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Prevalence, awareness, treatment, and control of hypertension in the non-dialysis chronic kidney disease patients

Chinese Medical Journal 2013年第12期126卷 2276-2280页

作者： zhenG Ying CAI Guang-yan CHEN xiang-mei FU Ping CHEN Jiang-hua DING xiao-qiang yu Xue-qing liN Hong-li liU Jian xiE Ru-juan WANG li-ning NI Zhao-hui liU Fu-you YIN Ai-ping xiNG Chang-ying WANG li SHI Wei liU Jian-she HE Ya-ni DING Guo-hua li wen-ge WU Guang-li MIAO li-ning CHEN Nan SU zhen mei Chang-lin ZHAO Jiu-yang GU Yong BAI yun-kai LUO Hui-min liN Shan CHEN Meng-hua GONG li YANG Yi-bin YANG xiao-ping li Ying WAN Jian-xin WANG Nian-song li Hai-ying xi Chun-sheng HAO li XU Yan FANG Jing-ai liU Bi-cheng li Rong-shan WANG Rong zhang Jing-hong WANG Jian-qin LOU Tan-qi SHAO feng-min mei feng liU Zhi-hong yuAN Wei-jie SUN Shi-ren zhang ling ZHOU Chun-hua CHEN Qin-kai JIA Shun-lian GONG Zhi-feng GUAN Guang-ju xiA Tian ZHONG liang-bao Department of Nephrology State key Laboratory of Kidney Disease Chinese PLA General Hospital Beijing 100853 China Nephrology Institute of the Chinese People's liberation Army Chinese People's Liberation Army Key Laboratory of Nephrology Beijing 100853 China Department of Nephrology West China Hospital of Sichuan University Chengdu Sichuan 610041 China Department of Nephrology First Affiliated Hospital School of Medicine Zhejiang University Hangzhou Zhejiang 310003 China Department of Nephrology Zhongshan Hospital Fudan University Shanghai 200032 China Department of Nephrology First Affiiated Hospital of Sun Yat-sen University Guangzhou Guangdong 510080 China Department of Nephrology First Affiliated Hospital of Dalian Medical University Dalian Liaoning 116011 China Department of Nephrology First Affiliated Hospital of Xinjiang Medical University Urumqi Xinjiang 830054 China Department of Nephrology First Affiliated Hospital of Harbin Medical University Harbin Heilongjiang 150001 China Department of Nephrology First Afftiated Hospital of China Medical University Shenyang Liaoning 110001 China Department of Nephrology Renji Hospital School of Medicine Shanghai Jiao Tong University Shanghai 200025 China Department of Nephrology Second Xiangya Hospital Central South University Changsha Hunan 410000 China Department of Nephrology First Affiliated Hospital of Medical College Xi'an Jiaotong University Xi'an Shaanxi 710061 China Department of Nephrology First Affiliated Hospital of Nanjing Medical University (Jiangsu Province Hospital) Nanjing Jiangsu 210029 China Department of Nephrology Sichuan Provincial People's Hospital Chengdu Sichuan 610072 China Department of Nephrology Guangdong Provincial People's Hospital Guangzhou Guangdong 510030 China Department of Nephrology Affliated Xiehe Hospital Tongji Medical College Huazhong Science and Technology University Wuhan Hubei 430022 China Department of Nephrology Daping Hospital Third Military Medi

