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Multidisciplinary team therapy for left giant adrenocortical carcinoma: A case report

World Journal of Clinical Cases 2021年第20期9卷 5737-5743页

作者： Zheng Zhou Hong-Mei Luo Jian Tang wu-jun xu Bin-Hui Wang xu-Hui Peng Heng Tan Li Liu Xiang-Yang Long Yu-De Hong Xiao-Bin wu Jian-Ping Wang Bai-Qi Wang Hai-Hui Xie Yong Fang Yong Luo Rong Li Yi Wang Department of Urology The Second Affiliated HospitalUniversity of South ChinaHengyang 421001Hunan ProvinceChina Department of Histology and Embryology Clinical Anatomy and Reproductive Medicine Application InstituteUniversity of South ChinaHengyang 421001Hunan ProvinceChina Department of Endocrinology The Second Affiliated Hospital of University of South ChinaHengyang 421001Hunan ProvinceChina Department of Oncology The Second Affiliated HospitalUniversity of South ChinaHengyang 421001Hunan ProvinceChina Department of Radiotherapy The Second Affiliated HospitalUniversity of South ChinaHengyang 421001Hunan ProvinceChina Department of Pathology The Second Affiliated HospitalUniversity of South ChinaHengyang 421001Hunan ProvinceChina Department of ICU The Second Affiliated HospitalUniversity of South ChinaHengyang 421001Hunan ProvinceChina Department of Clinical Pharmacy The Second Affiliated HospitalUniversity of South ChinaHengyang 421001Hunan ProvinceChina

BACKGROUND Adrenocortical carcinoma(ACC)is a rare malignant epithelial tumor originating from adrenocortical cells that carries a very poor prognosis.Metastatic or inoperable diseases are often considered incurable,and treatment remains a challenge.Especially for advanced cases such as ACC complicated with renal venous cancer thrombus,there are few cumulative cases in the literature.CASE SUMMARY The patient in this case was a 39-year-old middle-aged male who was admitted to the hospital for more than half a month due to dizziness and chest tightness.Computed tomography(CT)findings after admission revealed a left retroperitoneal malignant space-occupying lesion,but the origin of the formation of the left renal vein cancer thrombus remained to be determined.It was speculated that it originated from the left adrenal gland,perhaps a retroperitoneal source,and left adrenal mass+left nephrectomy+left renal vein tumor thrombus removal+angioplasty were performed under general anesthesia.Postoperative pathology results indicated a diagnosis of ACC.Postoperative steroid therapy was administered.At 3 mo after surgery,abdominal CT reexamination revealed multiple enlarged retroperitoneal lymph nodes and multiple low-density shadows in the liver,and palliative radiotherapy and mitotane were administered,considering the possibility of metastasis.The patient is currently being followed up.CONCLUSION ACC is a highly malignant tumor.Even if the tumor is removed surgically,there is still the possibility of recurrence.Postoperative mitotane and adjuvant chemoradiotherapy have certain benefits for patients,but they cannot fully offset the poor prognosis of this disease.

关键词： Adrenocortical carcinoma Ki-67 Multidisciplinary team Cancer thrombus Mitotane Case report

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Macroscopic model and statistical model to characterize electromagnetic information of a digital coding metasurface

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National Science Review 2024年第3期11卷 159-171页

作者： Rui Wen Shao jun Wei wu Zheng Xing Wang Hui xu Han Qing Yang Qiang Cheng Tie jun Cui Institute of Electromagnetic Space Southeast University State Key Laboratory of Millimeter Waves Southeast University Peng Cheng Laboratory Pazhou Laboratory(Huangpu)

