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Wide Operational Range Processor Power Delivery Design for Both Super-Threshold Voltage and Near-Threshold Voltage Computing

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Journal of Computer Science & Technology 2016年第2期31卷 253-266页

作者： Xin He Gui-Hai Yan Yin-He Han xiao-wei li State Key Laboratory of Computer Architecture Institute of Computing Technology Chinese Academy of Sciences Beijing 100190 China University of Chinese Academy of Sciences Beijing 100049 China

The load power range of modern processors is greatly enlarged because many advanced power management techniques are employed, such as dynamic voltage frequency scaling, Turbo Boosting, and near-threshold voltage （NTV） technologies. However, because the efficiency of power delivery varies greatly with different load conditions, conventional power delivery designs cannot maintain high efficiency over the entire voltage spectrum, and the gained power saving may be offset by power loss in power delivery. We propose SuperRange, a wide operational range power delivery unit. SuperRange complements the power delivery capability of on-chip voltage regulator and off-chip voltage regulator. On top of SuperRange, we analyze its power conversion characteristics and propose a voltage regulator （VR） aware power management algorithm. Moreover, as more and more cores have been integrated on a singe chip, multiple SuperRange units can serve as basic building blocks to build, in a highly scalable way, more powerful power delivery subsystem with larger power capacity. Experimental results show SuperRange unit offers lx and 1.3x higher power conversion efficiency （PCE） than other two conventional power delivery schemes at NTV region and exhibits an average 70% PCE over entire operational range. It also exhibits superior resilience to power-constrained systems.

关键词： voltage regulator power delivery near-threshold computing multicore processor

Solidification crack characteristics and sensitivity of peritectic steel

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Journal of Iron and Steel Research International 2024年第7期31卷 1668-1679页

作者： Ya-qiang li Jian-hua liu Zi-ming Wang Ying-ying li Yang He xiao-wei li Department of Automotive Engineering Hebei Vocational University of Technology and EngineeringXingtai 054000HebeiChina Hebei Special Vehicle Modification Technology Innovation Center Hebei Vocational University of Technology and EngineeringXingtai 054000HebeiChina Institute of Engineering Technology University of Science and Technology BeijingBeijing 100083China School of Petroleum and Natural Gas Engineering Changzhou UniversityChangzhou 213164JiangsuChina

The characteristics and sensitivity of solidification cracks in peritectic steels were investigated using directional solidifi-cation *** cracks were observed in both hypoperitectic steels(12CrlMoV,15CrMo)and hyper-peritectic steel(20CrMo)during solidification at growth velocities of 15,50,and 80 pm/*** the dendritic boundaries,sulphide precipitates were found,promoting crack *** on the statistical analysis of interdendritic cracks in peritectic steels,the area ratio(RA)of interdendritic cracks in a directional solidification structure was proposed to evaluate the crack sensitivity of peritectic ***,the crack sensitivities of peritectic steels(12CrlMoV,15CrMo,and 20CrMo)were tested,evaluated,and compared with the surface crack rates of three types of steels produced from a steel *** results demonstrated that RA was in good agreement with that of the steel plant,and the crack sensitivity of 12CrlMoV steel was the strongest,followed by that of 15CrMo and 20CrMo ***,RA can be used to evaluate the crack sensitivity of peritectic steel.

关键词： Peritectic steel-Directional solidification Growth velocity Dendritic structure Solidification crack Crack sensitivity

High-Temperature Stability of Mg-1Al-12Y Alloy Containing LPSO Phase and Mechanism of Its Portevin-Le Chatelier(PLC)Effect

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Acta Metallurgica Sinica(English Letters) 2024年第6期37卷 982-998页

作者： Qian-Long Ren Shuai Yuan Shi-Yu Luan Jin-Hui Wang xiao-wei li xiao-Yu liu Qinghai Provincial Key Laboratory of New light Alloys Qinghai Provincial Engineering Research Center of High Performance Light Metal Alloys and FormingQinghai UniversityXining810016China School of Materials Science and Engineering Shenyang University of TechnologyShenyang110870China

