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运动转诊服务纳入医疗卫生优先事项的卫生经济学分析

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成都体育学院学报 2024年第1期50卷 112-121页

作者：刘国纯曹春梅马新东张献博王正珍重庆医科大学体育医学学院重庆400331 清华大学体育部北京100084 北京医院内分泌科国家老年医学中心中国医学科学院老年医学研究院北京100730 北京体育大学北京100084

当前,运动转诊服务获得了世界卫生组织推荐,正成为全球公共卫生优先事项。中国体医融合服务尚未获得政策优先级,可能受制于卫生经济学证据不足。文章系统梳理了身体活动不足的全球疾病负担研究,得知:(1)患病率。2010—2018年中国身体活... 详细信息

当前,运动转诊服务获得了世界卫生组织推荐,正成为全球公共卫生优先事项。中国体医融合服务尚未获得政策优先级,可能受制于卫生经济学证据不足。文章系统梳理了身体活动不足的全球疾病负担研究,得知:(1)患病率。2010—2018年中国身体活动不足患病率上升7.93%;(2)健康负担。1990—2019年中国可归因于身体活动不足的死亡人数增长3.24倍、残疾调整寿命年增长2.64倍、健康寿命损失年增长2.89倍、寿命损失年增长2.58倍,过去近30年健康负担持续增长;(3)经济负担。2020—2030年,身体活动不足将引起4 517.01万例12种常见非传染性疾病,导致医疗卫生和医疗保健总成本达到36 694.53亿元;(4)宏观经济收益。2020—2050年解决身体活动不足将为中国带来的累积经济收益41 473.48~150 124.07亿元。这些数据为中国运动转诊服务纳入医疗卫生优先事项提供卫生经济学证据,但提升政策优先级还需:(1)进行独立的中国身体活动不足的疾病负担测算,为医疗卫生政策提供可靠证据;(2)将运动转诊作为中国非传染性疾病治理的优先政策;(3)建立运动转诊机制,并将运动转诊服务纳入医疗卫生服务目录。

关键词：运动转诊身体活动不足非传染性疾病负担医疗卫生服务优先事项全民健身

Exogenous melatonin alleviated growth inhibition and oxidative stress induced by drought stress in apple rootstock

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BIOCELL 2022年第7期46卷 1763-1770页

作者： MEIGE WANG JUAN GONG CHUNHUI SONG ZHENGYANG WANG SHANGWEI SONG JIAN JIAO MIAOMIAO WANG xianbo zhang TUANHUI BAI College of Horticulture Henan Agricultural UniversityZhengzhou450002China

Drought stress is one of the major environmental obstacles that limit the production and development of apples(Malus domestica Borkh.).The role of melatonin is well known in the protection of plants under environmental *** this study,we investigated the effect of melatonin on apple rootstock *** Rehd under drought *** results showed that drought inhibited the growth of *** and dramatically reduced root surface area,root volume,the number of tips and forks,and root ***-induced growth inhibition was significantly decreased by adding *** photosynthetic rate(Pn),intercellular CO_(2)concentration(Ci),stomatal conductance(Gs),transpiration rate(Tr),were markedly reduced under drought ***,the application of melatonin could mitigate the damage to the photosynthetic apparatus and increase the quantum yield of PSII ***,generation of hydrogen peroxide(H_(2)O_(2))and superoxide radicals(O_(2)^(•–))sharply increased in apple leaves after 4 days under drought stress,and the accumulation of electrolyte leakage(EL)represented oxidative stress,while by applying melatonin under drought stress,the generation of O_(2)^(•–)and H_(2)O_(2)were significantly reduced and protected the membrane from drought *** results suggest that the adverse effects of drought can be minimized by applying melatonin to apples.

