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Asymptotic Speed of Wave Propagation for A Discrete Reaction-Diffusion Equation

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Acta Mathematicae Applicatae Sinica 2006年第3期22卷 369-386页

作者： Xiu-xiang Liu Pei-xuan Weng School of Mathematics Science South China Normal University Guangzhou 510631 China

We deal with asymptotic speed of wave propagation for a discrete reactlon-diffusion equation. We find the minimal wave speed c★ from the characteristic equation and show that c★ is just the asymptotic speed of wave propagation. The isotropic property and the existence of solution of the initial value problem for the given equation are also discussed.

关键词： Discrete reaction-diffusion equation travelling wave solutions monotone iteration asymptotic speed of wave propagation isotropic property

Zinc lactate alleviates oxidative stress by modulating crosstalk between constitutive androstane receptor signaling pathway and gut microbiota profile in weaned piglets

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Animal Nutrition 2024年第1期16卷 23-33页

作者： Wenjie Tang xuan xiang Houfu Wang Wentao Zhou Liuqin He Yulong Yin Tiejun Li College of Animal Science and Technology Hunan Agricultural UniversityChangsha 410128China Hunan Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process CAS Key Laboratory of Agro-Ecological Processes in Subtropical RegionNational Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry ProductionInstitute of Subtropical AgricultureChinese Academy of SciencesChangsha 410125China Hunan Provincial Key Laboratory of Animal Intestinal Function and Regulation Laboratory of Animal Nutrition and Human HealthCollege of Life SciencesHunan Normal UniversityChangsha 410081China College of Advanced Agricultural Science University of Chinese Academy of SciencesBeijing 100049China Sichuan Academy of Animal Sciences Animal Breeding and Genetics Key Laboratory of Sichuan ProvinceChengdu 610066China Livestock and Poultry Biological Products Key Laboratory of Sichuan Province Sichuan Animtech Feed Co.LtdChengdu 610000China

This study aimed to determine the regulatory mechanism of dietary zinc lactate(ZL)supplementation on intestinal oxidative stress damage in a paraquat(PQ)-induced piglet ***-eight piglets(mean body weight 9.51±0.23 kg)weaned at 28 d of age were randomly divided into control,ZL,PQ,and ZL+PQ groups(n=7 in each group).The ZL-supplemented diet had little effect on growth performance under normal physiological ***,under PQ challenge,ZL supplementation significantly improved average daily gain(P<0.05)and reduced the frequency of *** improved intestinal morphology and ultrastructure by significantly increasing the expression level of the jejunal tight junction protein,zonula occludens-1(ZO-1)(P<0.05),and intestinal zinc transport and absorption in PQ-induced piglets,which reduced intestinal *** supplementation also enhanced the expression of antioxidant and antiinflammatory factor-related genes and decreased inflammatory cytokine expression and secretion in PQinduced ***,ZL treatment significantly inhibited the activation of constitutive androstane receptor(CAR)signaling(P<0.01)in PQ-induced piglets and altered the structure of the gut microbiota,especially by significantly increasing the abundance of beneficial gut microbes,including UCG_002,Ruminococcus,Rikenellaceae_RC9_gut_group,Christensenellaceae_R_7_group,Treponema,unclassified_Christensenellaceae,and unclassified_Erysipelotrichaceae(P<0.05).These data reveal that pre-administration of ZL to piglets can suppress intestinal oxidative stress by improving antioxidant and anti-inflammatory capacity and regulating the crosstalk between CAR signaling and gut microbiota.

关键词： Zinc lactate Intestinal barrier Oxidative stress Inflammation Constitutive androstane receptor Gut microbiota

Can Hybrid Synapse be Formed between Rat Spinal Motor Neurons and Major Pelvic Ganglion Neurons in vitro?

