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Gastrointestinal contrast-enhanced ultrasonography for diagnosis and treatment of peptic ulcer in children

World Journal of Gastroenterology 2024年第7期30卷 705-713页

作者： yu-Hua Zhang Zhi-Hua Xu Shuang-Shuang Ni Hong-xia Luo Department of Ultrasound The Second Affiliated Hospital of Wenzhou Medical UniversityWenzhou 325000Zhejiang ProvinceChina

BACKGROUND The detection rate of peptic ulcer in children is improving,with development of diagnostic *** is the gold standard for the diagnosis of peptic ulcer,but it is an invasive *** contrast-enhanced ultrasonography(CEUS)has the advantages of being painless,noninvasive,nonradioactive,easy to use,and *** To investigate the clinical value of CEUS for diagnosis and treatment of peptic ulcer in *** We investigated 43 children with digestive tract symptoms in our hospital from January 2021 to June *** children were examined by routine ultrasound,gastrointestinal CEUS,and *** pathological results of gastroscopy were taken as the gold *** ultrasonography was performed before gastrointestinal *** ultrasound showed the thickness of the gastroduodenal wall,gastric peristalsis,and the adjacent organs and tissues around the abdominal *** CEUS recorded the thickness of the gastroduodenal wall;the size,location and shape of the ulcer;gastric peristalsis;and adjacent organs and tissues around the abdominal *** results of routine ultrasound and gastrointestinal ultrasound were compared with those of gastroscopy to evaluate the diagnostic results and coincidence rate of routine ultrasound and gastrointestinal *** children received informed consent from their guardians for *** study was reviewed and approved by the hospital medical ethics *** Among the 43 children,17(15 male,2 female)were diagnosed with peptic ulcer by *** were 26 children with nonpeptic *** were eight cases of peptic ulcer and 35 of nonpeptic ulcer diagnosed by conventional *** diagnostic coincidence rate of peptic ulcer in children diagnosed by conventional ultrasound was 79.1%(34/43),which was significantly different from that of gastroscopy(P=0.033).It indicates that the coincidence rate of gastrointestinal contrast-enhanc

关键词： Contrast-enhanced ultrasound Peptic ulcer Children Gastrointestinal tract Abdominal pain Acoustic contrast agent

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Idiopathic mesenteric phlebosclerosis missed by a radiologist at initial diagnosis: A case report

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World Journal of Clinical Cases 2024年第10期12卷 1810-1816页

作者： Min Wang yu-xia Wan Jin-Wen Liao Fei Xiong Department of Gastroenterology Changning County People’s HospitalYibin 644300Sichuan ProvinceChina Department of Gastroenterology Qianwei People’s HospitalLeshan 614400Sichuan ProvinceChina Department of Gastroenterology The People’s Hospital of Jianyang CityChengdu 641400Sichuan ProvinceChina Department of Gastroenterology Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengdu 610000Sichuan ProvinceChina

BACKGROUND Idiopathic mesenteric phlebosclerosis(IMP)is a rare type of ischemic colitis characterized by thickening of the wall of the right hemicolon and calcification,sclerosis,and fibrosis of mesenteric *** diagnosis of IMP is based on typical clinical features and imaging *** report a case of IMP that was initially missed by the *** SUMMARY A 77-year-old woman was admitted to the hospital due to chronic diarrhea for over 2 *** had been consuming Chinese patent medicines(CPM)containing fructus gardeniae for more than 15 *** revealed an edematous mucosa,bluish-purple discoloration,erosions,and ulcerations throughout the colorectal *** computed tomography(CT)showed diffuse mural thickening of the entire colorectum,with tortuous thread-like calcifications in the right hemicolon,left hemicolon,and *** of the calcifications were located in the mesenteric *** diagnosis of IMP was established based on medical history,colonoscopy,CT findings,and histopathological *** patient was treated conservatively with papaverine and rifaximin,and CPM was *** diarrhea symptoms improved,indicating the effectiveness of the *** the next several years,she took opium alkaloids for an extended period and did not require hospitalization for the aforementioned gastrointestinal *** IMP is a rare gastrointestinal disease affecting Asian populations,possibly related to long-term herbal medicine *** imaging analysis is crucial for diagnosis,but insufficient understanding of the disease can lead to misdiagnosis or missed *** strategies should be personalized.

