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Which neurological abnormalities and neuropsychological impairments share the same substrate in psychosis?

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chinese Science Bulletin 2011年第32期56卷 3372-3375页

作者： DAZZAN Paola chan Raymond c K Department of Psychosis Studies Institute of Psychiatry King's College London UK Neuropsychology and Applied cognitive Neuroscience Laboratory Key Laboratory of Mental Health Institute of Psychology Chinese Academy of Sciences Beijing 100101 China

Approximately 60% of subjects with schizophrenia present minor neurological signs (neurological soft signs, NSS), which include abnormalities in sensory and motor performance indicative of a non-specific cerebral dysfunction. These are also present in healthy individuals and relatives of patients with psychosis, at significantly lower rates. The excess of NSS in psychosis may be a potential endophenotype for this disorder, and reflect the same neurodevelopmental brain dysfunction that also underlies the cognitive deficits consistently reported in psychosis. To establish whether neurological and cognitive dysfunction meet the essential criterion required for a refined endophenotype for psychosis, the association with the illness, we explored evidence that certain neurological and cognitive deficits co-occur in affected individuals. This evidence suggests that signs of motor dysfunctions may be specific to patients with psychosis, in whom they are associated with dysfunction in cognitive tasks requiring motor skills. Thus, they may form a promising candidate endophenotype for psychosis.

关键词：精神病患者神经系统心理障碍异常脑功能障碍基板共享运动性能

Nitric oxide removal by wastewater bacteria in a biotrickling filter

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Journal of Environmental Sciences 2014年第3期26卷 555-565页

作者： Hejingying Niu Dennis Y c Leung chifat Wong Tong Zhang Mayngor chan Fred c c Leung Department of Mechanical Engineering The University of Hong Kong School of Biological Sciences The University of Hong Kong Department of civil Engineering The University of Hong Kong

Nitric oxide （NO） is one of the most important air pollutants in atmosphere mainly emitted from combustion source. A biotriclding filter was designed and operated to remove NO from an air stream using bacteria extracted from the sewage sludge of a municipal sewage treatment plant. To obtain the best operation conditions for the biotrickling filter, orthogonal experiments （L9（34）） were designed. Inlet oxygen concentration was found to be the most significant factor of the biotrickling filter and has a significant negative effect on the system. The optimal conditions of the biotrickling filter occurred at a temperature of 40℃, a pH of 8.0 and a chemical oxygen demand of 165 mg/L in the recycled water with no oxygen in the system. The bacteria sample was detected by DNA sequencing technology and showed 93%-98% similarity to Pseudomonas mendocina. Moreover, a full gene sequencing results indicated the bacterium was a brand new strain and named as P. mendocina DLHK. This strain can transfer nitrate to organic nitrogen. The result suggested the assimilation nitrogen process in this system. Through the isotope experimental analysis, two intermediate products （^15NO and ^15N2O） were found. The results indicated the denitrification function and capability of the biotrickling filter in removing NO.

关键词： NO reduction biotrickling filter orthogonal experiment Pseudomonas mendocina isotope labeling

Machine learning empowers efficient design of ternary organic solar cells with PM6 donor

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Journal of Energy chemistry 2025年第1期100卷 337-347页

作者： Kiran A.Nirmal Tukaram D.Dongale Santosh S.Sutar Atul c.Khot Tae Geun Kim School of Electrical Engineering Korea University computational Electronics and Nanoscience Research Laboratory School of Nanoscience and Biotechnology Shivaji University Yashwantrao chavan School of Rural Development Shivaji University

Organic solar cells(OScs) hold great potential as a photovoltaic technology for practical ***, the traditional experimental trial-and-error method for designing and engineering OScs can be complex, expensive, and time-consuming. Machine learning(ML) techniques enable the proficient extraction of information from datasets, allowing the development of realistic models that are capable of predicting the efficacy of materials with commendable accuracy. The PM6 donor has great potential for high-performance OScs. However, it is crucial for the rational design of a ternary blend to accurately forecast the power conversion efficiency(PcE) of ternary OScs(TOScs) based on a PM6 ***, we collected the device parameters of PM6-based TOScs and evaluated the feature importance of their molecule descriptors to develop predictive models. In this study, we used five different ML algorithms for analysis and prediction. For the analysis, the classification and regression tree provided different rules, heuristics, and patterns from the heterogeneous dataset. The random forest algorithm outperforms other prediction ML algorithms in predicting the output performance of PM6-based TOScs. Finally, we validated the ML outcomes by fabricating PM6-based TOScs. Our study presents a rapid strategy for assessing a high PcE while elucidating the substantial influence of diverse descriptors.

关键词： Random forests

cutting characteristics of Zr-Based Bulk Metallic Glass

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Journal of Materials Science & Technology 2015年第2期31卷 153-158页

作者： D.x.Han G.Wang J.Li K.c.chan S.To F.F.Wu Y.L.Gao Q.J.Zhai Laboratory for Microstructures Shanghai University Department of Industrial and System Engineering The Hong Kong Polytechnic University

cutting behavior exerts a considerable influence on the fabrication of bulk metallic glass(BMG) components. In this study,the influences of machining parameters(i.e.,depth of cutting,feed rate,and spindle rate) on the turned surface of a Zr-based BMG after observing the 3D morphologies of this surface were *** results showed that the influence of the spindle rate on the surface morphologies is more substantial as compared to the depth of cutting and the feed rate. Nanoscratch tests were conducted to further characterize the separation mechanism of the chips,which revealed that the chips are torn off the surface of a BMG because of inhomogeneous localized maximum shear stress.