Background Data on the epidemiology of hypertension in Chinese non-dialysis chronic kidney disease （CKD） patients are *** aim of the present study was to investigate the prevalence,awareness,treatment,and control of hypertension in the non-dialysis CKD patients through a nationwide,multicenter study in *** The survey was performed in 61 tertiary hospitals in 31 provinces,municipalities,and autonomous regions in China （except Hong Kong,Macao,and Taiwan）.Trained physicians collected demographic and clinical data and measured blood pressure （BP） using a standardized *** was defned as systolic BP ≥140 mmHg and/or diastolic BP ≥90 mmHg,and/or use of antihypertensive *** 〈140/90 mmHg and 〈130/80 mmHg were used as the 2 thresholds of hypertension *** multivariate logistic regression with adjustment for sex and age,we analyzed the association between CKD stages and uncontrolled hypertension in non-dialysis CKD *** The analysis included 8927 non-dialysis CKD *** prevalence,awareness,and treatment of hypertension in non-dialysis CKD patients were 67.3%,85.8%,and 81.0%,*** hypertensive CKD patients,33.1% and 14.1% had controlled BP to 〈140/90 mmHg and 〈130/80 mmHg,*** successive CKD stages,the prevalence of hypertension in non-dialysis CKD patients increased,but the control of hypertension decreased （P〈0.001）.When the threshold of BP 〈130/80 mmHg was considered,the risk of uncontrolled hypertension in CKD 2,3a,3b,4,and 5 stages increased 1.3,1.4,1.4,2.5,and 4.0 times compared with CKD 1 stage,respectively （P〈0.05）.Using the threshold of 〈140/90 mmHg,the risk of uncontrolled hypertension increased in advanced stages （P〈0.05）.Conclusions The prevalence of hypertension Chinese non-dialysis CKD patients was high,and the hypertension control was *** successive CKD stages,the risk of uncontrolled hypertension increased.

关键词： non-dialysis chronic kidney disease chronic kidney disease stages hypertension epidemiology

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Timing analysis of the black hole candidate EXO 1846–031 with Insight-HXMT monitoring

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Research in Astronomy and Astrophysics 2021年第3期21卷 193-204页

作者： He-xin liu yue huang Guang-cheng xiao Qing-Cui Bu Jin-Lu Qu Shu zhang Shuang-Nan zhang Shu-mei Jia Fang-Jun Lu xiang Ma lian Tao Wei zhang li Chen li-Ming Song Ti-Pei li yu-Peng Xu Xue-Lei Cao Yong Chen Cong-Zhan liu Ce Cai Zhi Chang Gang Chen Tian-xiang Chen Yi-Bao Chen yu-Peng Chen Wei Cui Wei-Wei Cui Jing-Kang Deng Yong-Wei Dong yuan-yuan Du Min-Xue Fu Guan-hua Gao He Gao Min Gao Ming-yu Ge yu-Dong Gu Ju Guan cheng-cheng Guo Da-Wei Han Jia Huo Lu-hua Jiang Wei-Chun Jiang Jing Jin Yong-Jie Jin ling-Da Kong Bing li cheng-Kui li Gang li Mao-Shun li Wei li xian li xiao-Bo li Xu-Fang li Yang-Guo li zheng-Wei li xiao-hua liang Jing-yuan liao Bai-Sheng liu Guo-Qing liu Hong-Wei liu xiao-Jing liu Yi-Nong liu Bo Lu Xue-feng Lu Qi Luo Tao Luo Bin Meng Yi Nang Jian-Yin Nie Ge Ou Na Sai Ren-cheng Shang xin-Ying Song liang Sun Ying Tan You-li Tuo Chen Wang Guo-feng Wang Juan Wang ling-Jun Wang weng-Shuai Wang yu-Sa Wang xiang-Yang wen Bai-Yang Wu Bo-Bing Wu mei Wu Shuo xiao Shao-lin xiong He Xu Jia-Wei Yang Sheng Yang Yan-Ji Yang Yi-Jung Yang Qi-Bin Yi Qian-Qing Yin yuan You Ai-mei zhang cheng-Mo zhang Fan zhang Hong-mei zhang Juan zhang Tong zhang Wan-Chang zhang wen-Zhao zhang Yi zhang Yi-Fei zhang Yong-Jie zhang yuan-Hang zhang yue zhang Zhao zhang Zhi zhang Zi-liang zhang Hai-Sheng Zhao xiao-Fan Zhao Shi-Jie zheng Yao-Guang zheng Deng-Ke Zhou Jian-feng Zhou yu-Xuan zhu Ren-lin zhuang yue zhu Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Chinese Academy of SciencesBeijing 100049China Institut fur Astronomie und Astrophysik Kepler Center for Astro and Particle PhysicsEberhard Karls Universität72076 TubingenGermany Department of Astronomy Beijing Normal UniversityBeijing 100088China Department of Astronomy Tsinghua UniversityBeijing 100084China Department of Physics Tsinghua UniversityBeijing 100084China Department of Engineering Physics Tsinghua UniversityBeijing 100084China Key Laboratory of Space Astronomy and Technology National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China College of Physics Sciences&Technology Hebei UniversityBaoding 071002Hebei ProvinceChina

