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Nonlinear uncertainty impact of geometric variations on aerodynamic performance of low-pressure turbine blades with ultra-high loading under extreme operational conditions

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Chinese Journal of Aeronautics 2024年第5期37卷 281-300页

作者： xiaojing wang Zhengping ZOU Chao FU Pengcheng DU School of Energy and Power Engineering Beihang UniversityBeijing 100191China National Key Laboratory of Science and Technology on Aero-Engine Aero-Thermodynamics Beihang UniversityBeijing 100191China Research Institute of Aero-Engine Beihang UniversityBeijing 100191China

Uncertainty impact of random geometric variations on the aerodynamic performance of low-pressure turbine blades is considerable,which is further amplified by the current ultra-high-lift design trend for weight ***,this uncertainty impact on ultra-highly loaded blades under extreme operational conditions near the margins with potential large-scale open separation is focused on in this *** is demonstrated that this impact is significant,unfavourable,and nonlinear,which is clearly severer under extreme *** addition to the overall attenuation and notable scattering of specific performance,the operational margins with open separation are also notably scattered with great risk of significant *** scattering and nonlinearity are dominated by the variations in leading-edge *** thinning of leading edge triggers local transition,enhancing downstream friction and reducing resistance to open separation,which is further exacerbated by operational ***,the opposite thickening yields less benefit,implying *** unfavourable impact highlights the need for robust aerodynamic design,where both a safer operational condition and a more robust blade are indispensable,i.e.,a compromise among performance,weight,and *** the necessary limitation of loading levels,a mid-loaded design is recommended to reduce adverse pressure gradients in both the leading edge and rear region of the suction side,which helps to decrease the susceptibility of the transition and open separation to random *** improvements can also be achieved by appropriately thickening the leading edge.

关键词： Ultra-highly loaded turbine blade Geometric variations Uncertainty analysis Operational margins Robust aerodynamic design Nonlinearity

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Microstructure and Shear Properties Evolution of Minor Fe-Doped SAC/Cu Substrate Solder Joint under Isothermal Aging

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Acta Metallurgica Sinica(English Letters) 2024年第7期37卷 1279-1290页

作者： Quanzhen Li Chengming Li xiaojing wang Shanshan Cai Jubo Peng Shujin Chen Jiajun wang Xiaohong Yuan Jiangsu University of Science and Technology Zhenjiang212003China R&D Center Yunnan Tin Group(Holding)Co.LtdKunming650000China The 58 Research Institute of China Electronics Technology Group CorporationWuxi214100China Yunnan Precious Metals Lab Sino-Platinum Metals Co.LtdKunming650156China

Different amounts of Fe(0.005,0.01,0.03,0.05,and 0.07 wt%)were added to SAC305 to study the shear behavior damage of Fe-doped SAC solder joints under thermal loading(170℃,holding time of 0,250,500,and 750 h).The results show that during isothermal aging at 170℃,the average shear force of all solder joints decreases with increasing aging time,while the average fracture energy first increases and then decreases,reaching a maximum at 500 *** Fe doping could both increase shear forces and related fracture energy,with the optimum Fe doping amount being 0.03 wt%within the entire aging *** is because the doping Fe reduces the undercooling of the SAC305 alloy,resulting in the microstructure refining of solder *** in turn causes the microstructure changing from network structure(SAC305 joint:eutectic network+β-Sn)to a single matrix structure(0.03Fe-doped SAC305 joint:β-Sn matrix+small compound particles).Specifically,Fe atoms can replace some Cu in Cu_(6)Sn_(5)(both inside the solder joint and at the interface),and then form(Cu,Fe)_(6)Sn_(5) compounds,resulting in an increase in the elastic modulus and nanohardness of the ***,the growth of Cu_(6)Sn_(5) and Cu_(3)Sn intermetallic compounds(IMC)layer are inhibited by Fe doping even after the aging time prolonging,and Fe aggregates near the interface compound to form FeSn_(2).This study is of great significance for controlling the growth of interfacial compounds,stabilizing the microstructures,and providing strengthening strategy for solder joint alloy design.

