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Traditional Use,Phytochemistry,Pharmacology,Toxicology and Clinical Applications of Persicae Semen:A Review

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Chinese Journal of Integrative Medicine 2024年第12期30卷 1137-1147页

作者： liU Yu-quan wu hui-li ZHANG Zhi-qiang WANG Wen-le HAN Guo-qing ZHANG Chun-hong LYU Xin-liang MA Chun-jie li Min-hui School of Traditional Chinese Medicine Inner Mongolia Medical UniversityHohhot 010000China Department of Rheumatology Inner Mongolia Autonomous Region Hospital of Traditional Chinese MedicineHohhot 010020China School of Pharmacy Baotou Medical CollegeBaotou 014040China Infectious Disease Department Hohhot Mongolian Medicine of Traditional Chinese Medicine HospitalHohhot 010000China

Persicae Semen(Taoren),the seed of mature peaches consumed as both food and medicine,is native to the temperate regions of China,distributed in the provinces of North and East China,and currently cultivated *** primary components of Persicae Semen include volatile oil,protein,amino acids,amygdalin,and prunasin,all of which have pharmacological properties,such as anti-inflammatory,antioxidant,and immune regulatory effects,and are clinically used in the treatment of gynecological,cardiovascular,cerebrovascular,orthopedic,and digestive system *** review provides a comprehensive perspective on the resource status,ethnopharmacology,phytochemistry,pharmacology,and toxicology,as well as the trend of Persicae Semen patent,global distribution,and clinical *** review will help facilitate the development and utilization of Persicae Semen in clinical settings.

关键词： Persicae Semen phamacology clinical applications food-medicine homology phytochemistry review

Delayed right-sided diaphragmatic hernia with severe ：raniocerebral trauma

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Chinese Medical Journal 2010年第7期123卷 974-976页

作者： TANG Hua wu li-hui li Jian-qiu XU Zhi-fei Department of Thoracic and Cardiovascular Surgery Shanghai Changzheng Hospital Second Military Medical University Shanghai 200003 China

Diaphragmatic hernia （DH） is an uncommon result of trauma, but presents a severe problem in patients With multiple injuries. Right-sided DH is rare, owing to the protection of the liver and strength of the right hem... 详细信息

关键词： trauma diaphragmatic hernia craniocerebral trauma

Regulating Effects of Novel CpG Chitosan-nanoparticles on Immune Responses of Mice to Porcine Paratyphoid Vaccines

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Biomedical and Environmental Sciences 2006年第4期19卷 315-322页

作者： MAN-liANG FU SAN-CHENG YING MEI wu hui li KAI-YUAN wu YI YANG HUAN ZHANG CHI CHENG ZE-ZHOU WANG XIU-YING WANG XUE-BING LV YI-ZHENG ZHANG RONG GAO Key Lab. for Bio-Resource and Eco-Environment of Education Ministry Life Science College Sichuan University Chengdu 610064 Sichuan China

Objective To study the regulating effects of a novel CpG oligodeoxynuleotide and the synergistic effect of chitosan-nanoparticles （CNP） with CpG on immune responses of mice, which were used to develop a novel immunoadjuvant to boost immune response to conventional vaccines. Methods A novel CpG ODN containing 11 CpG motifs was synthesized and its bioactivities to stimulate the proliferation of lymphocytes of pig in vitro were detected. Then it was entrapped with CNP prepared in our laboratory by the method of ionic cross linkage, and immunized Kunming mice were co-inoculated with paratyphoid vaccine. The peripheral blood was collected weekly from the tail vein of inoculated mice to detect the contents of IgG, IgA, IgM, and specific antibody against salmonella as well as the levels of interleukin-2 （IL2）, IL-4, and IL-6 by SABC-EliSA assay. The numbers of leucocytes, monocytes, granuloytes, and lymphocytes were calculated separately using the routine method. The experimental mice were orally challenged with virulent salmonella 35 days after inoculation. Results This CpG ODN could remarkably provoke the proliferation of lymphocytes of pig in vitro in contrast with the control （P〈0.05）. Compared with those of the control, immunoglobulins, including IgG, IgA, IgM, and specific antibodies to paratyphoid vaccine, increased significantly in sera from the CpG or CpG-CNP-vaccinated mice （P〈0.05）. IL-2, IL-4, and IL-6 increased remarkably in sera from immunized mice （P〈0.05）. The leucocytes, monocytes, granuloytes, and lymphocytes of the mice immunized with CpG or CpG-CNP were also increased in number （P〈0.05）. After the challenge, these immunity values were elevated in the mice vaccinated with CpG or CpG-CNP. The immunized mice all survived, while the control mice fell ill with evident lesions with diffuse hemorrhage in stomach, small intestine, and peritoneum. Conclusions CpG ODN entrapped with CNP is a promising effective immunoadjuvant for vaccination, which promotes humor

关键词： CpG oligonucleotide Mice Immune responses CNP Paratyphoid vaccine

Plasmonic tandem heterojunctions enable high-efficiency charge transfer for broad spectrum photocatalytic hydrogen production

