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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2010年第10期11卷 754-761页

作者： Xiao-hong PAN Ying-xue CHEN Mei-xiang xiang geng XU Jian-an WANG Department of Cardiology the Seeond Affiliated Hospital School of Medicine Zhejiang University Hangzhou 310009 China

A meta-analysis was performed to address the efficacy and safety of paclitaxel-eluting stent(PES) in ST-segment elevation myocardial infarction(STEMI) patients.A systematic literature search was conducted to identify all randomized clinical trials in mortality,recurrent myocardial infarction(rMI),repeat revascularization(RR),and stent thrombosis(ST).A total of 4190 STEMI patients were enrolled in six randomized trials comparing PES with bare-metal stent(BMS).The pooled repeat revascularization rate was 5.7% in PES group,significantly lower than 10.0% in BMS group with an odds ratio(OR) of 0.56,95% confidence interval(CI) [0.44,0.72](P<0.00001).No significant difference was found between PES and BMS groups in mortality at one year after the indexing procedure(3.9% vs.5.1%,OR 0.88,95% CI [0.63,1.21],P=0.42).Similarly,rMI rate did not differ significantly between the two groups(3.4% vs.4.1%,OR 0.80,95% CI [0.56,1.13],P=0.21).PES was also associated with the comparable pooled rate of definite stent thrombosis with BMS(2.3% vs.2.4%,OR 0.81,95% CI [0.52,1.26],P=0.35).The results show that PES improved clinical outcomes in STEMI patients with a decreased need for repeat revascularization and no concerns for safety.

关键词： Myocardial infarction Paclitaxel-eluting stent Bare-metal stent Meta-analysis

Synthesis and Characterization of DOPO-g-CNSL and Its Effect on the Properties of Phenolic Foams

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Journal of Renewable Materials 2019年第10期7卷 1037-1046页

作者： Yufeng Ma Xuanang Gong Bing Xie xiang geng Puyou Jia Nanjing Forestry University College of Materials Science and EngineeringNanjing210037China Institute of Chemical Industry of Forest Products Chinese Academy of Forestry(CAF)Nanjing210042China

In order to improve the mechanical properties without reducing its flame retardancy of phenolic foams(PFs),9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide(DOPO)was introduced in the structure of cashew nut shell liquid(CNSL)to improve its flame retardant,and the product of DOPO grafting CNSL(DOPO-g-CNSL)was obtained to modify phenolic resin,and to prepare DOPO-g-CNSL modified PFs(DCMPFs).The structures of DOPO-g-CNSL were verified by Fourier transform infrared spectroscopy(FT-IR)and nuclear magnetic resonance(1H-NMR).Compared with CNSL,thermal stability of DOPO-g-CNSL was decreased and Ti decreased by 3.53%,but the residual carbon(800°C)was increased by 35.05%.Compared with pure PF,the mechanical properties,toughness and flame retardancy of DCMPFs were increased when the ratio of DOPO-g-CNSL to phenol(DOPO-g-CNSL/P)was no more than 10%.With the dosage of DOPO-g-CNSL/P increased,Ti of DCMPFs was slightly increased,but the carbon residues(800°C)were almost *** the cell sizes of DCMPFs were basically the same as the pure *** comprehensive analysis,the suitable dosage of DOPO-g-CNSL/P was no more than 10%.

关键词： DOPO CNSL modification phenolic foams characterization

Humidity Sensing Properties of Pre-irradiation Grafted HDPE Membranes

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稀有金属材料与工程 2006年第A3期35卷 357-360页

作者： Zheng Jiao Qun Fu xiang geng Zhen Li Haijian Zhong Shanghai Applied Radiation Institute Shanghai University Shanghai 201800 China

Grafted high density polyethylene (HDPE) films have been prepared by grafting sodium styrene sulfonate (SSS) and acrylic acid (AA) onto HDPE using preirradiation *** structure and surface morphology of both grafted and ungrafted HDPE films were observed by FTIR spectroscopy and scanning electron microscope (SEM),*** humidity sensing properties of grafted HDPE films were *** results show that the impedance of the film decreases with increasing of relative humidity (RH).The films display high sensitivity with nearly three orders of magnitude change in the resistance during the relative humidity variation from 5% to 98%.Grafted HDPE films exhibit excellent properties as humidity sensors.