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Wuhan University Journal of Natural Sciences 2021年第6期26卷 521-526页

作者： CHENG Shigang xiang xuan LV Zemin MAO Xiaowen YANG Xinghai Department of Surgery Maternal and Child Health Hospital of Hubei ProvinceTongji Medical College of Huazhong University of Science and TechnologyWuhan 430070HubeiChina

The purpose of this study is to determine whether synapses can be formed between spinal motor neurons(SMNs)and major pelvic ganglion(MPG)neurons of a rat in *** green fluorescent protein(GFP)-labelled MPG cells were cultured together with SMNs in a specific *** synaptic-like contacts established between SMNs and MPG neurons were studied in co-cultures using morphologic and immunocytochemistry ***-contrast observation of co-cultures showed apparent SMNs-MPG neurons contacts as early as three or four days in *** demonstrate some evidence of synaptic contacts between SMNs and MPG neurons in vitro by immunostaining with antibody directed against postsynaptic density protein 95(PSD-95).We describe the development process of a defined SMNs-MPG neurons co-culture *** results suggest that the hybrid synapse formation that may occur between SMNs and MPG neurons in vitro played an essential role in the mechanisms of a regenerated bladder with an artificial somatic-autonomic reflex arc.

关键词： spinal motor neurons major pelvic ganglion co-culture synapse

Plasma exchange in patients with acute and acute-on-chronic liver failure: A systematic review

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World Journal of Gastroenterology 2020年第2期26卷 219-245页

作者： Eunice xiang-xuan Tan Min-Xian Wang Junxiong Pang Guan-Huei Lee National University Health System Singapore 119228Singapore Centre for Infectious Disease Epidemiology and Research Saw Swee Hock School of Public HealthNational University of SingaporeSingapore 119077Singapore National University of Singapore Singapore 119077Singapore

BACKGROUND Acute liver failure(ALF)and acute-on-chronic liver(ACLF)carry high short-term mortality rate,and may result from a wide variety of *** exchange has been shown in a randomized control trial to improve survival in ALF especially in patients who did not receive a liver *** cohort studies demonstrated potential improvement in survival in patients with *** To assess utility of plasma exchange in liver failure and its effect on mortality in patients who do not undergo liver *** Databases MEDLINE via PubMed,and EMBASE were searched and relevant publications up to 30 March,2019 were *** were included if they involved human participants diagnosed with liver failure who underwent plasma exchange,with or without another alternative non-bioartificial liver assist *** Three hundred twenty four records were reviewed,of which 62 studies were found to be *** the 262 records screened,211 studies were ***-one articles were assessed for eligibility,for which 7 were ***-nine studies were included for ALF only,and 9 studies for ACLF *** studies included both ALF and ACLF patients.A total of 44 publications were *** the included publications,2 were randomized controlled trials,14 cohort studies,12 case series,16 case *** of three ALF studies which looked at survival rate or survival days reported improvement in outcome with plasma *** two out of four studies where plasma exchange-based liver support systems were compared to standard medical treatment(SMT)for ACLF,a biochemical improvement was *** in the non-transplanted patients was improved in all four studies in patients with ACLF comparing plasma exchange vs *** the aforementioned studies,plasma exchange based therapy in ACLF compared to SMT improved survival in non-transplanted patients at 30 and 90-d with a pooled OR of 0.60(95%CI 0.46-0.77,P<0.01).CONCLUSION The level of ev

关键词： Acute-on-chronic liver failure Acute liver failure Plasmapheresis Plasma exchange Liver failure

Synthesis and characterization of HPMA copolymer-5-FU conjugates

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Chinese Chemical Letters 2008年第2期19卷 137-140页

作者： Fang Yuan Fu Chen Qing Yu xiang xuan Qin Zhi Rong Zhang Yuan Huang Key Laboratory of Drug Targeting of Ministry of Education West China School of Pharmacy Sichuan University Chengdu 610041 China

N-（2-Hydroxypropyl） methacrylamide copolymer-5-fluorouracil （PHPMA-FU） conjugates were synthesized by a novel and simplified synthetic route, and characterized by UV, FTIR and HPLC analyses. The conjugated content of 5-fluorouracil （5-FU） was 3.41 ± 0.07 wt%. The stabilities of PHPMA-FU conjugates under different conditions were studied. The results showed that HPMA copolymer was a potential carrier for tumor-targeting delivery of 5-FU.

