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The End of the Supersensory World＇s Mythology： Marx＇s Ontological Revolution and Its Contemporary Significance

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Frontiers of Philosophy in China 2012年第1期7卷 128-141页

作者： wu xiaoming Department of Philosophy Fudan UniversityShanghai 200433China

The whole of Western metaphysics, particularly Platonism, sets up a partition between the sensory world and the supersensory world, laying the foundation for the mythology of the supersensory world. After Descartes set contemporary metaphysics on its course, Feuerbach became the first to attack the essence of the supersensory world on an ontological level and to transfer the criticism of theology to that of metaphysics in general. While in the final analysis Feuerbach＇s criticism fails, Marx＇s revolution appeals to the ontological notion of ＂sensory activity＂ or ＂objective activity＂（i.e., practice）, the core of which rests in piercing and overturning the fundamental framework of contemporary metaphysics--＂the immanence of consciousness.＂ It is this ontological revolution which reveals the camouflage of the supersensory world＇s mythology （i.e., ideology） and which simultaneously establishes a solid foundation for the critical analysis of the latter. Marx＇s ＂science of history＂ is based on this foundation and develops from it.

关键词： Marxist philosophy ontology supersensory world mythology ideological criticism

The characteristics of mRNA m^(6)A methylomes in allopolyploid Brassica napus and its diploid progenitors

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Horticulture Research 2023年第1期10卷 69-81页

作者： Zeyu Li Mengdi Li xiaoming wu Jianbo Wang State Key Laboratory of Hybrid Rice College of Life SciencesWuhan UniversityWuhan 430072HubeiChina Key Laboratory of Resource Biology and Biotechnology in Western China Ministry of EducationCollege of Life SciencesNorthwest UniversityXi’an 710069China Key Laboratory of Biology and Genetic Improvement of Oil Crops Ministry of AgricultureOil Crops Research Institute of CAASWuhan 430062China

Genome duplication events,comprising whole-genome duplication and single-gene duplication,produce a complex genomic context leading to multiple levels of genetic ***,the characteristics of m^(6)A modification,the most widespread internal eukaryotic mRNA modification,in polyploid species are still poorly *** study revealed the characteristics of m^(6)A methylomes within the early formation and following the evolution of allopolyploid Brassica *** found a complex relationship between m^(6)A modification abundance and gene expression level depending on the degree of enrichment or presence/absence of m^(6)A ***,the m^(6)A genes had lower gene expression levels than the non-m^(6)A *** may change the expression divergence of duplicated gene pairs with identical m^(6)A patterns and diverged m^(6)A *** with duplicated genes,singletons with a higher evolutionary rate exhibited higher m^(6)A *** kinds of duplicated genes exhibited distinct distributions of m^(6)A modifications in transcripts and gene expression *** particular,tandem duplication-derived genes showed unique m^(6)A modification enrichment around the transcript start *** histone modifications(H3K27ac and H3K4me3)but not DNA methylation were enriched around genes of m^(6)A *** findings provide a new understanding of the features of m 6A modification and gene expression regulation in allopolyploid plants with sophisticated genomic architecture.

关键词： polyp characteristics progenitor

Functional localization of the cortical motor area in the brain Electrocorticogram analysis

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Neural Regeneration Research 2010年第19期5卷 1480-1485页

作者： Tao Jiang xiaoming wu Binggang Ye Sijuan Huang School of Bioscience & Bioengineering South China University of Technology Guangzhou 510006 Guangdong Province China

The method for rapidly, precisely and non-invasively localizing functional regions of the brain is a problem in neuromedicine research. Cortical electrostimulation is the optimal localization method during brain surgery, with a degree of accuracy of approximately 5 mm. However, electrostimulation can damage the cerebral cortex, trigger epilepsy, and extend the operation time. Studies are required to determine whether cortical motor regions can be localized by wavelet analysis from electrocorticograms. In this study, based on wavelet analysis of electrocorticograms, a selection of algorithms for classification of the mu rhythm in the motor regions utilizing experimental data was verified. Results demonstrated that a characteristic quantity of energy ratio in the reconstructed signal was filtered in the d6 （7.81-15.62 Hz） band prior to and following motion events. A characteristic threshold was considered to be 40%. The accuracy of localization detection was 93%. The degree of accuracy was less than 5 mm. The present study avoided the problems of cerebral cortex injury and epilepsy onset, with an operation time of 60 seconds. Therefore, wavelet analysis on electrocorticogram is feasible for localizing cortical motor regions. Furthermore, this localization technique is accurate, safe and rapid.

