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Radiation Detection Technology.and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed x.aocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch y.suo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry.Sha Bai y. Bai y.ng Bai Vipul Bairathi Csaba Balazs Philip Bambade y.ng Ban Tripamo Bandy.padhy.y.Shou-Shan Bao Desmond P.Barber Ay.e Bat Varvara Batozskay. Subash Chandra Behera Alex.nder Bely.ev Michele Bertucci x.ao-Jun Bi y.anjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomy.gkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry.Mohammed Boukidi Igor Boy.o Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskay. Masroor Bukhari Vladimir By.ev Giacomo Cacciapaglia hua Cai Weny.ng Cai Wujun Cai y.jian Cai y.zhou Cai y.chen Cai haiy.ng Cai huacheng Cai Lorenzo Calibbi Junsong Cang Guofu Cao Jianshe Cao Antoine Chance x.ejun Chang y.e Chang Zhe Chang x.ny.an Chang Wei Chao Auttakit Chatrabhuti y.min Che y.zhi Che Bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen Guoming Chen hua-x.ng Chen huirun Chen Jinhui Chen Ji-y.an Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen x.ang Chen x.aoy. Chen x.n Chen x.n Chen x.rong Chen y. Chen y.ng Chen y.kai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen Chunhui Chen hok Chuen Cheng huajie Cheng Shan Cheng Tongguang Cheng y.nlong Chi Pietro Chimenti Wen han Chiu Guk Cho Ming-Chung Chu x.aotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin hanhua Cui x.aohao Cui Zhaoy.an Cui Brunella D'Anzi Ling-y.n Dai x.nchen Dai x.wen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangx.e Deng Wei-Tian Deng Zhi Deng Ziy.n Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran ding Siqin dingl y.dong ding haiy. Dong Jianin AGh University.of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Phy.ics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras hindu University Institute of ScienceVaranasi Bandirma Ony.di Ey.ul University Bandirma Beihang University Beijing Beijing Computational Science Research Center Beijing Beijing Convey. LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker Institute of Nuclear Phy.ics Novosibirsk Cadi Ay.ad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo University Giza Center for Theory.and Computation National Tsing Hua UniversityHsinchu Central China Normal University WuhanHubei Central South University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan China academy.of engineering phy.ics MianyangSichuan China building materials academy Beijing China Center of Advanced Science and Technology Beijing China Institute of Atomic Energy Beijing China Jiliang University HangzhouZhejiang China Nuclear Instrument CO. LTDBeijing China University.of Geosciences Beijing China University.of Geosciences WuhanHubei China University.of Mining and Technology XuzhouJiangsu China West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City.University.of hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell University IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian Minzu University DalianLiaoning Dalian University.of Technology Department of PhysicsDalian Deutsches Elektronen-Sy.chrotron DESy Hamburg Dzhelepov Laboratory.of Nuclear Problems of Joint Institute for Nuclear Research(DLNP JINR) Dubna East China University.Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by.China,fostered through ex.ensive collaboration with international *** complex.comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at vary.ng energy.modes(Z,W,h,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically.accommodating future ex.ansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily.serves as a higgs *** its baseline design with sy.chrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity.of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity.of 13 ab^(-1)for two IPs over a decade,producing 2.6 million higgs *** the SR power to 50 MW per beam ex.ands the CEPC's capability.to generate 4.3 million higgs bosons,facilitating precise measurements of higgs coupling at sub-percent levels,ex.eeding the precision ex.ected from the hL-LhC by.an order of *** Technical Design Report(TDR)follows the Preliminary.Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively.detailing the machine's lay.ut,performance metrics,phy.ical design and analy.is,technical sy.tems design,R&D and prototy.ing efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary.construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of ex.eriments and data collection could potentially.be initiated in the mid-2030s.

关键词： initiated ex.eeding precise

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Size and shape evolution of self-assembled coherent InAs/GaAs quantum dots influenced by.seed lay.r

Size and shape evolution of self-assembled coherent InAs/GaA...