关键词： SAC305 solder Fe doping Shear mechanical behavior Isothermal aging Interfacial intermetallic compounds(IMC)

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Electrochemical Hydrogen Charging on Corrosion Behavior of Ti-6Al-4V Alloy in Artificial Seawater

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Chinese Journal of Mechanical Engineering 2024年第1期37卷 296-308页

作者： Yanxin Qiao Yue Qin Huiling Zhou Lanlan Yang xiaojing wang Zhengbin wang Zhenguang Liu Jiasheng Zou School of Materials Science and Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China Yangzhou Changelight Co. LtdYangzhou 225012China CAS Key Laboratory of Nuclear Materials and Safety Assessment Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China

This study employs advanced electrochemical and surface characterization techniques to investigate the impact of electrochemical hydrogen charging on the corrosion behavior and surface film of the Ti-6Al-4V *** findings revealed the formation ofγ-TiH andδ-TiH_(2) hydrides in the alloy after hydrogen *** hydrogen charging resulted in more significant degradation of the alloy microstructure,leading to deteriorated protectiveness of the surface *** trend was further confirmed by the electrochemical measurements,which showed that the corrosion resistance of the alloy progressively worsened as the hydrogen charging time was ***,this work provides valuable insights into the mechanisms underlying the corrosion of Ti-6Al-4V alloy under hydrogen charging conditions.

关键词： Ti-6Al-4V alloy Hydrogen charging Electrochemical corrosion Passive film

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Meiotic nuclear divisions 1 suppresses the proliferation and invasion of pancreatic cancer cells via regulating H2A.X variant histone

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BIOCELL 2024年第1期48卷 111-122页

作者： DONGQIN wang YAN SHI ZHIQIANG wang JING ZHANG LUYAO wang HONGYU MA SHUHUA SHI XIAOFU LIAN HUA HUANG xiaojing wang CHAOQUN LIAN Anhui Province Key Laboratory of Clinical and Preclinical Research in Respiratory Disease Molecular Diagnosis CenterThe Department of Pulmonary Critical Care MedicineFirst Affiliated Hospital of Bengbu Medical CollegeBengbu233030China Department of Genetics School of Life SciencesBengbu Medical CollegeBengbu233000China Department of Clinical Medicine Bengbu Medical CollegeBengbu233030China Research Center of Clinical Laboratory Science Bengbu Medical CollegeBengbu233030China

Introduction:Among all malignant tumors of the digestive system,pancreatic carcinoma exhibits the highest mortality ***,prevention and effective treatment are urgent issues that need to be ***:The study focused on meiotic nuclear divisions 1(MND1),integrating data from the Gene Expression Profiling Interactive Analysis(GEPIA)database with prognostic survival ***,experiments at cellular level were employed to demonstrate the effect of MND1 on the proliferation and migration of *** small-molecule inhibitor of MND1 was used to suppress the migration of PC cells by knocking down MND1 using small interfering RNA(siRNA)in Patu-8988 and Panc1 cell ***:The results of Cell Counting Kit-8 indicated that the suppression of MND1 resulted in a decrease in cell *** healing and Transwell assays revealed that MND1 knockdown reduced cell migration and *** cytometry revealed that inhibiting MND1 hindered the cell ***,MND1 could stimulate the proliferation,migration,and invasion of Patu-8988 and Panc1 cells by increasing the expression of ***,MND1 had a positive effect on H2AFX expression in PC *** MND1 expression suggests the low overall survival rate of individuals diagnosed with ***:These findings suggest that MND1 has the potential to be a gene with the ability to accurately diagnose and treat PC.

关键词： Pancreatic carcinoma MND1 H2AFX Cell cycle

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Atmospheric nitrogen deposition affects forest plant and soil system carbon:nitrogen:phosphorus stoichiometric flexibility:A meta-analysis

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Forest Ecosystems 2024年第3期11卷 307-317页

作者： Xiyan Jiang xiaojing wang Yaqi Qiao Yi Cao Yan Jiao An Yang Mengzhou Liu Lei Ma Mengya Song Shenglei Fu Key Laboratory of Geospatial Technology for the Middle and Lower Yellow River Regions College of Geography and Environmental ScienceHenan UniversityKaifeng475004China Henan Key Laboratory of Integrated Air Pollution Control and Ecological Security College of Geography and Environmental ScienceHenan UniversityKaifeng475004China Henan Dabieshan National Field Observation and Research Station of Forest Ecosystem Henan UniversityZhengzhou450046China