关键词： humidity sensors grafted HDPE films pre-irrsdistion

Mechanical and Magnetic Properties of New(Fe,Co,Ni)–B–Si–Ta Bulk Glassy Alloys

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Acta Metallurgica Sinica(English Letters) 2017年第7期30卷 659-664页

作者： Yao-xiang geng Xin Lin Yu-Xin Wang Jian-Bing Qiang Ying-Min Wang Chuang Dong School of Materials Science and Engineering Jiangsu University of Science and Technology State Key Laboratory of Solidification Processing Northwestern Polytechnical University Key Laboratory of Materials Modification (Ministry of Education) Dalian University of Technology

The alloying effects of the like-atom substitution of Ni and Co for Fe on the various properties of Fe_（70）B_（16.7）Si_（8.3）Ta_5 metallic glass are investigated in this present work. New Fe-based bulk glassy alloys, namely Fe_（60–x）Co_xNi_（10）B_（16.7）Si_（8.3）Ta_5（at.%;x = 10, 20 and 30） with critical diameters up to 1.5 mm, were made by means of copper mold casting.A new glass-forming ability indicator, viz., the enthalpy of supercooled liquid, has been introduced for assessment of the glass-forming abilities（GFAs） of these Fe-based multi-component alloys. Nano-indentation results indicate that the calculated elastic modulus and hardness of the bulk glassy alloys are lower than those of the Fe_（70）B_（16.7）Si_（8.3）Ta_5 *** these bulk glassy alloys, Fe_（70）B_（16.7）Si_（8.3）Ta_5 exhibits the large elastic modulus and hardness with values of 178 ± 1GPa and 12.9 ± 0.1 GPa, respectively. All the bulk glassy alloys exhibit good soft magnetic properties with high saturation magnetization Bs^0.75–1.04 T but low coercive force Hc^0.2–5.2 A/m.

关键词： (Fe Co Ni)–B–Si–Ta bulk glass alloys Glass-forming ability Mechanical property Magnetic property

Impact of probiotics supplement on the gut microbiota in neonates with antibiotic exposure: an open-label single-center randomized parallel controlled study

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World Journal of Pediatrics 2021年第4期17卷 385-393页

作者： Hui Zhong xiang-geng Wang Jing Wang Yan-Jie Chen Huan-Long Qin Rong Yang Department of Pediatrics Shanghai Tenth People’s HospitalTongji University School of MedicineNo.301 Middle Yanchang RoadShanghaiChina Institute for Intestinal Diseases Tongji University School of MedicineNo.301 Middle Yanchang RoadShanghaiChina

Background Antibiotics,a common strategy used for neonatal infection,show consistent effect on the gut microbiota of *** with probiotics has become increasingly popular in mitigating the loss of the gut ***,no clear consensus recommending the use of probiotics in the infection of neonates currently *** study examined the effects of probiotics on the gut microbiota of infectious neonates when used concurrently with or during the recovery period following antibiotic *** Fifty-five full-term neonates diagnosed with neonatal infections were divided into the following groups:NI(no intervention,antibiotic therapy only),PCA(probiotics used concurrently with antibiotics),and PAA(probiotics used after antibiotics).The NI group received antibiotic treatment(piperacillin–tazobactam)for 1 week and the PCA group received antibiotic treatment together with probiotics(Bifidobacterium longum,Lactobacillus acidophilus,and Enterococcus faecalis)for 1 *** PAA group received antibiotic treatment for 1 week followed by probiotics for 1 *** samples were collected at four time nodes:newborn,1 week,2 weeks,and 42 days after *** composition of the gut microbiota was determined by the high-throughput sequencing of 16S rRNA *** Antibiotic exposure was found to dramatically alter gut microbiota,with a significant decrease of Bifidobacterium and *** use of probiotics did not restore the overall diversity of the gut ***,using probiotics simultaneously with the antibiotics was found to be beneficial for the gut microbiota as compared to delaying the use of probiotics to follow treatment with antibiotics,particularly in promoting the abundance of *** These results suggest that the early use of probiotics may have a potential ability to remodel the gut microbiota during recovery from antibiotic ***,further study is required to fully understand th