关键词： Idiopathic mesenteric phlebosclerosis Computed tomography Colonoscopy Chinese patent medicines Fructus gardeniae Case report

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Progress on gas-solid phase photoreactor and its application in CO2 reduction

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Green Chemical Engineering 2024年第3期5卷 290-306页

作者： Litian Liu yunlong Li Jialun He Qing Wang juan Deng xiao Chen Chao yu School of Environmental and Chemical Engineering Jiangsu University of Science and Technology

The burgeoning field of photocatalytic reduction of CO2has emerged as a remarkable promising solution to address some of the most pressing global energy and environmental issues which we face today. Researchers around the global have been striving to augment the efficiency of CO2photocatalytic reduction, employing strategies that range from modifying the fundamental properties of photocatalysts to suppress the electron-hole recombination, optimizing reaction conditions to achieve the highest yield, and conceptualizing and constructing photoreactors to improve the adsorption process. Among these factors, the photoreactor plays a critical role in enhancing the overall photocatalytic efficiency. Understanding the various types of photoreactors and their operational dynamic can significantly influence the experimental design, thus guiding the data collecting and analysis. Compared to the solid-liquid phase, gas-solid phase photocatalytic reduction of CO2is gaining recognition for its potential advantages, such as rapid molecular diffusion rates, adjustable CO2concentrations, and uniform and sufficient light exposure. Nonetheless, the currently reported gas-solid phase photoreactors are still in their infancy. In this review, we dissect the underlying mechanism of photocatalytic CO2reduction and the performance evaluation criteria of photoreactors, and review the development process of gas-solid phase photoreactors. Furthermore, we explore the evolution of gas-solid phase photoreactors, elucidating their growth trajectory and future possibilities. We present a comprehensive classification of gas-solid phase photoreactors,offering a new insight into their design and functionality, summarizing their strengths and inevitable ***, we provide a forward-looking perspective on the future developmental prospects of carbon neutrality.

关键词： Photoreactor Gas-solid phase Carbon dioxide reduction Photocatalysis

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Chemotherapy combined with bevacizumab for small cell lung cancer with brain metastases:A case report

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World Journal of Clinical Cases 2024年第2期12卷 405-411页

作者： Hong-yu Yang yu-Qing xia yu-Jia Hou Peng Xue Shi-Jie Zhu Dian-Rong Lu Department of Oncology Wangjing HospitalChina Academy of Chinese Medical SciencesBeijing 100102China Department of Oncology Tianjin University of Chinese MedicineTianjin 300000China Department of Electrothermal Acupuncture Wangjing HospitalChina Academy of Chinese Medical SciencesBeijing 100102China Department of Acupuncture and Moxibustion Sihui Hospital of Traditional Chinese MedicineBeijing 100102China

BACKGROUND Small cell lung cancer(SCLC)is a common and aggressive subtype of lung *** is characterized by rapid growth and a high mortality *** 10%of patients with SCLC present with brain metastases at the time of diagnosis,which is associated with a median survival of 5 *** study aimed to summarize the effect of bevacizumab on the progression-free survival(PFS)and overall survival of patients with brain metastasis of *** SUMMARY A 62-year-old man was referred to our hospital in February 2023 because of dizziness and numbness of the right lower extremity without headache or fever for more than four *** patient was diagnosed with limited-stage *** received 8 cycles of chemotherapy combined with maintenance bevacizumab therapy and achieved a PFS of over 7 *** The combination of bevacizumab and irinotecan effectively alleviated brain metastasis in SCLC and prolonged PFS.