In this study,the high-temperature stability and the generation mechanism of the Portevin-Le Chatelier(PLC)effect in solid-solution Mg-1Al-12Y alloy with different heat treatment processes were investigated by adjusting the content of long-period stacking ordered(LPSO)*** was found that the content of LPSO phases in the alloys differed the most after heat treatment at 530℃for 16 h and 24 h,with values of 13.56%and 3.93%***,high-temperature tensile experiments were conducted on these two alloys at temperatures of 150℃,200℃,250℃,and 300℃.The results showed that both alloys exhibited the PLC effect at temperatures ranging from 150 to 250℃.However,at a temperature 300℃,only the alloy with a greater concentration of LPSO phases exhibited the PLC effect,whereas the alloy with a lower proportion of LPSO phases did not exhibit this ***,both alloys exhibited remarkable high-temperature stability,with the alloy containing a greater percentage of LPSO phases also demonstrating superior *** underlying mechanism for this phenomenon lies in the exceptional high-temperature stability exhibited by the second phase within the ***,the LPSO phase effectively obstructs the movement of dislocations,and it also undergoing kinking to facilitate plastic deformation of the *** results indicate that the PLC effect can be suppressed by reducing dislocation pile-up at grain boundaries,which leads to a decrease in alloy plasticity but an increase in *** presence of the PLC effect in the WA121 alloy is attributed to the abundant dispersed second phase within the alloy,which initially hinders the movement of dislocations,leading to an increase in stress,and subsequently releases the dislocations,allowing them to continue their movement and thereby reducing in stress.

关键词： Magnesium alloy Long-period stacking ordered(LPSO)phase Portevin-Le Chatelier effect High temperature

Microstructure evolution and thixoforming behavior of 7075 aluminum alloy in the semi-solid state prepared by RAP method

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International Journal of Minerals,Metallurgy and Materials 2016年第12期23卷 1404-1415页

作者： Jin-long Fu Kai-kun Wang xiao-wei li Hai-kuan Zhang School of Materials Science and Engineering University of Science and Technology Beijing Tianjin Zhonglian Precision Casting Co. Ltd.

The effects of isothermal treatments on the microstructural evolution and coarsening rate of semi-solid 7075 aluminum alloy produced via the recrystallization and partial remelting （RAP） process were investigated. Samples of 7075 aluminum alloy were subjected to cold extrusion, and semi-solid treatment was carried out for 5-30 min at temperatures ranging from 580 to 605℃. A backward-extrusion experiment was conducted to investigate liquid segregation during the thixoforming process. The results revealed that obvious grain coarsening and spheroidization occurred during prolonged isothermal treatments. In addition, higher soaking temperatures promoted the spheroidization and coarsening process because of the increased liquid fraction and the melting of second phases. Segregation of the liquid phase caused by the difference in fluidity between the liquid and the solid phases was observed in different regions of the thixoformed specimens.

关键词： aluminum alloys microstructural evolution thixoforming grain coarsening segregation

Evaluation of five antibiotics on larval gut bacterial diversity of Plutella xylostella （Lepidoptera： Plutellidae）

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Insect Science 2015年第5期22卷 619-628页

作者： xiao-li lin Zhi-wei Kang Qin-Jian Pan Tong-Xian liu State Key Laboratory of Crop Stress Biology in Arid Areas and Key Laboratory of Northwest Loess Plateau Crop Pest Managementof Ministry of Agriculture Northwest A&F University Yangling Shaanxi 712100 China

Larvae of the diamondback moth, Plutella xylostella L. （Lepidoptera： Plutelli- dae）, have rich microbial communities inhabiting the gut, and these bacteria contribute to the fitness of the pest. In this study we evaluated the effects of five antibiotics （rifampicin, ampicillin, tetracycline, streptomycin sulfate and chloramphenicol） on the gut bacterial di- versity ofP xylostella larvae. We screened five different concentrations for each antibiotic in a leaf disc assay, and found that rifampicin and streptomycin sulfate at 3 mg/mL signif- icantly reduced the diversity of the bacterial community, and some bacterial species could be rapidly eliminated. The number of gut bacteria in the rifampicin group and strepto- mycin sulfate group decreased more rapidly than the others. With the increase of antibiotic concentration, the removal efficiency was improved, whereas toxic effects became more apparent. All antibiotics reduced larval growth and development, and eventually caused high mortality, malformation of the prepupae, and hindered pupation and adult emergence. Among the five antibiotics, tetracycline was the most toxic and streptomycin sulfate was a relatively mild one. Some dominant bacteria were not affected by feeding antibiotics alone. Denaturing gradient gel electrophoresis graph showed that the most abundant and diverse bacteria in P xylostella larval gut appeared in the cabbage feeding group, and diet change and antibiotics intake influenced gut flora abundance. Species diversity was significantly reduced in the artificial diet and antibiotics treatment groups. After feeding on the artificial diet with rifampicin, streptomycin sulfate and their mixture for 10 days, larval gut bacteria could not be completely removed as detected with the agarose gel electrophoresis method.