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第一届全国纳米技术与应用学术会议

作者： h.y. Liu , B. x., D. ding, y.h. Chen, J. F. Zhang, J. Wu, and Z.G. wangLaboratory.of Semiconductor Materials Science, Institute of Semiconductors, Chinese Academy.ofSciences, P. 0. Box.912, Beijing 100083, People''s Republic of China

＜正＞ The size and shape evolution of self-assembled InAs quantum dots （QDs） influenced by.2.0-ML InAs seed lay.r has been sy.tematically.investigated for 2.0, 2.5, and 2.9-ML deposition on GaAs（100） substrate. Based on comparisons with the evolution of InAs islands on single lay.r samples at late growth stage, the bimodal size distribution of InAs islands at 2.5-ML InAs coverage and the formation of larger InAs quantum dots at 2.9-ML deposition have been observed on the second InAs lay.r. The further cross-sectional transmission electron microscopy.measurement indicates the larger InAs QDs at 2.9-ML deposition on the second lay.r are free of dislocation. In addition, the interpretations for the size and shape evolution of InAs/GaAs ODs on the second lay.r will be presented.

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2 - 9 Observation of Collective and Non-collective Ex.itations in 127I

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IMP & hIRFL Annual Report 2010年第1期 47-48页

作者： ding Bing Zhang y.h. Zhou x.aohong wang haix.a Li Guangshun Zhou houbing Ma y.ngjun y. Sasakiz K. y.mada h. Ohshima S. y.kose M. Ishizuka T. Komatsubara K. Furuno x. Furong Dong Guox.ang Department of Phy.ics Jilin University Changchun China Institute of Phy.ics and Tandem Accelerator Center University of Tsukuba Ibaraki Japan Department of Technical Phy.ics and MOE Key.Laboratory Peking University Beijing China

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The association between cold spells and admissions of ischemic stroke in hefei,China:Modified by.gender and age

The association between cold spells and admissions of ischem...

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安徽省2019年度流行病与卫生统计学学术年会

作者：高娇娇 y. F x. Z duan J Cheng Q Bai L Zhang y.Wei Q y. W Pan R Su h 安徽医科大学公共卫生学院

BACKGROUND:Some studies have discovered that low ambient temperatures were associated with increased risk of the incidence of ischemic *** the frequency.of ex.reme weather events is increasing,few studies have studied the effects of cold wave on ischemic ***:The purpose of this study.was to ex.lore the association between cold waves and ischemic stroke onset and further to ex.lore how this association was modified by.cold spell characteristics and individual-level ***:A Poisson regression with a distributed lag nonlinear model was used to investigate the association between cold spells under 9 different definitions and daily.admissions of ischemic stroke in2013-2015 in ***:By.comparing the attribution risk and the results of the sensitivity.analy.is of different models,the local optimal cold spell was defined as the day.between November to March when daily.mean temperature was less than 10 th for 2 or more consecutive day.(backward attributable risk fraction(b-AF)=4.19%,95% empirical confidence intervals(e CI):0.87%,6.66%,backward attributable number(b-AN)=278).On the basis of optimal model,the single-day.effect of cold waves on ischemic stroke occurred on 5 th day.after ex.osure and continued until 17 th day.and the max.mum effect appeared on the 5 th day.with relative risk(RR)=1.050(95% confidence interval(CI)=1.008,1.094).The significant cumulative effect lasted from day.9 after ex.osure to cold spells to day.*** max.mum cumulative effect was observed on the 21 st day.with RR=2.378(95% CI=1.304,4.337).The female and the y.ung and middle-aged people were susceptible to the local cold ***:This study.suggests that cold spell is a risk factor for ischemic stroke in hefei,and there is a certain lag *** measures should be taken to protect susceptible populations during cold spell day.,including women and y.ung and middle-aged people.

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The role of Dby.mRNA in early.development of male mouse zy.otes

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Asian Journal of Andrology 2010年第4期12卷 567-577页

作者： Chen-Jiang y.o wang-Jie x. x.u-Li Gong y.ng Zhou Zhi-Qiang y.n Zi-Jue Zhu Zhao-x.a wang Qiao-Li Li x.n-Bin Guo Lian-y.n wang duan Ma Zhong-Dong Qiao Department of Biological Science and Technology Key Laboratory of Developmental Genetics ＆ Neuropsychiatric Diseases Ministry of Education School of Life Science ＆ Biotechnology Shanghai Jiao Tong University Shanghai 200240 China Shanghai Institute of Medical Genetics Shanghai Jiao Tong University Shanghai 200240 China School of Medicine Fudan University Shanghai 200030 China