We present the observational results from a detailed timing analysis of the black hole candidate EXO 1846-031 during its outburst in 2019 with the observations of Insight-HXMT,NICER and *** outburst can be classified roughly into four different ***-C quasi-periodic oscillations(QPOs)observed by NICER(about 0.1-6 Hz)and Insight-HXMT(about 0.7-8 Hz)are also reported in this ***,we study various physical quantities related to QPO *** QPO rms-frequency relationship in the energy band 1-10 keV indicates that there is a turning pointing in frequency around2 Hz,which is similar to that of GRS 1915+105.A possible hypothesis for the relationship above may be related to the inclination of the source,which may require a high inclination to explain *** relationships between QPO frequency and QPO rms,hardness,total fractional rms and count rate have also been found in other transient sources,which can indicate that the origin of type-C QPOs is non-thermal.

关键词： X-ray binaries black hole candidate QPO EXO 1846–031

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Structure-Spin-Transport Anomaly in Quasi-One-Dimensional Ba9Fe3Te15 under High Pressure

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Chinese Physics Letters 2020年第8期37卷 101-107页

作者： Jun zhang mei-ling Jin xiang li xian-cheng Wang Jian-Fa Zhao Ying liu Lei Duan wen-Min li li-Peng Cao Bi-Juan Chen li-Juan Wang Fei Sun Yong-Gang Wang liu-xiang Yang yu-Ming xiao zheng Deng Shao-Min feng Chang-Qing Jin Jin-Long zhu Center for High Pressure Science&Technology Advanced Research Beijing 100094China Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China School of Physics University of Chinese Academy of SciencesBeijing 100190China Key Laboratory of Advanced Optoelectronic Quantum Architecture and Measurement(Ministry of Education) School of PhysicsBeijing Institute of TechnologyBeijing 100081China xi'an Modern Chemistry Research Institute Xi'an 710065China High Pressure Collaborative Access Team(HPCAT) Advanced Photon SourceArgonne National LaboratoryArgonneIllinois 60439USA Songshan Lake Materials Laboratory Dongguan 523808China Department of Physics Southern University of Science and TechnologyShenzhen 518055China

Recently,a series of novel compounds Ba3MX5(M=Fe,Ti,V;X=Se,Te)with hexagonal crystal structures composed of quasi-1-dimensional(1D)magnetic chains has been synthesized by our research team using high-pressure and high-temperature *** initial hexagonal phases persist to the maximum achievable pressure,while spin configurations and magnetic interactions may change dramatically as a result of considerable reductions in interchain separations upon *** compounds therefore offer unique possibilities for studying the evolution of intrinsic electronic structures in quasi-1D magnetic *** we present a systematic investigation of Ba9Fe3Te15,in which the interchain separations between trimerized 1D chains(~10.2Å)can be effectively modulated by external high *** crystal structure especially along the 1D chains exhibits an abnormal expansion at^GPa,which accompanies trimerization entangled anomalous mixed-high-low spin *** insulator-metal transition has been observed under high pressure as a result of charge-transfer gap ***-induced superconductivity emerges at 26 GPa,where the charge-transfer gap fully closes,3D electronic configuration forms and local spin fully collapses.