关键词： Bulk metallic glass Ultra-precision machining Surf

Mechanical Properties and Defective Effects of 316LN Stainless Steel by First-Principles Simulations

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Journal of Materials Science & Technology 2011年第11期27卷 1029-1033页

作者： x.Q. Li J.J. Zhao J.c. xu x. Liu Key Laboratory of Materials Modification by Laser Ion and Electron Beams Ministry of Education Dalian University of Technology Dalian 116024 China college of Advanced Science and Technology Dalian University of Technology Dalian 116024 China School of chemical Engineering Dalian University of Technology Dalian 116024 China

In current International Thermonuclear Experimental Reactor （ITER） design, the 316LN austenitic stainless steel （316LN SS） is used for first-wall/blanket structures. Thus, it is necessary to study the fundamental mechanical properties and irradiation effect of 316LN SS. A random solid solution model of Fe-cr-Ni-Mn- Mo-Si alloy is used for describing 310LN S$. Using first-principles approaches, the elastic constants and ideal strength of the alloy were calculated. Such alloy exhibits good ductile behavior according to the theoretical values of cauchy pressure and ratio of bulk modulus and shear modulus. Within the 256-atom supercell, inclusion of single vacancy defect further enhances the ductility of the alloy, and the existence of interstitial （Fe, H, He） atoms enhances the Young＇s modulus.

关键词： Stainless steel Mechanical properties Vacancy Interstitial

Electrically conductive Honeycomb Monolith of Nanolaminated Ti_3Alc_2:Preparation and characterization

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Journal of Materials Science & Technology 2015年第1期31卷 125-128页

作者： x.M.Fang x.H.Wang H.Zhang Y.c.Zhou Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of Sciences University of chinese Academy of Sciences Science and Technology of Advanced Functional composite Laboratory ARIMPT

Nanolaminated Ti3Alc2honeycomb monolith with parallel and uniform holes has been prepared through a facile extrusion route by using Ti3Alc2powder as the main raw *** fabricated honeycomb monolith has high compressive strength of 133 ± 11 and 59 ± 9 MPa,along and perpendicular to the extrusion direction,*** also has good electrical conductivity,and excellent match of thermal expansion coefficient with the washcoat material of γ-*** combined properties endow the honeycomb monolith a promising candidate as catalysis substrate for cleaning vehicle exhaust.

关键词： Honeycomb ceramic Ti3Alc2 Extrusion catalysis

High-magnetic-field induced charge order in high-T_c cuprate superconductors

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chinese Physics B 2019年第11期28卷 25-42页

作者： L x Zheng J Li T WU Hefei National Laboratory for Physical Science at Microscale University of Science and Technology of ChinaHefei 230026China Key Laboratory of Strongly-coupled Quantum Matter Physics University of Science and Technology of ChinaChinese Academy of SciencesHefei 230026China cAS center for Excellence in Superconducting Electronics(cENSE) Shanghai 200050China cAS center for Excellence in Quantum Information and Quantum Physics Hefei 230026China collaborative Innovation center of Advanced Microstructures Nanjing UniversityNanjing 210093China

In the last few years, charge order and its entanglement with superconductivity are under hot debate in high-Tc community due to the new progress on charge order in high-Tc cuprate superconductors YBa2cu3O6+x. Here, we will briefly introduce the experimental status of this field and mainly focus on the experimental progress of high-field nuclear magnetic resonance(NMR) study on charge order in YBa2cu3O6+x. The pioneering high-field NMR work in YBa2cu3O6+x sets a new stage for studying charge order which has become a ubiquitous phenomenon in high-Tc cuprate superconductors.

关键词： charge order cuprates nuclear magnetic resonance YBa2cu3O6+x superconductors competing order

Recent experimental progress of fractional quantum Hall effect: 5/2 illing state and graphene

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National Science Review 2014年第4期1卷 564-579页

作者： x.Lin R.R.Du x.c.xie International center for Quantum Materials Peking University

The phenomenon of fractional quantum Hall efect(FQHE)was irst experimentally observed 33 years *** involves strong coulomb interactions and correlations among the electrons,which leads to quasiparticles with fractional elementary *** decades later,the ield of FQHE is still active with new discoveries and new technical developments.A signiicant portion of atention in FQHE has been dedicated to illing factor 5/2 state,for its unusual even denominator and possible application in topological quantum ***,FQHE has been observed in high-mobility Ga As heterostructure,but new materials such as graphene also open up a new area for *** review focuses on recent progress of FQHE at 5/2 state and FQHE in graphene.

关键词： fractional quantum Hall efect experimental progress 5/2 state graphene

Sensitivity of precipitation statistics to urban growth in a subtropical coastal megacity cluster

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Journal of Environmental Sciences 2017年第9期29卷 6-12页

作者： christopher claus Holst Johnny c.L.chan chi-Yung Tam School of Energy and Enuironment City Uniuersity of liong KongHong KongChina Guy carpenter Asia-Pacific climate Impact centre City Uniuersity of Hong KongHong KongChina Earth System Science Programme The Chinese Uniuersity of Hong KongHong KongChina

This short paper presents an investigation on how human activities may or may not affect precipitation based on numerical simulations of precipitation in a benchmark case with modified lower boundary conditions, representing different stages of urban development in the model. The results indicate that certain degrees of urbanization affect the likelihood of heavy precipitation significantly, while less urbanized or smaller cities are much less prone to these effects. Such a result can be explained based on our previous work where the sensitivity of precipitation statistics to surface anthropogenic heat sources lies in the generation of buoyancy and turbulence in the planetary boundary layer and dissipation through triggering of convection. Thus only mega cities of sufficient size, and hence human-activity-related anthropogenic heat emission, can expect to experience such effects. In other words, as cities grow, their effects upon precipitation appear to grow as well.

关键词： Urban precipitation Micro climate sensitivity Urbanization