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A micro amperometric immunosensor for detection of human immunoglobulin

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Science in China(Series F) 2006年第3期49卷 397-408页

作者： XU yuanyuan xia Shanhong BIAN Chao CHEN Shaofeng State Key Laboratory of Transducer Technology Institute of Electronics Chinese Academy of SciencesBeijing 100080 China

A novel amperometric immunosensor based on the micro electromechanical systems （MEMS） technology, using protein A and self-assembled monolayers （SAMs） for the orientation-controlled immobilization of antibodies, has been developed. Using MEMS technology, an ＂Au, Pt, Pt＂ three-microelectrode system enclosed in a SU-8 micro pool was fabricated. Employing SAMs, a monolayer of protein A was immobilized on the cysteamine modified Au electrode to achieve the orientation-controlled immobilization of the human immunoglobulin （HIgG） antibody. The immunosensor aimed at low unit cost, small dimension, high level of integration and the prospect of a biosensor system-on-a-chip. Cyclic voltammetry and chronoamperometry were conducted to characterize the immunosensor. Compared with the traditional immunosensor using bulky gold electrode or screen-printed electrode and the procedure directly binding protein A to electrode for immobilization of antibodies, it had attractive advantages, such as miniaturization, compatibility with CMOS technology, fast response （30 s）, broad linear range （50-400 pg/L） and low detection limit （10 pg/L） for HIgG. In addition, this immunosensor was easy to be designed into micro array and to realize the simultaneously multi-parameter detection.

关键词： amperometric immunosensor micro electromechanical systems (MEMS) self-assembled monolay-ers (SAMs) protein A orientation-controlled immobilization biosensor system-on-a-chip.

Gas template-assisted spray pyrolysis： A facile strategy to produce porous hollow Co3O4 with tunable porosity for high-performance lithium-ion battery anode materials

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Nano Research 2018年第3期11卷 1490-1499页

作者： Haoran Du Kuangfu Huang Min Li yuanyuan xia Yixuan Sun Mengkang Yu Baoyou Geng College of Chemistry and Materials Science Anhui Key Laboratory of Functional Molecular Solids Ministry of Education Anhui Laboratory of Molecular-Based Materials Center for Nano-Science and Technology Anhui Normal University Wuhu 241000 China

Porous hollow Co3O4 microspheres have been synthesized from a mixed cobalt nitrate and urea solution through spray pyrolysis followed by calcination at 600 ℃ in air. This porous hollow Co3O4 is assembled by nanoparticles and exhibits variable porosity depending on the amount of gas in the system. In pyrolysis process, urea continuously decomposes into gaseous components, which act as a template to control the porous structure. The amount of gas escaping from precursor droplets can directly influence the porosity of the microspheres and the size of the nanoparticles controlled by the ratio of urea to cobalt nitrate. Electrochemical measurements show that the performance of the porous hollow Co3O4 microspheres is related to the porosity and size of the nanopartides. The sample with optimal porosity delivers a high first charge capacity of 1,417.9 mAh·g^-1 at 0.2C （1C = 890 mA·g^-1）, and superior charge cycle performance of 1,012.7 mAh.g-1 after 100 cycles. In addition, the optimized material displays satisfactory rate performance of 1,012.4 mAh.g-1 at 1C after 50 cycles and 881.3 mAh·g^-1 at 2C after 300 cycles. Superior charge/discharge capacity, excellent rate performance and high yield achieved in this study is promising for the development of high-performance Co3O4 anode materials for lithium-ion batteries.