关键词： transition. hexagonal chains

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Metabolic Dysfunction-associated Fatty liver Disease is Associated with Greater Impairment of Lung Function than Nonalcoholic Fatty liver Disease

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Journal of Clinical and Translational Hepatology 2022年第2期10卷 230-237页

作者： Lei Miao li Yang li-Sha Guo Qiang-Qiang Shi Teng-Fei Zhou Yang Chen huai zhang Hui Cai Zhi-Wei Xu Shuan-Ying Yang Hai lin Zhe cheng Ming-Yang zhu Xu Nan Shuai huang Ya-wen zheng Giovanni Targher Christopher D Byrne yu-Ping li Ming-hua zheng cheng-Shui Chen Department of Pulmonary and Critical Care Medicine The First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiangChina Department of Gastroenterology The Second Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiangChina The Interventional Pulmonary Key Laboratory of Zhejiang Province WenzhouZhejiangChina NAFLD Research Center Department of HepatologyThe First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZheji-angChina Department of Biostatistics and Records Room Medical Quality Management OfficeThe First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiangChina Department of Respiratory Medicine Zhong Shan Hospital Affiliated to Shanghai Fudan UniversityShanghaiChina Clinical Research Service Center People’s Hospital of Henan ProvincialZhengzhouHenanChina Department of Respiratory and Critical Care Medicine The Second Affiliated Hospital of Xi’an Jiaotong UniversityXi’anShanxiChina Department of Pulmonary and Critical Care Medicine The Second Affili-ated Hospital of Fujian Medical UniversityQuanzhouFujianChina Department of Pulmonary and Critical Care Medicine The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenanChina Section of Endocrinology Diabetes and MetabolismDepartment of MedicineUniversity and Azienda Ospedaliera Universitaria Integrata of VeronaVeronaItaly Southampton National Institute for Health Research Biomedical Research Center University Hospital SouthamptonSouth-ampton General HospitalSouthamptonUK Key Laboratory of Diagnosis and Treatment for The Development of Chronic liver Disease in Zhejiang Province WenzhouZhejiangChina

Background and Aims:We compared lung function parameters in nonalcoholic fatty liver disease(NAFLD)and metabolic dysfunction-associated fatty liver disease(MAFLD),and examined the association between lung function parameters and fibrosis severity in ***:In this cross-sectional study,we randomly recruited 2,543 middle-aged individuals from 25 communities across four cities in China during 2016 and *** participants received a health check-up including measurement of anthropometric parameters,biochemical variables,liver ultrasonography,and *** severity of liver disease was assessed by the fibrosis(FIB)-4 ***:The prevalence of MAFLD was 20.4%(n=519)and that of NAFLD was 18.4%(n=469).After adjusting for age,sex,adiposity measures,smoking status,and significant alco-hol intake,subjects with MAFLD had a significantly lower predicted forced vital capacity(FVC,88.27±17.60%vs.90.82±16.85%,p<0.05)and lower 1 s forced expiratory volume(FEV1,79.89±17.34 vs.83.02±16.66%,p<0.05)than those with *** with an increased FIB-4 score was significantly associated with decreased lung *** each 1-point increase in FIB-4,FVC was diminished by 0.507(95%CI:-0.840,-0.173,p=0.003),and FEV1 was diminished by 0.439(95%CI:-0.739,-0.140,p=0.004).The results remained unchanged when the statistical analyses was performed separately for men and ***:MAFLD was significantly asso-ciated with a greater impairment of lung function param-eters than NAFLD.

关键词： MAFLD NAFLD Lung function liver fibrosis score

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深圳市新生儿脑卒中多中心现况调查

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中国当代儿科杂志 2024年第5期26卷 450-455页