关键词： Small cell lung cancer Bevacizumab Brain metastasis Antineoplastic agents Target therapies Immunotherapy Radiotherapy Case report

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Research progress of permanent ferrite magnet materials

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Journal of Central South University 2024年第6期31卷 1723-1762页

作者： XU Bin CHEN yu-feng ZHOU yu-juan LUO Bi-yun ZHONG Shou-guo LIU Xing-ao School of Minerals Processing and Bioengineering Central South UniversityChangsha 410083China

Permanent ferrite magnet materials are extensively employed due to their exceptional magnetic properties and *** fast development in electromobile and household appliance industries contributes to a new progress in permanent ferrite *** paper reviews the deveolpement and progress of permanent ferrite magnet industry in recent *** emergence of new raw material,the advancement of perparation methods and manufacturing techniques,and the potential applications of permanent ferrite materials are introduced and ***,nanocrystallization plays a crucial role in achieving high performance at a low cost and reducing reliance on rare earth resources,and therefore it could be a promising development trendency.

关键词： permanent ferrite magnetic materials high-performance nanosizing

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Construction of MnS/MoS_(2) heterostructure on two-dimensional MoS_(2) surface to regulate the reaction pathways for high-performance Li-O_(2) batteries

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Journal of Energy Chemistry 2024年第6期93卷 443-452,I0012页

作者： Guoliang Zhang Han yu xia Li Xiuqi Zhang Chuanxin Hou Shuhui Sun Yong Du Zhanhu Guo Feng Dang Key Laboratory for Liquid-Solid Structure Evolution and.Processing of Materials(Ministry of Education) Shandong UniversityJinan 250061ShandongChina School of Environmental and Material Engineering Yantai UniversityYantai 264005ShandongChina Institute National de la Recherche Scientifique CentreÉnergie Matériaux et TélécommunicationsVarennesQuébec J31S2Canada State Key Laboratory of Powder Metallurgy Central South UniversityChangsha 410083HunanChina Integrated Composites Lab Department of Mechanical and Construction EngineeringNorthumbria UniversityNewcastle Upon TyneNE18STUK

The inherent catalytic anisotropy of two-dimensional(2D) materials has limited the enhancement of LiO_(2) batteries(LOBs) performance due to the significantly different adsorption energies on 2D and edge *** the adsorption strength in 2D materials to the reaction intermediates is essential for achieving high-performance ***,a MnS/MoS_(2) heterostructure is designed as a cathode catalyst by adjusting the adsorption behavior at the *** from the toroidal-like discharge products on the MoS_(2) cathode,the MnS/MoS_(2) surface displays an improved adsorption energy to reaction species,thereby promoting the growth of the film-like discharge *** can disturb the layer growth of MoS_(2),in which the stack edge plane features a strong interaction with the intermediates and limits the growth of the discharge *** and theoretical results confirm that the MnS/MoS_(2) heterostructure possesses improved electron transfer kinetics at the interface and plays an important role in the adsorption process for reaction species,which finally affects the morphology of Li_2O_(2),In consequence,the MnS/MoS_(2) heterostructure exhibits a high specific capacity of 11696.0 mA h g^(-1) and good cycle stability over 1800 h with a fixed specific capacity of 600 mA h g^(-1) at current density of100 mA g^(-1) This work provides a novel interfacial engineering strategy to enhance the performance of LOBs by tuning the adsorption properties of 2D materials.

关键词： Li-O_(2)batteries Two-dimensional materials MnS/MoS_(2)heterostructure Edge plane Adsorption behavior

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Design and experiment of anti-adhesion rototiller based on staggered double-roller scraping

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International Journal of Agricultural and Biological Engineering 2024年第4期17卷 165-175页

作者： Jian Cheng Junfang xia Kan Zheng Guoyang Liu Youshuai Wei juan Zou College of Engineering Huazhong Agricultural UniversityWuhan 430070China Key Laboratory of Agricultural Equipment in Mid-lower Reaches of Yangtze River Ministry of Agriculture and Rural AffairsWuhan 430070China Hubei academy of agricultural sciences institute of food crops Wuhan 430070China