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Journal of Energy Chemistry 2025年第1期100卷 710-720页

作者： Wenxuan Chen Xiu-Qing Qiao Guo hui Bojing Sun Dongfang Hou Meidi Wang Xueqian wu Tao wu Dong-Sheng li College of Materials and Chemical Engineering Key Laboratory of Inorganic Nonmetallic Crystalline and Energy Conversion Materials China Three Gorges University Hubei Three Gorges Laboratory College of Chemistry and Materials Science and Guangdong Provincial Key Laboratory of Supramolecular Coordination Chemistry Jinan University

Rational engineering of semiconductor photocatalysts for efficient hydrogen production is of great significance but still challenging,primarily due to the limitations in charge transfer ***,a fascinating plasmonic tandem heterojunction with the hc-CdS/Mo2C@C heterostructure is aimfully prepared for effectively promoting the charge separation kinetics of the CdS photocatalyst via the synergistic strategy of phase junction,Schottky junction,and photothermal *** difference in atomic configuration between cubic-CdS （c-CdS） and hexagonal-CdS （h-CdS） leads to effective charge separation through a typical Ⅱ charge transfer mechanism,and plasmonic Schottky junction further extracts the electrons in the hc-CdS phase junction to realize gradient charge ***,the photothermal effect of Mo2C@C helps to expand the light absorption,accelerate charge transfer kinetics,and reduce the hydrogen evolution energy *** carbon layer provides a fast channel for charge transfer and protects the photocatalyst from *** a result,the optimized hc-CMC photocatalyst exhibits a significantly high photocatalytic H2production activity of 28.63 mmol/g/h and apparent quantum efficiency of 61.8%,surpassing most of the reported *** study provides a feasible strategy to enhance the charge transfer kinetics and photocatalytic activity of CdS by constructing plasmonic tandem heterogeneous junctions.

关键词： Cadmium sulfide

Decoding the nexus:branched-chain amino acids and their connection with sleep,circadian rhythms,and cardiometabolic health

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Neural Regeneration Research 2025年第5期20卷 1350-1363页

作者： hui li Laurent Seugnet Department of Neurology Xijing HospitalXi’anShaanxi ProvinceChina Centre de Recherche en Neurosciences de Lyon Integrated Physiology of the Brain Arousal Systems(WAKING)UniversitéClaude Bernard Lyon 1INSERM U1028CNRS UMR 5292BronFrance

The sleep-wake cycle stands as an integrative process essential for sustaining optimal brain function and,either directly or indirectly,overall body health,encompassing metabolic and cardiovascular *** the heightened metabolic activity of the brain,there exists a considerable demand for nutrients in comparison to other *** these,the branched-chain amino acids,comprising leucine,isoleucine,and valine,display distinctive significance,from their contribution to protein structure to their involvement in overall metabolism,especially in cerebral *** the first amino acids that are released into circulation post-food intake,branched-chain amino acids assume a pivotal role in the regulation of protein synthesis,modulating insulin secretion and the amino acid sensing pathway of target of ***-chain amino acids are key players in influencing the brain's uptake of monoamine precursors,competing for a shared *** their involvement in protein synthesis,these amino acids contribute to the metabolic cycles ofγ-aminobutyric acid and glutamate,as well as energy ***,they impact GABAergic neurons and the excitation/inhibition *** rhythmicity of branchedchain amino acids in plasma concentrations,observed over a 24-hour cycle and conserved in rodent models,is under circadian clock *** mechanisms underlying those rhythms and the physiological consequences of their disruption are not fully *** sleep,obesity,diabetes,and cardiovascular diseases can elevate branched-chain amino acid concentrations or modify their oscillatory *** mechanisms driving these effects are currently the focal point of ongoing research efforts,since normalizing branched-chain amino acid levels has the ability to alleviate the severity of these *** this context,the Drosophila model,though underutilized,holds promise in shedding new light on these *** findings indicate its po

关键词： branched-chain amino acids cardiovascular health circadian clock drosophila insulin metabolism sleep γ-aminobutyric acid

基于多代理的知识有色赋时Petri网的晶圆制造系统建模方法

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计算机集成制造系统 2009年第10期15卷 1921-1929页

作者：吴立辉张洁上海交通大学计算机集成制造研究所上海200240

为了对大规模、复杂的晶圆制造系统进行有效建模,提出了基于多代理的知识有色赋时Petri网的晶圆制造系统分层建模方法。在设备层,对晶圆制造系统的系统资源、内部行为和知识进行封装,建立了设备层代理模型。在设备组层和系统层,根据系... 详细信息