关键词： functional localization electrocorticogram mu rhythm event-related desynchronization wavelet analysis neural regeneration

Evaluation of Genetic and Epigenetic Modification in Rapeseed(Brassica napus)Induced by Salt Stress

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Journal of Integrative Plant Biology 2007年第11期49卷 1599-1607页

作者： Guangyuan Lu xiaoming wu Biyun Chen Guizhen Gao Kun Xu Brassica Germplasm Division Oil Crops Research Institute Chinese Academy of Agricultural Science Wuhan 430062 China

Salinity is an important limiting environmental factor for rapeseed production worldwide. In this study, we assessed the extent and pattern of DNA damages caused by salt stress in rapeseed plants. Amplified fragment length polymorphism （AFLP） analysis revealed dose-related increases in sequence alterations in plantlets exposed to 10-1000 mmol/L sodium chloride. In addition, individual plantlets exposed to the same salt concentration showed different AFLP and selected region amplified polymorphism banding patterns. These observations suggested that DNA mutation in response to salt stress was random in the genome and the effect was dose-dependant. DNA methylation changes in response to salt stress were also evaluated by methylation sensitive amplified polymorphism （MSAP）. Three types of MSAP bands were recovered. Type Ⅰ bands were observed with both isoschizomers Hpa Ⅱ and Msp Ⅰ, while type Ⅱ and type Ⅲ bands were observed only with Hpa Ⅱ and Msp Ⅰ, respectively. Extensive changes in types of MSAP bands after NaCI treatments were observed, including appearance and disappearance of type Ⅰ, Ⅱ and Ⅲ bands, as well as exchanges between either type Ⅰand type Ⅱ or type Ⅰ and type Ⅲ bands. An increase of 0.2-17.6% cytosine methylated CCGG sites were detected in plantlets exposed to 10- 200 mmol/L salt compared to the control, and these changes included both de novo methylation and demethylation events. Nine methylation related fragments were also recovered and sequenced, and one sharing a high sequence homology with the ethylene responsive element binding factor was identified. These results demonstrated clear DNA genetic and epigenetic alterations in planUets as a response to salt stress, and these changes may suggest a mechanism for plants adaptation under salt stress.

关键词： Brassica napus DNA-methylation genetic variation methylation sensitive amplified polymorphism salt stress.

Neural Network-Based State Estimation for Nonlinear Systems With Denial-of-Service Attack Under Try-Once-Discard Protocol

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IEEE/CAA Journal of Automatica Sinica 2024年第10期11卷 2182-2184页

作者： Xueli Wang Shangwei Zhao Ming Yang Xin Wang xiaoming wu the Key Laboratory of Computing Power Network and Information Security Ministry of EducationShandong Computer Science CenterQilu University of Technology(Shandong Academy of Sciences)Jinan 250014 Shandong Provincial Key Laboratory of Computer Networks Shandong Fundamental Research Center for Computer ScienceJinan 250014China Department of Automation Shanghai Jiao Tong UniversityShanghai 200240China

Dear Editor,This letter deals with state estimation issues of discrete-time nonlinear systems subject to denial-of-service(DoS)attacks under the try-once-discard(TOD)*** specifically,to reduce the communication burden,a TOD protocol with novel update rules on protocol weights is designed for scheduling measurement *** addition,unknown nonlinear functions vulnerable to DoS attacks are considered due to the openness and vulnerability of the network.

关键词： Service DoS service

Ag_(2)Se Complex Nanostructures with Photocatalytic Activity and Superhydrophobicity

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Nano Research 2010年第12期3卷 863-873页

作者： Huaqiang Cao Yujiang Xiao Yuexiang Lu Jiefu Yin Baojun Li Shuisheng wu xiaoming wu Department of Chemistry Tsinghua UniversityBeijing 100084China School of Chemistry and Chemical Engineering Central South UniversityChangsha 410083China College of Chemistry and Chemical Engineering Hunan UniversityChangsha 410082China School of Chemistry and Chemical Engineering Nanjing UniversityNanjing 210093China

Single-crystalline Ag_(2)Se complex nanostructures have been synthesized via a solvothermal route in which selenophene(C4H4Se)as a selenylation source reacts with AgNO3 at a temperature of 240°*** orthorhombic phaseβ-Ag_(2)Se nanostructure was identified by X-ray diffraction(XRD),Raman spectroscopy,field emission scanning electron microscopy(FE-SEM),high resolution transmission electron microscopy(HRTEM),and photoluminescence(PL)*** wettability of the as-synthesizedβ-Ag_(2)Se nanostructure was studied by measurement of the water contact angle(CA).Static water CA values of over 150°were obtained,which can be attributed to theβ-Ag_(2)Se complex nanostructure having a combination of micro-and *** superhydrophobic Ag_(2)Se nanostructure may find applications in ***,the photocatalytic activity of the as-synthesizedβ-Ag_(2)Se nanostructure was evaluated by photodegradation of rhodamine B(RhB)dye under ultraviolet(UV)light irradiation.