作者：时莉秀冯晋兴韦艳芳路欣茹张雨茜杨林颖何胜男陈佩娟韩静陈诚涂惠英余章斌黄进洁曾淑娟陈晚铃刘颖郭燕平毛姣玉李晓东张谦慎谢治利黄梅英晏昆山应尔雅陈俊王艳荣刘亚萍宋波刘华艳肖晓冬唐红王宇娜蔡茵莎龙琦许汉强王会战孙倩韩芳张瑞彪杨传忠窦蕾时会菊王瑞蒋萍无深圳市儿童医院新生儿科广东深圳518034 深圳市宝安区妇幼保健院新生儿科广东深圳518101 深圳市龙岗区妇幼保健院/汕头大学医学院龙岗妇幼临床学院新生儿科广东深圳518172 深圳市人民医院/暨南大学第二临床医学院/南方科技大学第一附属医院新生儿科广东深圳518020 深圳市龙岗中心医院/广州中医药大学深圳临床医学院新生儿科广东深圳518116 北京大学深圳医院新生儿科广东深圳518036 华中科技大学协和深圳医院新生儿科广东深圳518052 香港大学深圳医院新生儿科广东深圳518053 深圳市龙岗区人民医院新生儿科广东深圳518172 深圳市南山区妇幼保健院新生儿科广东深圳518067 深圳市第三人民医院新生儿科广东深圳518112 深圳市龙华区中心医院新生儿科广东深圳518110 深圳市盐田区人民医院新生儿科广东深圳518081 深圳远东妇产医院新生儿科广东深圳518002 深圳市第二人民医院新生儿科广东深圳518025 陆丰市人民医院新生儿科广东陆丰516500 惠阳三和医院新生儿科广东惠州518200 惠州市第三人民医院新生儿科广东惠州516100 深圳市妇幼保健院新生儿科广东深圳518028 南方科技大学医院新生儿科广东深圳518055 深圳市罗湖区人民医院新生儿科广东深圳518005 深圳新生儿数据协作网

目的总结深圳市新生儿脑卒中发病率、临床特征及预后等情况,提高脑卒中新生儿的早期诊治能力。方法由深圳市儿童医院牵头,收集2020年1月—2022年12月深圳新生儿数据协作网组织21家单位收治的新生儿脑卒中36例,分析深圳市新生儿脑卒中发... 详细信息

目的总结深圳市新生儿脑卒中发病率、临床特征及预后等情况,提高脑卒中新生儿的早期诊治能力。方法由深圳市儿童医院牵头,收集2020年1月—2022年12月深圳新生儿数据协作网组织21家单位收治的新生儿脑卒中36例,分析深圳市新生儿脑卒中发病率、临床特征、治疗、预后等情况。结果深圳市21家医院2020、2021、2022年新生儿脑卒中的发病率分别为1/15137、1/6060、1/7704。缺血性脑卒中占75%(27/36),男性患儿占64%(23/36)。86%(31/36)的患儿在生后3d内起病,53%(19/36)以惊厥起病。颅脑影像学结果显示,22例(61%)大脑左侧发生梗死,13例(36%)基底节梗死;12例完成磁共振血管成像检查,9例(75%)累及大脑中动脉。29例患儿完成脑电图检查,21例(72%)出现尖波,10例(34%)出现电发作。不同医院对症支持治疗不同。12例(33%)完善新生儿行为神经测定评分,平均得分(32±4)分。共随访27例患儿12月龄左右的预后情况,44%(12/27)的患儿预后良好。结论新生儿脑卒中主要为缺血性脑卒中,多以惊厥为首发症状,多累及大脑中动脉,脑电图多出现尖波,神经发育评分较低,以对症支持治疗为主,部分患儿预后不良。

关键词：脑卒中多中心研究新生儿

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Photometric Properties and Stellar Parameters of the Rapidly Rotating Magnetic Early-B Star HD 345439

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Research in Astronomy and Astrophysics 2023年第1期23卷 18-31页

作者： Dong-xiang Shen Jin-Zhong liu Chun-hua zhu Guo-liang Lü yu zhang cheng-Long Lü Hao-Zhi Wang Lei li xi-zhen Lu Jin-Long yu Abdurepqet Rustem School of Physical Science and Technology Xinjiang UniversityUrumqi 830046China xinjiang Astronomical Observatory National Astronomical ObservatoriesChinese Academy of SciencesUrumqi 830000China

