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Tailoring grain growth and solid solution strengthening of single-phase CrCoNi medium-entropy alloys by solute selection

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Journal of Materials Science & Technology 2020年第19期54卷 196-205页

作者： G.w.Hu L.C.Zeng H.Du x.w.liu Y.wu P.Gong Z.T.Fan Q.Hu E.P.George Key Laboratory of Metallurgical Equipment and Control Technology Ministry of EducationWuhan University of Science and TechnologyWuhan 430081China Hubei Key Laboratory of Mechanical Transmission and Manufacturing Engineering Wuhan University of Science and TechnologyWuhan 430081China State Key Laboratory of Materials Processing and Die&Mould Technology Huazhong University of Science and TechnologyWuhan 430074China State Key Laboratory for Advanced Metals and Materials University of Science and Technology BeijingBeijing 100083China Institute of Applied Physics Jiangxi Academy of SciencesNanchang 330029China Oak Ridge National Laboratory Materials Science and Technology DivisionOak RidgeTN37831USA Department of Materials Science and Engineering University of TennesseeKnoxvilleTN37996USA

In the present study,we selected solutes to be added to the Cr Co Ni medium-entropy alloy(MEA)based on the mismatch of self-diffusion activation energy(SDQ)between the alloying elements and constituent elements of the matrix,and then investigated their grain growth behavior and mechanical *** and Al were selected as the solutes for investigation primarily because they have higher and lower SDQ,respectively,than those of the matrix elements;a secondary factor was their higher and lower shear *** concentrations were fixed at 3 at.%each because previous work had shown these compositions to be single-phase solid solutions with the face-centered cubic *** alloys were produced by arc melting,casting,homogenizing,cold rolling and annealing at various temperatures and times to produce samples with different grain *** were(a)the base alloy Cr Co Ni,(b)the base alloy plus 3 at.%Mo,and(c)the base alloy plus 3 at.%*** activation energies for grain growth of the Cr Co Ni,Cr Co Ni-3Mo and CrCo Ni-3Al MEAs were found to be^251,~368 and^219 k J/mol,respectively,consistent with the notion that elements with higher SDQ(in this study Mo)retard grain growth(likely by a solute-drag effect),whereas those with lower values(Al)accelerate grain *** roomtemperature tensile properties show that Mo increases the yield strength by^40%but Al addition has a smaller strengthening effect consistent with their relative shear *** yield strength as a function of grain size for the three single-phase MEAs follows the classical Hall-Petch relationship with much higher slopes(>600 MPaμm-0.5)than traditional solid *** work shows that the grain growth kinetics and solid solution strengthening of the Cr Co Ni MEA can be tuned by selecting solute elements that have appropriate diffusion and physical properties.

关键词： Medium and high entropy alloys Solute-drag effect Microstructure Grain growth kinetics Solid solution strengthening

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Improving high-temperature mechanical properties of cast CrFeCoNi high-entropy alloy by highly thermostable in-situ precipitated carbides

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Journal of Materials Science & Technology 2021年第13期72卷 29-38页

作者： x.w.liu N.Gao J.Zheng Y.wu Y.Y.Zhao Q.Chen w.Zhou S.Z.Pu w.M.Jiang Z.T.Fan State Key Laboratory of Materials Processing and Die&Mould Technology School of Materials Science and EngineeringHuazhong University of Science and TechnologyWuhan430074China Institute of Nuclear Physics and Chemistry China Academy of Engineering PhysicsMianyang 621999China State Key Laboratory for Advanced Metals and Materials University of Science and Technology BeijingBeijing 100083China School of Materials Engineering Purdue UniversityWest LafayetteIN 47907USA Southwest Technology and Engineering Research Institute Chongqing 400039China Center for Electron Microscopy Wuhan UniversityWuhan 430072China

The Cr Fe Co Ni high-entropy alloy(HEA)exhibits excellent mechanical properties at lower temperatures due to its low stacking-fault energy,however,its medium-and high-temperature strengths are still *** consideration of the potential diversified applications,more strengthening approaches except for the previously proposed L12 phase hardening deserve further exploration due to its rapid coarsening tendency at high ***,we achieved significant high-temperature strengthening of the cast Cr Fe Co Ni HEA by in-situ precipitation of highly thermostable *** with 0.5 at.%and 1 at.%niobium and carbon were prepared by simple casting processes,*** cast,solute solution and aging.A highly thermostable microstructure was formed,which comprises very coarse grains accompanied with extensive thermostable carbide precipitates embedded,including submicrometer coherent Nb C particles in grain interiors and intergranular coherent M_(23)C_(6)*** high thermostability of microstructure,which is beneficial for the high-temperature loading,is ascribed to the synergy of lacking growth driving force and Zenner pinning effect by the *** properties tested at 673,873 and1073 K show that the yield strength and ultimate tensile strength are significantly increased by Nb/C doping,along with the elongation escalation at higher *** strengthening is mainly due to the precipitation hardening of carbide particles.