A digital coding metasurface is a platform connecting the digital space and electromagnetic wave space, and has therefore gained much attention due to its intriguing value in reshaping wireless channels and realizing new communication architectures. Correspondingly, there is an urgent need for electromagnetic information theory that reveals the upper limit of communication capacity and supports the accurate design of metasurface-based communication systems. To this end, we propose a macroscopic model and a statistical model of the digital coding metasurface. The macroscopic model uniformly accommodates both digital and electromagnetic aspects of the meta-atoms and predicts all possible scattered fields of the digital coding metasurface based on a small number of simulations or measurements. Full-wave simulations and experimental results show that the macroscopic model is feasible and accurate. A statistical model is further proposed to correlate the mutual coupling between meta-atoms with covariance and to calculate the entropy of the equivalent currents of digital coding metasurface. These two models can help reconfigurable intelligent surfaces achieve more accurate beamforming and channel estimation, and thus improve signal power and coverage. Moreover, the models will encourage the creation of a precoding codebook in metasurface-based direct digital modulation systems, with the aim of approaching the upper limit of channel capacity. With these two models, the concepts of current space and current entropy, as well as the analysis of information loss from the coding space to wave space, is established for the first time, helping to bridge the gap between the digital world and the physical world, and advancing developments of electromagnetic information theory and new-architecture wireless systems.

关键词： electromagnetic information theory current entropy current space digital coding metasurface macroscopic model statistical model

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Mirizzi syndrome:Problems and strategies

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Hepatobiliary & Pancreatic Diseases International 2024年第3期23卷 234-240页

作者： jun wu Shuang-Yong Cai xu-Liang Chen Zhi-Tao Chen Shao-Hua Shi Department of Hepatobiliary and Pancreatic Surgery People’s Hospital of Jiulongpo DistrictChongqing 400050China Department of Hepatobiliary and Pancreatic Surgery Shulan(Hangzhou)Hospital Affiliated to Zhejiang Shuren University Shulan International Medical CollegeHangzhou 310003China

Mirizzi syndrome is a serious complication of gallstone disease.It is caused by the impacted stones in the gallbladder neck or cystic duct.One of the features of Mirizzi syndrome is severe inflammation or dense fibrosis at the Calot’s triangle.In our clinical practice,bile duct,branches of right hepatic artery and right portal vein clinging to gallbladder infundibulum are often observed due to gallbladder infundibulum adhered to right hepatic hilum.The intraoperative damage of branches of right hepatic artery occurs more easily than that of bile duct,all of which are hidden pitfalls for surgeons.Magnetic resonance cholangiopancreatography(MRCP)and endoscopic retrograde cholangiopancreatography(ERCP)are the preferable tools for the diagnosis of Mirizzi syndrome.Anterograde cholecystectomy in Mirizzi syndrome is easy to damage branches of right hepatic artery and bile duct due to gallbladder infundibulum adhered to right hepatic hilum.Subtotal cholecystectomy is an easy,safe and definitive approach to Mirizzi syndrome.When combined with the application of ERCP,a laparoscopic management of Mirizzi syndrome by well-trained surgeons is feasible and safe.The objective of this review was to highlight its existing problems:(1)low preoperative diagnostic rate,(2)easy to damage bile duct and branches of right hepatic artery,and(3)high concomitant gallbladder carcinoma.Meanwhile,the review aimed to discuss the possible therapeutic strategies:(1)to enhance its preoperative recognition by imaging findings,and(2)to avoid potential pitfalls during surgery.

关键词： Mirizzi syndrome Bile duct injury Artery injury Surgical treatment Subtotal cholecystectomy

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Effect of proppant sizes and injection modes on proppant transportation and distribution in the tortuous fracture model

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Particuology 2024年第1期84卷 261-280页

作者： jun Li xu Han Siyuan He Mingyi wu Xin Huang Nianyin Li State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Southwest Petroleum UniversityChengdu610500China Chongqing Industry Polytechnic College Chongqing401120China Sichuan Particles Energy and Technology Co. LtdChengdu611630China Engineering Technology Research Institute of PetroChina Southwest Oil and Gas Field Company Chengdu610017China