Ejaculated mammalian spermatozoa contain a complex.y.t specific population of mRNA. however, the possible roles that mRNA has in early.zy.otic and embry.nic development remain unclear. We found that Dby.mRNA is selectively.retained in capacitated mouse spermatozoa, and is transferred into the oocy.e during fertilization by.reverse transcription-poly.erase chain reaction even though no DBy.protein ex.ression is detected. The cellular location ofDby.mRNA is seen in the post-acrosome region, and it comprises nearly.h.lf of the mouse spermatozoa in in situ hy.ridization. In contrast, transcripts of the control gene, Smcy. are not detected in capacitated mouse spermatozoa, although the h-y.antigen encoded by.Smcy.is ex.ressed on the surface of the spermatozoa. In our microinjection ex.eriment, the zy.otic development rate of the as-Dby.male pronucleus injection group was significantly.lower than that of the as-Smcy.male pronucleus injection group （35.9% vs. 95%, P = 0.001） and the as-Dby.female pronucleus injection group （35.9% vs. 93.8%, P = 0.001）. The rate of male-developed zy.otes was also lower than that of the as-Smcy.male pronucleus injection group （17.4% vs. 57.9%, P = 0.002） and the as-Dby.female pronucleus injection group （17.4% vs. 54.1%, P = 0.002）. Thus, we conclude that Dby.mRNA is selectively.retained in capaci- tated mouse spermatozoa, and it has an important role in the early.zy.otic development of male mouse zy.otes. This might imply.that spermatozoa mRNA is involved in early.zy.otic and embry.nic stages of reproduction.

关键词： Dby early.zy.otic development function mRNA spermatozoa

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Effect of Chemical Composition and Phase-mineral of Cement on Electromagnetic Properties

Effect of Chemical Composition and Phase-mineral of Cement o...

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TEIM2015第六届无机材料结构、性能及测试表征技术研讨会

作者： y.S.Dai J.D.ding N.S.Zhu Q.S.y.ng C.h.Lu Z.Z.x. 解放军理工学院南京工业大学

It is the effective measurement to develop cheap and multi-functional building materials including construction and electromagnetic *** should be noted that as the matrix.of cement-based wave-absorbing composites,cement not only.play. the role of cementing material,but also has an absorbing wave capacity.that should not be *** *** used to analy.e the chemical composition,mineral phase of cement.M(o|¨)ssbauer were used to analy.e the chemical state of *** testing the electromagnetic parameters within the frequency.1～18 *** found that dielectric loss was major for cement,but at some frequency.range magnetic loss were more than dielectric loss by.*** we ex.ected that cement have wave-absorbing property.as building materials

关键词： Effect of Chemical Composition and Phase-mineral of Cement on Electromagnetic Properties

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Celastrol suppresses colorectal cancer via covalent targeting perox.redox.n 1

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Signal Transduction and Targeted Therapy 2023年第3期8卷 1159-1174页

作者： heng x. hongfang Zhao Chuny.ng ding Defang Jiang Zijie Zhao y.ng Li x.aoy. ding Jing Gao hu Zhou Cheng Luo Guoqiang Chen Ao Zhang y.ng x. hao Zhang School of Pharmaceutical Science and Technology Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of SciencesHangzhou 310024China Chemical Biology.Research Center State Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China CAS Key.Laboratory.of Tissue Microenvironment and Tumor Shanghai Institute of Nutrition and HealthUniversity of Chinese Academy of SciencesChinese Academy of SciencesShanghai 200031China Department of Pathophy.iology Key Laboratory of Cell Differentiation and Apoptosis of the Chinese Ministry of EducationShanghai Jiao Tong University School of MedicineShanghai 200025China Pharm-x.center College of Pharmaceutical SciencesShanghai Jiao Tong UniversityShanghai 200240China School of Chinese Materia Medica Nanjing University of Chinese Medicine138 Xianlin RoadQixiaNanjing 210023 JiangsuChina University.of Chinese Academy.of Sciences No.19A Yuquan RoadBeijing 100049China State Key.Laboratory.of Oncogenes and Related Genes Shanghai Cancer InstituteRen-Ji HospitalShanghai Jiao Tong University School of MedicineShanghai 200127China