We first present the multicolor photometry results of the rapidly rotating magnetic star HD 345439 using the Nanshan One-meter Wide-field *** the photometric observations,we derive a rotational period of 0.7699±0.0014 *** light curves of HD 345439 are dominated by the double asymmetric S-wave feature that arises from the magnetic *** behaviors are not observed in Sector 41 of the Transiting Exoplanet Survey *** evidence is found of the occurrence of centrifugal breakout events neither in the residual flux nor in the systematic variations at the extremum of the light *** on the hypothesis of the Rigidly Rotating Magnetosphere model,we restrict the magnetic obliquity angleβand the rotational inclination angle i so that they satisfy the approximate relationβ+i≈105°.The color excess,extinction,and luminosity are determined to be E_((B-V))=0.745±0.016 mag,A_(V)=2.31±0.05 mag,and log(L/L_(⊙))=3.82±0.1 dex,***,we derive the effective temperature as T_(eff)=22±1 kK and the surface gravity as log g=4.00±*** mass M=-7.24_(-1.24)^(+1.75)M_(⊙),radius R=4.44_(-1.93)^(+2.68)R_(⊙),and age τ_(age)=23.62_(-21.97)^(+4.24) Myr are estimated from the Hertzsprung-Russell diagram.

关键词： stars chemically peculiar-stars early-type-stars fundamental parameters-stars magnetic field

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Transcriptome-wide association analysis identified candidate susceptibility genes for nasopharyngeal carcinoma

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Cancer Communications 2022年第9期42卷 887-891页

作者： Yong-Qiao He wen-Qiong Xue Dan-hua li Tong-Min Wang Zhi-Ming Mai Da-Wei Yang Chang-Mi Deng Ying liao wen-li zhang Ruo-wen xiao Luting Luo hua Diao xiating Tong Yanxia Wu Jiang-Bo zhang Ting Zhou xi-Zhao li Pei-Fen zhang xiao-Hui zheng Shao-Dan zhang Ye-zhu Hu Minzhong Tang yuming zheng Yonglin Cai Ellen T.Chang Zhe zhang Guangwu huang Su-mei Cao Qing liu lin feng Ying Sun Maria li Lung Hans-Olov Adami Weimin Ye Tai-Hing Lam Wei-hua Jia State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer MedicineGuangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and TherapySun Yat-sen University Cancer CenterGuangzhouGuangdong 510060P.R.China School of Public Health Sun Yat-sen UniversityGuangzhouGuangdong 510080P.R.China School of Public Health The University of Hong KongHong Kong S.A.R.999077P.R.China Center for Nasopharyngeal Carcinoma Research Research Grants Council Area of Excellence SchemeThe University of Hong KongHong Kong S.A.R.999077P.R.China Radiation Epidemiology Branch Division of Cancer Epidemiology and GeneticsNational Cancer InstituteNational Institutes of HealthBethesdaMD 20892USA Wuzhou Red Cross Hospital WuzhouGuangxi 543002P.R.China Wuzhou Cancer Center WuzhouGuangxi 543002P.R.China Center for Health Sciences ExponentInc.Menlo ParkCA94025Department of Epidemiology and BiostatisticsUniversity of CaliforniaSan FranciscoCA 94143USA Department of Otolaryngology-Head and Neck Surgery First Affiliated Hospital of Guangxi Medical UniversityNanningGuangxi 530021P.R.China Department of Radiation Oncology Sun Yat-sen University Cancer CenterState Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer MedicineGuangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and TherapyGuangzhouGuangdong 510060P.R.China Department of Clinical Oncology The University of Hong KongHong Kong S.A.R.999077P.R.China Clinical Effectiveness Group Institute of Health and SocietyUniversity of OsloOslo 0316Norway Department of Medical Epidemiology and Biostatistics Karolinska InstitutetStockholm 17177Sweden Department of Epidemiology and Health Statistics&Key Laboratory of Ministry of Education for Gastrointestinal Cancer Fujian Medical UniversityFuzhouFujian 350122P.R.China