关键词： HPMA copolymer 5-Fluorouracil Conjugates Characterization Stability

Transition-Metal-Free Catalyzed Dehydrative Coupling of Quinoline and Isoquinoline N-Oxides with Propargylic Alcohols

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Chinese Journal of Chemistry 2022年第1期40卷 71-78页

作者： Zhao-Nan Cai xiang-xuan Feng Yuecheng Zhang Cong-Cong Lu Ya-Ping Han Jiquan Zhao School of Chemical Engineering and Technology Hebei University of TechnologyTianjin 300130China

A novel,green,and transition-metal-free protocol for the facile modification of quinoline and isoquinoline derivatives is introduced,starting from readily available and environmentally benign quinoline and isoquinoline N-oxides with propargylic alcohols in the presence of Na_(2)S_(2)O_(8) or K_(2)S_(2)O_(8) at 100℃.The one-pot transformation features the advantages of good functional group compatibility,short reaction time,operational simplicity,and highly efficient reaction *** protocol,which produces water as the only byproduct,provides efficient and atom-economical access to a class of fascinating quinoline and isoquinoline products in satisfactory *** method is effective on the gram scale,thus highlighting the inherent practicality of this methodology.

关键词： Synthetic methods Alcohols Nitrogen heterocycles Transition-metal-free Solvent-free

Changing to Poly（rod-coil） Polymers： A Promising Way for an Optoelectronic Compound to Improve Its Film Formation

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Chinese Journal of Chemistry 2015年第8期33卷 847-851页

作者： Wei Shao Long Liang xuan xiang Hong-Jiao Li Fu-Gang Zhao Wei-Shi Li Department of Chemistry Key Laboratory of Advanced Textile Materials and Manufacturing Technology of Education Ministry Zhejiang Sci- Tech University Hangzhou Zhejiang 310018 China Key Laboratory of Synthetic and Self-assembly Chemistry for Organic Functional Molecules Shanghai Institute of Organic Chemistry Chinese Academy of Sciences Shanghai 200032 China

Good film formation is one of basic requirements for organic optoelectronic materials to achieve the capability for fabrication of large area devices. Small molecular optoelectronic compounds have a definite chemical structure and clear device performance, and thus are welcomed in the field. However, they are generally suffering from poor film formation, especially in a large area. For addressing it, this contribution proposes and demonstrates a strategy, that is, changing them into poly（rod-coil） polymers. With one optoelectronic compound [BDT（DTBT）2] and three poly（rod-coil） polymers （P1, P2, and P3） having different non-conjugated coil segments as examples, the work clearly shows that the change to poly（rod-coil） polymers keeps many basic optoelectronic properties of the refer- ence compound, including light absorption in solution, bandgap and frontier orbital energy levels, but suppresses strong intermolecular interactions and crystalline structure in film state. Further comparisons on film formation quality on glass and ITO glass illustrate that all the three polymers have a better film formation property than the reference compound.

关键词： organic optoelectronic materials poly(rod-coil) polymers film formation

Metrology and Energy Conservation

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China Standardization 2006年第4期51卷 4-8页

作者： xuan xiang Department of Metrology of General Administration of Quality Supervision Inspection and Quarantine of the People''s Republic of China (AQSIQ)

May 20 is World Metrology Day and the theme of this year is ''Metrology andEnergy Conservation.'' Energy is not only a vital issue for China, but also for the world. In orderto implement Proposal of the CPC Central Committee on the 11 th Five-Year Program for NationalEconomic and Social Development, the government bulletin of 5th Plenary Session of the 16th CPCCentral Committee announced that ''there shall be marked improvement on resource utilization; theenergy consumption for unit GDP shall cut 20%, water consumption of unit industrial added value drop30%... and the recycle ratio of industrial solid wastes shall raise by 60%.'' These are key targetsof economic development during the 11th five-year program. To make full use of metrology for energyconservation and energy utilization, the competent metrology department of Chinese Governmentadvanced metrology program in light of China''s energy status.

关键词： Metrology and Energy Conservation OIML over

Talking about Metrology and Energy On World Metrology Day

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China Standardization 2005年第4期50卷 14-17页

作者： xuan xiang Department of Metrology of General Administration of Quality Supervision

The theme of this year' s World Metrology Day is 'Metrology and Energy'. Theenergy problem is an important issue for the whole world and has received great attention in Chinasince China is both a big energy-consuming country and a country severely short of energy. Under theenergy and environmental pressure, China will take measures in the following four respects in orderto solve the problem of energy shortage: China will stick to the self-reliance principle for energysupply, since China has abundant coal resources, which have formed the mainstream of its energysupply. The coal resources account for 67 percent of energy supply and the self-reliant supply rateof coal has reached as high as 94 percent. China will take action to tap more resources and saveenergy consumption. China will attach greater importance to the development and exploitation ofrenewable energy resources. China will conduct international cooperation at an appropriate level.

关键词： Talking about Metrology and Energy On World Metrology Day World