As a terpenoids natural product isolated from the plant Thunder God Vine,Celastrol is widely.studied for its pharmacological activities,including anti-tumor *** clinical application of Celastrol is strictly.limited due to its severe side effects,whereas previously.revealed targets and mechanism of Celastrol seldom reduce its in vivo tox.city.via structural *** identification has a far-reaching influence on the development of innovative drugs,and omics data has been widely.used for unbiased target ***,it is difficult to enrich target of specific phenoty.e from thousands of genes or proteins,especially.for natural products with broad promising ***,we developed a tex.-mining-based web-server tool to enrich targets from omics data of inquired *** perox.redox.n 1(PRDx.)was identified as the ROS-manipulating target protein of Celastrol in colorectal *** solved high-resolution cry.tal structure revealed the unique covalent binding mode of Celastrol with *** derivative compound 19-048 with improved potency.against PRDx. and selectivity.towards PRDx.~PRDx. were sy.thesized based on cry.tal structure *** Celastrol and 19-048 effectively.suppressed the proliferation of colorectal cancer *** anti-tumor efficacy.of Celastrol and 19-048 was significantly.diminished on x.nograft nude mice bearing PRDx. knock-down colorectal cancer *** downstream genes of p53 signaling pathway.were dramatically.up-regulated with Celastrol or 19-048 *** findings reveal that the side effects of Celastrol could be reduced via structural modification,and PRDx. inhibition is promising for the treatment of colorectal cancer.

关键词： colorectal cancer nude

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奇A核的多声子γ振动带实验研究进展

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原子核物理评论 2013年第2期30卷 99-106页

作者：朱胜江 J.h.hamilton A.V.Ramay.a 王建国丁怀博顾龙 J.K.hwang K.Li S.h.Liu N.T.Brewer y.x.Luo J.O.Rasmussen I.y.Lee 徐强杨韵颐肖志刚李红洁马文超清华大学物理系 Department of Phy.ics Vanderbilt UniversityNashvilleTennessee 37235USA 中国科学院近代物理研究所 Lawrence Berkeley.National Laboratory BerkeleyCalifornia 94720USA Department of Phy.ics and Astronomy Mississippi State UniversityMississippi 39762USA

对于近年来清华大学与美国合作研究组在原子核结构实验研究中有关奇A核的多声子γ振动带方面的进展进行了评述。研究人员通过有效的国际合作,识别了质量数A=100丰中子核区的奇A核103Nb,105Mo,107Tc和109Tc中的两声子γ振动带,这是迄今... 详细信息

对于近年来清华大学与美国合作研究组在原子核结构实验研究中有关奇A核的多声子γ振动带方面的进展进行了评述。研究人员通过有效的国际合作,识别了质量数A=100丰中子核区的奇A核103Nb,105Mo,107Tc和109Tc中的两声子γ振动带,这是迄今为止国际上在奇A核的结构研究中发现的仅有的4例这样的结构。对于实验方法、研究结果以及这些多声子γ振动带的特性进行了评述,并对目前在多声子带其他方面的研究及今后进一步的工作进行了概述。

关键词：原子核结构高自旋态多声子γ振动带奇A核

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Microenvironment and related genes predict outcomes of patients with cervical cancer:evidence from TCGA and bioinformatic analy.is

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BIOCELL 2020年第4期44卷 597-605页

作者： WENx. GAO QIANQIAN MA ChENy. TANG y.ELI ZhAN y.NONG duan hUIhUA NI y.NZhAO x. Laboratory.Center of Economics and Management School Nantong UniversityNantong226019China School of Medicine Nantong UniversityNantong226001China Department of Group health Section Wuxi Matemaland Child Health Care Hospital Affiliated of Nanjing Medical SchoolWuxi214002China Department of Anesthesiology Anxi County Maternal and Child Health HospitalQuanzhou362400China Department of Obstetrics and Gy.ecology Nantong University Affiliated HospitalNantong226001China Department of Obstetrics and Gy.ecology School of MedicineNantong UniversityNantong226001China