Dear Editor,Nasopharyngeal carcinoma(NPC)is a common malignancy in East and Southeast Asia,especially in South *** etiology of NPC has been linked to genetic susceptibility,Epstein-Barr virus(EBV)infection,and environmental *** evidence including multiple genome-wide association studies(GWASs)has revealed robust genetic predisposition of ***,GWAS-identified genetic variants collectively account for only 8.2%of NPC heritability[1].The underlying inherited predisposition is largely *** strongest genetic signal for NPC consistently hits the human leukocyte antigen(HLA)region on 6p21[2].However,the highly polymorphic nature and complicated long-range linkage disequilibrium(LD)in the HLA region particularly obscure the causal variants driving the *** addition,most genetic variants located in introns or intergenic *** causal genes mediating genetic effects on NPC risk have rarely been ascertained by GWAS alone.

关键词： nasopharyngeal susceptibility collective

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Paired quasi-periodic pulsations of hard X-ray emission in a solar flare

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Science China(Physics,Mechanics & Astronomy) 2023年第5期66卷 195-206页

作者： Hai-Sheng Zhao Dong li Shao-lin xiong Yan-Qiu zhang Yang Su Wei Chen Yi Zhao xiao-Bo li Jia-Cong liu wen-xi Peng Rui Qiao xin-Qiao li xiang-Yang wen li-Ming Song Shi-Jie zheng xin-Ying Song xiao-yun Zhao yue huang Shuang-Nan zhang Shuo xiao Ce Cai zheng-hua An Can Chen Gang Chen Wei Chen Yan-Qi Du Min Gao Ke Gong Dong-Ya Guo Zhi-Wei Guo Jian-Jian He Bin li Chao li Chao-Yang li Gang li Jian-Hui li Lu li Qing-xin li Yan-Guo li Jing liang xiao-hua liang Jin-yuan liao xiao-Jing liu Ya-Qing liu Qi Luo xiang Ma Bin Meng Ge Ou Dong-li Shi Jing-Yan Shi Gong-xing Sun xi-Lei Sun You-li Tuo Chen-Wei Wang Hui Wang Jin Wang Jin-Zhou Wang Ping Wang wen-Shuai Wang Hong Wu Sheng-Lun xie Yan-Bing Xu yu-Peng Xu Wang-Chen Xue Sheng Yang Min Yao Jian-Ying Ye Qi-Bin Yi Chao-yue zhang Da-li zhang Fan zhang Fei zhang Hong-mei zhang Kai zhang Peng zhang xiao-Lu zhang zhen zhang Guo-Ying Zhao Shi-Yi Zhao Chao zheng xing Zhou yue zhu Key Laboratory for Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China Purple Mountain Observatory Chinese Academy of SciencesNanjing 210023China University of Chinese Academy of Sciences Beijing 100049China Department of Astronomy Beijing Normal UniversityBeijing 100875China School of Computing and Artificial Intelligence Southwest Jiaotong UniversityChengdu 611756China Physics and Space Science College China West Normal UniversityNanchong 637002China Key Laboratory of Stellar and Interstellar Physics and Department of Physics Xiangtan UniversityXiangtan 411105China Institute of Astrophysics Central China Normal UniversityWuhan 430079China School of Physics Changchun University of Science and TechnologyChangchun 130022China College of Physics and Engineering Qufu Normal UniversityQufu 273165China College of Physics Sciences&Technology Hebei UniversityBaoding 071002China

