Baoshan launches project of special spinning industrial base

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China Textile 2016年第12期 48-49页

作者： xie lin Shen Da

Recently, textile enterprises set their sights of indus- trial transfer on Baoshan in an endless stream. Tianjin Textile Group （Holding） Co., Ltd. has singed a program with 125 thousand spindles of spinning and 50 million meters of weaving, and now engages in the next phase of investment plan. Dezhou Hengfeng Group has de- cided to increase to 500 thousand spindles, based on the 300 thousand spindles. There are some other enterprises coming in a throng, in order to understand the usage of equipment, listen to the improvement suggestions, and lay the foundation for the next step.

关键词：英语阅读理解中国纺织业

Headmistress Committed to Primary School Education for Decades

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Women of China 2022年第1期 14-17页

作者： xie lin 不详

"Luwan No.1 Central Primary School plays a leading rold in shaping the learning environment in the 21st century,and it incorporates sciences and new technologies with students'education on social cognitive skills and sentimental values,"Andreas Schleicher,Director for the Directorate of Education and Skills at the Organization for Economic Cooperation and Development(OECD),wrote in a book,World Class:How to Build a 2lst-century School *** once visited the school,in the Huangpu District of Shanghai,where he met the headmistress,Wu *** has worked in education,and she has made endless efforts in the pursuit of her education dream,for the past 28 years.

关键词：中心小学经济合作与发展组织 PISA 上海市黄浦区基础教育新型科技引领作用静待花开

Measurement of ^(232)Th(n,2n)^(231)Th reaction cross-sections at neutron energies of 14.1 MeV and 14.8 MeV using neutron activation method

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Nuclear Science and Techniques 2015年第6期26卷 100-103页

作者：兰长林解保林张凯彭猛方开洪 School of Nuclear Science and Technology Lanzhou University Department of Nuclear Physics China Institute of Atomic Energy

In this study, the activation cross-sections were measured for ^(232)Th(n,2n)^(231)Th reactions at neutron energies of 14.1 and 14.8 MeV, which were produced by a neutron generator through a T(d,n)~4He reaction. Induced gamma-ray activities were measured using a low background gamma ray spectrometer equipped with a high resolution HPGe detector. In the cross-section calculations, corrections were made regarding the effects of gamma-ray attenuation, dead-time, fluctuation of the neutron flux, and low energy neutrons. The measured cross-sections were compared with the literature data, evaluation data(ENDF-B/VII.1, JENDL-4.0 and CENDL-3.1), and the results of the model calculation(TALYS1.6).

关键词：中子能量反应截面 MeV 中子活化法测量 HPGe探测器中子发生器高分辨率

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土地利用生态安全格局研究进展

生态学报 2008年第12期28卷 6305-6311页

作者：谢花林江西财经大学资源与环境管理学院江西南昌330032 中国科学院地理科学与资源研究所北京100101

土地生态安全格局研究不仅可以为有效解决水土流失、土壤退化等区域生态安全问题提供新的思路,而且对提高区域土地生态系统的安全性和可持续性具有重要的现实意义。从土地利用生态安全评价、面向生态的土地利用格局和土地生态安全格局... 详细信息

土地生态安全格局研究不仅可以为有效解决水土流失、土壤退化等区域生态安全问题提供新的思路,而且对提高区域土地生态系统的安全性和可持续性具有重要的现实意义。从土地利用生态安全评价、面向生态的土地利用格局和土地生态安全格局构建方法3个方面,综述了土地利用生态安全格局的研究现状和最新进展,并对今后的研究方向进行了展望,以促进土地生态安全格局研究的继续深入开展。提出近期的研究重点主要包括:(1)面向生态安全格局设计的生态安全评价方法与模型;(2)不同类型生态脆弱地区的土地生态安全格局;(3)土地生态安全格局的空间显示模型;(4)区域土地生态安全格局情景模拟。

关键词：生态安全格局土地利用空间显示模型