关键词： Antibiotics Gut microbiota Neonatal infection Probiotics

Crystal Structure of Sar1[H79G]-GDP Which Provides Insight into the Coat-controlled GTP Hydrolysis in the Disassembly of COP Ⅱ

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Chinese Journal of Structural Chemistry 2006年第7期25卷 854-860页

作者： RAO Yi-Jian YUAN Cai BIAN Chuan-Bing HOU Xiao-Min LI Yong-Dong ZHAO geng-xiang YE Xiao-Ming HUANG Zi-xiang HUANG Ming-Dong State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of Matter The Chinese Academy of Sciences Fuzhou Fujian 350002 China

Sarl is a small GTPase involved in COPⅡ vesicle transport. Previous studies showed that H79G mutation of Sarl can lock Sarl in its GTP-bound active conformation, stabilize coat assembly, and prevent the disassembly of COP Ⅱ vesicle coats by reducing Sec23/24 GAP- stimulated hydrolysis. We show here that the replacement of His79 by glycine induces a large conformation change in switch Ⅱ and results in the lost of hydrogen bond between His79 and its associated nucleophilic water molecule that was hypothesized to reduce the GAP-stimulated hydrolysis during the COP Ⅱ assembly and disassembly. These results confirm that the switch Ⅱ conformation is important for COP Ⅱ disassembly through coat-controlled GTP hydrolysis.

关键词： Sarl switch Ⅱ COP Ⅱ disassembly crystal structure

Formation and Structural Evolution of Fe72.5B15.6Si7.8Nb1.7Zr1.7Cu0.7 Nanocrystalline Alloy

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Acta Metallurgica Sinica(English Letters) 2020年第2期33卷 313-318页

作者： Yao-xiang geng Hong-Yu Ding Dong-Peng Wang Zhi-Jie Zhang Hong-Bo Ju Li-Hua Yu Jun-Hua Xu School of Materials Science and Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China Marine Equipment and Technology Institute Jiangsu University of Science and TechnologyZhenjiang 212003China

A 2.5-mm Fe72.5B15.6Si7.8Nb1.7Zr1.7Cu0.7 glassy rod was successfully fabricated using copper mold *** introduction of Cu resulted in the formation of large quantities of a-Fe nanoparticles embedded in the glassy matrix after isothermal *** Fe72.5B15.6Si7.8Nb1.7Zr1.7Cu0.7 nanocrystalline alloy exhibited high saturation magnetization(~1.26 T) and a low coercive force(~0.8 A/m) after annealing at 833 K for 15 min due to the precipitation of ~15-nm-sized a-Fe nanoparticles in the glassy *** structural evolution of the FeBSiNbZrCu amorphous alloy during the annealing process was discussed using a dual-cluster model.

关键词： Nanocrystalline alloy Magnetic property Dual-cluster model Structural evolution

Formation and properties of high Fe-content Fe-(B-Si)-Zr bulk amorphous alloys

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International Journal of Minerals,Metallurgy and Materials 2013年第4期20卷 371-374页

作者： Yao-xiang geng Ying-min Wang Jian-bing Qiang Qing Wang Fan-yang Kong Gui-feng Zhang Chuang Dong Key Laboratory of Materials Modification (Ministry of Education) Dalian University of Technology

The present work is devoted to the development of Fe-（B-Si）-Zr amorphous alloys with high glass-forming ability and good magnetic properties. Using the cluster-plus-glue-atom model proposed for ideal amorphous structures, [FeFe11B3Si]（Fe1-xZrx） was determined as the cluster formula of Fe-（B-Si）-Zr alloys. The glass formation and thermal stability of the serial alloys, namely, [FeFel^B3Si]（Fel_xZrx）（x = 0, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.75, and 1.0）, were studied by the combination of copper mold casting, X-ray diffraction, and differential thermal analysis techniques. The maxima of glass-forming ability and thermal stability were found to occur at the compositions of [FeFe11B3Si] （Fe0.6Zr0.4） and [FeFe11B3Si]（Fe0.5Zr0.5）. The alloys can be cast into amorphous rods with 1.5 ram diameter, and upon reheating, the amorphous alloys exhibit a large undercooled liquid span of 37 K. The saturation magnetization of the [FeFe11B3Si]（Fe0.5Zr0.5） amorphous alloy was measured to be 1.4 T.