关键词： antibiotics endosymbiont gut bacteria microbes PCR-DGGE

TSV Minimization for Circuit Partitioned 3D SoC Test Wrapper Design

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Journal of Computer Science & Technology 2013年第1期28卷 119-128页

作者： Yuan-Qing Cheng Lei Zhang Yin-He Han xiao-wei li State Key Laboratory of Computer Architecture Institute of Computing Technology Chinese Academy of Sciences Beijing 100190 China Graduate University of Chinese Academy of Sciences Beijing 100049 China

Semiconductor technology continues advancing, while global on-chip interconnects do not scale with the same pace as transistors, which has become the major bottleneck for performance and integration of future giga-scale ICs. Thre dimensional （3D） integration has been proposed to sustain Moore＇s law by incorporating through-silicon vias （TSVs） to integrate different circuit modules in the vertical direction, which is believed to be one of the most promising techniques to tackle the interconnect scaling problem. Due to its unique characteristics, there are many research opportunities, and in this paper we focus on the test wrapper optimization for the individual circuit-partitioned embedded cores within 3D System-on- Chips （SoCs）. Firstly, we use existing 2D SoCs algorithms to minimize test time for individual embedded cores. In addition, vertical interconnects, i.e., TSVs that are used to construct the test wrapper should be taken into consideration as well. This is because TSVs typically employ bonding pads to tackle the misalignment problem, and they will occupy significant planar chip area, which may result in routing congestion. In this paper, we propose a series of heuristic algorithms to reduce the number of TSVs used in test wrapper chain construction without affecting test time negatively. It is composed of two steps, i.e., scan chain allocation and functional input/output insertion, both of which can reduce TSV count significantly. Through extensive experimental evaluations, it is shown that reduce the number of test TSVs dramatically, i.e., as much as 26% in comparison with the intuitive method. the test wrapper chain structure designed by our method can 60.5% reductions in comparison with the random method and

关键词： three-dimensional system-on-chip test wrapper chain through-silicon vias optimization

Synthesis,Biological Evaluation and Molecular Modeling of Cyclic Tetrapeptide Based Inhibitors HDAC

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Chemical Research in Chinese Universities 2012年第6期28卷 1011-1016页

作者： li xiao-hui wei Ying-dong WANG Shi-miao WANG Meng-nan HUANG Da-wei XIU Zhi-long School of life Science and Biotechnology Dalian University of Technology Dalian 116024 P. R. China

Histone deacetylases（HDACs） are considered to be among the most promising targets for the development of anti-cancer drugs,and HDAC inhibitors（HDACIs） have become a promising class of anti-cancer *** explore whether thioacetyl group as the zinc binding group（ZBG） and a slight change in the hydrophobicity of the recognition domain of HDACIs could alter their activities,we synthesized a series of cyclo[-L-Am7（SAc）-Aib-L-Phe（n-Cl）D-Pro-] and evaluated their HDAC-inhibitory and antiproliferative *** results show that these peptides could inhibit HDAC at 10-9 mol/L level,and could selectively inhibit the proliferation of three human cancer cell lines with IC 50 at 10-6 mol/L *** study was conducted to examine the mechanisms by which these peptides interact with *** appeared that a zinc ion in the active site of HDAC was coordinated by the carbonyl oxygen atom of the ZBG in the *** the ZBG domain of all the peptides and the surface recognition domain of cyclo[-L-Am7（SAc）-Aib-L-Phe（o-Cl）-D-Pro-] and that of cyclo[-L-Am7（SAc）-Aib-L-Phe（m-Cl）-D-Pro-] interacted with HDAC2 via hydrogen *** interaction has been considered to provide favorable contributions to stabilizing the complexes,and the introduction of a chlorine atom at the aromatic ring on the L-Phe position of these peptides affected the interaction between each of these inhibitors and the enzyme,resulting in slight change in the structure of the surface recognition domain of the peptides.