关键词： Apple Chlorophyll fluorescence Drought Melatonin Photosynthesis

A finite element modeling of posterior atlantoaxial fixation and biomechanical analysis of C2 intralaminar screw fixation

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Chinese Medical Journal 2014年第7期127卷 1266-1271页

作者： Ma Xuexiao Peng xianbo Xiang Hongfei zhang Yan zhang Guoqing Chen Bohua Department of Orthopaedic Surgery the Affiliated Hospital of Qingdao University Qingdao Shandong 266003 China

Background The objective of this study was to use three-dimensional finite element （FE） models to analyze the stability and the biomechanics of two upper cervical fixation methods：the C2 intralaminar screw method and the C2 pedicle screw *** From computed tomography images,a nonlinear three-dimensional FE model from C0 （occiput） to C3 was developed with anatomic *** C2 intralaminar screw and the C2 pedicle screw systems were added to the model,in parallel to establish the interlaminar model and the pedicle *** two models were operated with all possible states of motion and physiological loads to simulate normal *** Both the C2 intralaminar screw method and the C2 pedicle screw method significantly reduced motion compared with the intact *** were no statistically significant differences between the two *** Von Mises stresses of the internal and external laminar walls were similar between the two *** was also *** The C2 intralaminar screw method can complement but cannot completely replace the C2 pedicle screw *** would need to assess and decide which approach to adopt for the best therapeutic effect.

关键词： finite elements upper cervical spine intralaminar screw pedicle screw biomechanics

Synthesis and Thermodynamic Properties of M2L[M=Li, Na; L=3,6-Bis（1H-1,2,3,4-tetrazol-5-yl-amino）-1,2,4,5-tetrazine]

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Chemical Research in Chinese Universities 2018年第2期34卷 254-259页

作者： zhang Wenhui LIU Qing REN Yinghui YANG Bin zhang xianbo zhang Chao MA Haixia ZHAO Fengqi HU Rongzu Department of Chemical Engineering Northwest University Xi'an 710069 R R. China Xi'an Modern Chemistry Research Institute Xi'an 710065 P. R. China

Two novel energetic alkalic metal salts of 3,6-bis（1H-1,2,3,4-tetrazol-5-yl-amino）-l,2,4,5-tetrazine （BTATz）, Li2（BTATz）. 6H20（compound 1） and Na2（BTATz）. 2H20（compound 2）, have been synthesized by the reac- tion of BTATz with lithinnl hydroxide or sodium hydroxide in dimethylsulfoxide（DMSO） solution, respectively, and their structures were characterized by means of elemental analysis and Fourier transform infrared spectrometry（FTIR） Moreover, the single-crystal structure of compound 1 was determined by single crystal X-ray diffraction. It crystal- lizes in the monoclinic space group P1/c. Furthermore, their thermal decomposition behaviors were investigated by means of differential scanning calorimetry（DSC） and thermogravimetry-differential thermal gravimetry（TG-DTG）. The results show that the exothermic decomposition peak temperatures for compounds 1 and 2 were 642.65 and 644.46 K, respectively, and the kinetic equations of the main exothermic decomposition were also derived from non-isothermal method. Additionally, the thermal safety of the two compounds was evaluated by calculating self-accelerating decomposition temperature（TSADT） and critical temperature of thermal explosion（Tb）. The results（the TSADT and Tb values are 605.43 and 635.69 K for compound 1; 607.38 and 638.96 K for compound 2） reveal that the two compounds exhibit better thermal safety than BTATz.

关键词： 3,6-Bis(1H-1,2,3,4-tetrazol-5-yl-mnino)-l,2,4,5-tetrazine(BTATz) Alkalic metal salt Thermal behavior Thermodynamic property Thermal safety

EBZ-260综掘机在大断面岩巷掘进中的应用

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煤炭与化工 2022年第3期45卷 35-37页

作者：张献波晋能控股煤业集团晋中公司山西晋中030600

为提高岩巷掘进速度,紫金煤矿在6煤回风下山进行了综掘机施工的实验。在分析传统钻爆法施工存在问题的基础上,确定采用EBZ-260综掘机,建立1套以岩巷综掘机为主配套的快速掘进作业线。现场应用表明,最高日进尺达到8 m,月进尺在150 m以上... 详细信息

为提高岩巷掘进速度,紫金煤矿在6煤回风下山进行了综掘机施工的实验。在分析传统钻爆法施工存在问题的基础上,确定采用EBZ-260综掘机,建立1套以岩巷综掘机为主配套的快速掘进作业线。现场应用表明,最高日进尺达到8 m,月进尺在150 m以上,是炮掘速度的2倍,降低了工人的劳动强度,提高了安全系数,取得了较好的经济和社会效益,具有广阔的推广应用前景。