关键词： amorphous alloys iron zirconium alloys melt spinning glass-forming ability magnetic properties thermal stability

Tire pyrolysis wastewater treatment by a combined process of coagulation detoxification and biodegradation

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Environmental Science and Ecotechnology 2021年第4期8卷 94-101页

作者： Xiao-ran Shen Chun-xiang geng Bing-Qian Lv Wei Xu Yi Xu Hua-Zhang Zhao Key Laboratory of Water and Sediment Sciences(Ministry of Education) College of Environmental Sciences and EngineeringPeking UniversityBeijing100871People's Republic of China College of Chemistry and Chemical Engineering China University of PetroleumQingdao266555People's Republic of China

Recycling waste tires through pyrolysis technology generates refractory wastewater,which is harmful to the environment if not disposed *** this study,a combined process of coagulation detoxification and biodegradation was used to treat tire pyrolysis *** removal characteristics at the molecular level were investigated using electrospray ionization(ESI)coupled with Fourier transform ion cyclotron resonance mass spectrometry(FT-ICR MS).The results showed that nearly 90%of the organic matter from the wastewater was removed through the *** of the two coagulants for different classes of organics in tire pyrolysis wastewater was *** covalently bound inorganicorganic hybrid coagulant(CBHyC)used in this work had a complementary relationship with biodegradation for the organics removal:this coagulant reduced toxicity and enhanced the biodegradation by preferentially removing refractory substances such as lignin with a high degree of oxidation(O/C>0.3).This study provides molecular insight into the organics of tire pyrolysis wastewater removed by a combined treatment process,supporting the advancement and application of waste rubber recycling *** also contributes to the possible development of an effective treatment process for refractory wastewater.

关键词： Refractory wastewater Molecular composition Recalcitrant substances Biodegradability ESI FT-ICR MS

Fast tool to evaluate 3D movements of the foot-ankle complex using multi-view depth sensors

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Medicine in Novel Technology and Devices 2023年第1期17卷 107-115页

作者： Donggang Jiang Jie-Wen Li xiang geng Xin Ma Wen-Ming Chen Academy for Engineering and Technology Fudan UniversityShanghai200433China Department of Orthopaedics Huashan Hospital Affiliated to Fudan UniversityShanghai200040China

Movement disorders of the human foot-ankle complex are a common occurrence,owing to the altered joint mechanics during foot-ground *** of such movement disorders will require quantitative tools to evaluate in-vivo foot motions,in particular to the multi-segment/joint foot kinematics(MSFK),during ***,current MSFK analysis largely rely on conventional technologies,such as skin-marker based motion capturing,video fluoroscopy and dynamic 3D scanning,being extremely time-consuming and *** this work,a novel movement tracking method,named the point-cloud foot analysis(PFA),was implemented with multi-view depth sensors,to allow fast evaluations of 3D motions of the foot-ankle complex during *** analysis obtained by the PFA methods and their accuracy relative to the conventional MSFK analysis methods were *** 3D surface reconstructions of the foot-ankle complex were achieved with a RMSE less than 2 *** was proven to be feasible to track multi-segment foot motions in both healthy and diseased subjects during walking conditions,with the processing time decreased from more than 4-6 h to less than 6 min for the entire flow of the contact phase *** PFA method can be useful for fast evaluations of the movement disorders of the foot-ankle complex in diagnostics and design of therapeutic interventions and rehabilitation programs for clinical applications.

关键词： Biomechanics Foot model Joint mechanics Movement disorders Depth sensor