关键词： Nanostructures photocatalytic photoluminescence superhydrophobicity silver selenide

Effectiveness of Qingre Lishi Yishen decoction on the glomerular fibrosis of immunoglobulin A nephropathy in a rat’s model

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Journal of Traditional Chinese Medicine 2019年第4期39卷 516-523页

作者： Dang Wanyu Hou Linyi Yan Huimin wu xiaoming Zhen Xiaofang Hao Jing Department of Traditional Chinese Medicine Beijing Children’s HospitalCapital Medical UniversityNational Center for Children’s healthCapital Medical UniversityNational Center for Children's healthBeijing 100045China

OBJECTIVE: To investigate the effect of the clinical effective prescription of Qingre Lishi Yishen decoction(QRLS) on the activation of mesangial cells in immunoglobulin A nephropathy(IgAN) ***: IgAN rat’s model was established by combine with intragastric administration of bovine serum albumin(BSA) + intravenous injection of lipopolysaccharide(LPS) by + subcutaneous injection of carbon tetrachloride(CCL4). Then the animals were randomly divided into four groups: control group, IgAN model group, IgAN model with Valsartan(Val) treatment group and IgAN model with QRLS treatment group. To observe the indexes of 24-h urine protein, renal function, deposition of immune complexes, expression of activation factor, fibrosis marker and inflammatory cytokines in four different ***: The Val or QRLS treatment group:(a) it reduced the immune complexes deposition of IgA in glomerular mesangial and inhibited mesangial cell proliferation;(b) it decreased the expression of smooth muscle actin(α-SMA), fibronectin(FN) and tumor necrosis factor alpha(TNF-α).CONCLUSION: The study suggested that QRLS ameliorate renal structure and function in IgAN rat’s model. Furthermore, we also observed that QRLS alleviated mesangial cells activation and matrix accumulation partly by decreasing the α-SMA,then to downregulated the expression of FN and TNF-α.

关键词： Glomerulonephritis,IGA Mesangial cells Fibronectins Tumor necrosis factor-alpha Qingre Lishi Yishen decoction

中国学术文化的自我主张与建设中华民族现代文明——访复旦大学吴晓明教授

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马克思主义理论学科研究 2023年第12期9卷 4-13页

作者：户晓坤吴晓明中山大学马克思主义哲学与中国现代化研究所暨哲学系广东广州510275 复旦大学

习近平在文化传承发展座谈会上的讲话中指出:“中国文化源远流长,中华文明博大精深。只有全面深入了解中华文明的历史,才能更有效地推动中华优秀传统文化创造性转化、创新性发展,更有力地推进中国特色社会主义文化建设,建设中华民族现... 详细信息

习近平在文化传承发展座谈会上的讲话中指出:“中国文化源远流长,中华文明博大精深。只有全面深入了解中华文明的历史,才能更有效地推动中华优秀传统文化创造性转化、创新性发展,更有力地推进中国特色社会主义文化建设,建设中华民族现代文明。”

关键词：中国式现代化中国学术文化马克思主义中国化时代化自我主张

Detection of DNA methylation changes during seed germination in rapeseed (Brassica napus)

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Chinese Science Bulletin 2006年第2期51卷 182-190页

作者： LU Guangyuan wu xiaoming CHEN Biyun GAO Guizhen XU Kun LI Xiangzhi Key Laboratory of Oil Crops Genetic Improvement of the Ministry of Agriculture Oil Crops Research Institute CAAS Wuhan 430062 China

DNA methylation is known to play a crucial role in regulating plant development and or- gan or tissue differentiation. In this study, we as- sessed the extent and pattern of cytosine methylation during rapeseed (Brassica napus L.) seed germina- tion, and compared the methylation level of various tissues in seedling, using the techniques of methyla- tion-sensitive amplified polymorphism (MSAP) and HPLC separation and quantification of nucleosides. In all, 484 bands, each representing a recognition site cleaved by either or both of the isoschizomers, were amplified by 12 pairs of selective primers in DNA ob- tained from dry seeds. A total of 76 sites were found to be differentially digested by the isoschizomers, indicating that approximately 15.7% of 5′-CCGG-3′ sites in the genome were cytosine methylated. Four classes of patterns were observed in a comparative assay of cytosine methylation in the dry and germi- nating seeds; a small number of hypermethylation events occurred at 5′-CCGG-3′ sites in germinating seeds compared with dry seeds, while many more hypomethylation events were detected after seed germination. Differences in DNA methylation level in various tissues were also detected; radicel was less methylated than hypocotyl and cotyledon. These observations were further confirmed by HPLC analy- sis. In addition, sequencing of eleven differentially methylated fragments and the subsequent blast search revealed that cytosine methylated 5′-CCGG- 3′ sequences were equally distributed between cod- ing and non-coding regions. These results clearly demonstrate the power of MSAP technique for large-scale DNA methylation detection in rapeseed genome, and the complexity of DNA methylationchange during seed germination. DNA Hypomethyla- tion going with seed germination appears to be a necessary step toward transcriptional activation in gene expression, and may well contribute to the de- velopmental gene regulation.

关键词：油菜籽芸苔属 DNA甲基化作用种子萌芽 MSAP HPLC