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Real-time Quantitative RT-PCR for CT9 Level in Human Cancer

Chemical Research in Chinese Universities 2006年第2期22卷 185-188页

作者： JIN xiang-qun ZHANG Jing-min XU Hui ZHOU Yan WANG guang-shu ZHAO Yan-qiu ZHANG Han-qi College of Chemistry Jilin University Changchun 130012 P. R. China College of Phamercy Jilin University Changchun 130021 P. R. China College of Nurse Jilin University Changchun 130021 P. R. China No. 2 Affiliated Hospital Jilin University Changchun 130021 P. R. China

CT9 is a recently cloned cancer-testis antigen, which is a member of the bromodomain and extraterminal family. Each member of this protein family contains two N-terminal bromodomain motifs. We investigated the distribution of CT9 in different tissues and the possibility for it to be used as a potential therapeutic target in cancer treament. By using the real-time RT-PCR method and 18SrRNA as an internal standard, we analyzed the CT9 expression in several normal human tissues and in the tissues of patients suffering from cancer. The result of this study shows that the highest level of mRNA is only present in testis tissue because the CT9 expression has not been detected in other normal tissues. In 6 of 10 cases of gastric adenocarcinoma, in 3 of 10 cases of esophageal squamous cell carcinoma, in 2 of 9 cases of endometrial carcinoma and only in 1 of 12 cases of brain cancer, the low level expression of CT9 was detected. In none of the 12 cases of cervical squamous cell carcinoma, the expression of CT9 was detected. Since the high level expression of CT9 is only found in the normal testis tissue, but the low expression in cancer tissues, for example tissues of cervical squamous cell carcinoma, brain cancer, endometfial adenocarcinoma, esophageal squamous cell carcinoma, we conclude that CT9 cannot be used as a cancer therapeutic target molecule for cervical squamous cell carcinoma, brain cancer, endometrial adenocarcinoma, esophageal squamous cell carcinoma.

关键词： CT9 Cancer-testis antigen Real-time RT-PCR

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New matrix of MALDI-TOF MS for analysis of small molecules

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Chinese Chemical Letters 2009年第12期20卷 1495-1497页

作者： shu Zhang Yi Chen Jian An Liu Shao xiang Xiong guang Hui Wangx Jun Chen Guo Qiang Yang Institute of Chemistry Chinese Academy of Sciences Beijing 100190 China Graduate University of Chinese Academy of Sciences Beijing 100049 China

New matrix, metal-phthalocyanine （MPc）, of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry （MALDI-TOF MS） was used for analysis of small molecules （usually 〈500 Da）. By using MPcs as matrices, small molecular samples were moved to high mass-to-charge region where there was no interference caused by the traditional matrices. The mass of the target analvte was obtained by simple calculation.

关键词： MALDI-TOF MS Small molecules Metal-phthalocyanines New matrix

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Thermal conductivity of cast iron-A review

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China Foundry 2020年第2期17卷 85-95页

作者： guang-hua Wang Yan-xiang Li School of Materials Science and Engineering Tsinghua UniversityBeijing 100084China Key Laboratory for Advanced Materials Processing Technology Ministry of EducationBeijing 100084China

This paper gives a brief introduction to the four research methods for the study on thermal conductivity of cast irons,including experimental measurement,statistical analysis,effective medium theory and numerical *** studies on the thermal conductivity of various cast irons are reviewed through the influence of alloying elements,structural constituents,and *** addition of alloying elements is the main reason that restricts the thermal conductivity of cast irons,especially spheroidal graphite cast *** connectivity of graphite has a significant effect on the thermal conductivity of flake and compacted graphite cast irons,semiquantitative and quantitative analysis of this factor is a key and difficult point in the study of thermal conductivity of cast *** thermal conductivities of different types of cast irons show varying degrees of dependence on *** phenomenon is the combination of graphite and matrix,rather than just depending on graphite *** study of the relationship between individual phase and temperature is the focus of future *** summaries and discussions may provide reference and guidance for the future research and development of high thermal conductivity cast irons.