We investigate high time resolution data obtained by the Gravitational wave high-energy Electromagnetic Counterpart All-sky Monitor(GECAM)during the flare event on 2022 April 21 at 01:52 *** subpeaks with durations of 4-6 s have been detected in the hard X-ray precursor phase,and the key feature is that they appear in pairs and seem like double-peak *** subpeaks are rarely observed in hard X-ray band and confirmed by the microwave obtained by Nobeyama Radio Polarimeters(NoRP)and Radio Solar Telescope Network(RSTN).While an exponential function can describe the continuum component of the time profile from the precursor to part of the impulsive *** periods of quasi-periodic pulsations(QPPs)are detected to be about 7.3 and 12.8 s for the precursor and impulsive phase,respectively,with at least 95%confidence *** paired QPPs are assumed to be double-peak QPPs and then the scenario of current loop coalescence model is found to be in good agreement with our *** precursor phase can be interpreted as the oscillating coalescence of two islands,while the impulsive phase can be interpreted as more islands to coalesce one by one to form larger islands.

关键词： solar flare QPPs loop coalescence circular-ribbon flare

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固支加筋方板在均布冲击载荷作用下动态响应的相似畸变研究

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哈尔滨工程大学学报 2008年第3期29卷 226-231页

作者：张振华秦健王乘李振环朱锡华中科技大学土木工程与力学学院湖北武汉430074 北京理工大学宇航科学与技术学院海军工程大学船舶与海洋工程系湖北武汉430033

通过量纲分析提出了不考虑应变率效应时固支加筋方板在均布冲击作用下动态响应的准确模型化试验方法.在此基础上,计及材料应变率强化效应,研究了固支加筋方板在均布冲击载荷作用下动态响应的相似畸变问题.通过在模型和原型之间建立一个... 详细信息

通过量纲分析提出了不考虑应变率效应时固支加筋方板在均布冲击作用下动态响应的准确模型化试验方法.在此基础上,计及材料应变率强化效应,研究了固支加筋方板在均布冲击载荷作用下动态响应的相似畸变问题.通过在模型和原型之间建立一个修正模型,使修正模型和原型的最终变形相似,从而达到利用小模型试验预报大型结构冲击响应的目的.结论对指导加筋板横向冲击的模化试验具有借鉴价值.

关键词：加筋方板冲击相似律应变率效应

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Effect of Allocryptopine on Late sodium current of atrial myocytes in spontaneously hypertensive rats

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Journal of Geriatric Cardiology 2017年第4期14卷 280-286页

作者： Ying ZHAO xiao-Ting xiE Yan-mei SUN Zhong-Qi CAI Ying DONG Chao zhu xi CHEN Hong-lin WU Jian-cheng zhang Yang li Department of Cardiology Chinese PLA General Hospital Beijing China Provincial Clinical Medicine College of Fujian Medical University Fuzhou Fujian China Cardiovascular Department Chifeng Songshan hospital of the Mongolia lnner Autonomous Region Chifeng China

Objective To explore the effect of allocryptopine （All） on the Late sodium current （INa,Late） of atrial myocytes in spontaneously hyper- tensive rats （SHR）. Method The enzyme digestion method was used to separate single atrial myocytes from SHR and Wistar-Kyoto rat （WKY） rats. INa,Late was record by patch-clamp technique and the effect of All on the current was evaluated. Results Comparing with WKY cells, markedly increasing of INa,Late current in SHR myocytes was found from 0.24 ± 0.02 pA/pF of WKY cells to 1.73± 0.04 pA/pF of SHR cells （P 〈 0.01, n = 15）. After treament with 30 μmol/L All; the current densities was reduced to 0.92 ± 0.03 pA/pF. The ratio of INa,Late/INa,peak of WKY and SHR were 0.09% ± 0.01% and 0.71% ± 0.02%, INa, Late/INa,peak of SHR was reduced to 0.37% ± 0.02% by 30 μmol/L All （P 〈 0.01, n = 15）. We also determined the effect of All on the gating mechanism of the INa,Late in the SHR cells. It was found that All decreased the INa,Late by alleviating the inactivation of the channels and increasing the window current of sodium channel. Conclusion Increased INa,Late in SHR atrial myocytes and the prolonged APD were inhibited by All coming from Chinese herb medicine.

关键词： Action potential Allocryptopine Atrial myocytes Late sodium current Spontaneously hypertensive rats

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