关键词： Co3O4/gas template tunable porosity spray pyrolysis anode lithium-ion batteries

Seepage-Stress-Damage Coupled Model of Coal Under Geo-Stress Influence

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Computers, Materials & Continua 2018年第1期54卷 43-59页

作者： Yi Xue Faning Dang Rongjian Li Liuming Fan Qin Hao Lin Mu yuanyuan xia State Key Laboratory Base of Eco-Hydraulic Engineering in Arid Areas Xi’an University of TechnologyXi’an 710048China Institute of Geotechnical Engineering Shaanxi Provincial Key Laboratory of Loess Mechanics and EngineeringXi’an University of TechnologyXi’an 710048China Department of Civil Engineering Henan Vocational College of Water Conservancy and EnvironmentZhengzhou 450011China

In the seepage-stress-damage coupled process,the mechanical properties and seepage characteristics of coal are distinctly different between pre-peak stage and post-peak *** difference is mainly caused by damage of ***,in the process of seepage and stress analysis of coal under the influence of excavation or mining,we need to consider the weakening of mechanical properties and the development of fractures of damaged *** on this understanding,this paper analyzes the influence of damage on mechanics and seepage behavior of coal.A coupled model is established to analyze the seepage-stress-damage coupled process of *** model implemented into COMSOL and MATLAB software to realize the numerical *** examples are adopted to verify the correctness of the model and some useful conclusions are *** numerical model establishes the relationship between microcosmic damage evolution and macroscopical fracture and simulates the whole process of coal from microcosmic damage to macroscopical fracture,and the dynamic simulation of fluid flow in this *** provides a numerical tool for further research on the seepage-stress-damage analysis.

关键词： Permeability porosity gas pressure damage coupled model

Unprecedented Glory Over the past century,the Communist Party of China has Ied the people to liberation and prosperity

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ChinAfrica 2021年第7期13卷 12-17页

作者： xia yuanyuan 不详

It is the second time for Ahcene Boukhelfa to visit the Nanhu Lake in Jiaxing,east China's Zhejiang Province,to take a look at the red boat,one of the most iconic sites to record the history of the Communist Party of China(CPC)."It's like visiting an old friend,"the Algerian Ambassador to China *** his visit on June 9 had special meaning as it came ahead of the 100th anniversary of the founding of the CPC.

关键词： founding Communist visit

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Epic Space Voyage

ChinAfrica 2022年第7期14卷 22-27页

作者： xia yuanyuan 不详

The 18th National Congress of the Communist Party of China held in 2012 marked a great milestone in modern China. In this section, we take a look at the achievements in various fields to understand the significance of... 详细信息

关键词： China Communist witnessed

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AVALLEY OF VITALITY

Beijing Review 2024年第23期67卷 16-17页

作者： xia yuanyuan 不详

The medical equipment valley in Jiading District of Shanghai,known as Shanghai MedValley,is a powerhouse of medical *** an industrial park centered on creative medical equipment,the valley has gathered a cluster of hi... 详细信息

关键词： valley enterprises cluster

Yundang Lake Gets Epic Facelift

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China Today 2024年第1期73卷 56-58页

作者： xia yuanyuan 不详

The transformation of Yundang Lake from a stinky lake to an urban reception hall has made it a showcase of ecologival restoration in *** settling down in the City of xiamen,Scott Patrick and his wife spent long hours searching online for just the right part of the *** they saw Yundang Lake in west xiamen,the couple knew they had hit the jackpot.“The picture of the beautiful lake circled by lush vegetation caught our *** knew this was the place we were looking for,”said ***,after setting foot in xiamen,he told himself he had definitely made the right life decision.

关键词： xiamen settling looking

Building an Immune Barrier

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ChinAfrica 2021年第3期13卷 20-21页

作者： xia yuanyuan 不详

Chinese vaccines help the global fight against COVID-19 pandemic Wang Jiansheng,a taxi driver with Beifang Autos Renting *** Beijing,is one of the first Chinese residents to receive free vaccination for COVID-19 after... 详细信息

关键词： residents campaign fight

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Driven by Knowledge

ChinAfrica 2022年第9期14卷 14-16页

作者： xia yuanyuan 不详

Think tanks offer ideas contributing to improving communication and mutual understanding, and enhancing cooperation between China and Africa More than 200 attendees including officials and scholars from China and Africa participated in the 11th Meeting of the ChinaAfrica Think Tanks Forum(CATTF), held both online and offline from July 20 to 21, to enhance the deep understanding between the two sides.

关键词： mutual Africa officials