Background:Nitrogen(N)deposition affects forest stoichiometric flexibility through changing soil nutrient availability to influence plant ***,the effect of N deposition on the flexibility of carbon(C),N,and phosphorus(P)in forest plant-soil-microbe systems remains ***:We conducted a meta-analysis based on 751 pairs of observations to evaluate the responses of plant,soil and microbial biomass C,N and P nutrients and stoichiometry to N addition in different N intensity(050,50–100,>100 kg·ha^(-1)·year^(-1)of N),duration(0–5,>5 year),method(understory,canopy),and matter(ammonium N,nitrate N,organic N,mixed N).Results:N addition significantly increased plant N:P(leaf:14.98%,root:13.29%),plant C:P(leaf:6.8%,root:25.44%),soil N:P(13.94%),soil C:P(10.86%),microbial biomass N:P(23.58%),microbial biomass C:P(12.62%),but reduced plant C:N(leaf:6.49%,root:9.02%).Furthermore,plant C:N:P stoichiometry changed significantly under short-term N inputs,while soil and microorganisms changed drastically under high N *** N addition primarily affected plant C:N:P stoichiometry through altering plant N content,while understory N inputs altered more by influencing soil C and P *** N significantly influenced plant and soil C:N and C:P,while ammonia N changed plant N:*** C:P and soil C:N were strongly correlated with mean annual precipitation(MAT),and the C:N:P stoichiometric flexibility in soil and plant under N addition connected with soil ***,N addition decoupled the correlations between soil microorganisms and the ***:N addition significantly increased the C:P and N:P in soil,plant,and microbial biomass,reducing plant C:N,and aggravated forest P ***,these impacts were contingent on climate types,soil layers,and N input *** findings enhance our comprehension of the plant-soil system nutrient cycling mechanisms in forest ecosystems and plant strategy responses to N deposition.

关键词： C:N:P stoichiometry Meta-analysis Forest ecosystem Nitrogen addition form Nutrient cycles

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Straw return increases crop production by improving soil organic carbon sequestration and soil aggregation in a long-term wheat-cotton cropping system

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Journal of Integrative Agriculture 2024年第2期23卷 669-679页

作者： Changqin Yang xiaojing wang Jianan Li Guowei Zhang Hongmei Shu Wei Hu Huanyong Han Ruixian Liu Zichun Guo Institute of Industrial Crops Jiangsu Academy of Agricultural Sciences/Key Laboratory of Cotton and RapeseedMinistry of Agriculture and Rural AffairsNanjing 210014China College of Life Sciences and Food Engineering Huaiyin Institute of TechnologyHuai’an 223003China College of Agriculture Nanjing Agricultural UniversityNanjing 210095China Cotton Research Institute Xinjiang Academy of Agricultural and Reclamation ScienceShihezi 832000China Institute of Soil Science Chinese Academy of Sciences/State Key Laboratory of Soil and Sustainable AgricultureNanjing 210008China

Straw return is a promising strategy for managing soil organic carbon(SOC)and improving yield ***,the optimal straw return strategy for sustainable crop production in the wheat(Triticum aestivum L.)-cotton(Gossypium hirsutum L.)cropping system remains *** objective of this study was to quantify the long-term(10 years)impact of carbon(C)input on SOC sequestration,soil aggregation and crop yields in a wheat-cotton cropping system in the Yangtze River Valley,*** treatments were arranged with a single-factor randomized design as follows:no straw return(Control),return of wheat straw only(Wt),return of cotton straw only(Ct),return of 50%wheat and 50%cotton straw(Wh-Ch)and return of 100%wheat and 100%cotton straw(Wt-Ct).In comparison to the Control,the SOC content increased by 8.4 to 20.2%under straw return.A significant linear positive correlation between SOC sequestration and C input(1.42-7.19 Mg ha^(−1)yr^(−1))(P2 and 1-2 mm at the 0-20 cm soil depth were also significantly elevated under straw return,with the greatest increase of the aggregate stability in the Wt-Ct treatment(28.1%).The average wheat yields increased by 12.4-36.0%and cotton yields increased by 29.4-73.7%,and significantly linear positive correlations were also detected between C input and the yields of wheat and *** average sustainable yield index(SYI)reached a maximum value of 0.69 when the C input was 7.08 Mg ha^(−1)yr^(−1),which was close to the maximum value(SYI of 0.69,C input of 7.19 Mg ha^(−1)yr^(-1))in the Wt-Ct ***,the return of both wheat and cotton straw was the best strategy for improving SOC sequestration,soil aggregation,yields and their sustainability in the wheat-cotton rotation system.