关键词：综掘机钻爆法设备配套安全系数

高倍数水驱砂岩中原油黏度、岩心润湿性时变规律核磁共振实验

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石油勘探与开发 2024年第2期51卷 348-355页

作者：贾虎张瑞罗宪波周子力杨璐西南石油大学油气藏地质及开发工程全国重点实验室成都610500 中海油田服务股份有限公司天津300459 中海石油(中国)有限公司天津分公司天津300459

根据模拟原油黏度与横向弛豫时间谱几何平均值的变化关系,建立了模拟原油黏度预测模型,并结合高倍数水驱核磁共振(NMR)实验实现了孔隙介质中模拟原油黏度的时变规律定量表征;基于核磁共振弛豫理论推导出新的NMR润湿性指数计算公式,结合... 详细信息

根据模拟原油黏度与横向弛豫时间谱几何平均值的变化关系,建立了模拟原油黏度预测模型,并结合高倍数水驱核磁共振(NMR)实验实现了孔隙介质中模拟原油黏度的时变规律定量表征;基于核磁共振弛豫理论推导出新的NMR润湿性指数计算公式,结合砂岩岩心高倍数水驱实验,定量表征了水驱过程岩石润湿性的时变规律。研究表明:岩心中剩余油黏度与过水倍数正相关,过水倍数较低时剩余油黏度升高速度较快,过水倍数较高时剩余油黏度升高速度趋缓。剩余油黏度的变化与储层非均质性相关,储层均质性越强,剩余油中重质组分含量越高,黏度越高。注水后储层润湿性将发生改变,亲油储层向亲水储层转变,亲水储层则亲水性更强,且改变程度随过水倍数增加而增强。原油黏度的时变性与润湿性的时变性具有很高的关联性,原油的黏度变化不可忽略,考虑模拟原油黏度变化时计算得到NMR润湿性指数与测试Amott(自吸法)润湿性指数更具有一致性,更加符合储层润湿性时变规律。

关键词：砂岩高倍数水驱核磁共振原油黏度岩石润湿性时变规律

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体力活动/运动与癌症防治:研究与应用

成都体育学院学报 2022年第6期48卷 1-7,23页

作者：王正珍王娟张献博徐峻华北京体育大学北京100084 北京医院内分泌科国家老年医学中心中国医学科学院老年医学研究院北京100730 运动是良医(北京)健康技术研究院北京100086

体力活动/运动是所有年龄段和不同身体活动水平人群预防、治疗和控制癌症最重要的方法之一。近10年来运动肿瘤学得到了快速发展。大量研究表明,体力活动/运动在癌症预防、增强治疗效果、缓解治疗毒副作用,以及延缓转移和延长患者寿命方... 详细信息

体力活动/运动是所有年龄段和不同身体活动水平人群预防、治疗和控制癌症最重要的方法之一。近10年来运动肿瘤学得到了快速发展。大量研究表明,体力活动/运动在癌症预防、增强治疗效果、缓解治疗毒副作用,以及延缓转移和延长患者寿命方面有明确的作用。按照世界卫生组织的体力活动推荐可以有效地预防常见癌症,多数癌症生存者可以遵循世卫组织的推荐进行运动,但是鉴于癌症的复杂性和对人体的影响,多数癌症生存者按照运动处方运动会更加安全有效。主流医学界和患者应该充分了解体力活动/运动防治癌症的重要意义,努力将运动处方作为癌症预防和治疗范式的标准部分,使更多的患者从中受益。

关键词：体力活动/身体活动运动运动肿瘤学运动处方癌症生存者运动康复

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原发乙状结肠鳞状细胞癌1例并文献复习

肿瘤研究与临床 2023年第2期35卷 141-143页

作者：许帅杜东杰邱刚康林张献波张明河北省人民医院肿瘤科石家庄050051 河北省人民医院病理科石家庄050051

目的提高对晚期原发乙状结肠鳞状细胞癌诊断和治疗的认识。方法回顾性分析河北省人民医院2020年10月收治的1例男性晚期原发乙状结肠鳞状细胞癌伴左侧髂血管旁转移患者的临床资料,并进行文献复习。结果患者原发乙状结肠鳞状细胞癌术后残... 详细信息