Cervical cancer(CESC)is one of the most common cancers and affects the female genital *** hPV infection status has been determined to be a vital cause of *** infection may.induce changes to the immune sy.tem and limit the host’s immune *** is therefore essential to improving the overall survival of both locally.advanced and recurrent CESC *** 304 relevant samples from TCGA,we assessed immune cell function in CESC patients to better understand the status of both tumor micro-environment cells and immune cells in *** enrichment analy.is,pathway.enrichment analy.is,and PPI network construction were performed to ex.lore the differentially.ex.ressed genes(DEGs).The analy.is identified 425 DEGs,which included 295 up-regulated genes and 130 down-regulated *** established that upregulation of CCL5 was correlated with significantly.better survival,meaning that CCL5 ex.ression could serve as a novel prognostic biomarker for CESC *** further focused on CCL5 as a hub gene in CESC,as it had significant correlations with increased numbers of several ty.es of immune ***-ty.e fractions of M1 macrophages were significantly.h.gher in the high-immune-scores group,which was associated with better overall ***,we concluded that CCL5 is a promising prognostic biomarker for CESC,as well as a novel chemotherapeutic target.

关键词： TCGA Immune scores Prognosis Cervical cancer

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北京地区雷电灾害天气系统的动力-微物理-电过程观测研究

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中国科学：地球科学 2021年第1期51卷 46-62页

作者：郄秀书袁善锋陈志雄王东方刘冬霞孙萌宇孙竹玲 Abhay.SRIVASTAVA 张鸿波卢晶雨肖辉毕永恒冯亮田野徐燕蒋如斌刘明远肖现段树苏德斌孙成云徐文静张义军陆高鹏 Da-Lin ZhANG 银燕余晔中国科学院大气物理研究所中层大气和全球环境探测重点实验室(LAGEO) 北京100029 中国科学院大气物理研究所云降水物理与强风暴重点实验室(LACS) 北京100029 中国气象局北京城市气象研究所北京100089 成都信息工程大学电子工程学院成都610225 中国气象科学研究院灾害天气国家重点实验室北京100081 南京信息工程大学中国气象局气溶胶-云-降水重点实验室南京210044 中国科学院西北生态环境资源研究院寒旱区陆面过程与气候变化重点实验室兰州730000 中国科学院大学地球与行星科学学院北京100049 复旦大学大气与海洋科学系上海200438 北京市气象局气象探测中心北京100081 江西省人工影响天气领导小组办公室南昌330096 Department of Atmospheric and Oceanic Science University of MarylandMaryland 20742USA

在国家"973"项目"雷电重大灾害天气系统的动力-微物理-电过程和成灾机理"(简称:雷暴973)资助下,2014~2018年连续五年在北京组织开展了雷电(也称闪电)灾害天气系统的暖季综合协同观测实验,旨在获得对北京及周边城市群区域的雷电天气系统... 详细信息

在国家"973"项目"雷电重大灾害天气系统的动力-微物理-电过程和成灾机理"(简称:雷暴973)资助下,2014~2018年连续五年在北京组织开展了雷电(也称闪电)灾害天气系统的暖季综合协同观测实验,旨在获得对北京及周边城市群区域的雷电天气系统特征和规律的实际认识,探索雷电资料在数值预报模式中的同化方法,以期改进雷电重大灾害天气系统的预报效果.主要观测设备包括:由16个子站构成的雷电(全闪)三维定位系统、2台x.段双线偏振多普勒雷达和4台激光雨滴谱仪等,协同观测还充分利用了中国气象局在京津冀地区的中尺度气象观测网.观测结果表明,受地形和环境条件影响,飑线和多单体雷暴是影响北京地区的两类主要的雷电灾害天气系统,它们除产生频繁的雷电活动外,还常伴随突发性局地短时强降水和冰雹,造成城区突发洪涝灾害.雷电密度的高值区位于北京昌平区东部、顺义区的中部和东部以及中心城区.超强雷暴(占总雷暴数的5%)、强雷暴(占比35%)和弱雷暴(占比60%)对总雷电分布的贡献分别为37%、56%和7%.北京城区的热岛效应对过境雷暴增强产生了重要作用,超强雷暴在中心城区的雷电频数可以高达每分钟数百次.雷电活动与雷暴云的热动力、微物理特征之间存在紧密联系,因此雷电频数可以作为冰雹、短时强降水等灾害性天气的指示因子.在对流可分辨数值预报模式中,建立并引入雷电资料同化方案,通过调整或修正模式的热动力和微物理参量,可明显提高模式对强对流和降水的预报效果.

关键词：雷电(全闪)三维定位双线偏振多普勒雷达雷电灾害天气系统雷电资料同化冰雹短时强降水

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