关键词： straw return crop yields SOC soil aggregates wheat-cotton cropping system

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Chromosomal-level genome and metabolome analyses of highly heterozygous allohexaploid Dendrocalamus brandisii elucidate shoot quality and developmental characteristics

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Journal of Integrative Plant Biology 2024年第6期66卷 1087-1105页

作者： Jutang Jiang Zeyu Zhang Yucong Bai xiaojing wang Yuping Dou Ruiman Geng Chongyang Wu Hangxiao Zhang Cunfu Lu Lianfeng Gu Jian Gao Key Laboratory of National Forestry and Grassland Administration Beijing for Bamboo&Rattan Science and TechnologyInstitute of Gene Science and Industrialization for Bamboo and Rattan ResourcesInternational Center for Bamboo and RattanBeijing 100102China College of Forestry Basic Forestry and Proteomics Research CenterFujian Agriculture and Forestry UniversityFuzhou 350002China School of Life Science Peking UniversityBeijing 100871China College of Biological Sciences and Biotechnology Beijing Forestry UniversityBeijing 100083China

Dendrocalamus brandisii(Munro)Kurz is a sympodial bamboo species with inimitable taste and flavorful *** rapid growth and use as high-quality material make this bamboo species highly valued for both food processing and wood ***,genome information for *** is lacking,primarily due to its polyploidy and large genome ***,we assembled a high-quality genome for hexaploid ***,which comprises 70chromosomes with a total size of 2,756 Mb,using long-read Hi Fi ***,we accurately separated the genome into its three constituent *** used Oxford Nanopore Technologies long reads to construct a transcriptomic dataset covering 15 tissues for gene annotation to complement our genome assembly,revealing differential gene expression and post-transcriptional *** integrating metabolome analysis,we unveiled that well-balanced lignin formation,as well as abundant flavonoid and fructose contents,contribute to the superior quality of *** *** genomic,transcriptomic,and metabolomic datasets provided a solid foundation for enhancing bamboo shoot quality and developing efficient gene-editing *** study should facilitate research on *** and enhance its use as a food source and wood material by providing crucial genomic resources.

关键词： bamboo shoots Dendrocalamus brandisii(Munro)Kurz flavonoid genome lignin

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Paeoniflorin ameliorates chronic colitis via the DR3 signaling pathway in group 3 innate lymphoid cells

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Journal of Pharmaceutical Analysis 2024年第6期14卷 889-901页

作者： Shaowei Huang Xueqian Xie Bo Xu Zengfeng Pan Junjie Liang Meiling Zhang Simin Pan xiaojing wang Meng Zhao Qing wang Jinyan Chen Yanyang Li Lian Zhou Xia Luo School of Pharmaceutical Sciences Guangzhou University of Chinese Medicine510006China School of Basic Medicine Guangzhou University of Chinese Medicine510006China First Clinical Medical College Guangzhou University of Chinese Medicine510000China

Inhibiting the death receptor 3(DR3)signaling pathway in group 3 innate lymphoid cells(ILC3s)presents a promising approach for promoting mucosal repair in individuals with ulcerative colitis(UC).Paeoniflorin,a prominent component of Paeonia lactiflora Pall.,has demonstrated the ability to restore barrier function in UC mice,but the precise mechanism remains *** this study,we aimed to delve into whether paeoniflorin may promote intestinal mucosal repair in chronic colitis by inhibiting DR3 signaling in ILC3s.C57BL/6 mice were subjected to random allocation into 7 distinct groups,namely the control group,the 2%dextran sodium sulfate(DSS)group,the paeoniflorin groups(25,50,and 100 mg/kg),the anti-tumor necrosis factor-like ligand 1A(anti-TL1A)antibody group,and the IgG *** detected the expression of DR3 signaling pathway proteins and the proportion of ILC3s in the mouse colon using Western blot and flow cytometry,***,DR3-overexpressing MNK-3 cells and 2%DSS-induced Rag1^(-/-)mice were used for *** results showed that paeoniflorin alleviated DSS-induced chronic colitis and repaired the intestinal mucosal ***,paeoniflorin inhibited the DR3 signaling pathway in ILC3s and regulated the content of cytokines(interleukin-17A,granulocyte-macrophage colony stimulating factor,and interleukin-22).Alternatively,paeoniflorin directly inhibited the DR3 signaling pathway in ILC3s to repair mucosal damage independently of the adaptive immune *** additionally confirmed that paeoniflorin-conditioned medium(CM)restored the expression of tight junctions in Caco-2 cells via *** conclusion,paeoniflorin ameliorates chronic colitis by enhancing the intestinal barrier in an ILC3-dependent manner,and its mechanism is associated with the inhibition of the DR3 signaling pathway.