关键词： cast iron thermal conductivity gray cast iron nodular castiron compacted graphite cast iron

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Is traumatic meniscal lesion associated with acute fracture morphology changes of tibia plateau? A series of arthroscopic analysis of 67 patients

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World Journal of Clinical Cases 2021年第1期9卷 81-90页

作者： Yan-Dong Chen shu-xiang Chen Hong-guang Liu xiang-Sheng Zhao Wen-Huan Ou Huan-Xi Li Hong-Xing Huang 3^rd Institute of Clinical Medicine Guangzhou University of Chinese MedicineGuangzhou 510000Guangdong ProvinceChina Department of Joint Trauma Jiangmen Wuyi Hospital of Traditional Chinese MedicineAffiliated Jiangmen Traditional Chinese Medicine Hospital of Jinan UniversityJiangmen 529031Guangdong ProvinceChina Department of Radiology Jiangmen Wuyi Hospital of Traditional Chinese MedicineJiangmen 529031Guangdong ProvinceChina Science and Education Section The Third Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhou 510378Guangdong ProvinceChina

BACKGROUND Computed tomography(CT)has become a routine preoperative examination for tibial plateau fractures(TPFs).Assessing the location of the fragment and intercondylar eminence fracture can provide clinicians with valuable information;however,the evaluation of traumatic meniscal lesion(TML)and arthroscopic management are *** To predict TML by three-dimensional skeletal anatomy changes in unilateral TPF and bilateral TPF on preoperative thin layer *** Acute fracture of tibial plateau patients undergoing arthroscopic surgery between December 2017 and December 2019 were included in this retrospective *** type,zone,and location of TMLs were diagnosed based on the operation records and/or arthroscopic *** of three-dimensional fracture morphology included the following:Frontal fragment width of plateau,sagittal fragment subsiding distance(FSD),sagittal fracture line distance,sagittal posterior tibial slope,and transversal area ratio of fragment area)on preoperative CT three-dimensional *** correlation of TML with skeletal values was calculated according to unicondylar TPFs and bicondylar *** A total of 67 patients were enrolled in this study,among which 30 patients had TMLs,lateral/medial(23/7).FSD was a particularly positive factor to predict TML,with odds ratio of 2.31(1.26-5.63).On sagittal view of CT,FSD degree of 8 mm and posterior tibial slope exceeding 11.74°implied enhanced risk of TML in bicondylar *** coronal view,once fragment width of plateau surpassed 3 cm,incidence of TML reached 100%.On transverse view,area ratio of fragment as enhanced risk of 5.5%and FSD>4.3 mm for predicting TML were observed in unicondylar *** TML can be predicted by different parameters on preoperative CT views according to unicondylar fractures and bicondylar TPFs.

关键词： Traumatic meniscal lesion Knee Three-dimensional computerized tomography Posterior tibial slope Unicondylar fracture Bicondylar fracture

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Calculating the effective thermal conductivity of gray cast iron by using an interconnected graphite model

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China Foundry 2020年第3期17卷 183-189页

A new theoretical model of gray cast iron taking into account a locally interconnected structure of flake graphite was designed,and the corresponding effective thermal conductivity was calculated using the thermal resistance network *** calculated results are obviously higher than that of the effective medium approximation assuming that graphite is distributed in *** is suggested that the interconnected structure significantly enhances the overall thermal ***,it is shown that high anisotropy of graphite thermal conductivity,high volume fraction of graphite,and small aspect ratio of flake graphite will cause the connectivity effects of graphite to more obviously improve the overall thermal *** graphite volume fraction,lower aspect ratio and higher matrix thermal conductivity are beneficial to obtain a high thermal conductivity gray cast *** work can provide guidance and reference for the development of high thermal conductivity gray cast iron and the design of high thermal conductivity composites with similar locally interconnected structures.

关键词： gray cast iron effective thermal conductivity flake graphite interconnected graphite structure

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我国钛白粉行业现状及钛石膏处置利用政策建议

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现代化工 2025年第1期45卷 7-12页

作者：郭卫广罗大鹏向璟荣佟洪金雍毅四川省生态环境科学研究院四川成都610041 四川省环境保护固体废物处理处置工程技术中心四川成都610041

为提高钛石膏处置利用水平,推进我国“无废城市”工作,在全国范围内调研了钛白粉行业技术发展现状,全生命周期分析了钛石膏产生、处置和利用技术应用现状。采集了全国30个钛石膏样品并进行成分分析,总结了钛石膏产、排和处置利用面临的... 详细信息

为提高钛石膏处置利用水平,推进我国“无废城市”工作,在全国范围内调研了钛白粉行业技术发展现状,全生命周期分析了钛石膏产生、处置和利用技术应用现状。采集了全国30个钛石膏样品并进行成分分析,总结了钛石膏产、排和处置利用面临的问题并提出以下政策建议:引导产业结构调整,源头上实现“无废”,加大废酸回收利用量,过程上尽量“减废”,提升废水清洁化生产水平,以资源回收替代末端治理,探寻钛石膏高质量规模化利用途径,以增效赋值替代传统堆存等。

关键词：钛白粉钛石膏处置利用政策建议

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Inter-valley spiral order in the Mott insulating state of a heterostructure of trilayer graphene-boron nitride

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Science Bulletin 2018年第17期63卷 1087-1091页