Particle-fluid transport and placement mechanism in tortuous fracture played a crucial role in uncon-ventional reservoirs.Currently,most studies focused on mono-size proppant with fluid transport pro-cesses in tortuous fractures.However,the mixture-size proppant with fluid movement mechanism in tortuous fracture was still uncommon.Therefore,this study designed and applied a series of experiments with a physical analog model of a tortuous fracture with 120°and 90°-angled bends and combined high-speed camera-based equipment.This experimental system was used to track different-mixture-sized proppant particle motion trajectories for a series of proppant injection schemes;The following conclu-sions were drawn from this study:1.The pile-up processes mechanism in all investigated schemes were similar and could be reduced to four main stages.2.The packing structure at both sides of the fracture wall had different variation rates,which were controlled by the mix ratio(change from 1∶1-1∶5)of proppant size.3.Some new packing patterns,such as Zebra Stripe,had occurred,controlled by the different proppant injection sequences.4.Small-sized mono-proppant(30/50 mesh)had the highest transport efficiency in the tortuous fracture,followed by the mixed-sized multi-proppant(10/20 mesh:30/50 mesh),large-sized proppant(10/20 mesh)was the worst.5.An optimized alternating in-jection mode was recommended as injecting small-sized proppant first(30/50 mesh)and followed by mixed-sized multi-proppant(10/20 mesh:30/50 mesh),which could contribute to obtaining the optimal both proppant packing height and travel distance in tortuous fracture.6.Two correlations were devel-oped for predicting the proppant packing height and transportation distance.

关键词： Tortuous fracture model Mixed-sized proppant Multi-sized proppant injection mode Proppant motion and distribution Packing mechanism

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The nature of electron density enhancement over a wide altitude range during ionosphere heating experiments at EISCAT

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Earth and Planetary Physics 2024年第2期8卷 408-414页

作者： jun wu Jian wu Jie Feng QingLiang Li ShuJi Hao ZhengWen xu HaiSheng Zhao YaBin Zhang National Key Laboratory of Electromagnetic Environment China Research Institute of Radio Wave PropagationBeijing 102206China School of Physics Xidian UniversityXi’an 710071China

During the course of ionospheric heating experiments, researchers at the European Incoherent Scatter Scientific Association (EISCAT) observed an apparent electron density enhancement. The enhancement extended over a wide range of altitudes, above the reflection altitude of the high-frequency pump wave. However, whether this enhancement actually corresponds to a true enhancement in electron density remains an open question. When the dispersion relation of ion acoustic waves is followed, the frequency ratio of the enhanced ion line to the background ion line suggests that the profile of the effective ion mass may have remained unchanged. Furthermore, the solar radio flux and ion drift velocity indicate no significant changes in the ion species and their densities. In conclusion, the electron density enhancement observed at EISCAT should not, in fact, be considered a true enhancement.

关键词： incoherent scatter radar(ISR) ionospheric heating electron density ion acoustic wave

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Nd:YAG water mist laser treatment for giant gestational gingival tumor: A case report

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World Journal of Clinical Cases 2024年第11期12卷 1974-1979页

作者： Hong-Yu Chen jun-Ji xu Xiu-Lin Chang Pei wu Department of Stomatology Women and Children's Hospital Affiliated to Ningbo UniversityNingbo 315012Zhejiang ProvinceChina

BACKGROUND This case of gestational gingival tumor is huge and extremely rare in clinical practice.As the growth location of this gingival tumor is in the upper anterior tooth area,it seriously affects the pregnant woman's speech and food,causing great pain to the patient.The use of Nd:YGA water mist laser to remove the gingival tumor resulted in minimal intraoperative bleeding,minimal adverse reactions,and good postoperative healing,which is worthy of clinical promotion and application.CASE SUMMARY The patient,a pregnant woman,reported a large lump in her mouth on the first day of postpartum treatment.Based on medical history and clinical examination,the diagnosis was diagnosed as gestational gingival tumor.Postoperative pathological biopsy also confirmed this diagnosis.The use of Nd:YAG water mist laser to remove the tumor resulted in minimal intraoperative bleeding,clear surgical field of view,short surgical time,and good postoperative healing.CONCLUSION In comparison to traditional surgery,Nd:YAG water mist laser surgery is minimally invasive,minimizes cell damage,reduces bleeding,ensures a clear field of vision,and virtually eliminates postoperative edema,carbonization,and the risk of cross infection.It has unique advantages in oral soft tissue surgery for pregnant patients.Therefore,the clinical application of Nd:YAG water mist laser for the treatment of gestational gingival tumors is an ideal choice.