关键词： Paeoniflorin Ulcerative colitis Intestinal mucosal barrier DR3 signaling pathway Group 3 innate lymphoid cells

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Receding Horizon Control-Based Stabilization of Singular Stochastic Systems with State Delay

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Journal of Shanghai Jiaotong university(Science) 2024年第3期29卷 436-449页

作者：王晓静刘晓华高荣 College of Engineering Yantai Nanshan UniversityYantai 265706ShandongChina School of Mathematics and Statistics Science Ludong UniversityYantai 264025ShandongChina

For a class of discrete-time singular stochastic systems with multi-state delay,the stabilization problem of receding horizon control(RHC)is *** to the difficulty in solving the proposed optimization problem,the RHC stabilization for such systems has not been *** adopting the forward and backward equation technique,the optimization problem is solved completely.A sufficient and necessary condition for the optimization controller to have a unique solution is given when the regularization and pulse-free conditions are *** on this controller,an RHC stabilization condition is derived,which is in the form of linear matrix *** is proved that the singular stochastic system with multi-state delay is stable in the mean-square sense under appropriate assumptions when the terminal weighting matrix satisfies the given *** examples show that the proposed RHC method is effective in stabilizing singular stochastic systems with multi-state delay.

关键词： receding horizon control(RHC) singular stochastic system state delay stabilization

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Transcriptomic Analysis of Wheat Reveals Possible Resistance Mechanism Mediated by Yr10 to Stripe Rust

Transcriptomic Analysis of Wheat Reveals Possible Resistance...

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中国植物病理学会2024年学术年会

作者： ZHANG Gaohua KANG Zhensheng wang xiaojing State Key Laboratory of Crop Stress Biology for Arid Areas and College of Plant Protection Northwest A&F University State Key Laboratory of Crop Stress Biology for Arid Areas and College of Life Sciences Northwest A&F University

Stripe rust,caused by Puccinia striiformis ***(Pst),is a catastrophic disease that threatens global wheat ***10 is a race-specific all-stage disease resistance gene in ***,the resistance mechanism of Yr10 is poorly ***,to elucidate the potential molecular mechanism mediated by Yr10,transcriptomic sequencing was performed at 0,18,and 48 h post-inoculation(hpi) of compatible wheat Avocet S(AvS) and incompatible near-isogenic line(NIL) AvS+Yr10 inoculated with Pst race ***,227,208,and 4050 differentially expressed genes(DEGs) were identified at 0,18,and 48 hpi between incompatible and compatible *** response of Yr10 to stripe rust involved various processes and activities,as indicated by the results of Gene Ontology(GO) enrichment analysis and Kyoto Encyclopedia of Genes and Genomes(KEGG) pathway ***,the response included photosynthesis,defense response to fungus,metabolic processes related to salicylic acid(SA) and jasmonic acid(JA),and activities related to reactive oxygen species(ROS).Ten candidate genes were selected for qRT-PCR verification and the results showed that the transcriptomic data was *** the functional analysis of candidate genes by the virus-inducted gene silencing(VIGS) system,it was found that the gene TaHPPD(4-hydroxyphenylpyruvate dioxygenase) negatively regulated the resistance of wheat to stripe rust by affecting SA signaling,pathogenesis-related(PR) gene expression,and ROS *** study provides insight into Yr10-mediated resistance in wheat.

关键词： Transcriptome Yr10 Virus-induced gene silencing system (VIGS) system 4-hydroxyphenylpyruvate dioxygenase HPPD

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