In order to solve the serious problem of soil adhering blade roller in the middle and lower reaches of Yangtze River,the anti-adhesion rototiller based on staggered double-roller scraping(ARSDS)was designed by mechanical scraping *** volume equation for scraping the soil adhesion part with staggered rotary blades was *** mechanical conditions for separation of soil adhesion part from blade roller were clarified,and the contact time between rotary blade and soil during rotary tillage was *** this way,the key parameters affecting soil adhering on and separating from the blade roller were determined,which were rotational speed,cutting pitch and tillage *** spatial and temporal trajectory changes for the sidelong section edge of staggered rotary blades were analyzed,so that the rotary blade arrangement was *** the discrete element method,selecting the soil adhesion mass on the staggered blade rollers as the response value established prediction model by Box-Behnken design *** example,taking the tillage depth of 14 cm for wheat cultivation in the middle and lower reaches of Yangtze River,the optimal combination of parameters was determined to be 230 r/min and 10 cm for rotational speed and cutting pitch,*** this time,the soil adhesion mass was 4566.67 *** the meantime,the process of soil particles adhering staggered blade rollers and rotary blades scraping off the adhering soil were *** experiments have shown that the operation quality of ARSDS met the requirements of rototiller performance *** the rice stubble field of high water moisture,the soil adhesion mass was 13.455 kg and 38.215 kg for ARSDS and conventional rototiller,respectively,which indicated that ARSDS effectively reducing soil adhesion *** research results can provide technical support for the design of rototiller reducing soil adhesion in the agricultural areas of the middle and lower reaches of the Yangtze River.

关键词： rice stubble field rotary tillage reducing soil adhesion staggered double-roller discrete element method

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Role of micro-Ca/In alloying in tailoring the microstructural characteristics and discharge performance of dilute Mg-Bi-Sn-based alloys as anodes for Mg-air batteries

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Journal of Magnesium and Alloys 2024年第1期12卷 251-266页

作者： Fei-er Shangguan Wei-li Cheng yu-hang Chen Ze-qin Cui Hui yu Hong-xia Wang Li-fei Wang Hang Li Hua Hou School of Materials Science and Engineering Taiyuan University of TechnologyTaiyuan 030024China School of Materials Science and Engineering Hebei University of TechnologyTianjin 300132China School of Materials Science and Engineering North University of ChinaTaiyuan 030051China

The influence of micro-Ca/In alloying on the microstructural charac teristics,electrochemical behaviors and discharge properties of extruded dilute Mg-0.5Bi-0.5Sn-based(wt.%)alloys as anodes for Mg-air batteries are *** grain size and texture intensity of the Mg-Bi-Sn-based alloys are significantly decreased after the Ca/In alloying,particularly for the In-containing *** that,in addition to nanoscale Mg_(3)Bi_(2)phase,a new microscale Mg_(2)Bi_(2)Ca phase forms in the Ca-containing *** electrochemical test results demonstrate that Ca/In micro-alloying can enhance the electrochemical *** In to alloy the Mg-Bi-Sn-based alloy is effective in restricting the cathodic hydrogen evolution(CHE)kinetics,leading to a low self-corrosion rate,while severe CHE occurred after Ca *** micro-alloying of Ca/In to Mg-Bi-Sn-based alloy strongly deteriorates the compactness of discharge products film and mitigates the"chunk effect"(CE),hence the cell voltage,anodic efficiency as well as discharge capacity are greatly *** In-containing alloy exhibits outstanding discharge performance under the combined effect of the modified microstructure and discharge products,thus making it a potential anode material for primary Mg-air battery.

关键词： Mg-air batteries Mg-Bi-Sn based alloys Electrochemical behaviors Discharge properties

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Role of inflammatory lipid and fatty acid metabolic abnormalities induced by plastic additives exposure in childhood asthma

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Journal of Environmental Sciences 2024年第3期137卷 172-180页

作者： Zhiyu Chen Fang Li Lei Fu yu xia Ying Luo Ang Guo xiaona Zhu Huifang Zhong Qian Luo Institute of Biomedical and Health Engineering Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China University of Chinese Academy of Sciences Beijing 100049China Rheumatology&Immunology Department of Shenzhen Children’s Hospital Shenzhen 518038China Hubei Key Laboratory of Environmental and Health Effects of Persistent Toxic Substances Institute of Environment and HealthJianghan UniversityWuhan 430056China