为了对大规模、复杂的晶圆制造系统进行有效建模,提出了基于多代理的知识有色赋时Petri网的晶圆制造系统分层建模方法。在设备层,对晶圆制造系统的系统资源、内部行为和知识进行封装,建立了设备层代理模型。在设备组层和系统层,根据系统需求对各设备组内部及其之间的关系进行配置,分别建立了设备层和系统层代理模型。该方法提高了模型的可配置和重用性,降低了建模的复杂性,同时将知识与模型的库所和变迁集成,增强了模型的运行决策能力。通过上海某企业的150 mm晶圆的生产数据验证,证明了基于多代理的知识有色赋时Petri网的晶圆制造系统模型的有效性。

关键词：代理晶圆制造系统 Petri网建模

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晶圆制造物料运输系统性能分析建模方法

计算机集成制造系统 2013年第8期19卷 2043-2049页

作者：吴立辉张洁河南工业大学机电工程学院河南郑州450007 上海交通大学机械与动力工程学院上海200240

为在自动化物料搬运系统设计阶段快速有效地分析该系统的性能,提出一种扩展Markov模型的建模方法,该方法减少了自动化物料搬运系统性能分析模型的规模,避免了模型的状态空间规模爆炸。采用某晶圆制造企业的实际生产数据进行测试,并与仿... 详细信息

为在自动化物料搬运系统设计阶段快速有效地分析该系统的性能,提出一种扩展Markov模型的建模方法,该方法减少了自动化物料搬运系统性能分析模型的规模,避免了模型的状态空间规模爆炸。采用某晶圆制造企业的实际生产数据进行测试,并与仿真分析方法比较。结果表明,扩展Markov模型与仿真模型在自动化物料搬运系统搬运量、运输小车利用率和空载小车到达平均时间间隔等指标方面的相对误差值为96%,处于[-8%,10%]的区间范围;与仿真模型相比,扩展Markov模型的性能分析效率提高了600倍以上。由此验证了所提扩展Markov模型建模方法的有效性。

关键词：晶圆制造自动化物料运输系统建模扩展Markov模型

MoS2 synaptic transistor with one-step manufacture

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Science China(Information Sciences) 2025年第1期68卷 357-365页

作者： Yihao GUO Yang WANG Wenjie DENG Yi wu Jingtao li Kexin li Yuehui ZHAO Songlin YU Xiaoting WANG Yongzhe ZHANG hui YAN Key Laboratory of Optoelectronics Technology of Education Ministry of China Faculty of Information TechnologyBeijing University of Technology Key Laboratory of Advanced Functional Materials Ministry of Education Faculty of Materials and ManufacturingBeijing University of Technology The 11th Research Institute of Electronics Technology Group Corporation

The synaptic transistor,which is a neuromorphic device with brain-like functions,has garnered significant attention due to characteristics such as low energy consumption,high integration,multiple functions,and high computational ***,the current synaptic transistor possesses a complicated structure and involves complex manufacturing steps,which is not conducive to low-cost,large-scale bionic ***,we introduce a simple MoS2synaptic transistor exhibiting robust synaptic *** transistor utilizes magnetron sputtering manufacture to combine the process of device metal electrode deposition and the introduction of defect states,which helps streamline the manufacturing process into a single *** long-term potentiation and long-term depression in photoelectric coordination are initially ***,biological functions,such as double pulse facilitation and the transformation behavior of short-term memory to long-term memory,are thoroughly evaluated,along with learning-forgetting-relearning ***,the device exhibits robust synaptic plasticity until incident light angles down to 30° to imitate the multi-to-one axon-cellular ***,a classical simulation of Pavlov's dog conditioned reflex is demonstrated along with the multiview extraction *** experimental results demonstrate a promising synaptic transistor with a simple structure,manufacturing technique,and excellent *** further indicates the potential for large-scale integration of bionic neuromorphic systems.

关键词： process optimization artificial synaptic device one-stepmanufacture synaptic plasticity bionic simulation

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基于排队网络的晶圆制造自动化物料运输系统性能模型

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计算机集成制造系统 2014年第9期20卷 2267-2274页

作者：朱登洁吴立辉武汉理工大学机电工程学院湖北武汉430070 河南工业大学机电工程学院河南郑州450007

为快速有效地分析晶圆制造自动化物料运输系统的性能,以获得优化的系统设计方案,提出一种基于排队网络的性能分析模型。该模型考虑多运输小车的堵塞特性,将运输小车运行过程等效为排队网络过程,并采用虚拟元对自动化物料运输系统的捷径... 详细信息

为快速有效地分析晶圆制造自动化物料运输系统的性能,以获得优化的系统设计方案,提出一种基于排队网络的性能分析模型。该模型考虑多运输小车的堵塞特性,将运输小车运行过程等效为排队网络过程,并采用虚拟元对自动化物料运输系统的捷径导轨特性进行描述,提高了性能分析模型的准确性。采用某晶圆制造企业的实际生产数据进行实验,并与仿真模型进行比较。结果表明:基于排队网络的性能分析模型与仿真模型在运输小车利用率、AMHS搬运能力和空载小车到达平均时间间隔等指标方面的相对误差值97%处于[-7%,9%]的区间范围,且比仿真模型具有更高的计算效率。

关键词：晶圆制造自动化物料运输系统性能分析模型排队网络