关键词： Gestational gingival tumor Nd:YAG water mist laser Granulomatous gingival tumor Minimally invasive dentistry Pregnancy related diseases Oral soft tissue surgery Case report

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Sustainable, thermoplastic and hydrophobic coating from natural cellulose and cinnamon to fabricate eco-friendly catering packaging

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Green Energy & Environment 2024年第5期9卷 927-936页

作者： Rumeng xu Chunchun Yin Jingxuan You Jinming Zhang Qinyong Mi Jin wu jun Zhang CAS Key Laboratory of Engineering Plastics Institute of ChemistryChinese Academy of Sciences(CAS)Beijing100190China University of Chinese Academy of Sciences Beijing100049China

Non-degradable polymers cause serious environmental pollution problem,such as the widely-used while unrecyclable coatings which signiﬁcantly affect the overall degradation performance of products.It is imperative and attractive to develop biodegradable functional coatings.Herein,we proposed a novel strategy to successfully prepare biodegradable,thermoplastic and hydrophobic coatings with high transparence and biosafety by weakening the interchain interactions between cellulose chain.The natural cellulose and cinnamic acid were as raw materials.Via reducing the degree of polymerization(DP)of cellulose and regulating the degree of substitution(DS)of cinnamate moiety,the obtained cellulose cinnamate(CC)exhibited not only the thermalﬂow behavior but also good biodegradability,which solves the conﬂict between the thermoplasticity and biodegradability in cellulose-based materials.The glass transition temperature(T_(g))and thermalﬂow temperature(T_(f))of the CC could be adjusted in a range of 150–200℃ and 180–210℃,respectively.The CC with DS<1.2 and DP≤100 degraded more than 60%after an enzyme treatment for 7 days,and degraded more than 80%after a composting treatment for 42 days.Furthermore,CC had no toxicity to human epidermal cells even at a high concentration(0.5 mg mL^(-1)).In addition,CC could be easily fabricated into multifunctional coating with high hydrophobicity,thermal adhesion and high transparence.Therefore,after combining with cellophane and paperboard,CC coating with low DP and DS could be used to prepare fully-biodegradable heat-sealing packaging,art paper,paper cups,paper straws and food packaging boxes.

关键词： Thermoplastic coating Bio-degradable adhesive Natural products Cellulose Eco-friendly packaging

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Experimental study of the damage characteristics of rocks containing non-penetrating cracks under cyclic loading

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International Journal of Mining Science and Technology 2024年第2期34卷 197-210页

作者： jun xu Xiaochun Xiao Lu Ma Sen Luo Jiaxu Jin Baijian wu School of Mechanics and Engineering Liaoning Technical UniversityFuxin 123000China School of Civil Engineering Liaoning Technical UniversityFuxin 123000China Department of Engineering Mechanics Southeast UniversityNanjing 211189China

The damage evolution process of non-penetrating cracks often causes some unexpected engineering disasters.Gypsum specimens containing non-penetrating crack(s)are used to study the damage evolution and characteristics under cyclic loading.The results show that under cyclic loading,the relationship between the number of non-penetrating crack(s)and the characteristic parameters(cyclic number,peak stress,peak strain,failure stress,and failure strain)of the pre-cracked specimens can be represented by a decreasing linear function.The damage evolution equation is fitted by calibrating the accumulative plastic strain for each cycle,and the damage constitutive equation is proposed by the concept of effective stress.Additionally,non-penetrating cracks are more likely to cause uneven stress distribution,damage accumulation,and local failure of specimen.The local failure can change the stress distribution and relieve the inhibition of non-penetrating crack extension and eventually cause a dramatic destruction of the specimen.Therefore,the evolution process caused by non-penetrating cracks can be regarded as one of the important reasons for inducing rockburst.These results are expected to improve the understanding of the process of spalling formation and rockburst and can be used to analyze the stability of rocks or rock structures.