关键词： High-entropy alloy Carbides Precipitation High-temperature property Strengthening

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Osteogenesis and angiogenesis of a bulk metallic glass for biomedical implants

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Bioactive Materials 2022年第2期7卷 253-266页

作者： K.Sun R.Fu x.w.liu L.M.xu G.wang S.Y.Chen Q.J.Zhai S.Pauly Institute of Materials Shanghai UniversityShanghai200444China Department of Neurology Tongren HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai200336China Sports Medicine Department of Huashan Hospital Fudan UniversityShanghai200040China University of Applied Sciences Aschaffenburg Würzburger Straße 45D-63743AschaffenburgGermany

Implantation is an essential issue in orthopedic *** metallic glasses(BMGs),as a kind of novel materials,attract lots of attentions in biological field owing to their comprehensive excellent ***,we show that a Zr_(61)Ti_(2)Cu_(25)Al_(12)(at.%)BMG(Zr-based BMG)displays the best cytocompatibility,pronounced positive effects on cellular migration,and tube formation from in-vitro tests as compared to those of commercial-pure titanium and *** in-vivo micro-CT and histological evaluation demonstrate the Zr-based BMG can significantly promote a bone *** tests and digital reconstructed radiographs manifest a stimulated effect on early blood vessel formation from the Zr-based ***,the intimate connection and coupling effect between angiogenesis and osteogenesis must be effective during bone regeneration after implanting Zr-based *** gait analysis in rats after implanting Zr-based BMG demonstrates a tendency to decrease the pain level during recovery,simultaneously,without abnormal ionic accumulation and inflammatory *** suitable mechanical properties,we provide a realistic candidate of the Zr61Ti2Cu25Al12 BMG for biomedical applications.

关键词： Metallic glasses Bio-corrosion Biocompatibility Osteogenesis Angiogenesis

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椎体血管成形术用于治疗不伴有神经功能障碍的症状性椎体血管瘤

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国际医学放射学杂志 2013年第6期 599-600页

作者： x.w.liu P.Jin L.J.wang M.Li G.Sun 程悦 Department of Medical Imaging Jinan Military General Hospital

摘要目的评价椎体血管成形术在不伴有神经功能障碍的症状性椎体血管瘤(VH)中的疗效,影像学上伴或不伴有侵袭性特征。方法回顾性分析31例因症状性VH接受椎

关键词：椎体血管成形术症状性椎体血管瘤诊断

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骨水泥成型术治疗脊柱外转移性骨痛

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国际医学放射学杂志 2014年第3期 298-298页

作者： G.Sun P.Jin x.w.liu M.Li L.Li 唐光健 Department of Medical Imaging Jinan Military General Hospital

摘要目的阐明脊柱外疼痛性骨转移病人骨水泥治疗的作用。方法 51例接受CT或透视引导下骨水泥成型术的病人被纳入研究,共65处病变,病变部位包括髂骨、坐骨、耻

关键词：骨水泥丙烯酸脂粘固剂成型术脊柱

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比较经皮长骨骨水泥成形术是否嵌入骨水泥注入导管对有将要骨折的骨转移疼痛的缓解

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国际医学放射学杂志 2017年第2期 229-229页

作者： x.w.liu P.Jin K.liu H.Chen L.Li M.LI 王凤丹 Department of Orthopedics Beijing Friendship HospitalCapital Medical University

摘要目的比较经皮长骨骨水泥成形术(PLBC)是否嵌入骨水泥注入导管(ECFC)对有将要骨折的骨转移疼痛的缓解有效性。方法回顾性分析36例病人,包括接受PLBC联

关键词：骨水泥丙烯酸脂粘固剂长骨成形术导管木质部疼痛骨转移

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Interplay between creeping fat and gut microbiota: A brand-new perspective on fecal microbiota transplantation in Crohn's disease

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world Journal of Gastroenterology 2025年第2期31卷 138-143页

作者： Ying wang Jie liu Department of Life Sciences and Medicine South District of Endoscopic CenterThe First Affiliated Hospital of University of Science and Technology of ChinaUniversity of Science and Technology of ChinaHefei 230001Anhui ProvinceChina Department of Gastroenterology The First Affiliated Hospital of University of Science and Technology of ChinaHefei 230001Anhui ProvinceChina