关键词： Histone deacetylase(HDAC) Histone deacetylase inhibitor(HDACI) Cyclic tetrapeptide Anti-cancer agent Antiproliferative activity Docking

CRISPR/Cas9-based mutation reveals Argonaute 1 is essential for pigmentation in Ostrinia fumacalis

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Insect Science 2019年第6期26卷 1020-1028页

作者： Lang You Hong-Lun Bi Yao-Hui Wang xiao-wei li Xi-En Chen Zhi-Qian li CAS Key Laboratory of Insect Developmental and Evolutionary Biology CAS Center for Excellence in Molecular Plant Sciences Shanghai Institute of Plant Physiology and Ecology Chinese Academy of Sciences Shanghai China

Ostrinia fumacalis (Lepidoptera: Pyralidae) is one of the most destructive agricultural pests in Asia. Traditional pest-management methods include sex pheromone capture, transgenic crops that produce Bacillus thuringiensis toxin, and pesticides. Although these strategies control pest populations effectively, they also cause negative side effects, including dramatically increased pesticide resistance, severe pollution, and hazards for human health. Recently developed genome editing tools provide new prospects for pest management and have been successfully used in several species. However, few examples have been reported in the agricultural pest O. fumacalis due to a lack in genomic information. In this report, we identified only one transcript of O. fumacalis Argonaute 1 (OfAgo 1) gene from the genome and cloned the open reading frame. OfAgol presented the maximum expression at the embryo stage or in the fat body during the larval stages. To understand its function, an OfAgol mutant was constructed using the Clustered Regularly Interspaced Short Palindromic Repeat/RNA-guided Cas9 nuclease (CRISPR/Cas9). Mutagenesis of OfAgol disrupted cuticle pigmentation by dowregulating micro RNAs and pigmentation-related genes. This is the first report for the cloning and functional analysis of OfAgol, revealing a role of OfAgol in cuticle pigmentation. The current report also established a CRISPR/Cas9 system in O. fumacalisy providing a new insight for pest management.

关键词： Agol CRISPR/Cas9 cuticle pigmentation Ostrinia fumacalis pest management

Evaluation of the treatment effect of rear slope cutting on hydrodynamic pressure landslides:A case study

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Journal of Mountain Science 2023年第7期20卷 1968-1983页

作者： WANG li HUANG Jun-jie CHEN Yong WANG Shi-mei FAN Zhi-hong GUO Fei li xiao-wei Key Laboratory of Geological Hazards on Three Gorges Reservoir Area(China Three Gorges University) Ministry of EducationYichang 443002China College of Civil Engineering&Architecture China Three Gorges UniversityYichang 443002China Badong National Observation and Research Station of Geohazards China University of GeosciencesWuhan 430074China Central-South Institute of Metallurgical Geology Yichang 443002China

After the impoundment of the Three Gorges Reservoir,some huge ancient landslides were reactivated and deformed,showing typical hydrodynamic pressure landslide *** Baishuihe landslide was a typical hydrodynamic pressure *** management department conducted slope cutting treatments from 2018 to *** evaluate the treatment effect of rear slope cutting,this study analyzed the data of the surface deformation survey and field monitoring over the past 20 years and the characteristics of the reservoir water-triggered Baishuihe landslide deformation,and calculated the seepage field,displacement field,and stability coefficient before and after landslide *** results showed that the deformation of the Baishuihe landslide was primarily related to a decrease in the reservoir water *** to the poor permeability of the landslide soil,the decrease in the reservoir water level produced a seepage force pointing to the outside of the landslide body,leading to the step deformation of the landslide *** landslide was treated by rear slope cutting,and the“step”deformation of the landslide disappeared after *** hydrodynamic pressure caused by the change in reservoir water after cutting the slope did not ***,as the slope cutting greatly reduced the overall sliding force of the landslide,its stability was greatly ***,high stability can still be ensured under extreme rainfall after *** cutting is effective for treating hydrodynamic pressure *** study can provide effective technical support for the treatment of reservoir landslides.

关键词： Hydrodynamic pressure landslide Three Gorges Reservoir Slope cutting Load reduction Landslide monitoring Ancient landslides Reservoir water level fluctuation