关键词： Damage characteristics Constitutive model Fissured rocks Non-penetrating crack Cyclic loading

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CNN-LSTM based incremental attention mechanism enabled phase-space reconstruction for chaotic time series prediction

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Journal of Electronic Science and Technology 2024年第2期22卷 77-90页

作者： Xiao-Qian Lu jun Tian Qiang Liao Zheng-wu xu Lu Gan Bidding and Purchasing Center University of Electronic Science and Technology of ChinaChengdu611731China Yibin Research Institute University of Electronic Science and Technology of ChinaYibin644000China School of Information and Communication Engineering University of Electronic Science and Technology of ChinaChengdu611731China

To improve the prediction accuracy of chaotic time series and reconstruct a more reasonable phase space structure of the prediction network,we propose a convolutional neural network-long short-term memory(CNN-LSTM)prediction model based on the incremental attention mechanism.Firstly,a traversal search is conducted through the traversal layer for finite parameters in the phase space.Then,an incremental attention layer is utilized for parameter judgment based on the dimension weight criteria(DWC).The phase space parameters that best meet DWC are selected and fed into the input layer.Finally,the constructed CNN-LSTM network extracts spatio-temporal features and provides the final prediction results.The model is verified using Logistic,Lorenz,and sunspot chaotic time series,and the performance is compared from the two dimensions of prediction accuracy and network phase space structure.Additionally,the CNN-LSTM network based on incremental attention is compared with long short-term memory(LSTM),convolutional neural network(CNN),recurrent neural network(RNN),and support vector regression(SVR)for prediction accuracy.The experiment results indicate that the proposed composite network model possesses enhanced capability in extracting temporal features and achieves higher prediction accuracy.Also,the algorithm to estimate the phase space parameter is compared with the traditional CAO,false nearest neighbor,and C-C,three typical methods for determining the chaotic phase space parameters.The experiments reveal that the phase space parameter estimation algorithm based on the incremental attention mechanism is superior in prediction accuracy compared with the traditional phase space reconstruction method in five networks,including CNN-LSTM,LSTM,CNN,RNN,and SVR.

关键词： Chaotic time series Incremental attention mechanism Phase-space reconstruction

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Bioinspired Stretchable MXene Deformation-Insensitive Hydrogel Temperature Sensors for Plant and Skin Electronics

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Research 2024年第1期2023卷 389-401页

作者： jun wu Yinghui Li Shengshun Duan Zhehan Wang xu Jing Yucheng Lin Di Zhu Wei Lei Qiongfeng Shi Li Tao Joint International Research Laboratory of Information Display and Visualization School of Electronic Science and EngineeringSoutheast UniversityNanjingJiangsu 210096China School of Materials Science and Engineering Southeast UniversityNanjingJiangsu 210096China Center of 2D Materials and Devices Southeast UniversityNanjingJiangsu 210096China

Temperature sensing is of high value in the wearable healthcare,robotics/prosthesis,and noncontact physiological monitoring.However,the common mechanic deformation,including pressing,bending,and stretching,usually causes undesirable feature size changes to the inner conductive network distribution of temperature sensors,which seriously influences the accuracy.Here,inspired by the transient receptor potential mechanism of biological thermoreceptors that could work precisely under various skin contortions,we propose an MXene/Clay/poly(N-isopropylacrylamide)(PNIPAM)(MCP)hydrogel with high stretchability,spike response,and deformation insensitivity.The dynamic spike response is triggered by the inner conductive network transformation from the 3-dimensional structure to the 2-dimensional surface after water being discharged at the threshold temperature.The water discharge is solely determined by the thermosensitivity of PNIPAM,which is free from mechanical deformation,so the MCP hydrogels can perform precise threshold temperature(32℃)sensing under various deformation conditions,i.e.,pressing and 15%stretching.As a proof of concept,we demonstrated the applications in plant electronics for the real-time surface temperature monitoring and skin electronics for communicating between human and machines.Our research opens venues for the accurate temperature-threshold sensation on the complicated surface and mechanical conditions.

关键词： stretching proof precise

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