Inflammatory bowel disease,particularly Crohn's disease(CD),has been linked to modifications in mesenteric adipose tissue(MAT)and the phenomenon known as"creeping fat"(CrF).The presence of CrF is believed to serve as a predictor for early clinical recurrence following surgical intervention in patients with ***,the incorporation of the mesentery during ileocolic resection for CD has been correlated with a decrease in surgical recurrence,indicating the significant role of MAT in the pathogenesis of *** numerous studies have indicated that dysbiosis of the gut microbiota is a critical factor in the development of CD,the functional implications of translocated microbiota within the MAT of CD patients remain *** manuscript commentary discusses a recent basic research conducted by wu et *** their study,intestinal bacteria from individuals were transplanted into CD model mice,revealing that fecal microbiota trans-plantation(FMT)from healthy donors alleviated CD symptoms,whereas FMT from CD patients exacerbated these ***,FMT was found to affect intestinal permeability,barrier function,and the levels of proinflammatory factors and ***,these findings suggest that targeting MAT and CrF may hold therapeutic potential for patients with ***,the study did not evaluate the composition of the intestinal microbiota of the donors or the subsequent alterations in the gut ***,the gut microbiota plays a crucial role in the histopathology of CD,and thus,targeting MAT and CrF may represent a promising avenue for treatment in this patient population.

关键词： Crohn's disease Mesenteric adipose tissue Creeping fat Fecal microbiota transplantation Gut microbiota

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Recent developments of surface complexation models applied to environmental aquatic chemistry

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Journal of Environmental Sciences 2001年第4期13卷 422-434页

作者： liu, w.-x. Tang, H.-x. SKLEAC Res. Cntr. Eco-Environmental Sci. Chinese Academy of Sciences Beijing 100085 China

Based on numerous latest references, the current developments in surface complexation, surface precipitation and the corresponding models (SCMs and SPMs), were reviewed. The contents involved comparison on surface charge composition and layer-structure of solid-solution interface for the classical 1-pK and 2-pK models. In addition, the fundamental concept and relations of the new models, i. e., multi-site complexation (MUSIC) and charge- distribution (CD) MUSIC models were described as well. To avoid misuse or abuse, it must be emphasized that the applicability and limitation for each model should be considered carefully when selecting the concerned model(s). In addition, some new powerful techniques for surface characterization and analysis applied to model establishment and modification were also briefly introduced.

关键词： Complexation Precipitation (chemical)

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Network pharmacology:Changes the treatment mode of"one disease-one target"in cancer treatment

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world Journal of Gastrointestinal Oncology 2025年第1期17卷 268-271页

作者： Shuai liu Yong-wei Yu Department of Cardiology The First People’s Hospital of JiashanJiaxing 314100Zhejiang ProvinceChina Department of Critical Care Medicine The First Affiliated Hospital of Zhejiang University School of MedicineHangzhou 310000Zhejiang ProvinceChina

The article concluded that network pharmacology provides new ideas and insights into the molecular mechanism of traditional Chinese medicine(TCM)treatment of *** is a new choice and hot spot in the field of cancer *** have also previously published studies on TCM and network *** this letter,we summarize the new paradigm of network pharmacology in cancer treatment mechanisms.

关键词： Network pharmacology Cancer Multicomponent Multitarget Therapy

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Interconnections between diabetic corneal neuropathy and diabetic retinopathy:diagnostic and therapeutic implications

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Neural Regeneration Research 2025年第8期20卷 2169-2180页

作者： Mingyi Yu Faith Teo En Ning Chang liu Yu-Chi liu Tissue Engineering and Stem Cell Group Singapore Eye Research InstituteSingapore Yong Loo Lin School of Medicine National University of SingaporeSingapore Department of Cornea and External Eye Disease Singapore National Eye CenterSingapore Ophthalmology and Visual Sciences Academic Clinical Program Duke-NUS Medical SchoolSingapore

Diabetic corneal neuropathy and diabetic retinopathy are ocular complications occurring in the context of diabetes *** corneal neuropathy refers to the progressive damage of corneal *** retinopathy has traditionally been considered as damage to the retinal ***,growing evidence suggests that diabetic retinopathy is a complex neurovascular disorder resulting from dysfunction of the neurovascular unit,which includes both the retinal vascular structures and neural *** retinopathy is one of the leading causes of blindness and is frequently screened for as part of diabetic ocular ***,diabetic corneal neuropathy is commonly overlooked and underdiagnosed,leading to severe ocular surface *** studies have found that these two conditions tend to occur together,and they share similarities in their pathogenesis pathways,being triggered by a status of chronic *** review aims to discuss the interconnection between diabetic corneal neuropathy and diabetic retinopathy,whether diabetic corneal neuropathy precedes diabetic retinopathy,as well as the relation between the stage of diabetic retinopathy and the severity of corneal *** also endeavor to explore the relevance of a corneal screening in diabetic eyes and the possibility of using corneal nerve measurements to monitor the progression of diabetic retinopathy.

关键词： cornea corneal nerves diabetes diabetic corneal neuropathy diabetic retinopathy retina

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