作者： Guo-Yi Zhu Tao xiang guang-Ming Zhang State Key Laboratory of Low-Dimensional Quantum Physics and Department of Physics. Tsinghua University Beijing 100084 China Institute of Physics. Chinese Academy of Sciences Beijing 100190 China Collaborative Innovation Center of Quantum Matter Beijing 100084 China

Recent experiment has shown that the ABC-stacked trilayer graphene-boron nitride Moire super-lattice at half-filling is a Mort insulator. Based on symmetry analysis and effective band structure calculation, we propose a valley-contrasting chiral tight-binding model with local Coulomb interaction to describe this Moire super-lattice system. By matching the positions of van Hove points in the low-energy effective bands, the valley-contrasting staggered flux per triangle is determined around π/2. When the valence band is half-filled, the Fermi surfaces are found to be perfectly nested between the two valleys. Such an effect can induce an inter-valley spiral order with a gap in the charge excitations, indicating that the Mott insulating behavior observed in the trilayer graphene-boron nitride Moire super-lattice results predominantly from the inter-valley scattering,

关键词： Moire superlattice Mott phase Valley Fermi surface nesting Multilayer graphene

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Control of diesel soot and NOx emissions with a particulate trap and EGR

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Journal of Environmental Sciences 2005年第2期17卷 245-248页

作者： LIURui-xiang GAOXi-yan YANGDe-sheng XUXiao-guang InstituteofInternalComustionEngine DalianUniversityofTechnologyDalian116024China

The exhaust gas recirculation(EGR), coupled with a high-collection efficiency particulate trap to simultaneously control smoke and NOx emissions from diesel engines were studied. This ceramic trap developed previously provided the soot cleaning efficiency of 99%, the regeneration efficiency reaches 80% and the ratio of success reaches 97%, which make EGR used in diesel possible. At the presence of EGR, opening of the regeneration control valve of the trap was over again optimized to compensate for the decrease of the oxygen concentration in the exhaust gas resulted from EGR. The results indicated the cleaning efficiency and regeneration performance of the trap were maintained at the same level except that the back pressure increased faster. A new EGR system was developed, which is based on a wide range oxygen(UEGO) sensor. Experiments were carried out under steady state conditions while maintaining the engine speed at 1600 r/min, setting the engine loads at 0%, 25%, 50%, 75% and 100% respectively. Throughout each test the EGR rate was kept at nine different settings and data were taken with the gas analyzer and UEGO sensor. Then, the EGR rate and engine load maps, which showed the tendencies of NOx, CO and HC emissions from diesel engine, were made using the measured data. Using the maps, the author set up the EGR regulation, the relationship between the optimal amounts of EGR flow and the equivalence ratio,σ, where σ=14.5/AFR.

关键词： particulate trap EGR NOx soot UEGO

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Red Light—Emitting—Diode Based on an Organic Salt

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Chinese Physics Letters 2003年第6期20卷 935-937页

作者： MENGRui-Ping XUHong-guang XUChun-xiang ZHANGJun-xiang HEGuo-Hua CUIYi-Ping DepartmentofElectronicEngineering SoutheastUniversityNanjing210096

A novel organic salt trans-4-[P-(N-ethyl-N-(hydroxylethyl)-amino) styryl]-N-methylpyridinium tetraphenylborate (abbreviated as ASPT) has been employed as an active layer in an organic electroluminescent device. Bright red emission with high quantum efficiency has been obtained. The brightness of the ASPT device is one order magnitude higher than that of Alq3 devices at about 12V. The device shows high thermal stability because of the ionic interaction within the organic salt molecules. It is assumed that the high performance of such a device is related to the formation of dipole moments in the ASPT layer.

关键词： Electroluminescence

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The Realization of Terahertz Image Reconstruction with High Resolution Based on the Amplitude of the Echoed Wave by using the Phase Retrieval Algorithm

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Chinese Physics Letters 2013年第6期30卷 212-215页

作者： GAO xiang LI Chao FANG guang-You Institute of Electronics Chinese Academy of SciencesBeijing 100190 Key Laboratory of Electromagnetic Radiation and Sensing Technology Chinese Academy of SciencesBeijing 100190

An indirect imager working at terahertz band is presented and implemented,which is suitable for high-resolution planar object *** proposed imager employs a simple quasi-optics design to transmit and to receive terahertz waves,and adopts incoherent detection technology to extract the intensity of echoed signal,which results in a relatively low complexity and ***,the Fienup Fourier phase-retrieval algorithm is successfully modified and is applied to retrieve the phase of the echoed signal and reconstruct the target *** experiments on typical planar objects are performed with the imager working at 0.2 THz,and the experimental results demonstrate the good performance of the proposed imager and validate the effectiveness of the reconstruction algorithm.

关键词： image planar optics

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