Lipid metabolism play an essential role in occurrence and development of asthma,and it can be disturbed by phthalate esters(PAEs)and organophosphate fame retardants(OPFRs).As a chronic infammatory respiratory disease,the occurrence risk of childhood asthma is increased by PAEs and OPFRs exposure,but it remains not entirely clear how PAEs and OPFRs contribute the onset and progress of the *** have profiled the serum levels of PAEs and OPFRs congeners by liquid chromatography coupled with mass spectrometry,and its relationships with the dysregulation of lipid metabolism in asthmatic,bronchitic(acute infammation)and healthy(non-infammation)*** PAEs and nine OPFRs congeners were found in the serum of children(1–5 years old)from Shenzhen,and their total median levels were 615.16 ng/m L and 17.06 ng/m L,***,the serum levels of mono-methyl phthalate(MMP),tri-propyl phosphate(TPP)and tri-n-butyl phosphate(TNBP)were significant higher in asthmatic children than in healthy and bronchitic children as ***-one characteristic lipids and fatty acids of asthma were screened by machine-learning random forest model based on serum lipidome data,and the alterations of infammatory characteristic lipids and fatty acids including palmitic acids,12,13-Di HODE,14,21-Di HDHA,prostaglandin D2 and Lyso PA(18:2)showed significant correlated with high serum levels of MMP,TPP and *** results imply PAEs and OPFRs promote the occurrence of childhood asthma via disrupting infammatory lipid and fatty acid metabolism,and provide a novel sight for better understanding the effects of plastic additives on childhood asthma.

关键词： Phthalate esters Organophosphate fame retardants Childhood asthma Lipid and fatty acid metabolism Machine-learning random forest model Chronic airway infammation

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Machine learning and bioinformatics to identify biomarkers in response to Burkholderia pseudomallei infection in mice

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BIOCELL 2024年第4期48卷 613-621页

作者： YAO FANG FEI xia FEIFEI TIAN L EI QU FANG YANG juan FANG ZHENHONG HU HAICHAO LIU Department of Respiratory and Critical Care Medicine General Hospital of Center Theater of PLAWuhan430070China School of Medicine Wuhan University of Science and TechnologyWuhan430065China School of Life Science and Engineering Southwest Jiaotong UniversityChengdu611756China

Objective:In the realm of Class I pathogens,Burkholderia pseudomallei(BP)stands out for its propensity to induce severe *** the intricate interactions between BP and host cells is imperative for comprehending the dynamics of BP infection and discerning biomarkers indicative of the host cell response ***:mRNA extraction from BP-infected mouse macrophages constituted the initial step of our *** gene expression arrays,the extracted RNA underwent conversion into digital *** percentile shift method facilitated data processing,with the identiﬁcation of genes manifesting signiﬁcant differences accomplished through the application of the ***,a comprehensive analysis involving Gene Ontology enrichment and Kyoto Encyclopedia of Genes and Genomes pathway was conducted on the differentially expressed genes(DEGs).Leveraging the ESTIMATE algorithm,gene signatures were utilized to compute risk scores for gene expression *** vector machine analysis and gene enrichment scores were instrumental in establishing correlations between biomarkers and macrophages,followed by an evaluation of the predictive power of the identiﬁed ***:The functional and pathway associations of the DEGs predominantly centered around G protein-coupled receptors.A noteworthy positive correlation emerged between the blue module,consisting of 416 genes,and the ***4,identiﬁed through support vector machine analysis among intersecting genes,indicated a robust interaction with macrophages,suggesting its potential as a robust ***4 exhibited commendable predictive efﬁcacy,with BP infection inducing its expression in both macrophages and mouse lung *** blotting in macrophages conﬁrmed a signiﬁcant upregulation of FZD4 expression from 0.5 to 24 h *** mouse lung tissue,FZD4 manifested higher expression in the cytoplasm of pulmonary epithelial cells in BP-infected lungs than in the

关键词： Burkholderia pseudomallei Microarray assay Machine learning Bioinformatics FZD4

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