目的提高对晚期原发乙状结肠鳞状细胞癌诊断和治疗的认识。方法回顾性分析河北省人民医院2020年10月收治的1例男性晚期原发乙状结肠鳞状细胞癌伴左侧髂血管旁转移患者的临床资料,并进行文献复习。结果患者原发乙状结肠鳞状细胞癌术后残留左侧髂血管旁转移灶。术后1个月给予盆腔淋巴结引流区及左侧髂血管旁转移灶放疗,同步行白蛋白结合型紫杉醇联合顺铂方案化疗。综合治疗后疗效评价为疾病稳定。随访截至2022年8月,患者无进展生存达22个月。结论原发结肠鳞状细胞癌较罕见,治疗首选手术切除,术后应根据病情行个体化全程管理。对于转移患者除全身治疗外应尽早联合局部治疗。

关键词：乙状结肠肿瘤癌,鳞状细胞放射治疗药物疗法,联合

N-doped graphene quantum dot-decorated N-TiO2/P-doped porous hollow g-C_(3)N_(4) nanotube composite photocatalysts for antibiotic photodegradation and H2 production

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International Journal of Minerals,Metallurgy and Materials 2024年第1期31卷 165-178页

作者： Jingshu Yuan Yao zhang Xiaoyan zhang Junjie zhang Shen’gen zhang Institute for Advanced Materials and Technology University of Science and Technology BeijingBeijing 100083China Xi’an Fanyi University Xi’an 710105China Shunde Graduate School of University of Science and Technology Beijing Foshan 528399China State Key Laboratory of Lunar and Planetary Sciences Macao University of Science and TechnologyMacao SAR 820000China

Exclusive responsiveness to ultraviolet light (~3.2 eV) and high photogenerated charge recombination rate are the two primary drawbacks of pure TiO_(2). We combined N-doped graphene quantum dots (N-GQDs), morphology regulation, and heterojunction construction strategies to synthesize N-GQD/N-doped TiO_(2)/P-doped porous hollow g-C_(3)N_(4) nanotube (PCN) composite photocatalysts (denoted as G-TPCN). The optimal sample (G-TPCN doped with 0.1wt% N-GQD, denoted as 0.1% G-TPCN) exhibits significantly enhanced photoabsorption, which is attributed to the change in bandgap caused by elemental doping (P and N), the improved light-harvesting resulting from the tube structure, and the upconversion effect of N-GQDs. In addition, the internal charge separation and transfer capability of0.1% G-TPCN are dramatically boosted, and its carrier concentration is 3.7, 2.3, and 1.9 times that of N-TiO_(2), PCN, and N-TiO_(2)/PCN(TPCN-1), respectively. This phenomenon is attributed to the formation of Z-scheme heterojunction between N-TiO_(2) and PCNs, the excellent electron conduction ability of N-GQDs, and the short transfer distance caused by the porous nanotube structure. Compared with those of N-TiO_(2), PCNs, and TPCN-1, the H2 production activity of 0.1%G-TPCN under visible light is enhanced by 12.4, 2.3, and 1.4times, respectively, and its ciprofloxacin (CIP) degradation rate is increased by 7.9, 5.7, and 2.9 times, respectively. The optimized performance benefits from excellent photoresponsiveness and improved carrier separation and migration efficiencies. Finally, the photocatalytic mechanism of 0.1% G-TPCN and five possible degradation pathways of CIP are proposed. This study clarifies the mechanism of multiple modification strategies to synergistically improve the photocatalytic performance of 0.1% G-TPCN and provides a potential strategy for rationally designing novel photocatalysts for environmental remediation and solar energy conversion.

关键词： N-doped TiO_(2) N-doped graphene quantum dots P-doped g-C_(3)N_(4) porous hollow nanotube heterojunction photocatalysis